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Volumn 44, Issue 2, 1996, Pages 97-105

Agonist self-inhibitory binding site of the nicotinic acetylcholine receptor

Author keywords

agonist self inhibitory binding site; localization of binding sites; luminal and nonluminal binding sites; nicotinic acetylcholine receptor; noncompetitive inhibitors

Indexed keywords

ETHIDIUM; ION CHANNEL; MEPACRINE; MUSCARINIC M2 RECEPTOR; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; PROCAINE;

EID: 0029863212     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19960415)44:2<97::AID-JNR1>3.0.CO;2-B     Document Type: Short Survey
Times cited : (23)

References (72)
  • 1
    • 0017755172 scopus 로고
    • Voltage jump analysis of procaine action at frog end-plate
    • Adams PR (1977): Voltage jump analysis of procaine action at frog end-plate. J Physiol 268:291-318.
    • (1977) J Physiol , vol.268 , pp. 291-318
    • Adams, P.R.1
  • 2
    • 0018911333 scopus 로고
    • Quinacrine (mepacrine) action at frog endplate
    • Adams PR, Feltz A (1980a): Quinacrine (mepacrine) action at frog endplate. J Physiol 306:261-281.
    • (1980) J Physiol , vol.306 , pp. 261-281
    • Adams, P.R.1    Feltz, A.2
  • 3
    • 0018911330 scopus 로고
    • Endplate channel opening and the kinetics of quinacrine blocks
    • Adams PR, Feltz A (1980b): Endplate channel opening and the kinetics of quinacrine blocks. J Physiol 306:283-306.
    • (1980) J Physiol , vol.306 , pp. 283-306
    • Adams, P.R.1    Feltz, A.2
  • 4
    • 0018147898 scopus 로고
    • Decamethonium both opens and blocks endplate channels
    • Adams PR, Sakmann B (1978): Decamethonium both opens and blocks endplate channels. Proc Natl Acad Sci USA 75:2994-2998.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 2994-2998
    • Adams, P.R.1    Sakmann, B.2
  • 5
    • 0026485739 scopus 로고
    • Acetylcholine receptor channel structure probed in cysteine-substitution mutants
    • Akabas MH, Stauffer DA, Xu M, Karlin A (1992): Acetylcholine receptor channel structure probed in cysteine-substitution mutants. Science 258:307-310.
    • (1992) Science , vol.258 , pp. 307-310
    • Akabas, M.H.1    Stauffer, D.A.2    Xu, M.3    Karlin, A.4
  • 6
    • 0027987062 scopus 로고
    • Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the a subunit
    • Akabas MH, Kaufmann C, Archdeacon P, Karlin A (1994): Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the a subunit. Neuron 13:919-927.
    • (1994) Neuron , vol.13 , pp. 919-927
    • Akabas, M.H.1    Kaufmann, C.2    Archdeacon, P.3    Karlin, A.4
  • 8
    • 0029382882 scopus 로고
    • Agonist-induced displacement of quinacrine from its binding site on the nicotinic acetylcholine receptor: Plausible agonist membrane partitioning mechanism
    • Arias HR (1995): Agonist-induced displacement of quinacrine from its binding site on the nicotinic acetylcholine receptor: Plausible agonist membrane partitioning mechanism. Mol Membr Biol 12:339-347.
    • (1995) Mol Membr Biol , vol.12 , pp. 339-347
    • Arias, H.R.1
  • 9
    • 0029922297 scopus 로고    scopus 로고
    • Luminal and non-luminal non-competitive inhibitor binding sites on the nicotinic acetylcholine receptor
    • Arias HR (1996): Luminal and non-luminal non-competitive inhibitor binding sites on the nicotinic acetylcholine receptor (review). Mol Membr Biol 13:1-17.
    • (1996) Mol Membr Biol , vol.13 , pp. 1-17
    • Arias, H.R.1
  • 10
    • 0028965956 scopus 로고
    • Differential agonist-induced displacement of quinacrine and ethidium from their respective histrionicotoxin-sensitive binding sites on the Torpedo acetylcholine receptor
    • Arias HR, Johnson DA (1995): Differential agonist-induced displacement of quinacrine and ethidium from their respective histrionicotoxin-sensitive binding sites on the Torpedo acetylcholine receptor. Biochemistry 34:1589-1595.
