TrkC isoforms with inserts in the kinase domain show impaired signaling responses

Journal of Biological Chemistry

Volumn 271, Issue 10, 1996, Pages 5691-5697

  Tsoulfas, Pantelis ^a,b   Stephens, Robert M ^a   Kaplan, David R ^a,c   Parada, Luis F ^a,d  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN; NEUROTROPHIN 3; PHOSPHOLIPASE C; PROTEIN TYROSINE KINASE; TYROSINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME PHOSPHORYLATION; ENZYME POLYMORPHISM; GENETIC TRANSCRIPTION; NERVE CELL DIFFERENTIATION; NEURITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SYMPATHETIC NERVE;

ANIMALS; CELL DIFFERENTIATION; GENE EXPRESSION; GENES, FOS; GENES, IMMEDIATE-EARLY; GENES, JUN; HUMANS; ISOENZYMES; KINETICS; MUTAGENESIS, INSERTIONAL; NERVE GROWTH FACTORS; NEURITES; NEUROTROPHIN 3; PC12 CELLS; PHOSPHOTYROSINE; RATS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, TRKA; RECEPTOR, TRKC; RECEPTORS, NERVE GROWTH FACTOR; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

ANIMALIA;

EID: 0029862733     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.10.5691     Document Type: Article

References (56)

