Snake venom proteins modulating the interaction between von Willebrand factor and platelet glycoprotein Ib

Thrombosis and Haemostasis

Volumn 76, Issue 5, 1996, Pages 633-639

  Fujimura, Yoshihiro ^a   Kawasaki, Tomihisa ^b   Titani, Koiti ^c  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b ASTELLAS PHARMA INC   (Japan)

^c FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DISULFIDE; GLYCOPROTEIN IB; SNAKE VENOM; VON WILLEBRAND FACTOR;

AMINO ACID SEQUENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW;

EID: 0029862473     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0038-1650636     Document Type: Review

References (62)

1. Girma J-P, Meyer D, Verweij CL, Pannekoek H, Sixma JJ. Structure-function relationship of human von Willebrand factor. Blood 1987; 70: 605-11.
2. Sadler JE. von Willebrand factor. J Biol Chem 1991; 266: 18172-8.
3. Fujimura Y, Titani K. Structure and function of von Willebrand factor. In: Haemostsis and Thrombosis, 3rd edn. Bloom AL, Forbes CD, Thomas DP, Tuddenham EGD (eds), Churchill Livingstone, London, pp 379-95 (1993).
4. Howard MA, Firkin BG. Ristocetin - a new tool in the investigation of platelet aggregation. Thromb Diath Haemorrh 1978; 26: 362-9.
5. Read MS, Shermer RW, Brinkhous KM. Venom coagglutinin: an activator of platelet aggregation dependent on von Willebrand factor. Proc Natl Acad Sci USA 1978; 75: 4514-8.
6. Brinkhous KM, Read MS, Fricke WA, Wagner RH. Botrocetin (venom coagglutinin): reaction with a broad spectrum of multimeric forms of factor VIII macromolecular complex. Proc Natl Acad Sci USA 1983; 80: 1463-6.
7. Moake JL, Turner NA, Stathopoulos NA, Nolasco L, Hellums JD. Shear-induced platelet aggregation can be mediated by vWF released from platelets, as well as by exogenous large or unusually large vWF multimers, requires adenosine diphosphate, and is resistant to aspirin. Blood 1988; 71: 1366-74.
8. Ikeda Y, Handa M, Kamata T, Kawano K, Kawai Y, Watanabe K, Kawakami K, Sakai K, Fukuyama M, Itagaki I, Yoshioka A, Ruggeri ZM. Transmembrane calcium influx associated with von Willebrand factor binding to GPIb in the initiation of shear-induced platelet aggregation. Thromb Haemost 1993; 69: 496-502.
9. Alevriadou BR, Moake JL, Turner NA, Ruggeri ZM, Folie BJ, Phillips MD, Schreiber AB, Hrinda ME, McIntire LV. Real-time analysis of shear-dependent thrombus formation and its blockade by inhibitors of von Willebrand factor binding to platelets. Blood 1993; 81: 1263-76.
10. Savage B, Sadlivar E, Ruggeri ZM. Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor. Cell 1996; 84: 289-97.
11. Kroll MH, Harris TS, Moake JL, Handin RI, Schafer AI. von Willebrand factor binding to GPIb initiates signals for for platelet activation. J Clin Invest 1991; 88: 1568-73.
12. Ozaki Y, Satoh K, Yatomi Y, Miura S, Fujimura Y, Kume S. Protein tyrosine phosphorylation in human platelets induced by interaction between glycoprotein Ib and von Willebrand factor. Biochem Biophys Acta 1995; 1243: 482-8.
13. Handa M, Titani K, Holland LZ, Roberts JR, Ruggeri ZM. The von Willebrand factor-binding domain of platelet membrane glycoprotein Ib. Proc Natl Acad Sci USA 1986; 261: 12579-85.
14. Titani K, Takio K, Handa M, Ruggeri ZM. Amino acid sequence of the von Willebrand factor-binding domain of platelet membrane glycoprotein Ib. Proc Natl Acad Sci USA 1987; 84: 5610-4.
15. 2-glycoprotein. Proc Natl Acad Sci USA 1987; 84: 5615-9.
16. Hess D, Schaller J, Rickli EE, Clemetson KJ. Identification to the disulphide bonds in human platelet glycocalicin. Eur J Biochem 1991; 199: 389-93.
