Repeated infusions of TNF-a cause attenuation of the thermal response and influence LPS fever in guinea pigs

American Journal of Physiology

Volumn 270, Issue 4 PART 2, 1996, Pages

  Goldbach, Jörg Michael ^a   Roth, Joachim ^a   Störr, Birgit ^a   Zeisberger, Eugen ^a  

^a UNIVERSITY HOSPITAL GIESSEN   (Germany)

Author keywords

Cytokines; Radiotelemetry; Temperature regulation; Tolerance; Tumor necrosis factor

Indexed keywords

ESCHERICHIA COLI LIPOPOLYSACCHARIDE; LYMPHOTOXIN; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; CROSS TOLERANCE; FEVER; GUINEA PIG; MALE; NONHUMAN; PRIORITY JOURNAL; TELEMETRY; THERMOREGULATION;

ABDOMEN; ANIMALS; BODY TEMPERATURE; FEVER; GUINEA PIGS; INJECTIONS, INTRA-ARTERIAL; LIPOPOLYSACCHARIDES; MALE; REACTION TIME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0029865847     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Bernardini, R., T. C. KamiLaris, A. E. Calogero, E. O. Johnson, M. T. Gomez, P. T. Gold, and G. P. Chrousos. Interactions between tumor necrosis factor-a, hypothalamic corticotropin-releasing hormone, and adrenocorticotropin secretion in the rat. Endocrinology 126: 2876-2881, 1990.
2. Beutler, B., and A. Cerami. Cachectin and tumor necrosis factor as two sides of the same biological coin. Nature Lo/id. 320: 584-588, 1986.
3. Beutler, B., and A. Cerami. Cachectin: more than a tumor necrosis factor. N. Engl. J. Med. 316: 379-385, 1987.
4. Busbridge, N. J., M. J. Dascombe, and N. J. Roth well. Chronic effects of interleukin-lß on fever, oxygen consumption and food intake in the rat. Harm. Metab. Res. 25: 222-227, 1993.
5. Cooper, A. L., S. Brouwner, A. V. Turnbull, G. N. Luheshi, S. J. Hopkins, S. L. Kunkel, and N. J. Rothwell. Tumor necrosis factor-a and fever after peripheral inflammation in the rat. Am. J. Physiol. 267 (Regulatory Integrative Comp. Physiol. 36):R1431-R1436, 1994.
6. Dinarello, C. A. The proinflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of the septic shock syndrome. J. Infect. Dis. 163: 1177-1184, 1991.
7. Dinarello, C. A., J. G. Cannon, S. M. Wolff, H. A. Bernheim, B. Beutler, A. Cerami, J. S. Figari, M. A. Palladino, and J. V. O'Connor. Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J. Exp. Med. 163: 1433-1450, 1986.
8. Ebisui, O., J. Fukata, N. Murakami, H. Kobayashi, H. Segawa, S. Mura, I. Hanaoaka, Y. Naito, Y. Masui, Y. Ohmoto, H. Imura, and K. Nakao. Effect of IL-1 receptor antagonist and antiserum to TNF-a on LPS-induced plasma ACTH and corticosterone rise in rats. Am. J. Physiol. 266 (Endocrinol. Metab. 29): E986-E992, 1994.
9. Fong, Y., K. J. Tracey, L. L. Moldawer, D. G. Hesse, K. R. Maogue, J. S. Kenney, A. T. Lee, G. C. Kuo, A. C. Allison, S. F. Lowry, and A. Cerami. Antibodies to cachectin/TNF reduce interleukin-lß and interleukin-6 appearance during lethal bacteremia. J. Exp. Med. 170: 1627-1633, 1989.
10. Kettelhut, J. C., and A. L. Goldberg. Tumor necrosis factor can induce fever in rats without activating protein breakdown in muscle or lipolysis in adipose tissue. J. Clin. Invest. 81: 13841389, 1988.
11. Klir, J. J., J. L. McClellan, W. Kozak, Z. Szelenyi, G. H. W. Wong, and M. J. Kluger. Systemic but not central administration of tumor necrosis factor-a attenuates LPS-induced fever in rats. Am. J. Physiol. 268 (Regulatory Integrative Comp. Physiol. 37): R480-R486, 1995.
