Silicon directed ipso-substitution of polymer bound arylsilanes: Preparation of biaryls via the Suzuki cross-coupling reaction

Tetrahedron Letters

Volumn 37, Issue 16, 1996, Pages 2703-2706

  Han, Yongxin ^a   Walker, Shawn D ^a   Young, Robert N ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIPHENYL DERIVATIVE;

ARTICLE; CATALYSIS; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029865824     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00364-4     Document Type: Article

References (31)

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23. 15
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27. In the reaction of the corresponding alcohol with HCl(g) and trioxane to yield linker 4, substantial amount of protiodesilylation (@50%) took place.
28. 2 afforded the same product in quantitative yield. P-4, however, reacted smoothly to afford 67% yield of the desired product (p-bromoanisole)
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31. Some of the corresponding benzylic chloride was also observed. See also: Takahashi, M.; Hatano K.; Kimura, M.; Watanabe, T.; Oriyama, T.; Koga, K. Tetrahedron Lett. 1994, 35, 579.