Transcription factor PU.1 mediates induction of c-fms in vascular smooth muscle cells: A mechanism for phenotypic change to phagocytic cells

Molecular and Cellular Biology

Volumn 16, Issue 5, 1996, Pages 2264-2273

  Inaba, Toshimori ^a   Gotoda, Takanari ^a   Ishibashi, Shun ^a   Harada, Kenji ^a   Ohsuga, Jun Ichi ^a   Ohashi, Ken ^a   Yazaki, Yoshio ^a   Yamada, Nobuhiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; COLONY STIMULATING FACTOR 1; COLONY STIMULATING FACTOR RECEPTOR; COMPLEMENTARY DNA; DNA FRAGMENT; EPIDERMAL GROWTH FACTOR; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR BB; TRANSCRIPTION FACTOR;

ANIMAL CELL; AORTA; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; BINDING SITE; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION; GENE INDUCTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MACROPHAGE FUNCTION; NONHUMAN; NORTHERN BLOTTING; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; RABBIT; TUNICA MEDIA; VASCULAR SMOOTH MUSCLE;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0029862865     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.5.2264     Document Type: Article

References (39)

1. Aronheim, A., H. Ohlsson, C. W. Park, T. Edlund, and M. Walker. 1991 Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta-cells and lymphocytes. Nucleic Acids Res 19: 3893-3899.
2. Bain, G., E. C. R. Maandag, D. J. Izon, D. Amsen, A. M. Kruisbeek, B. C. Weintraub, I. Krop, M. S. Schlissel, A. J. Feeney, M. V. Roon, M. V. D. Valk, H. P. T. Riele, A. Berns, and C. Murre. 1994. E2A proteins are required for proper E cell development and initiation of immunoglobulin gene rearrangements. Cell 79:885-892.
3. Benezra, R., R. L. Davis, D. Lockshon, D. L. Turner, and H. Weintraub. 1990. The protein Id, a negative regulator of helix-loop-helix DNA binding proteins. Cell 61:49-59.
4. Blackwell, T. K., and H. Weintraub. 1990 Differences and similarities in DNA-binding preferences of Myo-D and E2A protein complexes revealed by binding site selection. Science 250:1104-1110
5. Brown, M. S., and J. L. Goldstein. 1986. A receptor pathway for cholesterol homeostasis. Science 232:34-37.
6. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolated by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
7. Clark, S. C., and R. Kamen. 1987. The human hematopoietic colony-stimulating factors. Science 236:1229-1237.
8. Fisher-Dzoga, K., R. M. Jones, D. Vesselinovitch, and R. W. Wissler. 1973 Ultrastructural and immunohistochemical studies of primary cultures of aortic medial cells Exp. Mol. Pathol. 18:162-176.
9. Fried, M., and D. M. Crothers. 1987 Equilibria and kinetics of lac repressor-operator interactions by PAGE Nucleic Acids Res. 9:6505-6525.
10. Goldstein, J. L., Y. K. Ho, S. K. Basu, and M. S. Brown. 1979 Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition Proc. Natl. Acad. Sci. USA 76:333-337
11. Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044-1051.
12. Gotoda, T., N. Yamada, M. Kawamura, K. Kozaki, N. Mori, S. Ishibashi, H. Shimano, F. Takaku, Y. Yazaki, Y. Furuichi, and T. Murase. 1991 Heterogeneous mutations in the human lipoprotein lipase gene in patients with familial lipoprotein lipase deficiency. J Clin. Invest. 88:1856-1864
13. Harvel, R. J., H. A. Eder, and J. J. Bragdom. 1955. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J. Clin. Invest. 34:1345-1353.
14. Herbomel, P., B. Bourachot, and M. Yaniv. 1984. Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma. Cell 39:653-662.
15. Inaba, T., T. Gotoda, K. Harada, M. Shimada, J. Ohsuga, S. Ishibashi, Y. Yazaki, and N. Yamada. 1995. Induction of sustained expression of protooncogene c-fms by platelet-derived growth factor, epidermal growth factor, and basic fibroblast growth factor, and its suppression by interferon-γ and macrophage colony-stimulating factor in human aortic medial smooth muscle cells. J. Clin. Invest. 95:1133-1139.
16. Inaba, T., T. Gotoda, H. Shimano, M. Shimada, K. Harada, K. Kozaki, Y. Watanabe, E. Hoh, K. Motoyoshi, Y. Yazaki, and N. Yamada. 1992 Platelet-derived growth factor induces c-fms and scavenger receptor genes in vascular smooth muscle cells. J. Biol. Chem. 267:13107-13112.
