Fluoro organics: A facile and exclusive synthesis of novel 2- or 4-trifluoromethyl(1H,5)arylodiazepines

Tetrahedron Letters

Volumn 37, Issue 16, 1996, Pages 2845-2848

  Chandra Sheker Reddy, A ^a   Shanthan Rao, P ^a   Venkataratnam, R V ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

DIAZEPINE DERIVATIVE; ORGANOFLUORINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0029864926     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00402-9     Document Type: Article

References (7)

1. Watthey, J.W.H.; Stanton, J.; Peet, N.P. in Azepines, Part 2, edited by Rosowsky, A. (John Wiley& sons) 1984.
2. Hojo, M.; Masuda, R.; Kokuryo, Y.; Shioda, H.; Matsuo, S. Chem. Lett., 1976,499.
3. Hojo, M.; Masuda, R.; Okada, E. Synthesis, 1990, 347.
4. Gedye, R.; Smith, F.; Westaway, K.; Baldisera, L.; Laberge, L.; Rousel, J. Tetrahedron Lett., 1986,27, 279.
5. Giguere, R.J.; Bray, T.L.; Duncan, S.M.; Majetich, G. Tetrahedron Lett., 1986,27,4945.
6. Bougrin, K.; Bennani, A.K.; Tetouani, S.F.; Soufiaoui, M. Tetrahedron Lett., 1994, 35,8373.
7. 3). 4a-δ 11.40 (d,br.,1H,NH); 8.00 (d,J=12.1 Hz,1H,H-C(4)); 6.60 -7.80 (m,3H,ArH); 5.70 (d,J=9.0 Hz,1H,H-C(3)). 4c-δ 11.10 (d,br.,1H,NH); 8.40 (s,1H,H-C(4)); 7.00-7.80 (m,3H,ArH).