Expression cloning and signal transduction pathway of P2U receptor in mammary tumor cells

NeuroSignals

Volumn 5, Issue 1, 1996, Pages 9-21

  Enomoto, Koh Ichi ^a   Furuya, Kishio ^b   Moore, Robert C ^c   Yamagishi, Shunichi ^b   Oka, Takami ^c   Maeno, Takashi ^a  

^a SHIMANE UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

ATP; Calcium; Inositol 1,4,5 trisphosphate; Mammary cell; P2U receptor; UTP

Indexed keywords

ADENOSINE TRIPHOSPHATE; BRADYKININ; CAFFEINE; CHOLERA TOXIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITIDE; PURINE P2 RECEPTOR; RYANODINE; SURAMIN; URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BREAST TUMOR; CALCIUM CELL LEVEL; CELL STRAIN K 562; CONTROLLED STUDY; DOSE RESPONSE; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHOINOSITIDE METABOLISM; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL;

ADENOSINE DIPHOSPHATE RIBOSE; ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CAFFEINE; CALCIUM; CELL LINE; CLONING, MOLECULAR; CYCLIC ADP-RIBOSE; DNA, COMPLEMENTARY; FEMALE; FLUORESCENT DYES; FURA-2; GTP-BINDING PROTEINS; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; LEUKEMIA; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLINOSITOLS; RECEPTORS, PURINERGIC P2; RYANODINE; SIGNAL TRANSDUCTION; SURAMIN; URIDINE TRIPHOSPHATE;

ANIMALIA;

EID: 0029864449     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000109169     Document Type: Article

References (35)

