Antagonistic actions of renal dopamine and 5-hydroxytryptamine: Increase in Na+, K+-ATPase activity in renal proximal tubules via activation of 5-HT1A receptors

British Journal of Pharmacology

Volumn 117, Issue 6, 1996, Pages 1199-1203

  Soares Da Silva, P ^a   Pinto Do O P C ^a   Bertorello, A M ^b  

^a Inst of Pharmacol and Therapeutics   (Portugal)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

5 hydroxytryptamine receptors; Dopamine; Kidney tubules; Natriuresis

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALPHA METHYLSEROTONIN; DOPAMINE; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; SEROTONIN; SEROTONIN 1A RECEPTOR;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; KIDNEY PROXIMAL TUBULE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; KIDNEY TUBULES, PROXIMAL; MALE; NA(+)-K(+)-EXCHANGING ATPASE; PIPERAZINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS;

EID: 0029865749     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb16716.x     Document Type: Article

References (28)

1. + -ATPase and solute transport in rabbit proximal tubules. Am. J. Physiol., 252, F215-F220.
2. +) ATPase in neostriatal neurons through dopamine receptor synergism. Nature, 347, 386-388.
3. BERTORELLO, A.M. & KATZ, A.I. (1993). Short-term regulation of renal Na-K-ATPase activity: physiological relevance and cellular mechanisms. Am. J. Physiol., 265, F743-55.
4. BLACKSHEAR, J.L., ORLANDI, C, & HOLLENBERG, N.K. (1991). Constrictive effect of serotonin on visible renal arteries: A pharmacoangiographic study in anaesthetized dogs. J. Cardiovasc. Pharmacol., 17, 68-73.
5. BRADFORD, M.M. (1976). A rapid method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
6. CLIFFE, I.A., BRIGHTWELL, C.J., FLETCHER, A., FORSTER, E.A., MANSELL, H.L., REILLY, Y., ROUTLEDGE, C. & WHITE, A.C. (1993). (S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropionamide [(S)-WAY 100135]: A selective antagonist at presynaptic and postsynaptic 5-HT1A receptors. J. Med. Chem., 36, 1509-1510.
7. FELDER, C.C., CAMPBELL, T., ALBRECHT, F. & JOSE, P.A. (1990). Dopamine inhibits Na(+)-H + exchanger activity in renal BBMV by stimulation of adenylate cyclase. Am. J. Physiol., 259, F297-303.
8. FREDERICH, F. PAULMICHL, M., KOLB, A. & LANG, F. (1988). Inward rectifier K channels in renal epitheloid cells (MDCK) activated by serotonin. J. Membr. Biol., 106, 149-155.
9. GOPALAKRISHNAN, S.M., CHEN, C. & LOKHANDWALA, M.F. (1995). Alphal-adrenoceptor subtypes mediating stimulation of Na + -K + -ATPase activity in rat renal proximal tubules. Eur. J. Pharmacol., 288, 139-147.
10. HAMAMORI, Y., HOSHIJIMA, M., OHMURI, T., UEDA, T. & TAKAI, Y. (1988). Serotonin as a major serum factor inducing the phospholipase C-mediated hydrolysis of phosphoionosited in normal rat kidney cells. Cancer Res., 48, 6697-6702.
11. IBARRA, F., APERIA, A., SVENSSON, L.-B., EKLOF, A.C. & GREENGARD, P. (1993). Bidirectional regulation of Na + -K + -ATPase activity by dopamine and an alpha-adrenergic agonist. Proc. Natl. Acad. Sci. U.S.A., 90, 21-24.
12. ITSKOWITZ, H.D., CHEN, Y.H. & STIER, C., Jr. (1988). Reciprocal renal effects of dopamine and 5-hydroxtryptamine formed within the rat kidney. Clin. Sci., 75, 503-507.