17. Cruz MA, Petersen E, Turci SM, Handin RI. Functional analysis of a recombinant glycoprotein Ibα polypeptide which inhibits von Willebrand factor binding to the platelet glycoprotein Ib-IX complex and to collagen. J Biol Chem 1992; 267: 1303-9.
18. Nurden AT. Human platelet membrane glycoproteins. In: Haemostasis and Thrombosis, 3rd edn. Bloom AL, Forbes CD, Thomas DP, Tuddenham EGD (eds), Churchill Livingstone, London, pp 115-165 (1993).
19. Read MS, Potter JY, Brinkhous KM. Role of botrocetin in platelet agglutination: Formation of an activated complex of botrocetin and von Willebrand factor. Blood 1989; 74: 1031-5.
20. Andrews RK, Booth WJ, Gorman JJ, Castaldi PA, Berndt MC. Purification of botrocetin from Bothrops jararaca venom. Analysis of the botrocetin- mediated interaction between von Willebrand factor and the human platelet membrane glycoprotein Ib-IX complex. Biochemistry 1989; 28: 8317-26.
21. Okumura T, Lombart C, Jamieson GA. Platelet glycocalicin II. Purification and characterization. J Biol Chem 1976; 251: 5950-5.
22. Fujimura Y, Titani K, Usami Y, Suzuki M, Oyama R, Matsui T, Fukui H, Sugimoto M, Ruggeri ZM. Isolation and chemical characterization of two structurally and functionally distinct forms of botrocetin, the platelet coagglutinin isolated from the venom of Bothrops jararaca. Biochemistry 1991; 30: 1957-64.
23. Paine MJI, Desmond HP, Theakston DG, Crampton JM. Purification, cloning, and molecular characterization of a high molecular weight hemorrhagic metalloprotease, jararhagin, from Bothrops jararaca venom. J Biol Chem 1992; 267: 22869-76.
24. Usami Y, Fujimura Y, Miura S, Shima H, Yoshioka A, Hirano K, Suzuki M, Titani K. A 28 kDa-protein with disintegrin-like structure (jararhagin-C) purified from Bothrops jararaca venom inhibits collagen- and ADP-induced platelet aggregation. Biochem Biophy Res Commun 1994; 201: 331-9.
25. Usami Y, Fujimura Y, Suzuki M, Ozeki Y, Nishio K, Fukui H, Titani K. Primary structure of two-chain botrocetin; a von Willebrand factor modulator purified from the venom of Bothrops jararaca. Proc Natl Acad Sci USA 1993; 90: 928-32.
26. Drickamer K. Two distinct classes of carbohydrate recognition-domains in animal lectins. J Biol Chem 1988; 263: 9557-60.
27. Giga Y, Ikai A, Takahashi K. The complete amino acid sequence of echinoidin, a lectin from the coelomic fluid of the sea urchin Anthocidaris crassispina. J Biol Chem 1987; 262: 6197-203.
28. 2+-dependent-type lectins. J Biol Chem 1991; 266: 2320-6.
29. Fujimura Y, Titani K, Holland LZ, Russell SR, Roberts JR, Elder JH, Ruggeri ZM, Zimmerman TS. von Willebrand factor. A reduced and alkylated 52/48 kDa fragment beginning at amino acid residue 449 contains the domains interacting with platelet glycoprotein Ib. J Biol Chem 1986; 261: 381-5.
30. Fujimura Y, Usami Y, Titani K, Niinomi K, Nishio K, Takase T, Yoshioka A, Fukui H. Studies on anti-von Willebrand factor (vWF) monoclonal antibody NMC-4 which inhibits both ristocetin- and botrocetin-induced vWF binding to platelet glycoprotein Ib. Blood 1991: 77: 113-20.
31. Azuma H, Hayashi T, Dent JA, Ruggeri ZM, Ware J. Disulfide bond requirements for assembly of the platelet glycoprotein Ib-binding domain of von Willebrand factor. J Biol Chem 1993; 268: 2821-7.
32. Dong Z, Thomas RS, Crimmins DL, McCourt DW, Tuley EA, Sadler JE. Disulfide bonds required to assemble functional von Willebrand factor multimers. J Biol Chem 1994; 269: 6753-8.
33. Fujimura Y, Miyata S, Nishida S, Miura S, Kaneda M, Yoshioka A, Fukui H, Katayama M, Tuddenham EGD, Usami Y, Titani K. The interaction of botrocetin with normal or variant von Willebrand factor (types IIA and IIB) and its inhibition by monoclonal antibodies that block receptor binding. Thromb Haemost 1992; 68: 464-9.