    • (1995) Biochemistry , vol.34 , pp. 1589-1595
    • Arias, H.R.1    Johnson, D.A.2
  • 11
    • 0027413304 scopus 로고
    • Transverse localization of the quinacrine binding site on the Torpedo acetylcholine receptor
    • Arias HR, Valenzuela CF, Johnson DA (1993a): Transverse localization of the quinacrine binding site on the Torpedo acetylcholine receptor. J Biol Chem 268:6348-6355.
    • (1993) J Biol Chem , vol.268 , pp. 6348-6355
    • Arias, H.R.1    Valenzuela, C.F.2    Johnson, D.A.3
  • 12
    • 0027230908 scopus 로고
    • Quinacrine and ethidium bind to different loci on the Torpedo acetylcholine receptor
    • Arias HR, Valenzuela CF, Johnson DA (1993b): Quinacrine and ethidium bind to different loci on the Torpedo acetylcholine receptor. Biochemistry 32.6237-6242.
    • (1993) Biochemistry , vol.32 , pp. 6237-6242
    • Arias, H.R.1    Valenzuela, C.F.2    Johnson, D.A.3
  • 13
    • 0025350418 scopus 로고
    • Importance of the membrane in ligand-receptor interactions
    • Behling RW, Jelinski LW (1990): Importance of the membrane in ligand-receptor interactions. Biochem Pharmacol 40:49-54.
    • (1990) Biochem Pharmacol , vol.40 , pp. 49-54
    • Behling, R.W.1    Jelinski, L.W.2
  • 14
    • 0027378194 scopus 로고
    • Voltage dependencies of the effects of chlorpromazine on the nicotinic receptor channel from mouse muscle cell line Sol 8
    • Benoit P, Changeux J-P (1993): Voltage dependencies of the effects of chlorpromazine on the nicotinic receptor channel from mouse muscle cell line Sol 8. Neurosci Lett 160:81-84.
    • (1993) Neurosci Lett , vol.160 , pp. 81-84
    • Benoit, P.1    Changeux, J.-P.2
  • 15
    • 0029006150 scopus 로고
    • Nicotinic receptor: An allosteric protein specialized for intercellular communication
    • Bertrand D, Changeux J-P (1995): Nicotinic receptor: An allosteric protein specialized for intercellular communication. Semin Neurosci 7:75-90.
    • (1995) Semin Neurosci , vol.7 , pp. 75-90
    • Bertrand, D.1    Changeux, J.-P.2
  • 16
    • 0025236914 scopus 로고
    • Activation and blocking of neuronal nicotinic acetylcholine receptor reconstituted in Xenopus oocytes
    • Bertrand D, Ballivet M, Rungger D (1990): Activation and blocking of neuronal nicotinic acetylcholine receptor reconstituted in Xenopus oocytes. Proc Natl Acad Sci USA 87:1993-1997.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1993-1997
    • Bertrand, D.1    Ballivet, M.2    Rungger, D.3
  • 17
    • 0028585937 scopus 로고
    • Agonist-induced photoincorporation of a p-benzoylphenylala-nine derivative of substance P into membrane-spanning region 2 of the Torpedo nicotinic acetylcholine receptor 8 subunit
    • Blanton MP, Li YM, Stimson ER, Maggio JE, Cohen JB (1994): Agonist-induced photoincorporation of a p-benzoylphenylala-nine derivative of substance P into membrane-spanning region 2 of the Torpedo nicotinic acetylcholine receptor 8 subunit. Mol Pharmacol 46:1048-1055
    • (1994) Mol Pharmacol , vol.46 , pp. 1048-1055
    • Blanton, M.P.1    Li, Y.M.2    Stimson, E.R.3    Maggio, J.E.4    Cohen, J.B.5
  • 18
    • 0027265417 scopus 로고
    • Channel blocking properties of a series of nicotinic cholinergic agonists
    • Carter AA, Oswald RE (1993): Channel blocking properties of a series of nicotinic cholinergic agonists. Biophys J 65:840-851.
