Dynamic aspects of glutathione and nitric oxide metabolism in endotoxemic rats

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 271, Issue 4 34-4, 1996, Pages

  Minamiyama, Yukiko ^a   Takemura, Shigekazu ^a   Koyama, Keiko ^a   Yu, Hidenori ^a   Miyamoto, Masafumi ^a   Inoue, Masayasu ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

endotoxin; S nitrosothiols

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; GLUTATHIONE; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ARTICLE; DETOXIFICATION; ENDOTOXEMIA; ENZYME INHIBITION; GLUTATHIONE METABOLISM; LIVER METABOLISM; MALE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RAT;

EID: 0029862130     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1996.271.4.g575     Document Type: Article

References (33)

1. - donation by S-nitrosothiols: implications for regulation of physiological functions by S-nitrosylation and acceleration of disulflde formation. Arch. Biochem. Biophys. 318: 279-285, 1995.
2. Beck, L., V. W. Linkenheimer, and A. Marracini. Effects of tumbling trauma, scalding and hemorrhage on rat tissue nonprotein sulfhydryl. Proc. Soc Exp. Biol. Med. 86: 823-827, 1954.
3. Billiar, T. R., R. D. Curran, D. J. Stuehr, M. A. West, B. G. Bentz, and R. L. Simmons. An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro. J. Exp. Med. 169: 1467-1472, 1989.
4. Burkart, V., Y. Imai, B. Kallmann, and H. Kalb. Cyclosporin A protects pancreatic islet cells from nitric oxide-dependent macrophage cytotoxicity. FEBS Lett. 313: 56-58, 1992.
5. Ellman, G. L. Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82: 70-77, 1959.
6. Falsini, S., M. P. Cellai, P. Angiolini, M. Cavuta, and G. P. Novelli. Reduced glutathione and L-cysteine in endotoxic shock in the rat. Minerva Anesthesiol. 60: 413-418, 1994.
7. 15N]nitrate in biological fluids. Anal. Biochem. 126: 131-138, 1982.
8. Hart, T. W. Some observations concerning the S-nitroso and S-phenylsulphonyl derivatives of L-cysteine and glutathione. Tetrahedron Lett. 26: 2013-2016, 1985.
9. Hirata, E., and H. Takahashi. Degradation of methyl mercury glutathione by the pancreatic enzymes in bile. Toxicol. Appl. Pharmacol. 58: 483-491, 1981.
10. Inoue, M. Protective mechanism against reactive oxygen species. In: The Liver: Biology and Pathobiology (3rd ed.), edited by I. M. Arias, J. L. Boyer, N Fausto, D. A. Jakoby, D. Schachter, and D. A. Shafritz. New York: Raven, 1994, p. 443-459.
11. Inoue, M., R. Kinne, T. Tran, and I. M. Arias. Taurocholate transport by rat liver sinusoidal membrane vesicles: evidence of sodium cotransport. Hepatology 2: 572-579, 1982.
12. Inoue, M., R. Kinne, T. T. Tran, L. Biempica, and I. M. Arias. Rat liver canalicular membrane vesicles: isolation and topological characterization. J. Biol. Chem. 258: 5183-5188, 1983.
13. Inoue, M., and Y. Morino. Inactivation of renal γ-glutamyl transpeptidase by 6-diazo-5-oxo-L-nor-leucylglycine, an inactive precursor of affinity labeling reagent. Proc. Natl. Acad. Sci. USA 78: 46-49, 1981.
14. Inoue, M., S. Shinozuka, and Y. Morino. Mechanism of renal peritubular extraction of plasma glutathione. Eur. J. Biochem. 157: 605-609, 1986.
15. Irita, K., H. Okabe, A. Koga, K. Kurosawa, K. Tagawa, M. Yamakawa, J. Yoshitake, and S. Takahashi. Increased sinusoidal efflux of reduced and oxidized glutathione in rats with endotoxin/D-galactosamine hepatitis. Circ. Shock 42: 115-120, 1994.