34. Sugimoto M, Mohri H, McClintock RA, Ruggeri ZM. Identification of discontinuous von Willebrand factor sequences involved in complex formation with botrocetin: a model for regulation of von Willebrand factor binding to platelet glycoprotein Ib. J Biol Chem 1991; 266: 18172-8.
35. Sugimoto M, Ricca G, Hrinda ME, Schreiber AB, Searfoss GH, Bottini E, Ruggeri ZM. Functional modulation of the isolated glycoprotein Ib binding domain of von Willebrand factor expressed in Escherichia coli. Biochemistry 1991; 30: 5202-9.
36. Andrews RK, Gorman JJ, Booth WJ, Corino GL, Castaldi PA, Berndt MC. Cross-linking of a monomeric 39/34-kDa dispase fragment of von Willebrand factor (Leu-480/Val481 - Gly-718) to the N-terminal region of the α-chain of membrane glycoprotein Ib on intact platelets with bis (sulfosuccinimidyl) suberate. Biochemistry 1989; 28: 8326-36.
37. Miura S, Fujimura Y, Sugimoto M, Kawasaki Y, Ikeda Y, Titani K, Yoshioka, A. Structural elements influencing von Willebrand factor (vWF) affinity for platelet glycoprotein Ib within a dispase-digested vWF. Blood 1994; 84: 1553-8.
38. Ginsburg D, Sadler JE. von Willebrand disease: a database of point mutations, insertions, and deletions. Thromb Haemost 1993; 69: 177-84.
39. Hubert L, Gaucher C, de Romeuf C, Horellou M-H, Mazurier C. Leu 697→Val mutation in mature von Willebrand factor is responsible for type IIB von Willebrand disease. Blood 1994; 83: 1542-50.
40. Federici AB, Stabile MT, Canciani S, Miyata S, Ware JL. New mutation Ile(546)(Val in a family with type IIB von Willebrand disease characterized by spontaneous platelet aggregation, thrombocytopenia and normal levels of ristocetin cofactor. Thromb Haemost 1995; 73: 1170 (abstract).
41. Mohri H, Fujimura Y, Shima M, Yoshioka A, Houghten RA, Ruggeri ZM, Zimmerman TS. Structure of the von Willebrand factor domain interacting with glycoprotein Ib. J Biol Chem 1988; 263: 17901-4.
42. Berndt MC, Ward CM, Booth WJ, Castaldi PA, Mazurov AV, Andrews RK. Identification of aspartic acid 514 through glutamic acid 542 as a glycoprotein Ib-IX complex receptor recognition sequence. Mechanisms of modulation of von Willebrand factor by ristocetin and botrocetin. Biochemistry 1992; 31: 11144-51.
43. Sobel M, Sobel DF, Kermode JC, Harris RB. Localization and characterization of a heparin binding domain peptide of human von Willebrand factor. J Biol Chem 1992; 267: 8857-62.
44. Christophe O, Obert B, Meyer D, Girma J-P. The binding domain of von Willebrand factor to sulfatides is distinct from those interacting with glycoprotein Ib, heparin, and collagen and resides between amino acid residues Leu512 and Lys673. Blood 1991; 78: 2310-7.
45. Makita K, Miura S, Shimoyama T, Narita N, Sakurai T, Sugimoto M, Yoshioka A, Titani K, Ruggeri ZM, Fujimura Y. Characterization of murine anti-botrocetin monoclonal antibodies. Int J Haematol 1995; 61: 276 (Abstract).
46. Vicente V, Houghten RA, Ruggeri ZM. Identification of a site in the alpha chain of platelet glycoprotein Ib that participates in von Willebrand factor binding. J Biol Chem 1990; 265: 274-80.
47. Katagiri Y, Hayashi Y, Yamamoto K, Tanoue K, Kosaki G, Yamazaki H. Localization of von Willebrand factor and thrombin-interactive domains on human platelet glycoprotein GPIb. Thromb Haemost 1990; 63: 122-6.
48. Dong J-F, Li CQ, Lopez JA. Tyrosine sulfation of the glycoprotein Ib-IX complex: identification of sulfated residues and effect on ligand binding. Biochemistry 1994, 33: 13946-53.
