On the pathogenesis trail: What marker B cell clones tell us about inflammatory bowel disease

Canadian Journal of Gastroenterology

Volumn 10, Issue 2, 1996, Pages 115-119

  Braun, Jonathan ^a   Valles Ayoub, Yadrira ^a   Berberian, Linda ^a   Eggena, Mark ^a   Gordon, Lynn K ^a   Targan, Stephan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

B lymphocyte; Crohn's disease; Phage display antibody; Ulcerative colitis

Indexed keywords

GRANULOCYTE ANTIBODY;

ARTICLE; B LYMPHOCYTE; CAMPYLOBACTER JEJUNI; CROHN DISEASE; ENTERITIS; ENTEROCOLITIS; IMMUNOGENETICS; IMMUNOPATHOGENESIS; LABORATORY DIAGNOSIS; LYMPHOCYTE CLONE; PRIORITY JOURNAL; ULCERATIVE COLITIS;

EID: 0029865031     PISSN: 08357900     EISSN: None     Source Type: Journal    
DOI: 10.1155/1996/198982     Document Type: Article

References (23)

1. Tan EM. Autoantibodies in pathology and cell biology. Cell 1991;67:841-2.
2. Strober W, James SP. The immunologic basis of inflammatory bowel disease. J Clin Immunol 1986;6:414-32.
3. Targan SR, Kagnoff MF, Brogan MD, Shanahan F. Immunologic mechanisms in intestinal diseases. Ann Intern Med 1987;106:853-70.
4. MacDermott RP, Stenson WF. Alterations of the immune system in ulcerative colitits and Crohn's disease. Adv Immunol 1988;42:285-328.
5. Kagnoff MF. A question of balance: Ups and downs of mucosal inflammation. J Clin Invest 1994;94:1.
6. Mamula MJ, Fatenejad S, Craft J. B cells process and present lupus autoantigens that initiate autoimmune T cell responses. J Immunol 1994;152:1453-61.
7. Lin R-W, Mamula MJ, Hardin JA, Janeway CA. Induction of autoreactive B cells allows priming of autoreactive T cells. J Exp Med 1991;173:1433-9.
8. Korsmeyer SJ, Williams RC Jr, Wilson AO, Strickland RG. Lymphocytotoxic antibody in inflammatory bowel disease. A family study. N Engl J Med 1975;293:1117-20.
9. Lagercrantz R, Perlmann P, Hammarstrom S. Immunological studies in ulcerative colitis. V. Family studies. Gastroenterology 1971;60:381-9.
10. Fiocchi C, Roche JK, Michener WM. High prevalence of antibodies to intestinal epithelial antigens in patients with inflammatory bowel disease and their relatives. Ann Intern Med 1989;110:786-94.
11. Das KM, Vecchi M, Sakamaki S. A shared and unique epitope(s) on human colon, skin, and biliary epithelium detected by a monoclonal antibody. Gastroenterology 1990;98:464-9.
12. Stevens TR, Harley SL, Groom JS, et al. Anti-endothelial cell antibodies in inflammatory bowel disease. Dig Dis Sci 1993;38:426-32.
13. Lindberg E, Magnusson KE, Tysk C, Jamerot G. Antibody (IgG, IgA, and IgM) to baker's yeast (Saccharomyces cerevisiae), yeast manna, gliadin, ovalbumin, and betalactoglobulin in monozygotic twins with inflammatory bowel disease. Gut 1992;33:909-13.
14. O'Mahony S, Anderson N, Nuki G, Ferguson A. Systemic and mucosal antibodies to klebsiella in patients with ankylosing spondylitis and Crohn's disease. Ann Rheum Dis 1992;51:1296-300.
15. Elsaghier A, Prantera C, Moreno C, Ivanyi J. Antibodies to Mycobacterium paratuberculosis-specific protein antigens in Crohn's disease. Clin Exp Immunol 1992;90:503-8.
16. Saxon A, Shanahan F, Landers C, Ganz T, Targan S. A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease. J Allergy Clin Immunol 1990;86:202-10.
17. Duerr RH, Targan SR, Landers CJ, Sutherland LR, Shanahan F. Anti-neutrophil cytoplasmic antibodies in ulcerative colitis. Comparison with other colitides/diarrheal illnesses. Gastroenterology 1991;100:1590-6.
18. Yang H, Rotter JI, Toyoda H, et al. Ulcerative colitis: A genetically heterogeneous disorder defined by genetic (HLA class II) and subclinical (antineutrophil cytoplasmic antibodies) markers. J Clin Invest 1993;92:1080-4.
19. Kaulfersch W, Fiocchi C, Waldmann TA. Polyclonal nature of the intestinal mucosal lymphocyte populations in inflammatory bowel disease. A molecular genetic evaluation of immunoglobulin and T-cell antigen receptors. Gastroenterology 1988;95:364-70.
20. Berberian LS, Valles-Ayoub Y, King L, Gordon LK, Targan SR, Braun J. Expression of a novel autoantibody defined by the VH3-15 gene in inflammatory bowel disease and Campylobacter jejuni enterocolitis. J Immunol 1994;153:3756-63.
21. Graham DY. Campylobacter pylori and peptic ulcer disease. Gastroenterology 1989;96:615.
22. Blaser MJ, Hoverson D, Ely IG, Juncan DJ, Wang WL, Brown WR. Studies of Campylobocter jejuni in patients with inflammatory bowel disease. Gastroenterology 1984;86:33-8.
23. Persson MA, Caothien RH, Burton DR. Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning. Proc Natl Acad Sci USA 1991;88:2432-6.