16. Jaeschke, H. Enhanced sinusoidal glutathione efflux during endotoxin-induced oxidant stress in vivo. Am. J. Physiol. 263 (Gastrointest. Liver Physiol. 26): G60-G68, 1992.
17. Kida, T., T. Kuroki, K. Kobayashi, and M. Inoue. Role of vascular nitric oxide synthase in endotoxin shock of Propionibacterium acnes-sensitized rats. Arch. Biochem. Biophys. 312: 135-141, 1994.
18. Lauterburg, B. H., J. D. Adams, and J. R. Mitchell. Hepatic glutathione horneostasis in the rat: efflux accounts for glutathione turnover. Hepatology 4: 586-590, 1984.
19. Liu, P., M. A. Fisher., A. Farhood, C. W. Smith, and H. Jaeschke. Beneficial effects of extracellular glutathione against endotoxin-induced liver injury during ischemia and reperfusion. Circ. Shock 43: 64-70, 1994
20. Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193: 265-275, 1951.
21. Meister, A. Glutathione. In: The Liver: Biology and Pathobiology (2nd ed), edited by I. M. Arias, W. B. Jacoby, H. Popper, D. Schachter, and D. A. Shafritz. New York: Raven, 1988, p. 401-417.
22. Mitchell, J. A., H. Sheng, U. Förstermann, and F. Murad. Characterization of NO synthase in non-adrenergic nerve containing tissue from the rat anococcygeus muscle. Br. J. Pharmacol. 104: 289-291, 1991.
23. Okabe, H., K. Irita, K. Kurosawa, K. Tagawa, A. Koga, M. Yamakawa, J. Yoshitake, and S. Takahashi. Increase in the plasma concentration of reduced glutathione observed in rats with liver damage induced by lipopolysaccharide/D-galactosamine: effects of ulinastatin, a urinary trypsin inhibitor. Circ. Shock 41: 268-272, 1993.
24. Okabe, H., K. Irita, S. Taniguchi, K. Kurosawa, K. Tagawa, J. Yoshitake, and S. Takahashi. Endotoxin causes early changes in glutathione concentrations in rabbit plasma and liver. J. Surg. Res. 57: 416-419, 1994.
25. Saville, B. A scheme for colorimetric determination of microgram amounts of thiols. Analysis 83: 670-672, 1958.
26. Scharfstein, J. S., J. F. Keaney, Jr., A. Slivka, G. N. Welch, J. A. Vita, J. S. Stamler, and J. Loscalzo. In vivo transfer of nitric oxide between a plasma protein-bound reservoir and low molecular weight thiols. J. Clin. Invest. 94: 1432-1439, 1994.
27. Stander, J. S. Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell 78: 931-936, 1994.
28. Stamler, J. S., D. J. Singel, and J. Loscalzo. Biochemistry of nitric oxide and its redox-activated forms. Science Wash. DC 258: 1898-1902, 1992.
29. Sugino, K., K. Dohi, K. Yamada, and T. Kawasaki. Changes in the levels of endogenous antioxidants in the liver of mice with experimental endotoxemia and the protective effects of the antioxidanis. Surgery St. Louis 105: 200-206, 1989.
30. Szabo, C., J. A. Mitchell, C. Thiemermann, and J. R. Vane. Nitric oxide mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock. Br. J. Pharmacol. 108: 786-792, 1993.
31. Tietze, F. Enzymic method for quantitative determination of nanogram amounts of total, and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 27: 502-522, 1969.
32. Wang, Y., W. R. Mathews, D. M. Guido, A. Farhood, and H. Jaeschke. Inhibition of nitric oxide synthesis aggravates perfusion injury after hepatic ischemia and endotoxemia. Shock 4: 282-288, 1995.
33. Zhang, H., H. Spapen, D. N. Nguyen, M. Benlabed, W. A. Buurman, and J. L. Vincent. Protective effects of N-acetyl-L-cysteine in endotoxemia. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H1746-H1754, 1994.