The tumor association of a trisaccharide epitope: Specificity of antiserum developed to galactose ß1→3 N-acetyl glucosamine β1→3 galactose

Immunological Investigations

Volumn 25, Issue 3, 1996, Pages 253-266

  Diakun, Kate Rittenhouse ^a   Vargas, Farida ^a   Tamburlin, Judith ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISERUM; EPITOPE; IMMUNOGLOBULIN G ANTIBODY; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; TRISACCHARIDE; TUMOR ANTIGEN;

ANTIBODY SPECIFICITY; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; COLON CARCINOMA; CONTROLLED STUDY; ENDOMETRIUM CARCINOMA; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGENICITY; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; UTERINE CERVIX CARCINOMA;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEOPLASM; ANTIBODY SPECIFICITY; ANTIGENS, NEOPLASM; CARBOHYDRATE SEQUENCE; CATTLE; ENDOMETRIAL NEOPLASMS; EPITOPES; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MOLECULAR SEQUENCE DATA; OLIGOSACCHARIDES; RABBITS; TISSUE DISTRIBUTION; TRISACCHARIDES; TUMOR CELLS, CULTURED;

EID: 0029863661     PISSN: 08820139     EISSN: None     Source Type: Journal    
DOI: 10.3109/08820139609059307     Document Type: Article

References (27)