    • (1993) Biophys J , vol.65 , pp. 840-851
    • Carter, A.A.1    Oswald, R.E.2
  • 19
    • 0022558294 scopus 로고
    • Effects of chlorpromazine and phencyclidine on mouse C2 acetylcholine receptor kinetics
    • Changeux J-P, Pinset C, Ribera AB (1986): Effects of chlorpromazine and phencyclidine on mouse C2 acetylcholine receptor kinetics. J Physiol 378:497-513.
    • (1986) J Physiol , vol.378 , pp. 497-513
    • Changeux, J.-P.1    Pinset, C.2    Ribera, A.B.3
  • 21
    • 0026773023 scopus 로고
    • Pharmacological and kinetic properties of α4β2 neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes
    • Charnet P, Labarca C, Cohen BN, Davidson N, Lester HA, Pilar G (1992): Pharmacological and kinetic properties of α4β2 neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. J Physiol 450:375-394.
    • (1992) J Physiol , vol.450 , pp. 375-394
    • Charnet, P.1    Labarca, C.2    Cohen, B.N.3    Davidson, N.4    Lester, H.A.5    Pilar, G.6
  • 22
    • 0027051415 scopus 로고
    • Photoactivatable agonist of the nicotinic acetylcholine receptor: Potential probe to characterize the structural transitions of the acetylcholine binding site in different states of the receptor
    • Chatrenet B, Kotzyba-Hibert F, Mulle C, Changeux J-P, Goeldner MP, Hirth C (1992): Photoactivatable agonist of the nicotinic acetylcholine receptor: Potential probe to characterize the structural transitions of the acetylcholine binding site in different states of the receptor. Mol Pharmacol 41:1100-1106.
    • (1992) Mol Pharmacol , vol.41 , pp. 1100-1106
    • Chatrenet, B.1    Kotzyba-Hibert, F.2    Mulle, C.3    Changeux, J.-P.4    Goeldner, M.P.5    Hirth, C.6
  • 23
    • 0023856335 scopus 로고
    • Activation of ion channels in the frog end-plate by high concentrations of acetylcholine
    • Colquhoun D, Ogden DC (1988): Activation of ion channels in the frog end-plate by high concentrations of acetylcholine. J Physiol 395:131-159.
    • (1988) J Physiol , vol.395 , pp. 131-159
    • Colquhoun, D.1    Ogden, D.C.2
  • 24
    • 0028224950 scopus 로고
    • Local anaesthetic blockade of neuronal nicotinic ACh receptor-channels in rat presympathetic ganglion cells
    • Cuevas J, Adams DJ (1994): Local anaesthetic blockade of neuronal nicotinic ACh receptor-channels in rat presympathetic ganglion cells. Br J Pharmacol 111:663-672.
    • (1994) Br J Pharmacol , vol.111 , pp. 663-672
    • Cuevas, J.1    Adams, D.J.2
  • 25
    • 0025291849 scopus 로고
    • 3H]quinacrine azide in the active state of the nicotinic acetylcholine receptor
    • 3H]quinacrine azide in the active state of the nicotinic acetylcholine receptor. J Biol Chem 265:11017-11029.
    • (1990) J Biol Chem , vol.265 , pp. 11017-11029
    • DiPaola, M.1    Kao, P.N.2    Karlin, A.3
  • 26
    • 0020083547 scopus 로고
    • Binding of depolarizing drugs to the ionic channel sites of the nicotinic acetylcholine receptor
    • Eldefrawi AT, Miller RE, Eldefrawi ME (1982): Binding of depolarizing drugs to the ionic channel sites of the nicotinic acetylcholine receptor. Biochem Pharmacol 31:1819-1822.
    • (1982) Biochem Pharmacol , vol.31 , pp. 1819-1822
    • Eldefrawi, A.T.1    Miller, R.E.2    Eldefrawi, M.E.3
  • 27
    • 0023948853 scopus 로고
    • High acetylcholine concentrations cause rapid inactivation before fast desensitization in nicotinic acetylcholine receptors from Torpedo
    • Forman SA, Miller KW (1988): High acetylcholine concentrations cause rapid inactivation before fast desensitization in nicotinic acetylcholine receptors from Torpedo. Biophys J 54:149-158.