13. JANSSENS, W.J. & VAN NUETEN, J.M. (1986). The direct and amplifying effects of serotonin are increased with age in the isolated perfused kidney of Wistar and spontaneously hypertensive rats. Naunyn-Schmied. Arch. Pharmacol., 334, 327-332.
14. LEE, M.R. (1993). Dopamine and the kidney: ten years on [Editorial]. Clin. Sci., 84, 357-375.
15. LI KAM WA, T.C. FREESTONE, S., SAMSON, R.R., JOHNSON, N.R. & LESS, M.R. (1993). A comparison of the renal and neuroendocrine effects of two 5-hydroxytryptamine renal prodrugs in normal man. Clin. Sci., 85, 607-614.
16. MIDDLETON, J.P., RAYMOND, J.R., WHORTON, A.R. & DENNIS, V.W. (1990). Short-term regulation of Na + /K+ adenosine triphosphatase by recombinant human serotonin 5-HT1A receptor expressed in HeLa cells. J. Clin. Invest., 86, 1799-1805.
17. MURPHY, T.J. & BYLUND, D.B. (1990). Characterization of serotonin-1B receptors negatively coupled to adenylated cyclase in OK cells, a renal epithelial cell line from the Opossum. J. Pharmacol. Exp. Ther., 249, 535-543.
18. RAYMOND, J.R., KIM, J., BEACH, R.E & TISHER, C.C. (1993). Immunohistochemical mapping of cellular and subcellular distribution of 5-HT1A receptors in rat and human kidneys. Am. J. Physiol., 264, F9-F19.
19. SCHMIDT, W. & PEROUTKA, S.J. (1989). 5-Hydroxytryptamine receptor families. FASEB J., 3, 2242-2249.
20. SEGEL, I.H. (1975). Enzyme Kinetics: Behaviour Analysis of Rapid Equilibrium and Steady-State Enzyme Systems. New York: John Wiley.
21. SHOJI, T., TAMAKI, T., FUKUI, K., IWAO, H. & ABE, Y. (1989). Renal hemodynamic responses to 5-hydroxytryptamine (5-HT): involvement of the 5-HT receptor subtypes in the canine kidney. Eur. J. Pharmacol., 171, 219-228.
22. SIRAGY, H.M., FELDER, R.A., HOWELL, N.L., CHEVALIER, R.L., PEACH, M.J. & CAREY, R.M. (1989). Evidence that intrarenal dopamine acts as a paracrine substance at the renal tubule. Am. J. Physiol., 257, F469-F477.
23. SOARES-DA-SILVA, P. & BERTORELLO, A.M. (1994). Activation of 5-hydroxytryptamine S-HT1A receptor subtype increase Na,K-ATPase activity from renal proximal tubules. J. Am. Soc. Nephrol., 5, 670.
24. SOARES-DA-SILVA, P., FERNANDES, M.H. & PINTO-DO-Ó, P.C. (1994a). Cell inward transport of L-DOPA and 3-O-methyl-L-DOPA in rat renal tubules. Br. J. Pharmacol., 112, 611-615.
25. SOARES-DA-SILVA, P. & PINTO-DO-Ó, P.C. (1996). Antagonistic actions of renal dopamine and 5-hydroxytryptamine. Effects of amine precursors on the cell inward transfer and decarboxylation. Br. J. Pharmacol., 117, 1187-1192.
26. SOARES-DA-SILVA, P., VIEIRA-COELHO, M.A. & PESTANA, M. (1994b). (+) WAY 100135 inhibits antinatriuresis following high sodium intake in conditions of monoamine oxidase inhibition. Br. J. Pharmacol., 112, 106P.
27. TAKUWA, N., GAN, M., TAKUWA, Y., STERZEL, R.B. & RASMUSSEN, H. (1989). Studies of the mitogenic effect of serotonin in rat mesangial cells. Am. J. Physiol., 257, F431-F439.
28. WRIGHT, C.E. & ANGUS, J.A. (1987). Diverse vascular responses to serotonin in the conscious rabbit: Effects of serotonin antagonists on renal artery spasm. J. Cardiovasc. Pharmacol., 10, 415-423.