Local infusion of brain-derived neurotrophic factor modifies the firing pattern of dorsal raphé serotonergic neurons

Brain Research

Volumn 712, Issue 2, 1996, Pages 293-298

  Celada, Pau ^a   Siuciak, Judith A ^b   Tran, Tuan M ^a   Altar, C Anthony ^b   Tepper, James M ^a  

^a RUTGERS UNIVERSITY   (United States)

^b REGENERON PHARMACEUTICALS INC   (United States)

Author keywords

BDNF; Brain derived neurotrophic factor; Firing pattern; Growth factor; Serotonin

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; PINDOLOL; SEROTONIN AGONIST;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; MALE; NERVE CELL EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; RAPHE NUCLEUS; RAT; SEROTONINERGIC NERVE CELL;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; ELECTROPHYSIOLOGY; INJECTIONS; MALE; MESENCEPHALON; NERVE TISSUE PROTEINS; NEURONS; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN;

EID: 0029866084     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(95)01469-1     Document Type: Article

References (46)

1. Aghajanian, G.K., Foote, W.E. and Sheard, M.H., Action of psychotogenic drugs on single midbrain raphé neurons, J. Pharmacol. Exp. Ther., 171 (1970) 178-187.
2. Aghajanian, G.K. and Haigler, H.J., L-Tryptophan as a selective histochemical marker for serotoncrgic neurons in single-cell recording studies, Brain Res., 81 (1974) 364-372
3. Aghajanian, G.K. and VanderMaelen, C.P., Intracellular recordings from serotonergic dorsal raphé neurons: pacemarker potentials and the effect of LSD, Brain Res., 238 (1982) 463-469.
4. Aghajanian, G.K. and VanderMaelen, C.P., Intracellular identification of central noradrenergic and serotonergic neurons by a new double labeling procedure, J. Neurosci., 2 (1982) 1786-1792.
5. Aghajanian, G.K., Wang, R.Y. and Baraban, J., Serotonergic and non-serotonergic nerons of the dorsal raphé: reciprocal changes in firing induced by peripheral nerve stimulation, Brain Res., 153 (1978) 169-175.
6. Altar, C.A., Boylan, C.B., Jackson, C., Lindsay, R.M. and Hyman, C., Brain-derived neurotrophic factor augments rotational behavior and nigrostriatal dopamine turnover in vivo, Proc. Natl. Acad. Sci. USA, 89 (1992) 11347-11351.
7. Altar, C.A., Boylan, C.B., Fritsche, M., Jackson, C., Lindsay, R.M. and Hyman, C., The neurotrophins NT-4/5 and BDNF augment serotonin, dopamine, and GABAergic systems during behaviorally effective infusions to the substantia nigra, Exp. Neurol., 130 (1995) 31-40.
8. 125I] neurotrophin-3 binding to mammalian brain, J. Neurosci., 13 (1993) 733-743.
9. Azmitia, E.C. and Segal, M., An autoradiographic analysis of the differential ascending projections of the dorsal and median raphé nuclei in the rat, J. Comp. Neural., 179 (1978) 641-668.
10. Bramwell, G.J., Factors affecting the activity of 5-HT-containing neurones, Brain Res., 79 (1974) 515-519.
11. Descarries, L., Watkins, K.C., Garcia, S., Beaudet, A., The serotonin neurons in nucleus raphé dorsalis of adult rat: a light and electron microscope radioautographic study, J. Comp. Neural., 207 (1982) 239-254.
12. 1A receptors, Eur. J. Pharmacol., 237 (1993) 283-291.
13. 1A agonist, on the firing of serotonergic dorsal raphé neurons in the rat brain slice, Soc. Neurosci. Abstr., 13 (1987) 1649.
14. Gonon, F.G., Non linear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry, Neuroscience, 24 (1988) 19-28.
15. Gonon, F.G., Suaud-Chagny, M.F., Mermet, C.C. and Buda, M., Relation between impulse flow and extracellular catecholamine levels as studied by in vivo electrochemistry in CNS. In K. Fuxe and L.F. Agnati (Eds) Volume Transmission in the Brain : Novel Mechanisms for Neural Transmission, Raven Press, New York, 1991, pp. 337-350.
16. Heym, J., Steinfels, G.F. and Jacobs, B.L., Chloral hydrate anesthesia alters the responsiveness of central serotonergic neurons in the cat, Brain Res., 291 (1984) 63-72.
17. 1A receptor agonist, 8-OH-DPAT, preferentially activates cell body 5-HT autoreceptors in rat brain in vivo, Naunyn-Schmiedeberg's Arch. Pharmacol., 338 (1988) 463-471.
18. Hofer, M., Pagliusi, S.R., Hohn, A., Leibrock, J. and Barde, Y.A., Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain, EMBO J., 9 (1990) 2459-2464.
19. Jacobs, B.L., Heym, J. and Steinfels, G.F., Physiological and behavioral analysis of raphe unit activity, In L.L. Iversen, S.D. Iversen and S.H. Snyder (Eds.), Handbook of Psychopharmacology Vol. 18, Plenum Press, New York, 1984, pp. 343-395.
20. Lindsay, R.M., Weigand, S.J., Altar, C.A. and DiStefano, P.S., Neurotrophic factors: From molecules to man, Trends Neurosci., 17 (1994) 182-190.
21. Maisonpierre, P.C., Belluscio, L., Friedman, B., Alderson, R.F., Wiegand, S.J., Furth, M.E., Lindsay, R.M. and Yancopoulos, G.D., NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression, Neuron, 5 (1990) 501-509.