    • (1988) Biophys J , vol.54 , pp. 149-158
    • Forman, S.A.1    Miller, K.W.2
  • 28
    • 0024597869 scopus 로고
    • Procaine rapidly inactivates acetylcholine receptors from Torpedo and competes with agonist for inhibition sites
    • Forman SA, Miller KW (1989): Procaine rapidly inactivates acetylcholine receptors from Torpedo and competes with agonist for inhibition sites. Biochemistry 28:1678-1685.
    • (1989) Biochemistry , vol.28 , pp. 1678-1685
    • Forman, S.A.1    Miller, K.W.2
  • 29
    • 0023198434 scopus 로고
    • Is agonist self-inhibition at the nicotinic acetylcholine receptor a nonspecific action?
    • Forman SA, Firestone LL, Miller KW (1987): Is agonist self-inhibition at the nicotinic acetylcholine receptor a nonspecific action? Biochemistry 26:2807-2814.
    • (1987) Biochemistry , vol.26 , pp. 2807-2814
    • Forman, S.A.1    Firestone, L.L.2    Miller, K.W.3
  • 30
    • 0020647560 scopus 로고
    • Sites of action of procaine at the motor end-plate
    • Gage PW, Hamill OP, Wachtel RE (1983): Sites of action of procaine at the motor end-plate, J Physiol 335:123-137.
    • (1983) J Physiol , vol.335 , pp. 123-137
    • Gage, P.W.1    Hamill, O.P.2    Wachtel, R.E.3
  • 34
    • 0017742507 scopus 로고
    • Fast kinetic studies on the interaction of cholinergic agonists with the membrane-bound acetylcholine receptor from Torpedo marmorata as revealed by quinacrine fluorescence
    • Grünhagen H-H, Iwatsubo M, Changeux J-P (1977): Fast kinetic studies on the interaction of cholinergic agonists with the membrane-bound acetylcholine receptor from Torpedo marmorata as revealed by quinacrine fluorescence. Eur J Biochem 80:225-242.
    • (1977) Eur J Biochem , vol.80 , pp. 225-242
    • Grünhagen, H.-H.1    Iwatsubo, M.2    Changeux, J.-P.3
  • 35
    • 0020621092 scopus 로고
    • Multiple sites of action of noncompetitive blockers on acetylcholine receptor rich membrane fragments from Torpedo marmorata
    • Heidmann T, Oswald RE, Changeux J-P (1983): Multiple sites of action of noncompetitive blockers on acetylcholine receptor rich membrane fragments from Torpedo marmorata. Biochemistry 22:3112-3127.
    • (1983) Biochemistry , vol.22 , pp. 3112-3127
    • Heidmann, T.1    Oswald, R.E.2    Changeux, J.-P.3
  • 36
    • 0024328738 scopus 로고
    • Distance between the agonist and noncompetitive inhibitor sites on the nicotinic acetylcholine receptor
    • Herz JM, Johnson DA, Taylor P (1989): Distance between the agonist and noncompetitive inhibitor sites on the nicotinic acetylcholine receptor. J Biol Chem 264:12439-12448.
    • (1989) J Biol Chem , vol.264 , pp. 12439-12448
    • Herz, J.M.1    Johnson, D.A.2    Taylor, P.3
  • 37
    • 0019176153 scopus 로고
    • Asymmetry of the acetylcholine channel revealed by quaternary anesthetics
    • Horn R, Brodwick MS, Dickey WD (1980): Asymmetry of the acetylcholine channel revealed by quaternary anesthetics. Science 210:205-207.
    • (1980) Science , vol.210 , pp. 205-207
    • Horn, R.1    Brodwick, M.S.2    Dickey, W.D.3
  • 38
    • 0028105948 scopus 로고
    • The histrionicotoxin-sensitive ethidium binding site is located outside of the transmembrane domain of the nicotinic acetylcholine receptor: A fluorescence study
    • Johnson DA, Nuss JM (1994): The histrionicotoxin-sensitive ethidium binding site is located outside of the transmembrane domain of the nicotinic acetylcholine receptor: A fluorescence study. Biochemistry 33:9070-9077.