49. Marchese P, Murata M, Mazzucatto M, Pradella P, De Marco L, Ware J, Ruggeri ZM. Identification of three tyrosine residues of glycoprotein Ibα with distinct roles in von Willebrand factor and α-thrombin binding. J Biol Chem 1995, 270: 9571-8.
50. Ward CM, Andrews RK, Smith AI, Berndt MC. Mocarhagin, a novel cobra venom metalloprotease, cleaves the platelet von Willebrand factor receptor glycoprotein Ibα. Identification of the sulfated tyrosine/anionic sequence Tyr276-Glu282 of glycoprotein Ibα as a binding site for von Willebrand factor and α-thrombin. Biochemistry 1996, 35: 4929-38.
51. Scarborough RM, Hsu MA, Teng W, Nannizzi L, Rose JW. Purification and characterization of potent inhibitors of von Willebrand factor binding to glycoprotein (GP)Ib from the venom of the timber rattlesnake, Crotalus h. horridus. Blood 1991; 78: 1568 (abstract).
52. Peng M, Lu W, Kirby EP. Alboaggregin-B: a new platelet agonist that binds to platelet membrane glycoprotein Ib. Biochemistry 1991; 30: 11529-36.
53. Peng M, Lu W, Kirby EP. Characterization of three alboaggregins purified from Trimeresurus alborablis venom. Thromb Haemost 1992; 67: 702-7.
54. Yoshida E, Fujimura Y, Miura S, Sugimoto M, Fukui H, Narita N, Usami Y, Suzuki M, Titani K. Alboaggregin-B and botrocetin, two snake venom proteins with highly homologous amino acid sequences but totally distinct functions on von Willebrand factor binding to platelets. Biochem Biophy Res Commun 1993; 1386-92.
55. Usami Y, Suzuki M, Yoshida E, Sakurai Y, Hirano K, Kawasaki T, Fujimura Y, Titani K. Primary structure of alboaggregin-B purified from the venom of Trimeresurus alborablis. Biochem Biophys Res Comm 1996; 219: 727-33.
56. Peng M, Lu W, Beviglia L, Niewiarowski S, Kirby EP. Echicetin: a snake venom protein that inhibits binding of von Willebrand factor and alboaggregins to platelet glycoprotein Ib. Blood 1993; 81: 2321-8.
57. Chen Y-L, Tsai I-H. Functional and sequence characterization of agkicetin, a new glycoprotein Ib antagonist isolated from Agkistrodon acutus venom. Biochem Biophys Res Commun 1995; 210: 472-7.
58. Peng M, Holt JC, Niewiarowski S. Isolation, characterization and amino acid sequence of echicetin β subunit, a specific inhibitor to von Willebrand factor and thrombin interaction with glycoprotein Ib. Biochem Biophys Res Commun 1994; 205: 68-72.
59. Fujimura Y, Ikeda Y, Miura S, Yoshida E, Shima H, Nishida S, Suzuki M, Titani K, Taniuchi Y, Kawasaki T. Isolation and characterization of jararaca GPIb-BP, a snake venom antagonist specific to platelet glycoprotein Ib. Thromb Haemost 1995; 74: 743-50.
60. Taniuchi Y, Kawasaki T, Fujimura Y, Suzuki M, Titani K, Sakai Y, Kaku S, Hisamichi N, Satoh N, Takenaka T, Handa M, Sawai Y. Flavocetin-A and -B, two high molecular mass glycoprotein Ib binding proteins with high affinity purified from Trimeresurus flavoviridis venom, inhibit platelet aggregation at high shear stress. Biochem Biophys Acta 1995; 1244: 331-8.
61. Kawasaki T, Taniuchi Y, Hisamichi N, Fujimura Y, Suzuki M, Titani K, Kaku S, Satoh N, Takenaka T, Handa M, Sawai Y. Tokaracetin, a new platelet antagonist that binds to platelet glycoprotein Ib and inhibits von Willebrand factor- dependent shear-induced platelet aggregation. Biochem J 1995; 308: 947-53.
62. Kawasaki T, Fujimura Y, Usami Y, Suzuki M, Miura S, Sakurai Y, Makita K, Taniuchi Y, Hirano K, Titani K. Complete amino acid sequence and identification of the platelet glycoprotein Ib binding site of jararaca GPIb-BP, a snake venom protein isolated from Bothrops jararaca. J Biol Chem 1996; 271: 10635-9.