The herpes simplex virus type 2 strain HG52 RL1 gene contains a 154 bp intron as predicted from sequence analysis

Journal of General Virology

Volumn 77, Issue 3, 1996, Pages 481-484

  Harland, June E ^a   Bdour, Salwa ^a   Brown, S Moira ^a   MacLean, Alasdair R ^a,b  

^a INSTITUTE OF VIROLOGY   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; POLYADENYLATED RNA;

ARTICLE; GENE SEQUENCE; HERPES SIMPLEX VIRUS 2; INTRON; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOP CODON; VIRUS GENE; VIRUS VIRULENCE;

HERPES; HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 2;

EID: 0029863797     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-77-3-481     Document Type: Article

References (12)

1. CHOMCZYNSKI, P. & SACCHI, N (1987). Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Analytical Biochemistry 162, 156-159
2. CHOU, J & ROIZMAN, B. (1986). The terminal 'a' sequence of the herpes simplex virus genome contains the promoter of a gene located in the repeat sequences of the L component. Journal of Virology 57, 629-637.
3. CHOU, J. & ROIZMAN, B. (1990). The herpes simplex virus 1 gene for ICP34.5, which maps in the inverted repeats, is conserved in several limited-passage isolates but not in strain 17 syn. Journal of Virology 64, 1014-1020.
4. DOLAN, A., MCKIE, E., MACLEAN, A. R. & MCGEOCH, D. J. (1992). Status of the ICP34.5 gene in herpes simplex virus type 1 strain 17. Journal of General Virology 73, 971-973.
5. LANGUNOFF, M. & ROIZMAN, B. (1994). Expression of a herpes simplex virus open reading frame antisense to the γ34.5 gene and transcribed by an RNA 3′ coterminal with the unspliced latency-associated transcript. Journal of Virology 68, 6021-6028.
6. MC-GEOCH, D. J., CUNNINGHAM, C., MCINTYRE, G & DOLAN, A. (1991). Comparative sequence analysis of the long repeat region and adjoining parts of the long unique region in the genomes of herpes simplex viruses types 1 and 2. Journal of General Virology 72, 3057-3075.
7. + between immediate early gene 1 and the 'a' sequence. Journal of General Virology 72, 631-639.
8. SANGER, F., NICKLEN, S. & COULSON, A. R. (1977). DNA sequencing with chain-terminating inhibitors. Proceedings of the National Academy of Sciences, USA 74, 5463-5467.
9. L between 0 to 0.02 and 0.81 to 0.83 map units is non-neurovirulent for mice. Journal of General Virology 70, 705-716.
10. TAHA, M. Y., CLEMENTS, G. B. & BROWN, S. M. (1989b). The herpes simplex virus type 2 (HG52) variant JH2604 has a 1488 bp deletion which eliminates neurovirulence in mice. Journal of General Virology 70, 3073-3078.
11. THOMPSON, R. L., WAGNER, E. K. & STEVENS, J. G. (1983). Physical location of a herpes simplex virus type 1 function(s) specifically involved in HSV neurovirulence. Virology 131, 180-192.
12. THOMPSON, R. L., ROGERS, S. K. & ZERHUSEN, M. A (1989). Herpes simplex virus neuro virulence and productive infection of neural cells is associated with a function which maps between 0.82 and 0.832 map units on the HSV-1 genome Virology 172, 435-450.