Dietary cholesterol inhibits the development of aberrant crypt foci in the colon

Nutrition and Cancer

Volumn 25, Issue 2, 1996, Pages 111-117

  El Sohemy, Ahmed ^a   Kendall, Cyril W C ^a   Rao, A Venket ^a   Archer, Michael C ^a   Bruce, W Robert ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AZOXYMETHANE; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL INTAKE; CHOLESTEROL SYNTHESIS; COLON CANCER; CONTROLLED STUDY; FEMALE; GAS CHROMATOGRAPHY; INTESTINE CRYPT; LIPID OXIDATION; MOUSE; NONHUMAN; PRECANCER;

EID: 0029862981     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1080/01635589609514433     Document Type: Article

References (25)

1. Liu, K, Stamler, J, Moss, D, Garside, D, Persky, V, et al.: "Dietary Cholesterol, Fat and Fibre, and Colon Cancer Mortality. An Analysis of International Data." Lancet i, 752-755, 1979.
2. Rao, AV, Janezic, SA, Friday, D, and Kendall, CW: "Dietary Cholesterol Enhances the Induction and Development of Colonic Preneoplastic Lesions in C57BL/6J and BALB/cJ Mice Treated With Azoxymethane." Cancer Lett 63, 249-257, 1992.
3. Kendall, CW, Janezic, SA, Friday, D, and Rao, AV: "Dietary Cholesterol Enhances Preneoplastic Aberrant Crypt Formation and Alters Cell Proliferation in the Murine Colon Treated With Azoxymethane." Nutr Cancer 17, 107-114, 1992.
4. Kendall, CW, Koo, M, Sokoloff, E, and Rao, AV: "Effect of Dietary Oxidized Cholesterol on Azoxymethane-Induced Colonic Preneoplasia in Mice." Cancer Lett 66, 241-248, 1992.
5. Cruse, JP, Lewin, MR, Ferulano, GP, and Clark, CG: "Co-Carcinogenic Effects of Dietary Cholesterol in Experimental Colon Cancer." Nature 276, 822-825, 1978.
6. Hiramatsu, Y, Takada, H, Yamamura, M, Hioki, K, Saito, K, et al.: "Effect of Dietary Cholesterol on Azoxymethane-Induced Colon Carcinogenesis in Rats." Carcinogenesis 4, 553-558, 1983.
7. Broitman, SA, Vitale, JJ, Vavrousek-Jakuba, E, and Gottlieb, L: "Polyunsaturated Fat, Cholesterol and Large Bowel Tumorigenesis." Cancer 40, 2455-2463, 1977.
8. Klurfeld, DM, Aglow, E, Tepper, SA, and Kritchevsky, D: "Modification of Dimethylhydrazine-Induced Carcinogenesis in Rats by Dietary Cholesterol." Nutr Cancer 5, 16-25, 1983.
9. Cruse, JP, Lewin, MR, and Clark, CG: "An Investigation Into the Mechanism of Co-Carcinogenesis of Dietary Cholesterol During the Induction of Colon Cancer in Rats by 1,2-Dimethylhydrazine." Clin Oncol 10, 213-220, 1984.
10. Reddy, BS, and Watanabe, K: "Effect of Cholesterol Metabolites and Promoting Effect of Lithocholic Acid in Colon Carcinogenesis in Germ-Free and Conventional F344 Rats." Cancer Res 39, 1521-1524, 1979.
11. Cohen, BI, Raicht, RF, and Fazzini, E: "Reduction of N-Methyl-N-Nitrosourea-Induced Colon Tumors in the Rat by Cholesterol." Cancer Res 42, 5050-5052, 1982.
12. Wargovich, MJ, and Felkner, IC: "Metabolic Activation of DMH by Colonic Microsomes: A Process Influenced by Type of Dietary Fat." Nutr Cancer 4, 146-153, 1982.
13. Bird, RP, McLellan, EA, and Bruce, WR: "Aberrant Crypts, Putative Precancerous Lesions, in the Study of the Role of Diet in the Aetiology of Colon Cancer." Cancer Surv 8, 189-200, 1989.
14. Archei, MC, Bruce, WR, Chan, CC, Corpet, DE, Medline, A, et al.: "Aberrant Crypt Foci and Microadenoma as Markers for Colon Cancer." Environ Health Perspect 98, 195-197, 1992.
15. Bruce, WR, Archer, MC, Corpet, DE, Medline, A, Minkin, S, et al.: "Diet, Aberrant Crypt Foci and Colorectal Cancer." Mutat Res 290, 111-118, 1993.
16. Bird, RP: "Observation and Quantification of Aberrant Crypts in the Murine Colon Treated with a Colon Carcinogen: Preliminary Findings." Cancer Lett 37, 147-151, 1987.
17. Sevanian, A, and Peterson, AR: "The Cytotoxic and Mutagenic Properties of Cholesterol Oxidation Products." Food Chem Toxicol 24, 1103-1110, 1986.
18. Morin, RJ, Hu, B, Peng, S-K, and Sevanian, A: "Cholesterol Oxides and Carcinogenesis." J Clin Lab Anal 5, 219-225, 1991.
19. Huneeus, VR, Wiley, MH, and Siperstein, MD: "Essential Role for Mevalonate Synthesis in DNA Replication." Proc Natl Acad Sci USA 76, 5056-5060, 1979.
20. Siperstein, MD: "Role of Cholesterogenesis and Isoprenoid Synthesis in DNA Replication and Cell Growth." J Lipid Res 25, 1462-1468, 1984.
21. Goldstein, JL, and Brown, MS: "Regulation of the Mevalonate Pathway." Nature 343, 425-430, 1990.
22. Bird, RP: "Role of Aberrant Crypt Foci in Understanding the Pathogenesis of Colon Cancer." Cancer Lett 93, 55-71, 1995.
23. Goldstein, JL, and Brown, MS: "Progress in Understanding the LDL Receptor and HMG-CoA Reductase, Two Membrane Proteins That Regulate the Plasma Cholesterol." J Lipid Res 25, 1450-1461, 1984.
24. Osada, K, Sasaki, E, and Sugano, M: "Inhibition of Cholesterol Absorption by Oxidized Cholesterol in Rats." Biosci Biotech Biochem 58, 782-783, 1994.
25. El-Sohemy, A, Bruce, WR, and Archer, MC: "Inhibition of Rat Mammary Tumorigenesis by Dietary Cholesterol." Carcinogenesis 17, 159-162, 1996.