Molecular organization and alternative splicing in zipper, the gene that encodes the Drosophila non-muscle myosin II heavy chain

Journal of Molecular Biology

Volumn 255, Issue 1, 1996, Pages 98-109

  Mansfield, S Gary ^a,b   Al Shirawi, Dana Y ^a   Ketchum, Andrew S ^b   Newbern, E Claire ^a   Kiehart, Daniel P ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

Genomic DNA; Mutations; Myosin isoforms; Promoter region; Zipper

Indexed keywords

ISOPROTEIN; MYOSIN HEAVY CHAIN;

ALTERNATIVE RNA SPLICING; ARTICLE; DROSOPHILA; EXON; GENE; GENE MUTATION; MOLECULAR BIOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION;

EID: 0029863246     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0009     Document Type: Article

References (53)

1. Arkhipova, I. R. (1995). Promoter elements in Drosophila melanogaster revealed by sequence analysis. Genetics, 139, 1359-1369.
2. Babij, P., Kelly C. & Periasamy M. (1991). Characterization of a mammalian smooth muscle myosin heavy-chain gene: complete nucleotide and protein coding sequence and analysis of the 5′ end of the gene. Proc. Natl Acad. Sci. USA, 88, 10676-10680.
3. Beverly, S. M. & Wilson, A. C. (1984). Molecular evolution in Drosophila and the higher diptera. II. A time scale for fly evolution. J. Mol. Evol. 21, 1-13.
4. Bhatia-Dey N., Adelstein, R. S. & Dawid, I. B. (1993). Cloning of the cDNA encoding a myosin heavy chain B isoform of Xenopus nonmuscle myosin with an insert in the head region. Proc. Natl Acad. Sci. USA, 90, 2856-2859.
5. Birnstiel, M. L., Busslinger, M. & Strub, K. (1985). Transcription termination and 3′ processing: the end is in site! Cell, 41, 349-359.
6. Breitbart, R. E., Andreadis, A. & Nadal-Ginard, B. (1987). Alternative splicing: a ubiquitous mechanism for the generation of multiple protein isoforms from single genes. Annu. Rev. Biochem. 56, 467-495.
7. Côté, S., Preiss, A., Haller, J., Schuh, R., Kienlin, A., Seifert, E. & Jäckle, H. (1987). The gooseberry-zipper region of Drosophila: five genes encode different spatially restricted transcripts in the embryo. EMBO J. 6, 2793-2801.
8. Dynan, W. S. (1986). Promotors for housekeeping genes. Trends Genet. 2, 196-197.
9. George, E. L., Ober, M. B. & Emerson, C. P., Jr (1989). Functional domains of the Drosophila melanogaster muscle myosin heavy-chain gene are encoded by alternatively spliced exons. Mol. Cell Biol. 9, 2957-2974.
10. Hammer, J. A., Bowers, B., Paterson, B. M. & Korn, E. D. (1987). Complete nucleotide sequence and deduced polypeptide sequence of a nonmuscle myosin heavy chain gene from Acanthamoeba: evidence of a hinge in the rodlike tail. J. Cell Biol. 105, 913-925.
11. Harlow, E. & Lane, D. (1988). Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
12. Harrington, W. F. & Rodgers, M. E. (1984). Myosin. Annu. Rev. Biochem. 53, 35-73.
13. Horowitz, D. S. & Krainer, A. R. (1994). Mechanisms for selecting 5′ splice sites in mammalian pre-mRNA splicing. Trends Genet. 10, 100-106.
14. Karess, R. E., Chang X. J., Edwards K. A., Kulkarni, S., Aguilera, I. & Kiehart, D. P. (1991). The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila. Cell, 65, 1177-1189.
15. Karn, J., Brenner, S. & Barnett, L. (1983). Protein structural domains in the Caenorhabiditis elegans unc-54 myosin heavy chain gene are not separated by introns. Proc. Natl Acad. Sci. USA, 80, 4253-4257.
16. Kawamoto, S. (1994). Evidence for an internal regulatory region in a human nonmuscle myosin heavy chain gene. J. Biol. Chem. 269, 15101-15110.