    • (1994) Biochemistry , vol.33 , pp. 9070-9077
    • Johnson, D.A.1    Nuss, J.M.2
  • 39
    • 0024918350 scopus 로고
    • Explorations of the nicotinic acetylcholine receptor
    • Karlin A (1991): Explorations of the nicotinic acetylcholine receptor. Harvey Lect Ser 85:71-107.
    • (1991) Harvey Lect Ser , vol.85 , pp. 71-107
    • Karlin, A.1
  • 40
    • 0020075286 scopus 로고
    • Triphenylmethylphosphonium is an ion channel ligand of the nicotinic acetylcholine receptor
    • Lauffer L, Hucho F (1982): Triphenylmethylphosphonium is an ion channel ligand of the nicotinic acetylcholine receptor. Proc Natl Acad Sci USA 79:2406-2409.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 2406-2409
    • Lauffer, L.1    Hucho, F.2
  • 41
    • 0024213680 scopus 로고
    • Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor
    • Leonard RJ, Labarca CG, Charnet P, Davidson N, Lester HA (1988): Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor. Science 242:1578-1581.
    • (1988) Science , vol.242 , pp. 1578-1581
    • Leonard, R.J.1    Labarca, C.G.2    Charnet, P.3    Davidson, N.4    Lester, H.A.5
  • 42
    • 0026028911 scopus 로고
    • Activation of ion channels in the frog endplate by several analogues of acetylcholine
    • Marshall CG, Ogden D, Colquhoun D (1991): Activation of ion channels in the frog endplate by several analogues of acetylcholine. J Physiol 433:73-93.
    • (1991) J Physiol , vol.433 , pp. 73-93
    • Marshall, C.G.1    Ogden, D.2    Colquhoun, D.3
  • 43
    • 0017882845 scopus 로고
    • Voltage- And time-dependent action of histrionicotoxin on the endplate current of the frog muscle
    • Masukawa LM, Alburquerque EX (1978): Voltage- and time-dependent action of histrionicotoxin on the endplate current of the frog muscle. J Gen Physiol 72:351-367.
    • (1978) J Gen Physiol , vol.72 , pp. 351-367
    • Masukawa, L.M.1    Alburquerque, E.X.2
  • 44
    • 0026681427 scopus 로고
    • On the mechanism of mammalian neuronal type nicotinic acetylcholine receptor investigated by a rapid chemical kinetic technique. Detection and characterization of a short-lived, previously unobserved, main receptor form in PC12 cells
    • Matsubara N, Hess GP (1992): On the mechanism of mammalian neuronal type nicotinic acetylcholine receptor investigated by a rapid chemical kinetic technique. Detection and characterization of a short-lived, previously unobserved, main receptor form in PC12 cells. Biochemistry 31:5477-5487.
    • (1992) Biochemistry , vol.31 , pp. 5477-5487
    • Matsubara, N.1    Hess, G.P.2
  • 45
    • 0021331784 scopus 로고
    • Photoaffinity labeling of acetyl-choline receptor in millisecond time scale
    • Muhn P, Fahr A, Hucho F (1984): Photoaffinity labeling of acetyl-choline receptor in millisecond time scale. FEBS Lett 166:146-150.
    • (1984) FEBS Lett , vol.166 , pp. 146-150
    • Muhn, P.1    Fahr, A.2    Hucho, F.3
  • 46
    • 0020646202 scopus 로고
    • The charge carried by single-channel currents of rat cultured muscle cells in the presence of local anaesthetics
    • Neher E (1983): The charge carried by single-channel currents of rat cultured muscle cells in the presence of local anaesthetics. J Physiol 339:663-678.
    • (1983) J Physiol , vol.339 , pp. 663-678
    • Neher, E.1
  • 47
    • 0017905087 scopus 로고
    • Local anaesthetic transiently block current through single acetylcholine receptor channel
    • Neher E, Steinbach JH (1978): Local anaesthetic transiently block current through single acetylcholine receptor channel. J Physiol 277:153-176.