22. Mamounas, L.A., Blue, M.E., Siuciak, J.A. and Altar, C.A., BDNF promotes the survival and sprouting of serotonergic axons in rat brain, J. Neurosci., 15 (1995) 7929-7939.
23. Martin-Iverson, M.T., Todd, K.G. and Altar, A., Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: interactions with amphetamine, J. Neurosci., 14 (1994) 1262-1270.
24. Merlio, J.P., Ernfors, P., Jaber, M. and Persson , H., Molecular cloning of rat trkC and distribution of cells expressing messenger RNAs for members of the trk family in the rat central nervous system, Neuroscience, 51 (1992) 513-532.
25. Mufson, E.J., Kroin, J.S., Sobreviela, T., Burke, M.A., Kordower, J.H., Penn, R.D. and Miller, J.A., Intrastriatal infusions of BDNF: Regrograde transport and colocalization with dopamine containing substantia nigra neurons in rat, Exp. Neurol., 129 (1994) 15-26.
26. Park, M. Imai, R. and Kitai, H., Morphology and intracellular responses of an identified dorsal raphe projection neuron, Brain Res., 240 (1982) 321-326.
27. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, Sydney, 1982.
28. Pelleymounter, M.A., Cullen, M.J. and Wellman, C.L., Characteristics of BDNF-induced weight loss, Exp. Neurol., 131 (1995) 229-238.
29. Sawyer, S.F., Tepper, J.M., Young, S.J. and Groves, P.M., Antidromic activation of dorsal raphé neurons from neostriatum: physiological characterization and effects of terminal autoreceptor activation, Brain Res., 332 (1985) 15-28.
30. Shen, R., Altar, C.A. and Chiodo, L.A., Chronic supranigral infusion of BDNF increases the electrophysiological activity of pars compacta dopamine neurons, Proc. Natl. Acad. Sci. USA, 91 (1994) 8920-8924.
31. Siuciak, J.A., Altar, C.A., Wiegand, S.J. and Lindsay, R.M., Antinociceptive effect of brain-derived neurotrophic factor and neurotrophin-3, Brain Res., 633 (1994) 326-330.
32. Siuciak, J.A., Boylan, C.B., Fritsche, M. Altar, C.A. and Lindsay, R.M., BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration, Brain Res., in press.
33. Siuciak, J.A., Wiegand, S.J. and Lindsay, R.M., Antidepressant-like effect of brain-derived neurotrophic factor (BDNF), Neuropsychopharmacology, 10 Suppl. (1994) 187S.
34. Siuciak, J.A., Wong, V., Pearsall, D., Wiegand, S.J. and Lindsay, R.M., BDNF produces analgesia in the formalin test and modifies neuropeptide levels in rat brain and spinal cord areas associated with nociception, Eur. J. Neurosci., 7 (1995) 663-670.
35. Steinbusch, H.W.M., van der Kooy, D., Verhofstad, A.A.J. and Pellegrino, A., Serotonergic and non-serotonergic prejections from the nucleus raphé dorsalis to the caudate-putamen complex in the rat, studied by a combined immunofluorescence and fluorescent retrograde axonal labeling technique, Neurosci. Lett., 19 (1980) 137-142.
36. Steinbusch, H.W.M. and Nieuwenhuys, R., The raphé nuclei of the rat brainstem: a cytoarchitectonic and immunohistochemical study. In P.C. Emson (Ed.), Chemical Neuroanatomy, Raven Press, New York, 1984, pp. 131-207.
37. Tao, R. and Auerbach, S.B., Anesthetics block morphine-induced increases in serotonin release in rat CNS, Synapse, 18 (1994) 307-314.
38. Tepper, J.M., Creese, I. and Schartz, D.H., Stimulus-evoked changes in neostriatal dopamine levels in awake and anesthetized rats measured by microdialysis, Brain Res., 559 (1991) 283-292.
39. Tepper, J.M., Trent, F. and Nakamura, S., Postnatal development of the electrical activity of rat nigrostriatal dopaminergic neurons, Dev. Brain Res., 54 (1990) 21-33.
40. VanderMaelen, C.P. and Aghajanian, G.K, Electrophysiological and pharmacological characterization of serotonergic dorsal raphé neurons recorded extracellularly and intracellularly in rat brain slices, Brain Res., 289 (1983) 109-119.
41. Wang, R.Y. and Aghajanian, G.K., Antidromically identified serotonergic neurons in the rat midbrain raphé: evidence for collateral inhibition, Brain Res., 132 (1977) 186-193.
42. Wang, Q.-P. and Nakai, Y., The dorsal raphé: An important nucleus in Pain modulation, Brain Res. Bull., 34 (1994) 575-585.
43. Wetmore, C., Cao, Y., Pettersson, R.F. and Olson, L., BDNF: Subcellular compartmentalization and internuronal tranfer as visualized with anti-peptide antibodies, Proc. Natl. Acad. Sci. USA, 88 (1991) 9843-9847.
44. Wetmore, C., Ernfors, P., Persson, H. and Olson, L., Localization of brain derived neurotrophic factor mRNA to neurons in the brain by in situ hybridization, Exp. Neural., 109 (1990) 141-152.
45. 125I]-labeled neurotrophins in the central nervous system, Soc. Neurosci. Abstr., 17 (1991) 1121.
46. Yan, Q., Matheson, C., Sun, J., Radeke, M.J., Feinstein, S.C. and Miller, J.A., Distribution of intracerebroventricularly administratered neurotrophins in rat brain and its correlation with Trk receptors expression, Exp. Neural., 127 (1994) 23-36.