Molecular studies of the acute infection, latency and reactivation of equine herpesvirus-1 (EHV-1) in the mouse model

Virus Research

Volumn 40, Issue 1, 1996, Pages 33-45

  Baxi, M K ^a   Borchers, K ^b   Bartels, T ^b   Schellenbach, A ^b   Baxi, S ^a   Field, H J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Acute infection; Equine herpesvirus 1; Latency; Reactivation

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HERPES VIRUS; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; VIRUS INFECTION; VIRUS LATENCY; VIRUS REACTIVATION; VIRUS TRANSCRIPTION;

ANIMALIA; EQUIDAE; EQUINE HERPESVIRUS 1; HERPES; HERPESVIRIDAE; HERPESVIRUS 1; MURINAE;

EID: 0029863834     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-1702(95)01255-9     Document Type: Article

References (34)

1. Allen, G.P. and Bryans, J.T. (1986) Molecular epizootiology, pathogenesis and prophylaxis of equine herpesvirus-1 infections. Prog. Vet. Microbiol. Immunol. 2, 78-144.
2. Arthur, J., Efstathiou, S. and Simmons, A. (1993) Intranuclear foci containing low abundance herpes simplex virus latency-associated transcripts visualized by non-isotopic in situ hydridization. J. Gen. Virol. 74, 1363-1370.
3. Awan, A.R., Baxi, M.K. and Field, H.J. (1995) EHV-I induced abortion in mice and its relationship to stage of gestation. Res. Vet. Sci. 59, 139-145.
4. Awan, A.R., Chong, Y.-C. and Field, H.J. (1990) The pathogenesis of equine herpesvirus type 1 in the mouse: a new model for studying host responses to infection. J. Gen. Virol. 71, 1131-1140.
5. Azmi, M. and Field, H.J. (1993a) Cell-mediated antiviral response to equine herpesvirus type 1 demonstrated in a murine model by means of adoptive transfer of immune cells. J. Gen. Virol. 74, 275-280.
6. Azmi, M. and Field, H.J. (1993b) Interactions between equine herpesvirus type 1 and equine herpesvirus type 4: T cell responses in a murine model. J. Gen. Virol. 74, 2339-2345.
7. Ballagi-Paordany, A., Klingeborn, B., Flensburg, J. and Belak, S. (1990) Equine herpesvirus type 1: detection of viral DNA sequences in aborted fetuses with the polymerase chain reaction. Vet. Microbiol. 22, 373-381.
8. Baxi, M.K., Efsthatiou, S., Lawrence, G.L., Whalley, J.M., Slater, J.D. and Field, H.J. (1995) The detection of latency associated transcripts of equine herpesvirus 1 (EHV-1) in ganglionic neurons. J. Gen. Virol. 76, 3113-3118.
9. Borchers, K. and Slater, J. (1993) A nested PCR for the detection and differentiation of EHV-1 and EHV-4. J. Virol. Methods 45, 331-336.
10. Browning, G.F., Bulach, D.M., Ficorilli, N., Roy, E.A., Thorp, B.H. and Studdert, M.J. (1988) Latency of equine herpesvirus 4 (equine rhinopneumonitis virus). Vet. Rec. 123, 518-519.
11. Burrows, R. and Goodridge, D. (1984) Studies of persistent and latent equid herpesvirus-1 and herpesvirus-3 infections in the Pirbright pony herd. In: G. Wittman, R.M. Gaskell and H.-J. Rzhia (Eds), Latent Herpesvirus Infections in Veterinary Medicine, pp. 307-319. Martinus Nijhoff, The Hague.
12. Chowdhury, S.I., Kubin, G. and Ludwig, H. (1986) Equine herpesvirus Type 1 (EHV-1) induced abortions and paralysis in a Lipizzaner stud: a contribution to the classification of equine herpesviruses. Arch. Virol. 90, 273-288.
13. Csellner, H., Whalley, J.M. and Love, D.N. (1995) Equine herpesvirus 1 HVS25A isolated from an aborted foetus produces disease in Balb/c mice. Aust. Vet. J. 62, 68-69.
14. Ecob-Prince, M.S., Hassan, K., Denheen, M.T. and Preston, C.M. (1995) Expression of β-galactosidase in neurons of dorsal root ganglia which were latently infected with herpes simplex virus type 1. J. Gen. Virol. 76, 1527-1532.
15. Edington, N., Bridges, C.G. and Huckle, A. (1985) Experimental reactivation of equid herpesvirus 1 (EHV-1) follow ing administration of corticosteroids. Equine Vet. J. 17, 369-372.
16. Edington, N., Welch, H.M. and Griffiths, L. (1994) The prevalence of latent equid herpesvirus in the tissues of 40 abattoir horses. Equine Vet. J. 26, 140-142.