    • (1978) J Physiol , vol.277 , pp. 153-176
    • Neher, E.1    Steinbach, J.H.2
  • 48
    • 0027212222 scopus 로고
    • 3H-1cells: Characterized by laser-pulse photolysis in the microsecond-to-millisecond time region
    • 3H-1cells: Characterized by laser-pulse photolysis in the microsecond-to-millisecond time region. Biochemistry 32:3831-3835.
    • (1993) Biochemistry , vol.32 , pp. 3831-3835
    • Niu, L.1    Hess, G.P.2
  • 49
    • 0022758905 scopus 로고
    • The reaction site of a non-competitive antagonist in the δ subunit of the nicotinic acetylcholine receptor
    • Oberthur W, Muhn P, Baumann H, Lottspeich F, Wittmann-Liebold B, Hucho F (1986). The reaction site of a non-competitive antagonist in the δ subunit of the nicotinic acetylcholine receptor. EMBO J 5:1815-1819.
    • (1986) EMBO J , vol.5 , pp. 1815-1819
    • Oberthur, W.1    Muhn, P.2    Baumann, H.3    Lottspeich, F.4    Wittmann-Liebold, B.5    Hucho, F.6
  • 50
    • 0019795816 scopus 로고
    • Ultraviolet light-induced labelling by noncompetitive blockers of the acetylcholine receptor from Torpedo marmorata
    • Oswald RE, Changeux J-P (1981): Ultraviolet light-induced labelling by noncompetitive blockers of the acetylcholine receptor from Torpedo marmorata. Proc Natl Acad Sci USA 78:3925-3929.
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 3925-3929
    • Oswald, R.E.1    Changeux, J.-P.2
  • 51
    • 0021072763 scopus 로고
    • Acetylcholine receptor: Evidence for a regulatory binding site in investigations of suberyldicholine-induced transmembrane ion flux in Electrophorus electricus membrane vesicles
    • Pasquale EB, Takeyasu K, Udgaonkar JB, Cash DJ, Severski MC, Hess GP (1983): Acetylcholine receptor: Evidence for a regulatory binding site in investigations of suberyldicholine-induced transmembrane ion flux in Electrophorus electricus membrane vesicles. Biochemistry 22:5967-5973.
    • (1983) Biochemistry , vol.22 , pp. 5967-5973
    • Pasquale, E.B.1    Takeyasu, K.2    Udgaonkar, J.B.3    Cash, D.J.4    Severski, M.C.5    Hess, G.P.6
  • 52
    • 0028819573 scopus 로고
    • Site-selective photoaffinity-labeling of the Torpedo californica nicotinic acetylcholine receptor by azide derivatives of ethidium bromide
    • Pedersen SE (1995): Site-selective photoaffinity-labeling of the Torpedo californica nicotinic acetylcholine receptor by azide derivatives of ethidium bromide. Mol Pharmacol 47:1-9.
    • (1995) Mol Pharmacol , vol.47 , pp. 1-9
    • Pedersen, S.E.1
  • 54
    • 0021711376 scopus 로고
    • Potential-dependent phase partitioning of fluorescent hydrophobic ions in phospholipid vesicles
    • Raines DE, Cafiso DS (1984): Potential-dependent phase partitioning of fluorescent hydrophobic ions in phospholipid vesicles. J Membr Biol 82:241-247.
    • (1984) J Membr Biol , vol.82 , pp. 241-247
    • Raines, D.E.1    Cafiso, D.S.2
  • 55
    • 0025195179 scopus 로고
    • 3H]chlorpromazine labels three amino acids of the acetylcholine receptor γ subunit: Implications for the α-helical organization of regions MII and for the structure of the ion channel
    • 3H]chlorpromazine labels three amino acids of the acetylcholine receptor γ subunit: Implications for the α-helical organization of regions MII and for the structure of the ion channel. Proc Natl Acad Sci USA 87:4675-4679.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4675-4679
    • Revah, F.1    Galzi, J.-L.2    Giraudat, J.3    Haumont, P.4    Lederer, F.5    Changeux, J.-P.6
  • 57
    • 0021861363 scopus 로고
    • Kinetics of binding of membrane-active drugs to receptor sites
    • Rhodes DG, Sarmiento JG, Herbette LG (1985): Kinetics of binding of membrane-active drugs to receptor sites. Mol Pharmacol 27:612-623.