17. Kawamoto, S. & Adelstein, R. S. (1991). Chicken nonmuscle myosin heavy chains: differential expression of two mRNAs and evidence for two different polypeptides. J. Cell Biol. Chem. 264, 2258-2265.
18. Kelley C. A., Takahashi, M., Yu, Ju, H. & Adelstein, R. S. (1993). An insert of seven amino acids confers functional differences between smooth muscle myosins from the intestines and vasculature. J. Biol. Chem. 15, 12848-12854.
19. cdc2 kinase during meiosis. J. Biol. Chem. 270, 1395-1401.
20. Ketchum, A. S., Stewart, C. T., Stewart, M. & Kiehart, D. P. (1990). Complete sequence of the Drosophila non-muscle myosin heavy chain transcript: conserved sequences in the myosin tail and differential splicing in the 5′ untranslated sequence. Proc. Natl Acad. Sci. USA, 87, 6316-6320.
21. Kiehart, D. P. & Feghali, R. (1986). Cytoplasmic myosin from Drosophila melanogaster. J. Cell Biol. 103, 1517-1525.
22. Kiehart, D. P., Lutz, M. S., Chan, D., Ketchum, A. S., Laymon, R. A., Nguyen, B. & Goldstein, L. S. B. (1989). Identification of the gene for fly nonmuscle myosin heavy chain: Drosophila myosin heavy chains are encoded by a gene family. EMBO J. 8, 913-922.
23. Kiehart, D. P., Ketchum, A., Young, P., Lutz, D., Alfenito, M. R., Chang, X.-j., Awobuluyi, M., Pesacreta, T. C., Inoué, S., Stewart, C. T. & Chen, T.-l. (1990). Contractile proteins in Drosophila development. Ann. N.Y. Acad. Sci. 582, 233-251.
24. Kingston, R. E. (1989). In Current Protocols in Molecular Biology (Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith. J. A. & Struhl, K., eds), pp. 4.8.1-4.8.3. Wiley New York.
25. McLauchlan, J., Gaffney D., Whitton, J. L. & Clements, J. B. (1985). The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3′ termini. Nucl. Acids Res. 13, 1347-1368.
26. Mount, S. M., Burks, C., Hertz, G., Stormo, G. D., White, O. & Fields, C. (1992). Splicing signals in Drosophila: intron size, information content, and consensus sequences. Nucl. Acids Res. 20, 4255-4262.
27. Moussavi, R. S., Kelley, C. A. & Adelstein, R. S. (1993). Phosphorylation of vertebrate nonmuscle and smooth muscle myosin heavy chains and light chains. Mol. Cell. Biochem. 127/128, 219-227.
28. Nigg, E. A. (1991). The substrates of the cdc2 kinase. Sem. Cell Biol. 2, 261-270.
29. Nüsslein-Volhard, C., Wieschaus, E. & Kluding, H. (1984). Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. I. Zygotic loci on the second chromosome. Wilhelm Roux's Arch. Dev. Biol. 193, 267-282.
30. Rayment, I., Rypniewski, W. R., Schmidt-Bäse, K., Smith, R., Tomchick, D. R., Benning, M. M., Winkelmann, D. A., Wesenberg, G. & Holden, H. M. (1993). Three-dimensional structure of myosin subfragment-I: a molecular motor. Science, 261, 50-65.
31. Richardson, D. C. & Richardson, J. S. (1992). The kinemage: a tool for scientific research. Protein Sci. 1, 3-9.
32. Richardson, D. C. & Richardson. J. S. (1994). Kinemages -simple macromolecular graphics for interactive teaching and publication. Trends Biochem. Sci. 19, 135-138.
33. Sanger, F., Nicklen, S. & Coulsen, A. R. (1977). DNA sequencing with chain-terminating inhibitors. Proc. Natl Acad. Sci. USA, 74, 5463-5467.
34. Seely O., Jr, Feng, D.-F., Smith, D. W., Sulzbach, D. & Doolittle, R. F. (1990). Construction of a facsimile data set for large genome sequence analysis. Genomics, 8, 71-82.
35. Senapathy, P., Shapiro, M. B. & Harris, N. L. (1990). Splice junctions, branch point sites and exons: sequence statistics, identification and application to Genome Project. In Methods Enzymology (Doolittle, R. F., ed.), vol. 183, pp. 252-278. Academic Press, Inc., Berkeley.
