메뉴 건너뛰기




Volumn 13, Issue 1, 1996, Pages 137-140

FK506 (tacrolimus) and its immunoreactive metabolites in whole blood of liver transplant patients and subjects with mild hepatic dysfunction

Author keywords

FK506; Hepatic dysfunction; HPLC ELISA; Immunoreactive metabolites; Liver transplantation; Tacrolimus

Indexed keywords

DRUG METABOLITE; TACROLIMUS;

EID: 0029865392     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016002005912     Document Type: Article
Times cited : (14)

References (12)
  • 6
    • 0027945930 scopus 로고
    • Measurement of blood concentrations of FK506 (tacrolimus) and its metabolites in seven liver graft patients after the first dose by h.p.l.e.-MS and microparticle enzyme immunoassay (MEIA)
    • A.-K. Gonschior, U. Christians, F. Braun, M. Winkler, A. Linck, J. Baumann, and K.-Fr. Sewing. Measurement of blood concentrations of FK506 (tacrolimus) and its metabolites in seven liver graft patients after the first dose by h.p.l.e.-MS and microparticle enzyme immunoassay (MEIA). Br. J. Clin. Pharmacol. 38: 567-571 (1994).
    • (1994) Br. J. Clin. Pharmacol. , vol.38 , pp. 567-571
    • Gonschior, A.-K.1    Christians, U.2    Braun, F.3    Winkler, M.4    Linck, A.5    Baumann, J.6    Sewing, K.-Fr.7
  • 7
    • 0026681640 scopus 로고
    • In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: Identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism
    • S. H. Vincent, B. V. Karanam, S. K. Painter, and S.-H. L. Chiu. In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: Identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism. Arch. Biochem. Biophys. 294: 454-460 (1992).
    • (1992) Arch. Biochem. Biophys. , vol.294 , pp. 454-460
    • Vincent, S.H.1    Karanam, B.V.2    Painter, S.K.3    Chiu, S.-H.L.4
  • 8
    • 0028295725 scopus 로고
    • Metabolism of FK506, a potent immunosuppressive agent, by cytochrome P450 3A enzymes in rat, dog and human liver microsomes
    • T. Shiraga, H. Matsuda, K. Nagase, K. Iwasaki, K. Noda, H. Yamazaki, T. Shimada, and Y. Funae. Metabolism of FK506, a potent immunosuppressive agent, by cytochrome P450 3A enzymes in rat, dog and human liver microsomes. Biochem. Pharmacol. 47: 727-735 (1994).
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 727-735
    • Shiraga, T.1    Matsuda, H.2    Nagase, K.3    Iwasaki, K.4    Noda, K.5    Yamazaki, H.6    Shimada, T.7    Funae, Y.8
  • 10
    • 0027379479 scopus 로고
    • Validation and quality assurance program for monitoring tacrolimus (FK 506) concentrations in plasma and whole blood
    • R. D'Ambrosio, N. Girzaitis, and W. J. Jusko. Validation and quality assurance program for monitoring tacrolimus (FK 506) concentrations in plasma and whole blood. Ther. Drug Monit. 15:414-426 (1993).
    • (1993) Ther. Drug Monit. , vol.15 , pp. 414-426
    • D'Ambrosio, R.1    Girzaitis, N.2    Jusko, W.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.