    • (1985) Mol Pharmacol , vol.27 , pp. 612-623
    • Rhodes, D.G.1    Sarmiento, J.G.2    Herbette, L.G.3
  • 58
    • 0019954790 scopus 로고
    • The kinetics of local anesthetic blockage of end-plate channels
    • Ruff RL (1982): The kinetics of local anesthetic blockage of end-plate channels. Biophys J 37:625-631.
    • (1982) Biophys J , vol.37 , pp. 625-631
    • Ruff, R.L.1
  • 59
    • 0021712302 scopus 로고
    • Regulatory properties of acetylcholine receptor: Evidence for two different inhibitory sites, one for acetylcholine and the other for a noncompetitive inhibitor of receptor function (procaine)
    • Shiono S, Takeyasu K, Udgaonkar JB, Delcour AH, Fujita N, Hess GP (1984): Regulatory properties of acetylcholine receptor: Evidence for two different inhibitory sites, one for acetylcholine and the other for a noncompetitive inhibitor of receptor function (procaine). Biochemistry 23:6889-6893.
    • (1984) Biochemistry , vol.23 , pp. 6889-6893
    • Shiono, S.1    Takeyasu, K.2    Udgaonkar, J.B.3    Delcour, A.H.4    Fujita, N.5    Hess, G.P.6
  • 60
    • 0021150988 scopus 로고
    • Agonists block currents through acetylcholine receptor channels
    • Sine SM, Steinbach JH (1984): Agonists block currents through acetylcholine receptor channels. Biophys J 46:277-284.
    • (1984) Biophys J , vol.46 , pp. 277-284
    • Sine, S.M.1    Steinbach, J.H.2
  • 61
    • 0019984781 scopus 로고
    • Effects of ethidium bromide on the nicotinic acetylcholine receptor
    • Sterz R, Hermes M, Peper K, Bradley RJ (1982): Effects of ethidium bromide on the nicotinic acetylcholine receptor. Eur J Pharmacol 80:393-399.
    • (1982) Eur J Pharmacol , vol.80 , pp. 393-399
    • Sterz, R.1    Hermes, M.2    Peper, K.3    Bradley, R.J.4
  • 62
    • 0021039676 scopus 로고
    • Acetylcholine receptor: Evidence for a voltage-dependent regulatory site for acetylcholine. Chemical kinetic measurements in membrane vesicles using a voltage clamp
    • Takeyasu K, Udgaonkar JB, Hess GP (1983): Acetylcholine receptor: Evidence for a voltage-dependent regulatory site for acetylcholine. Chemical kinetic measurements in membrane vesicles using a voltage clamp. Biochemistry 22:5973-5978.
    • (1983) Biochemistry , vol.22 , pp. 5973-5978
    • Takeyasu, K.1    Udgaonkar, J.B.2    Hess, G.P.3
  • 63
    • 0022539940 scopus 로고
    • Acetylcholine receptor: Characterization of the voltage-dependent regulatory (inhibitory) site for acetylcholine in membrane vesicles from Torpedo californica electroplax
    • Takeyasu K, Shiono S, Udgaonkar JE, Fujita N, Hess GP (1986): Acetylcholine receptor: Characterization of the voltage-dependent regulatory (inhibitory) site for acetylcholine in membrane vesicles from Torpedo californica electroplax. Biochemistry 25:1770-1776.
    • (1986) Biochemistry , vol.25 , pp. 1770-1776
    • Takeyasu, K.1    Shiono, S.2    Udgaonkar, J.E.3    Fujita, N.4    Hess, G.P.5
  • 64
    • 0027076457 scopus 로고
    • Can nicotine self-inhibition account for its low efficacy at the nicotinic acetylcholine receptor from Torpedo?