17. Field, H.J., Awan, A.R., De La Fuente, R. and Gibson, J.S. (1992a) Use of a novel murine model for the study of EHV-1 host responses, immunoprophylaxsis and chemotherapy. In: W. Plowright, P.D. Roosdale and J.F. Wade (Eds), Equine Infectious Diseases, pp. 263-268. R. and W. Publications, Newmarket.
18. Field, H.J., Awan, A.R. and De La Fuente, R. (1992b) Reinfection and reactivation of equine herpesvirus 1 in the mouse. Arch. Virol. 123, 409-419.
19. Gibson, J.S., Slater, J.D., Awan, A.R. and Field, H.J. (1992a) Pathogenesis of equine herpesvirus-1 in specific pathogen-free foals: primary and secondary infection and reactivation. Arch. Virol. 123, 351-366.
20. Gibson, J.S., Slater, J.D., Awan, A.R. and Field, H.J. (1992b) The pathogenicity of Ab4p, the sequenced strain of equine herpesvirus-1, in specific pathogen-free foals. Virology 189, 317-319.
21. Gibson, J.S., O'Neil, T., Thackray, A., Hannant, D. and Field, H.J. (1992c) Serological responses of specific pathogen-free foals to equine herpesvirus-1: primary and secondary infection and reactivation. Vet. Microbiol. 32, 199-232.
22. Hukkanen, V., Heino, P., Sears, A.E. and Roizman, B. (1990) Detection of herpes simplex virus latency-associated RNA in mouse trigeminal ganglia by in situ hybridization using nonradioactive digoxigenin-labelled DNA and RNA probes. Methods Mol. Cell. Biol. 2, 70-81.
23. Inazu, M., Tsuha, O., Kirishawa, R., Kawakami, Y. and Iwai, H. (1993) Equid herpesvirus 1 infections in mice. J. Vet. Med. Sci. 51, 119-121.
24. Kydd, J.H., Smith, K.C., Hannant, D., Livesay, G.J. and Mumford, J.D. (1994) Distribution of equine herpesvirus-1 (EHV-1) in the respiratory tract of ponies: implications for vaccination strategies. Equine Vet. J. 26, 466-469.
25. Ludwig, H., Rudolph, R., Chowdhury, S.I., Van Den Bossche, G., Wintzer, H.J. and Krauser, K. (1987) Equine herpesvirus type 1 (EHV-1) Infektion beim Pferh: neurologische Symptomatik bei einer Warmblutstute mit akutem todlichen Verlauf. Molekulare Charakterisierung des Gehirnisolates und pathologische korrekte. Berl. Munch. Tierarztl Wschr. 100, 147-152.
26. Mehta, A., Maggioncalda, T., Bagasra, O., Thikkavarapu, S., Saikumari, P., Valyi-Nagi, T., Fraser, N.W. and Block, T.M. (1995) In situ DNA PCR and RNA hybridization detection of herpes virus simplex sequences in trigeminal ganglia of latently infected mice. Virology 206, 633-640.
27. Patel, J.R., Edington, N. and Mumford, J.A. (1982) Variation in cellular tropism between isolates of equine herpesvirus-1 in foals. Arch. Virol. 74, 41-51.
28. Ramakrishnan, R., Levine, M. and Fink, D.J. (1994) PCR-based analysis of herpes simplex virus type 1 latency in the rat trigeminal ganglion established with a ribonucleotide reductase-deficient mutant. J. Virol. 68, 7083-7091.
29. Sharma, P.C., Cullinane, A.A., Onions, D.E. and Nicolson, L. (1992) Diagnosis of equid herpesvirus-1 and -4 by polymerase chain reaction. Equine Vet. J. 24, 20-25.
30. Slater, J.D., Borchers, K., Thackary, A.M. and Field, H.J. (1994) The trigeminal ganglion is a location for equine herpesvirus 1 latency and reactivation in the horse. J. Gen. Virol. 75, 2007-2016.
31. Slater, J.D., Gibson, J.S. and Field, H.J. (1993) Pathogenicity of a thymidine kinase-deficient mutant of equine herpesvirus type 1 in mice and specific pathogen-free foals. J. Gen. Virol. 74, 819-828.
32. Smith, K.C., Whitwell, K.E., Binns, M.M., Dolby, C.A., Hannant, D. and Mumford, J.A. (1992) Abortion of virologically negative foetuses following experimental challenge of pregnant pony mares with equid herpesvirus 1. Equine Vet. J. 24, 256-259.
33. Telford, E.A.R., Watson, M.S., McBride, K. and Davison, A.J. (1992) The DNA sequence of equine herpesvirus-1. Virology 189, 304-316.
34. Welch, H.M., Bridges, C.G., Lyon, A.M., Griffiths, L. and Edington, N. (1992) Latent equid herpesvirus 1 and 4: detection and distribution using the polymerase chain reaction and co-cultivation from lymphoid tissues. J. Gen. Virol. 73, 261-268.