17. Inaba, T., T. Gotoda, H. Shimano, M. Shimada, T. Kadowaki, K. Momomura, K. Motoyoshi, T. Tsukada, N. Morisaki, Y. Saito, S. Yoshida, Y. Yazaki, F. Takaku, and N. Yamada. 1992. Expression of M-CSF receptor encoded by c-fms on smooth muscle cells derived from arteriosclerotic lesion. J Biol. Chem. 267:5693-5699.
18. Ishibashi, S., T. Inaba, H. Shimano, K. Harada, I. Inoue, H. Mokuno, N. Mori, T. Gotoda, F. Takaku, and N. Yamada. 1990 Monocyte colony-stimulating factor enhances uptake and degradation of acetylated low density lipoproteins and cholesterol esterification in human monocyte-derived macrophages J. Biol. Chem 265:14109-14117.
19. Klemsz, M. J., S. R. McKercher, A. Celada, C. V. Beveren, and R. A. Maki. 1990. The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene. Cell 61:113-124.
20. Lassar, A. B., R. L. Davis, W. E. Wright, T. Kadesch, C. Murre, A. Voronova, D. Baltimore, and H. Weintraub. 1991. Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/47-lilce proteins in vivo. Cell 66:305-315.
21. Moulton, K. S., K. Semple, H. Wu, and C. K. Glass. 1994. Cell specific expression of the macrophage scavenger receptor gene is dependent on PU.1 and a composite AP-1/ets motif. Mol. Cell. Biol. 14:4408-4418.
22. Murre, C., P. S. McCaw, and D. Baltimore. 1989 A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell 56:777-783.
23. Pahl, H. L., R. J. Scheibe, D. E. Zhang, H. M. Chen, D. L. Galson, R. Maki, and D. G. Tenen. 1993. The proto-oncogene PU.1 regulates expression of the myeloid-specific CD 11b promoter. J Biol. Chem. 268:5014-5020.
24. Reddy, M. A., B. S. Yang, X. Yue, C. J. K. Barnett, I. L. Ross, M. J. Sweet, D. Hume, and M. C. Osttowski. 1994. Opposing actions of c-ets/PU 1 and c-myb protooncogene products in regulating the human and mouse colony-stimulating factor-1 receptor (c-fms) genes. J. Exp. Med. 180:2309-2319.
25. Roberts, W. M., L. H. Shapiro, R. A. Ashmun, and A. T. Look. 1992. Transcription of the human colony-stimulating factor-1 receptor gene is regulated by separate tissue-specific promoters. Blood 79:586-593
26. Rosmarin, A. G., D. Caprio, R. Levy, and C. Simkevich. 1995. CD 18 promoter requires PU.1 transcription factor for myeloid activity. Proc Natl. Acad. Sci. USA 92:801-805.
27. Ross, R. 1993. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature (London) 362:801-809.
28. Ross, R., E. W. Raines, and D. F. Bowen-Pope. 1986. The biology of platelet-derived growth factor. Cell 46:155-169.
29. Roussel, M. F., T. J. Dull, C. W. Rettenmier, P. Ralph, A. Ullrich, and C. Sherr. 1987. Transforming potential of the c-fms proto-oncogene Nature (London) 325:549-552
30. Saito, Y., H. Bujo, N. Morisaki, K. Shirai, and S. Yoshida. 1988. Proliferation and LDL binding of cultured intimal smooth muscle cells from rabbits. Atherosclerosis 69:161-164
31. Schreiber, E., P. Matthias, M. M. Muller, and W. Schaffner. 1989. Rapid detection of octamer binding proteins with mini-extracts, prepared from a small number of cells. Nucleic Acids Res. 17:6419.
32. Sherr, C. J., C. W. Rettenmier, R. Sacca, M. F. Roussel, A. T. Look, and E. R. Stanley. 1985. The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1. Cell 41:665-676.
33. Smith, J. R., T. F. Osborne, J. L. Goldstein, and M. S. Brown. 1990. Identification of nucleotides responsible for enhancer activity of sterol regulatory element in low density lipoprotein receptor gene. J. Biol. Chem. 265:2306-2310.
34. Stanley, E. R., and P. M. Heard. 1977. Factors regulating macrophage production and growth: purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells. J. Biol. Chem. 252:4305-4312.
35. Steinberg, D., S. Parthasarathy, T. E. Carew, J. C. Khoo, and J. L. Witztum. 1989. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 320:915-924.
36. Thyberg, J., U. Hedin, M. Sjolund, L. Palmberg, and B. A. Bottger. 1990. Regulation of differentiated properties and proliferation of arterial smooth muscle cells. Arteriosclerosis 10:966-990.
37. Zaret, D. E., J. K. Liu, and C. M. DiPersio. 1990. Site-directed mutagenesis reveals a liver transcription factor essential for the albumin transcriptional enhancer Proc. Natl. Acad. Sci USA 87:965-977.
38. Zhang, D.-E., C. J. Hetherington, H.-M. Chen, and D. G. Tenen. 1994. The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor. Mol. Cell. Biol. 14:373-381
39. Zhuang, Y., P. Soriano, and H. Weintraub. 1994. The helix-loop-helix gene E2A is required for B cell formation. Cell 79:875-884.