    • Tonner PH, Wood SC, Miller KW (1992): Can nicotine self-inhibition account for its low efficacy at the nicotinic acetylcholine receptor from Torpedo? Mol Pharmacol 42:890-897.
    • (1992) Mol Pharmacol , vol.42 , pp. 890-897
    • Tonner, P.H.1    Wood, S.C.2    Miller, K.W.3
  • 65
    • 0027506299 scopus 로고
    • Nicotinic acetylcholine receptor at 9 Å resolution
    • Unwin N (1993): Nicotinic acetylcholine receptor at 9 Å resolution. J Mol Biol 229:1101-1124.
    • (1993) J Mol Biol , vol.229 , pp. 1101-1124
    • Unwin, N.1
  • 66
    • 0028921479 scopus 로고
    • Acetylcholine receptor channel imaged in the open state
    • Unwin N (1995): Acetylcholine receptor channel imaged in the open state. Nature 373:37-43.
    • (1995) Nature , vol.373 , pp. 37-43
    • Unwin, N.1
  • 67
    • 0026733435 scopus 로고
    • Quinacrine binds to the lipid-protein interface of the Torpedo acetylcholine receptor: A fluorescence study
    • Valenzuela CF, Kerr JA, Johnson DA (1992): Quinacrine binds to the lipid-protein interface of the Torpedo acetylcholine receptor: A fluorescence study. J Biol Chem 267:8238-8244.
    • (1992) J Biol Chem , vol.267 , pp. 8238-8244
    • Valenzuela, C.F.1    Kerr, J.A.2    Johnson, D.A.3
  • 68
    • 0028268955 scopus 로고
    • Transverse distance between the membrane and the agonist binding sites on the Torpedo acetylcholine receptor: A fluorescence study
    • Valenzuela CF, Weign P, Yguerabide J, Johnson DA (1994): Transverse distance between the membrane and the agonist binding sites on the Torpedo acetylcholine receptor: A fluorescence study. Biophys J 66:674-682.
    • (1994) Biophys J , vol.66 , pp. 674-682
    • Valenzuela, C.F.1    Weign, P.2    Yguerabide, J.3    Johnson, D.A.4
  • 69
    • 0026625673 scopus 로고
    • Agonist-induced changes in the structure of the acetylcholine receptor M2 regions revealed by photoincorporation of an uncharged nicotinic noncompetitive antagonist
    • White BH, Cohen JB (1992): Agonist-induced changes in the structure of the acetylcholine receptor M2 regions revealed by photoincorporation of an uncharged nicotinic noncompetitive antagonist. J Biol Chem 267:15770-15783.
    • (1992) J Biol Chem , vol.267 , pp. 15770-15783
    • White, B.H.1    Cohen, J.B.2
  • 70
    • 0025786180 scopus 로고
    • 125I]iodophenyl)diazirine is a novel noncompetitive antagonist of the nicotinic acetylcholine receptor
    • 125I]iodophenyl)diazirine is a novel noncompetitive antagonist of the nicotinic acetylcholine receptor. J Biol Chem 266:21595-21607.
    • (1991) J Biol Chem , vol.266 , pp. 21595-21607
    • White, B.H.1    Howard, S.2    Cohen, S.G.3    Cohen, J.B.4
  • 71
    • 0028120969 scopus 로고
    • Ethanol stabilizes the open channel state of the Torpedo nicotinic acetylcholine receptor
    • Wu G, Tonner PH, Miller KW (1993): Ethanol stabilizes the open channel state of the Torpedo nicotinic acetylcholine receptor. Mol Pharmacol 45:102-108.
    • (1993) Mol Pharmacol , vol.45 , pp. 102-108
    • Wu, G.1    Tonner, P.H.2    Miller, K.W.3
  • 72
    • 0028344133 scopus 로고
    • Theory for establishing proximity relations in biological membranes by excitation energy transfer measurements
    • Yguerabide J (1994): Theory for establishing proximity relations in biological membranes by excitation energy transfer measurements. Biophys J 66:683-693.
    • (1994) Biophys J , vol.66 , pp. 683-693
    • Yguerabide, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.