Synergistic binding of inhibitors to the protease from HIV type 1

Biochemical Journal

Volumn 315, Issue 1, 1996, Pages 113-117

  Asante Appiah, Ernest ^a   Chan, William W C ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOBENZYLOXYGLUTAMINYLISOAMYLAMIDE; CARBOBENZYLOXYISOLEUCINYLPHENYLALANILOL; PROTEINASE; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; BINDING AFFINITY; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; PROTEINASE INHIBITION; REACTION ANALYSIS;

EID: 0029865072     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3150113     Document Type: Article

References (30)

1. Mitsuya, H., Yarchoan, R. and Broder, S. (1990) Science 249, 1533-1543
2. Kohl, N. E., Emini, E. A., Schleif, W. A., Davis, L. J., Heimback, J. C., Dixon, R. A. F., Scolnick, E. M. and Sigal, I. S. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 4685-1690
3. Seelmeier, S., Schmidt, H., Turk, V. and von der Helm, K. (1988) Proc. Natl. Acad. Sci. USA 85, 6612-6616
4. Dreyer, G. B., Metcalf, B. W., Tomaszek, T. A., Jr., Carr, T. J., Chandler, A. C., III, Hyland, L., Fakhoury, S. A., Magaard, V. W., Moore, M. L., Strickler, J. E., Debouck, C. and Meek, T. D. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 9752-9756
5. McQuade, T. J., Tomasselli, A. G., Liu, L., Karacostas, V., Moss, B., Sawyer, T. K., Heinrikson, R. L. and Tarpley, W. G. (1990) Science 247, 454-456
6. Roberts, N. A., Martin, J. A., Kinchington, D., Broadhurst, A. V., Craig, J. C., Dunan, I. B., Galpin, S. A., Handa, B. K., Kay, J., Kröhn, A., Lambert, R. W., Merrett, J. H., Mills, J. S., Parkes, K. E. B., Redshaw, S., Ritchie, A. J., Taylor, D. L., Thomas, G. J. and Machin, P. J. (1990) Science 248, 358-361
7. Rich, D. H., Prasad, J. V. N. V., Sun, C.-Q., Green, J., Mueller, R., Houseman, K., MacKenzie, D. and Malkovsky, M. (1992) J. Med. Chem. 35, 3803-3812
8. Moore, M. L., Bryan, W. M., Fakhoury, S. A., Magaard, V. W., Huffman, W. F., Dayton, B. D., Meek, T. D., Hyland, L., Dreyer, G. B., Metcalf, B. W., Strickler, J. E., Gorniak, J. G. and Debouck, C. (1989) Biochem. Biophys. Res. Commun. 159, 420-425
9. Schneider, J. and Kent, S. B. H. (1988) Cell 54, 363-368
10. Wlodawer, A.; Miller, M., Jaskolski, M., Sathyanarayana, B. K., Baldwin, E., Weber, I., Selk, L., Clawson, K., Schneider, J. and Kent, S. B. H. (1989) Science 245, 616-621
11. Fitzgerald, P. M. D., McKeever, B. M., Van Middlesworth, J. F., Springer, J. P., Heimbach, J. C., Leu, C.-T., Herber, W. K., Dixon, R. A. F. and Drake, P. L. (1990) J. Biol. Chem. 265, 14209-14219
12. Swain, A. L., Miller, M. M., Green, J., Rich, D. H., Schneider, J., Kent, S. B. H. and Wlodawer, A. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 8805-8809
13. DiGregorio, M., Pickering, D. S. and Chan, W. W.-C. (1988) Biochemistry 27, 3613-3617
14. Chan, W. W.-C. and Pfuelzner, R. A. (1993) Eur. J. Biochem. 218, 529-534
15. Pfuelzner, R. A. and Chan, W. W.-C. (1993) Eur. J. Biochem. 218, 523-528
16. Pfuetzner, R. A. and Chan, W. W.-C. (1988) J. Biol. Chem. 263, 4056-4058
17. Sheehan, J. C. and Hess, G. P. (1955) J. Am. Chem. Soc. 23, 1067-1068
18. Konig, W. E. and Geiger, R. (1970) Chem. Ber. 103, 788-798
19. Darke, P. L., Nutt, R. F., Brady, S. F., Garsky, V. M., Ciccarone, T. M., Leu, C.-T., Lumma, P. K., Freidinger R. M., Veber, D. F. and Sigal, I. S. (1988) Biochem. Biophys. Res. Commun. 156, 297-303
20. Yonetani, T. and Theorell, H. (1964) Arch. Biochem. Biophys. 106, 243-251
21. Dixon, M. (1953) Biochem. J. 55, 170-171
22. Kempf, D. J., Norbeck, D. W., Codcovi, L., Wang, X.-C., Kohlbrenner, W. E., Wideburg, N.., Paul, D. A., Knigge, M. F., Vasavanonda, S., Craig-Kennard, A., Saldivar, A., Rosenbrook, W. Jr., Clement, J. J., Plattner, J. J. and Erickson, J. (1990) J. Med. Chem. 33, 2687-2689
23. Schechter, I. and Berger, A. (1967) Biochem. Biophys. Res. Commun. 27, 157-162
24. Erickson, J., Neidhart, D. J., VanDrie, J., Kempf, D. J., Wang, X.-C., Norbeck, D. W., Plattner, J. J., Rittenhouse, J. W., Turon, M., Wideburg, N., Kohlbrenner, W. E., Simmer, R., Helfrich, R., Paul, D. A. and Knigge, M. (1990) Science 249, 527-533
25. Griffiths, J. T., Phylip, L. H., Konvalinka, J., Strop, P., Gustchina, A., Wlodawer, A., Davenport, R. J., Briggs, R., Dunn, B. M. and Kay, J. (1992) Biochemistry 31, 5193-5200
26. Poorman, R. A., Tomasselli, A. G., Heinrikson, R. L. and Kézdy, F. J. (1991) J. Biol. Chem. 266, 14554-14561
27. Cameron, C. E., Grinde, B., Jacques, P., Jentoft, J., Leis, J., Wlodawer, A. and Weber, I. T. (1993) J. Biol. Chem. 268, 11711-11720
28. Citri, N. (1973) Adv. Enzymol. 37, 397-648
29. Jencks, W. P. (1981) Proc. Natl. Acad. Sci. U.S.A. 78, 4046-4050
30. Shaw, E. (1970) in The Enzymes (Boyer, P. D., ed.), vol. 1, pp. 91-146, Academic Press, London and New York