The mechanism of β-glycerophosphate action in mineralizing chick limb-bud mesenchymal cell cultures

Journal of Bone and Mineral Research

Volumn 11, Issue 11, 1996, Pages 1694-1702

  Boskey, Adele L ^a,d   Guidon, Peter ^b   Doty, Stephen B ^a   Stiner, Dalina ^a   Leboy, Phoebe ^c   Binderman, Itzhak ^a  

^a Department of Obstetrics Gynecology   (United States)

^b SETON HALL UNIVERSITY   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; GLYCEROL 2 PHOSPHATE; PHOSPHATE; PHOSPHOPROTEIN PHOSPHATASE;

ANIMAL TISSUE; ARTICLE; BONE MINERALIZATION; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; ENZYME INHIBITION; INFRARED SPECTROSCOPY; LIMB BUD; MESENCHYME CELL; NONHUMAN; OSSIFICATION;

EID: 0029861933     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.5650111113     Document Type: Article

References (46)

1. Ashton BA, Bromley L 1986 The influence of β-glycerophosphate on osteoblast-like cell lines. Bone 7:305-306.
2. Bellows CG, Aubin JE, Heersche JNM 1991 Initiation and progression of mineralization of bone nodules formed in vitro: The role of alkaline phosphatase and organic phosphate. Bone Miner 14:27-40.
3. c-src kinase. Bone Miner 18:91-106.
4. Berry L, Shuttleworth CA 1989 Expression of the chondrogenic phenotype by mineralizing cultures of embryonic chick calvarial bone cells. Bone Miner 7:31-45.
5. Gerstenfeld LC, Landis WJ 1991 Gene expression and extracellular matrix ultrastructure of a mineralizing chondrocyte cell culture system. J Cell Biol 112:501-513.
6. Sakamoto S, Sakamoto M, Goldberg L, Colarusso L, Gotoh Y 1989 Mineralization induced by beta-glycerophosphate in cultures leads to a marked increase in collagenase synthesis by mouse osteogenic MC3T3-E1 cells under subsequent stimulation with heparin. Biochem Biophys Res Commun 162:773-780.
7. Tenenbaum HC 1987 Levamisole and inorganic pyrophosphate inhibit β-glycerophosphate induced mineralization of bone formed in vitro. Bone Miner 3:13-26.
8. Tenenbaum H, McCulloch CAG, Fair C, Birek C 1989 Stimulatory effect of phosphates on bone metabolism in vitro. Cell Tissue Res 257:555-563.
9. Tenenbaum HC, Limeback H, McCulloch CAG, Mamujee H, Sukhu B, Torontali M 1987 Osteogenic-phase specific co-regulation of collagen synthesis and mineralization by β-glycerophosphate in chick periosteal cultures. Bone 12:129-138.
10. Iwamoto M, Shapiro I, Yagami K, Boskey AL, Leboy P, Adams S, Pacifici M 1993 Retinoic acid induces rapid mineralization and expression of mineralization-related genes in chondrocytes. Exp Cell Res 207:413-420.
11. Gerstenfeld, Landis WJ 1991 Gene expression and extracellular matrix ultrastructure of a mineralizing chondrocyte cell culture system. J Cell Biol 112:501-513.
12. Khouya HI, Bevington A, Kemp GJ, Russell RGG 1990 Calcium and Orthophosphate deposition in vitro do not imply osteoblast-mediated mineralization: Mineralization by beta-glycerophosphate in the absence of osteoblasts. Bone 11:385-392.
13. Boskey AL, Stiner D, Leboy P, Doty S, Binderman I 1992 Optimal conditions for cartilage calcification in differentiating chick limb-bud mesenchymal cells. Bone Miner 16:11-37.
14. Boskey AL, Camacho NP, Mendelsohn R, Doty SB, Binderman I 1992 FT-IR microscopic mappings of early mineralization in chick limb bud mesenchymal cell cultures. Calcif Tissue Int 51:443-448.
15. Ahrens PBA, Solursh M, Reiter RS 1977 Stage related capacity for limb chondrogenesis in cell culture. Dev Biol 60:69-82.
16. Hamburger V, Hamilton HL 1951 A series of normal stages in the development of the chick embryo. J Morphol 88:49-92.
17. Boskey AL, Doty SB, Mendelsohn R, Binderman I 1994 ATP promotes mineralization in differentiating chick limb-bud mesenchymal cell cultures. Microsc Res Technique 28:492-504.
18. Litchfield DW, Lozeman FJ, Piening C, Sommercorn J, Takio K, Walsh KA, Krebs EG 1990 Subunit structure of casein kinase II from bovine testis. J Biol Chem 265:7638-7644.
19. Marin O, Meggio F, Marchiori F, Boring G, Pinna LA 1990 Site specificity of casein kinase-2 (TS) from rat liver cytosol. Eur J Biochem 160:239-244.
20. Edleman AM, Blumenthal DK, Krebs EG 1987 Protein serine/ threonine kinases. Ann Rev Biochem 56:567-613.
21. Boskey AL, Dick B 1991 The effect of phosphatidylserine on in vitro hydroxyapatite growth proliferation. Calcif Tissue Int 49:193-196.
22. Willis JB 1960 The determination of metals in blood serum by atomic absorption spectroscopy. I Calcium Spectrochem Acta 16:259-272.