1. Nozawa, S., Narisawa, S., Kojima, K., Sakayori, M., Iizuka, R., Mochizuki, H., Yamauchi, T., Iwamori, M., and Nagai, Y. Human monoclonal antibody (HMST-1) against lacto-series type 1 chain and expression of the chain in uterine endometrial cancers. Cancer Res., 49: 6401-6406, 1989.
2. Feizi, T., and Childs, R. A. Carbohydrate structures of glycoproteins and glycolipids as differentiation antigens, tumour-associated antigens and components of receptor systems. TIBS, : 24-29, Jan. 1985.
3. Dennis, J. W. N-linked oligosaccharide processing and tumor cell biology. Seminars in Cancer Biol., 2: 411-420, 1991.
4. Singhal, A.K. Histo-blood group antigens in cancer. Sem. Cancer Biol. 2: 379-388, 1991.
5. McBroom, C.R., Samenen, C. and Goldstein, I. Carbohydrate antigens: coupling of carbohydrates to proteins by a diazonium and phenylisothiocyanate reaction. In: Methods in Enzymology. Vol XXVII. C. Hirs and S. Timasheff, eds., Academic Press, New York, p. 212, 1972. Immunol. Invest, 20:21-32, 1991.
6. McBroom, C.R., Samenen, C. and Goldstein, I. Carbohydrate antigens: coupling of carbohydrates to proteins by a diazonium and phenylisothiocyanate reaction. In: Methods in Enzymology. Vol XXVII. C. Hirs and S. Timasheff, eds., Academic Press, New York, p. 212, 1972. Immunol. Invest, 20:21-32, 1991.
7. Diakun, K.R. and Matta, K.L. Synthetic antigens as immunogens: Part III Specificity Analysis of an anti-anti-idiotypic antibody to a carbohydrate tumor-associated antigen. J. Immunol. 142:2037-2040, 1989.
8. Diakun, K.R., Yazawa, S., Valenzuela, L., Abbas, S.A. and Matta, K.L. Synthetic antigens as immunogens: Part I. The combining site specificities of antibodies formed in rabbits to synthetic disaccharide α-LFuc(1→3)-D-Gal. Immunol. Invest. 16:1-11, 1987.
9. Matta, K.L., Piscorz, C.F., Abbas, S.A. and Diakun, K.R. Synthetic antigens as immunogens: Part IV. Specificity of antisera developed to Galβ1-3(GlcNAcβ1-6)GalNAc and GlcNAcβ1-6GalNAc. Immunol. Invest. 20:525-537, 1991.
10. Handley, D.J., Matta, K.L., Piver, M.S. and Diakun, K.R. Antigenic studies on an enzymatically sialylated carbohydrate: NeuAc(α2-3)Galβ1-3)[GlcNAc(β1-6]GalNAc. Immunol. Invest. 20:21-32, 1991.
11. Lowry, O.H., Rusebrough, N.J., Farr, A.L. and Randall, R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193:265-275, 1951.
12. Dubois, M., Gilles, K.A., Hamilton, J.K., Rebers, P.A. and Smith, F. Colorimetric method for determination of sugars and other related substances. Analyt. Chem. 28:350-356, 1956.
13. Vaitukaitis, J., Robbins, B., Nieschlag, E., and Ross, G.T. A Method for Producing Specific Antisera with Small Doses of Immunogen. J. Clin. Endocrinol., 33: 988-991, 1971.
14. Engvall, E. and Perlman, P. Enzyme-linked immunosorbant assay, ELISA III. Quantitation of specific antibodies by enzyme labelled anti-immunoglobulin in antigencoated tubes. J. Immunol. 709:129, 1972.
15. Terashima, M., Kato, K., Osawa, T., Chiba, T., and Tejima, S. An antibody to lacto-N-biose I. Carbohydrate Res., 110: 345-350, 1982.
16. Shiozawa Holmes, E. H., and Greene, T. G. Characterization of two monoclonal antibodies specific for lacto-series type 1 chain Galβ1 → 3GlcNAc-terminal structures. Arch. Biochem. Biophys. 277: 181-188, 1990.
17. b, I and i Active Glycoproteins Purified From Human Ovarian Cyst Fluid, in The Molecular Immunology of Complex Carbohydrates ed. Wu, A.M. and Adams, L. G. in Adv. in Exp. Med and Biology vol. 228. ed. Back, N., Katchalski-Katzir, E., Kritchevsky, Lajtha, A., Paoletti, R., 1988.
18. Inoue, M., Sasgawa, T., Saito, J., Shimizu, H., Ueda, G., Tanizawa, O., and Nakayama, M. Expression of blood group antigens A, B, H, Lewis-a, and Lewis-b in fetal, normal, and malignant tissues of the uterine endometrium. Cancer, 60: 2985-2993, 1987.
19. Nozawa, S., Sakayori, M., Ohta, K., Iizuka, R., Mochizuki, H., Soma, M., Fujimoto, J-I., Hata, J-I., Iwamori, M., and Nagai, Y. A monoclonal antibody (MSN-1) against a newly established uterine endometrial cancer cell line (SNG-II) and its application to immunohistochemistry and flow cytometry. Amer. J. Obstet. Gynec., 161: 1079-1086, 1989.
20. 4) of human colonic adenocarcinoma and the monoclonal antibody (FH7) defining this structure. J. Biol. Chem., 261: 5487-5495, 1986.
21. Magnani, J. L., Nilsson, B., Brockhaus, M., Zopf, D., Steplewski, Z., Koprowski, H., and Ginsburg, V. A monoclonal antibody-defined antigen associated with gastrointestinal cancer is a ganglioside containing sialylated lacto-N-fucopentaose II. J. Biol. Chem., 257: 14365-14369, 1982.
22. 6) as human tumor-associated antigen. J. Biol. Chem., 266: 8439-8446, 1991.
23. Andrews, P. W., Gönczöl, E., Fenderson, B. A., Holmes, E. H., O'Malley, G., Hakomori, S-I., and Plotkin, S. Human cytomegalovirus induces stage-specific embryonic antigen 1 in differentiating human teratocarcinoma cells and fibroblasts. J. Exp. Med., 169: 1347-1359, 1989.
24. Marcus, D. M., Gilbert, S., Sekine, M., and Suzuki, A. Monoclonal antibodies that bind to galactosylgloboside (SSEA-3 antigen). Arch. Biochem. Biophys., 262: 620-625, 1988.
25. Holmes, E. H. Characterization and membrane organization of β1 → 3- and β1 → 4-galactosyltransferases from human colonic adenocarcinma cell lines colo 205 and SW403: Basis for preferential synthesis of type 2 chain lacto-series carbohydrate structures. Arch. Biochem. Biophys. 270: 630-646, 1989.
26. Fukushi, Y., Hakomori, S-I., Nudelman, E., and Cochran, N. Novel fucolipids accumulating in human adenocarcinoma. II. Selective isolation of hybridoma antibodies that differentially recognize mono-, di-, and trifucosylated type 2 chain. J. Biol. Chem., 259: 4681-4685, 1984.
27. Hakomori, S-I. Structures and organization of cell surface glycolipids dependency on cell growth and malignant transformation. Biochim. Biophys. Acta 417: 55-89, 1975.