Hepatic drug-metabolizing activities in rats after 14 days of oral administration of the human immunodeficiency virus-type 1 protease inhibitor ritonavir (ABT-538)

Drug Metabolism and Disposition

Volumn 24, Issue 5, 1996, Pages 615-617

  Kumar, Gondi N ^a   Grabowski, Brian ^a   Lee, Ronald ^a   Denissen, Jon F ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BENZPHETAMINE; CHLORZOXAZONE; ETHOXYRESORUFIN; GLUCURONOSYLTRANSFERASE; ISOENZYME; PENTOXYRESORUFIN; PHENOBARBITAL; PROTEINASE INHIBITOR; RITONAVIR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG METABOLISM; DRUG TRANSFORMATION; ENZYME INDUCTION; ENZYME SUBSTRATE; FEMALE; HUMAN IMMUNODEFICIENCY VIRUS 1; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER MICROSOME; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; ETHINYL ESTRADIOL; FEMALE; GLUCURONOSYLTRANSFERASE; HIV PROTEASE INHIBITORS; MALE; MICROSOMES, LIVER; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; RITONAVIR;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0029863812     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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