1. van der Geer, P., Hunter, T., and Lindberg, R. A (1994) Annu. Rev. Cell Biol. 10, 251-337
2. Snider, W. D. (1994) Cell 77, 627-638
3. Ernfors, P., Lee, K.-F., Kucera, J., and Jaenisch, R. (1994) Cell 77, 503-512
4. Farin̂as, I., Jones, K., Backus, C., Wang, X.-Y., and Reichardt, L. F. (1994) Nature 369, 658-661
5. Klein, R., Silos-Santiago, I , Smeyne, R. J., Lira, S. A., Brambilla, R., Bryant, S., Zhang, L., Snider, N. D., and Barbacid, M. (1994) Nature 368, 249-251
6. Tessarollo, L., Vogel, K. S., Palko, M.-E., Reid, S. W., and Parada, L. F. (1994) Proc. Natl. Acad. Sci U. S A. 91, 11844-11848
7. Greene, L. A., and Tischler, A. (1976) Proc. Natl. Acad. Sci. U. S. A. 73, 2424-2428
8. Kaplan, D. R., Hempstead, B. L., Martin-Zanca, D., Chao, M. V., and Parada, L. F. (1991) Science 252, 554-558
9. Kaplan, D. R., Martin-Zanca, D., and Parada, L. F. (1991) Nature 350, 158-160
10. Klein, R., Jing, S , Nandun, V., O'Rourke, E., and Barbacid, M. (1991) Cell 65, 189-197
11. Urfer, R., Tsoulfas, P., O'Connell, L., Shelton, D. L., Parada, L. F., and Presta, L. G. (1995) EMBO J. 14, 2795-2805
12. Perez, P., Coll, P, M., Hempstead, B. L., Martin-Zanca, D., and Chao, M. V. (1995) Mol. Cell. Neurosci. 6, 97-105
13. Stephens, R. M., Loeb, D. M., Copeland, T. D., Pawson, T., Greene, L. A., and Kaplan, D. R. (1994) Neuron 12, 691-705
14. Obermeier, A., Lammers, R., Wiesmüller, K.-H., Jung, G., Schlessinger, J., and Ullrich, A. (1993) J. Biol. Chem. 268, 22963-22966
15. Kaplan, D. R., and Stephens, R. M. (1994) J. Neurobiol. 25, 1404-1417
16. Loeb, D. M., Stephens, R. M., Copeland, T., Kaplan, D. R., and Greene, L. A. (1994) J. Biol. Chem. 269, 8901-8910
17. Obermeier, A., Bradshaw, R. A., Seedorf, K., Choidas, A , Schlessinger, J., and Ullrich, A. (1994) EMBO J. 13, 1585-1590
18. Thomas, S. M., DeMarco, M., D'Arcangelo, G., Halegoua, S , and Brugge, J. S. (1992) Cell 68, 1031-1040
19. Wood, K. W., Samecki, C., Roberts, T. M., and Blenis, J. (1992) Cell 68, 1041-1050
20. Rozakis-Adcock, M., McGlade, J., Mbamalu, G., Pelicci, G., Daly, R., Li, W., Batzer, A., Thomas, S., Brugge, J., Pelicci, P. G., Schlessinger, J., and Pawson, T. (1992) Nature 360, 689-692
21. Cowley, S., Paterson, H., Kemp, P., and Marshall, C. J. (1994) Cell 77, 841-852
22. Kimura, K., Hattori, S., Kabuyama, Y., Shizawa, Y , Takayanagi, J., Nakamura, S., Toki, S., Matsuda, Y., Onodera, K., and Fukui, Y. (1994) J. Biol. Chem. 269, 18961-18967
23. Yao, R. I., and Cooper, G. M. (1995) Science 267, 5206-5208
24. Peng, X., Greene, L. A., Kaplan, D. R., and Stephens, R. M. (1995) Neuron 15, 395-406
25. Ip, N. Y., Stitt, J. N., Tapley, P., Klein, R., Glass, D J., Fandl, J , Greene, L. A., Barbacid, M., and Yancopoulos, G D (1993) Neuron 10, 137-149
26. Tsoulfas, P., Soppet, D., Escandón, E., Tessarollo, L., Mendoza-Ramirez, J.-L., Rosenthal, A., Nikolics, K., and Parada, L. F. (1993) Neuron 10, 975-990
27. Valenzuella, D. M., Maisonpierre, P C., Glass. D J , Rojar, E., Nuñez, L., Kong, Y., Gies, D. R., Stitt, T., Ip, N. Y., and Yancopoulos, G. D. (1993) Neuron 10, 963-974
28. Lamballe, F., Tapley, P., and Barbacid, M. (1993) EMBO J. 12, 3083-3094
29. Offenhäuser, N., Böhn-Matthaei, R., Tsoulfas, P., Parada, L. F., and Meyer, M. (1995) Eur. J. Neurosci. 7, 917-925
30. Cordon-Cardo, C., Tapley, P., Jing, S , Nandun, V , O'Rourke, E., Lamballe, F., Kovary, K., Klein, R., Jones, K., Reichardt, L. F., and Barbacid, M. (1991) Cell 66, 173-183
31. Hempstead, B. L., Rabin, S. J., Kaplan, L., Reid, S. W., Parada, L. F., and Kaplan, D. R. (1992) Neuron 9, 883-896
32. Traverse, S., Seedorf, K., Paterson, H., Marshall, C , Cohen, P , and Ullrich, A. (1994) Curr. Biol 4, 694-701
33. Dikic, I., Schlessinger, J., and Lax, I. (1994) Curr. Biol. 4, 702-708
34. Halegoua, S., Armstrong, R. C., and Kremer, N. E. (1991) Curr. Top. Microbiol. Immunol. 165, 119-170
35. Greenberg, M. E., Greene, L A., and Ziff, E. B (1985) J. Biol. Chem. 260, 14101-14110
36. Wu, B., Fodor, E. J., Edwards, R H., and Rutter, W. J. (1989) J. Biol. Chem. 264, 9000-9003
37. Milbrandt, J (1987) Science 238, 797-799
38. Varnum, B C , Lim, R. W., Sukhatme, V. P., and Herschman, H, R, (1989) Oncogene 4, 119-120
39. Hazel, T. G , Nathans, D., and Lau, L. F. (1988) Proc. Natl. Acad. Sci. U. S A. 85, 8444-8448
40. Milbrandt, J. (1988) Neuron 1, 183-188
41. Varnum, B. C , Lim, R. W., and Herschman, H R. (1989) Oncogene 4, 1263-1265
42. Danielson, P. E., Forss-Petter, S., Brow, M. A., Calvatta, L., Milner, R. J., and Sutcliff, J G. (1988) DNA (NY) 1, 261-269
43. Kaplan D. R., and Knusel, B. (1996) in Handbook of Experimental Immunology. (Noble, M., ed) Blackwell Scientific Publications, Cambridge, MA, in press
44. Greene, L. A , and Tischler, A. S. (1982) Adv. Cell. Neurobiol 3, 373-414
45. Qiu, M.-S., and Greene, S. H. (1991) Neuron 7, 937-946
46. Marshall, C. J. (1995) Cell 80, 179-185
47. Soltoff, S. P., Rabin, S. L., Cantley, L C., and Kaplan, D. R. (1992) J. Biol. Chem. 267, 17472-17477
48. Raffioni, S., and Bradshaw, R. A. (1992) Proc. Natl. Acad. Sci U. S. A. 89, 9121-9125
49. Vambutas, V., Kaplan, D. R., Sells, M.-A., and Chernoff, J. (1995) J Biol. Chem 270, 25629-25633
50. Park, D., and Rhee, S. G. (1992) Mol. Cell. Biol. 12, 5816-5823
51. Hubbard, S. R., Wei, L., Ellis, L., and Hendrickson, W. A. (1994) Nature 372, 746-754
52. Knusel, B., Rabin, S. J , Hefti, F., and Kaplan, D. R. (1994) J. Neurosci. 14, 1542-1554
53. Rabin, S. J., Cleghon, V., and Kaplan, D. R. (1993) Mol. Cell. Biol. 13, 2203-2213
54. Chomczynski, P., and Sacchi, N. (1987) Anal. Biochem. 162, 156-15
55. Obermeier, A., Halfter, H , Wiesmuller, K.-H., Jung, G., Schlessinger, J., and Ullrich, A. (1993) EMBO J. 12, 933-941
56. Guiton, M., Gunn-Moore, F J , Glass, D. J., Geis, D. R., Yancopoulos, G. D., and Tavare, J. M. (1995) J. Biol. Chem. 270, 20384-20390