36. Shohet, R. V., Conti, M. A., Kawamoto, S., Preston, Y. A., Brill, D. A. & Adelstein, R. S. (1989). Cloning of the cDNA encoding the myosin heavy chain of a vertebrate cellular myosin. Proc. Natl. Acad. Sci. USA, 86, 7726-7730.
37. Simons, M., Wang, M., McBride, O. W. & Kawamoto, S. (1991). Human nonmuscle myosin heavy chains are encoded by two genes located in different chromosomes. Circ. Res. 69, 530-539.
38. Solovyev, V. V., Salamov, A. A. & Lawrence, C. B. (1994). Predicting internal exons by oligonucleotide composition and discriminant analysis of spliceable open reading frames. Nucl. Acids Res. 22, 5156-5163.
39. Strehler, E. E., Mahdavi, V., Periasamy M. & Nadal-Ginard, B. (1985). Intron positions are conserved in the 5′ end region of myosin heavy-chain genes. J. Biol. Chem. 260, 468-471.
40. Strehler, E. E., Strehler-Page, M.-A., Perriard, J. C., Perisamy M. & Nadal-Ginard, B. (1986). Complete nucleotide and encoded amino acid sequence of a mammalian myosin heavy chain gene. Evidence against intron-dependent evolution of the rod. J. Mol. Biol. 190, 291-317.
41. Sun, W. & Chantler, P. D. (1992). Cloning of the cDNA encoding a neuronal myosin heavy chain from mammalian brain and its differential expression within the central nervous system. J. Mol. Biol. 224, 1185-1193.
42. Takahashi, M., Kawamoto, S. & Adelstein, R. S. (1992). Evidence for inserted sequences in the head region of nonmuscle myosin specific to the nervous system. J. Biol. Chem. 267, 17864-17871.
43. Uyeda, T. Q. P., Ruppel, K. M. & Spudich, J. A. (1994). Enzymatic activities correlate with chimaeric substitutions at the actin-binding interface of myosin. Nature, 368, 567-569.
44. Wahle, E. & Keller, W. (1992). The biochemistry of 3′-end cleavage and polyadenylation of messenger RNA. Annu. Rev. Biochem. 61, 419-440.
45. Warrick, H. M. & Spudich, J. A. (1987). Myosin structure and function in cell motility Annu. Rev. Cell Biol. 3, 379-421.
46. Warrick, H. M., De Lozanne, A., Leinwand, L. A. & Spudich, J. A. (1986). Conserved protein domains in a myosin heavy chain gene from Dictyostelium discoideum. Proc. Natl Acad. Sci. USA, 83, 9433-9437.
47. Watts, F. Z., Shiels, G. & Orr, E. (1987). The yeast MYO1 gene encoding a myosin-like protein required for cell division. EMBO J. 6, 3499-3505.
48. Williams, T. & Tijan, R. (1991). Analysis of the DNA-binding & activation properties of the human transcription factor AP-2. Genes Dev. 5, 670-682.
49. Xie, X., Harrison, D. H., Schlichting, I., Sweet, R. M., Kalabokis, V. N., Szent-Györgyi, A. G. & Cohen, C. (1994). Structure of the regulatory domain of scallop myosin at 2.8 Å resolution. Nature, 368, 306-312.
50. Yanagisawa, M., Hamada, Y., Katsuragawa, Y., Imamura, M., Mikawa, T. & Masaki, T. (1987). Complete primary structure of vertebrate smooth muscle myosin heavy chain deduced from its complementary DNA sequence. Implications on topography and function of myosin. J. Mol. Biol. 198, 143-157.
51. Young, P. E., Pesacreta, T. C. & Kiehart, D. P. (1991). Dynamic hanges in the distribution of cytoplasmic myosin during Drosophila embryogenesis. Development, 111, 1-14.
52. Young, P. E., Richman, A. M., Ketchum, A. S. & Kiehart, D. P. (1993). Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function. Genes Dev. 7, 29-41.
53. Zhao, D., Côté, S., Jähnig, F., Haller, J. & Jäckle, H. (1988). Zipper encodes a putative integral membrane protein required for normal axon patterning during Drosophila neurogenesis. EMBOJ. 7, 1115-1119.