12. Kluger, M. J. Fever: role of pyrogens and cryogens. Phvsiol. Rev. 71:93-127,1991.
13. Kozak, W., D. Soszynski, M. Szewczenko, and M. Bodurka. Lack of pyrogenic tolerance transmission between brain and periphery in the rabbit. Experientia Basel 46: 1010-1011, 1990.
14. Long, N. J., S. L. Kunkel, A. J. Vander, and M. J. Kluger. Antiserum against tumor necrosis factor enhances lipopolysaccharide fever in rats. Am. J. Physiol. 258 (Regulatory Integrative Comp. Physiol. 27): R332-R337, 1990.
15. Michie, H. R., D. R. Spriggs, K. R. Kanogue, M. L. Sherman, A. Revhaug, S. O'Dwyer, K. Arthur, C. A. Dinarello, A. Cerami, S. M. Wolff, D. W. Kufed, and W. Wilmore. Tumor necrosis factor and endotoxin induce similar metabolic responses in human beings. Surgery St. Louis 104: 280-286, 1988.
16. Roth, J., C. A. Conn, M. J. Kluger, and E. Zeisberger. Kinetics of systemic and intrahypothalamic IL-6 and tumor necrosis factor during endotoxin fever in guinea pigs. Am. J. Physiol. 265 (Regulatory Integrative Comp. Physiol. 34): R653R658,1993.
17. Roth, J., J. L. McClellan, M. J. Kluger, and E. Zeisberger. Attenuation of fever and release of cytokines after repeated injections of lipopolysaccharide in guinea pigs. J. Physiol. Land. 477: 177-185, 1994.
18. Roth, J., J. L. McClellan, M. J. Kluger, and E. Zeisberger. Changes in body temperature and circulating levels of interleukin-6 after intra-arterial injections or infusions of tumor necrosis factor a in guinea pigs. Experientia Basel 50: 815-820, 1994.
19. Roth, J., and E. Zeisberger. Endotoxin tolerance alters thermal response of guinea pigs to systemic infusions of tumor necrosis factor-. Am. J. Physiol. 268 (Regulatory Integrative Comp. Physiol. 37): R514-R519, 1995.
20. Rothwell, N. J. Central effects of TNFa on thermogenesis and fever in the rat. Biosci. Rep. 8: 345-352, 1988.
21. Shibata, M., and C. M. Blatteis. Human recombinant tumor necrosis factor and interferon affect the activity of neurons in the organum vasculosum laminae terminalis. Brain Res. 562: 323-326, 1991.
22. Shrader, R. E., and G. J. Everson. Intravenous injections and blood sampling using cannulated guinea pigs. Lab. Anim. Cam 18: 214-219, 1968.
23. Sozynski, D., W. Kozak. and M. Szewczenko. Course of fever response to repeated administration of sublethal doses of lipopolysaccharides, polyinosinic : polycytidylic acid and muramyl dipeptide to rabbits. Experientia Basel 47: 43-47, 1991.
24. Takahashi, N., P. Brouckaert, and W. Fiers. Mechanism of tolerance to tumor necrosis factor: receptor-specific pathway and selectivity. Am. J. Physiol. 269 (Regulatory Integrative Comp. Physiol. 38): R398-R405, 1995.
25. Van Zee, K. J., T. Kohno, E. Fischer, C. S. Rock, L. L. Moldawer, and S. F. Lowry. Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor in vitro and in vivo. Proc. Natl. Acad. Sei. USA 89: 4845-4849, 1992.
26. Watanabe, M. Characteristics of TNFa- and TNFß-induced fever in the rabbit. Jpn. J. Physiol. 42: 101-116, 1992.
27. Yamashiro, O., A. Morimoto, Y. Sakata, T. Watanabe, and N. Murakami. Febrile and metabolic tolerance to endotoxin and human recombinant interleukin-lß in rabbits. Am. J. Physiol. 264 (Regulatory Integrative Comp. Physiol. 33): R1180-R1185, 1993.