1. Enmoto K, Furuya K, Yamagishi S, Maeno T: Mechanically induced calcium response in mammary epithelial cells. Biomcd Res 1993; 14(suppl 2): 135-137.
2. Furuya K, Enomoto K, Yamagishi S: Spontaneous calcium oscillations and mechanically and chemically induced calcium responses in mammary epithelial cells. Pflügers Arch 1993;422:295-304.
3. 2+ concentration by mechanical stimulation is propagated via release of pyrophosphory-lated nucleotides in mammary epithelial cells. Pflügers Arch 1994;427: 533-542.
4. Huang N, Wang D, Heppel LA: Extracellular ATP is a mitogen for 3T3. 3T6 and A431 cells and acts synergistically with other growth factors. Proc Natl Acad Sci USA 1989:86:7904-7908.
5. Cockcroft S, Stutchfield J: ATP stimulates secretion in human neu-rophils and HL60 cells via a pertussis toxin-sensitive guanine nucleo-lide-binding protein coupled to phosphoiipase C, FEBS Lett 1989; 245:25-29.
6. Lustig KD, Erb L, Landis DM, Hicks-Taylor CS, Zhang X, Sportiel-lo MG, Weisman GA: Mechanisms by which extracellular ATP and UTP stimulate the release of prostacyclin from bovine pulmonary artery endothelial cells. Biochim Bio-physActa 1992;1134:61-72.
7. Xing M, Thevanod F, Mattera R: Dual regulation of arachidonic acid release by Piu purinergic receptors in dibutyryl cyclic AMP-differentiated HL60 cells. J Biol Chem 1992;267:6602-6610.
8. Turner MD, Rennison ME, Handel SE, Wilde CJ, Burgoyne RD: Proteins are secreted by both constitutive and regulated secretory pathways in lactating mouse mammary epithelial cells. J Cell Biol 1992;117: 269-278.
9. Katsuragi T, Tokunaga T, Ogawa S, Soejima O, Sato C, Furukawa T: Existence of ATP-cvoked ATP release system in smooth muscles. J Pharmacol ExpTher 1991;259:513-518.
10. Lustig KD, Shiau AK, Brake AJ, Julius D: Expression cloning of an ATP receptor from mouse neuroblastoma cells. Proc Natl Acad Sci USA 1993;90:5113-5117.
11. Parr CE, Sullivan DM, Paradiso AM, Lazarowski ER, Buch LH, Olsen JC, Erb L, Weisman GA, Boucher RC, Turner JT: Cloning and expression of a human Pjq nucleotide receptor, a target for cystic fibrosis pharmacotherapy. Proc Natl Acad Sci USA 1994:91:3275-3279.
12. Rice WR, Burton FM, Fiedeldcy DT: Cloning and expression of the alveolar type II cell P2u-purincrgic receptor. Am J Rcspir Cell Mol Biol 1995;12:27-32.
13. 2* indicators with greatly improved fluorescence properties. J Biol Chem 1985;60:3440-3450.
14. Enomoto K, Furuya K, Yamagishi S, Maeno T: Mechanically induced electrical and intracellular calcium responses in normal and cancerous mammary cells. Cell Calcium 1992; 13:501-511.
15. Kendall DA, Whitworth P: Lithium amplifies inhibitions of inositol hydrolysis in mammalian brain slices. Br J Pharmacol 1990;100:723-728.
16. Hamill OP, Marty A, Neher E, Sak-niann B, Sigworth FJ: Improved patch-clamp techniques for high-re-solution current recording from cells and cell-free membrane patches. PfiugcrsArch 1981;391:85-100.
17. Enomoto K, Furuya K, Yamagishi S, Maeno T: Proliferation-associated increase in sensitivity of mammary epithelial cells to inositol-1,4,5-trisphosphate. Cell Biochem Funct 1993;11:55-62.
18. Rojas E, Pollard H, Heldman E: Real-time measurements of acetylcholine-induced release of ATP from bovine medullary chromaffin cells. FEBS Lett 1985;185:323-327.
19. Fredhorm BB, Abbracchio MP, Bumstock G, Daly JW, Harden TK, Jacobson KA, Lef TP, Williams AM: Nomenclature and classification of purinoceptors. Pharmacol Rev 1994;46:143-156.
20. Dunn PM, Blakeley AGH: Suramin: A reversible Pi-purinoceptor antagonist in the mouse vas deferens. Br J Pharmacol 1988;93:243-245.
21. Lef TP, Wood BE, O’Connor SE: Suramin is a slowly equilibrating but competitive antagonist at Pjx-recep-tors in the rabbit isolated ear artery. Br J Pharmacol 1990;101:645-649.
22. Ogura A, Myojo Y, Higashida H: Bradykinin-evoked acetylcholine release via inositol trisphosphate-de-pendent elevation in free calcium in neuroblastoma x glioma hybrid NG108-15 cells. J Biol Chem 1990; 265:3577-3584.
23. Osugi T, Imaizumi T, Mizushima A, Uchida S, Yoshida HTI: Role of a protein regulating guanine nucleotide binding in phosphoinositide breakdown and calcium mobilization by bradykinin in neuroblastoma x glioma hybrid NG108-15 cells: Effects of pertussis toxin and cholera toxin on receptor-mediated signal transduction. Eur J Pharmacol 1987; 137:207-218.
24. Endo M: Calcium release from the sarcoplasmic reticulum. Physiol Rev 1977;57:71-108.
25. Lai FA, Erickson HP, Rousseau E, Liu QY, Meissner G: Purification and reconstitution of the calcium release channel from skeletal muscle. Nature 1988;331:315-319.
26. 2+ release and its modulation by cyclic ADP-ribose. Trends Pharmacol Sci 1992;13:304-306.
27. Davidson JS, Wakefield IK, Sohnius U, van der Mcrwe PA, Miller PR: A novel extracellular nucleotide receptor coupled to phosphoinositi-dase-C in pituitary cells. Endocrinology 1990;126:80-87.
28. 2-purinergic receptors for extracellular ATP. J Biol Chem 1988,263: 18108-18117.
29. 2+]i increase and InsPj generation following stimulation ofNIE-l 15 cells with micromolar and millimolar ATP. Bio-chem Pharmacol 1992;44:1479-1487.
30. Lustig KD, Sportiello MG, Erb L, Weisman GA: A nucleotide receptor in vascular endothelial cells is specifically activated by the fully ionized forms of ATP and UTP. Bio-chemJ 1992;284:733-739.
31. Rcber BFX, Neuhaus R, Reuter H: Activation of different pathways for calcium elevation by bradykinin and ATP in rat pheochromocytoma (PCI2) cells. Pfliigcrs Arch 1992; 420:213-218.
32. Gerwins P, Fredholm BB: ATP and its metabolite adenosine act syner-gistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line. J Biol Chem 1992; 267:16081-16087.
33. 2+ release in smooth muscle cells of the guinea pig taenia cae-ci. J Gen Physiol 1990;95:1103-1122.
34. 2. J Cell Biol 1993;121:91-99.
35. Strathmann M, Simon MI: G protein diversity: A distinct class of a subunits is present in vertebrates and invertebrates. Proc Natl Acad Sci USA 1990;87:9113-9117.