23. Heinonen JK, Lahti RJ 1981 A new and convenient calorimetric determination of inorganic orthophosphate and its application to the assay of inorganic pyrophosphates. Anal Biochem 113:313-317.
24. Kim YJ, Sah RLY, Doong JYH, Grodzinsky AJ 1988 Fluor-metric assay of DNA in cartilage explants using Hoechst 33258. Anal Biochem 174:168-165.
25. Gadaleta SJ, Paschalis EP, Betts F, Mendelsohn R, Boskey AL 1996 Fourier transform infrared spectroscopy of the solution mediated conversion of amorphous calcium phosphate to hydroxyapatite: New correlations between x-ray diffraction to infrared data. Calcif Tissue Int 58:9-16.
26. Leboy PS, Shapiro IM, Uschmann BD, Oshima O, Lin D 1988 Gene expression in mineralizing chick epiphyseal cartilage. J Cell Biol 263:8515-8520.
27. Leboy PS, Vaias L, Uschmann BD, Golub EE, Adams SL, Pacifici M 1989 Ascorbic acid induces alkaline phosphatase, type X collagen and calcium deposition in cultured chick chondrocytes. J Biol Chem 264:17281-17286.
28. Mikuni-Takagaki Y, Glimcher MJ 1990a Post-translational processing of chicken bone phosphoproteins: Identification of bone (phospho)protein kinase. Biochem J 268:593-597.
29. Mikuni-Takagaki Y, Glimcher MJ 1990b Post-translational processing of chicken bone phosphoproteins: Identification of the bone phosphoproteins of embryonic tibia. Biochem J 268:585-591.
30. Wu CB, Pelech S, Veis A 1992 The in vitro phosphorylation of the native rat incisor phosphophoryn. J Biol Chem 267:16588-16594.
31. Sfeir C, Veis A 1995 Casein kinase localization in the endoplasmic reticulum of the ROS17/2.8 cell line. J Bone Miner Res 10:607-615.
32. Ackerman P, Glover CVC, Osheroff N 1990 Stimulation of casein kinase II by epidermal growth factor: Relationship between the physiological activity of the kinase and the phosphorylation state of its β subunit. Proc Natl Acad Sci USA 87:821-825.
33. Harrison G, Shapiro IM, Golub EE 1995 The phosphatidylinositol-glycolipid anchor on alkaline phosphatase facilitates mineralization initiation in vitro. J Bone Miner Res 10:568-573.
34. Gronowicz G, Woodiel FN, McCarthy MB, Raisz LG 1989 In vitro mineralization of fetal rat parietal bones in defined serum-free medium: Effect of β-glycerol phosphate. J Bone Miner Res 4:313-324.
35. Fallon MD, Whyte MP, Teitelbaum SL 1980 Stereospecific inhibition of alkaline phosphatase by L-tetramisole prevents in vitro cartilage calcification. Lab Invest 43:489-494.
36. Lee KL, Aubin JE, Heersche, JNM 1993 β-glycerophosphate-induced mineralization of osteoid does not alter expression of extracellular matrix components in fetal rat calvarial cell cultures. J Bone Miner Res 7:1211-1219.
37. Gerstenfeld LC, Chipman SD, Glowacki J, Lian JB 1987 10 mM β-GP had no effect on proliferation, type I or osteocalcin protein. Dev Biol 122:49-60.
38. Asahina I, Sampath TK, Nishimura I, Hauschka PV 1993 β-GP (+asc) elevates osteocalcin protein in calvarial preosteoblasts compared to asc alone. J Cell Biol 123:921-933.
39. Thomas JT, Boot-Handford RP, Grant ME 1990 Modulation of type X collagen gene expression by calcium β-glycerophosphate and levamisole: Implications for a possible role for type X collagen in endochondral bone formation. J Cell Sci 95:639-648.
40. Alini M, Carey D, Hirata S, Grynpass MD, Pidoux I, Poole AR 1994 Cellular and matrix changes before and at the time of calcification in the growth plate studied in vitro: Arrest of type X collagen synthesis and net loss of collagen when calcification is initiated. J Bone Miner Res 9:1077-1087.
41. Cancedda D, Gentili C, Manduca P, Cancedda R 1992 No major differences in secreted proteins with or without β-GP. J Cell Biol 117:427-435.
42. Bonen DK, Kuettner KE, Schmid TM 1991 β-glycerophosphate does not induce type X collagen synthesis in chondrocyte culture: Mineral accumulation does. Transactions Combined Meeting Orthopaedic Research Societies, USA, Japan, Canada, p. 132.
43. Schmid TM, Cole AA, Chen Q, Bonen DK, Luchene L, Linsenmeyer TF 1994 Assembly of Type X Collagen by Hypertrophic Chondrocytes, in Extracellular Matrix Assembly and Structure. Academic Press, New York, NY, U.S.A., pp. 171-206.
44. Ulloa L, Diaz-Nido J, Avila J 1993 Depletion of casein kinase II by antisense oligonucleotide prevents neuritogenesis in neuroblastoma cells. EMBO J 12:1633-1640.
45. Simkowski KW, Tao M 1980 Studies on a soluble human erythrocyte protein kinase. J Biol Chem 255:6456-6461.
46. Burch WM, Hammer G, Wuthier RE 1985 Phosphotyrosine and phosphoprotein phosphatase activity of alkaline phosphatase in mineralizing cartilage. Metabolism 34:169-175.