Developmental expression of murine β-trace in embryos and adult animals suggests a function in maturation and maintenance of blood-tissue barriers

Developmental Dynamics

Volumn 207, Issue 3, 1996, Pages 332-343

  Hoffmann, Andrea ^a   Bächner, Dietmar ^a   Betat, Nicole ^a   Lauber, Jörg ^a   Gross, Gerhard ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Blood tissue barriers; Embryogenesis; In situ hybridization; Leptomeninges; Testis

Indexed keywords

BETA TRACE PROTEIN; SECRETORY PROTEIN; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN CELL; CENTRAL NERVOUS SYSTEM; CHOROID PLEXUS; CILIARY BODY EPITHELIUM; COCHLEA DUCT; EMBRYO; EMBRYO DEVELOPMENT; EPIDIDYMIS; GENE EXPRESSION; LEPTOMENINX; LEYDIG CELL; MESENCHYME CELL; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PERMEABILITY BARRIER; PIGMENT EPITHELIUM; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSE ORGAN; TESTIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BETA-GLOBULINS; BLOOD-BRAIN BARRIER; BLOOD-RETINAL BARRIER; BLOOD-TESTIS BARRIER; CLONING, MOLECULAR; DNA, COMPLEMENTARY; EMBRYO; FEMALE; GENE EXPRESSION; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MICE; MOLECULAR SEQUENCE DATA; PREGNANCY; RNA; SEQUENCE HOMOLOGY, AMINO ACID;

ANIMALIA; MURINAE;

EID: 0029861447     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0177(199611)207:3<332::AID-AJA10>3.0.CO;2-6     Document Type: Article

References (33)

1. 1 in human cerebrospinal fluid. Prostaglandins 17:405-409.
2. 3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineages. DNA Cell Biol. 12:871-880.
3. Bächner, D., Manca, A., Steinbach, P., Wöhrle, D., Just, W., Vogel, W., Hameister, H., and Poustka, A. (1993) Enhanced expression of the murine FMR1 gene during germ cell proliferation suggests a special function in both the male and the female gonad. Hum. Mol. Genet. 2:2043-2050.
4. Cox, K.H., DeLeon, D.V., Angerer, L.M., and Angerer, R.C (1984) Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes. Dev. Biol. 101:485-502.
5. 4 synthesis by antigen-presenting cells that migrate to the central nervous system. Neurology 41:322-324.
6. Goh, H., Urade, Y., Fujimoto, N., and Hayaishi, O. (1987) Content and formation of prostaglandins and distribution of prostaglandin-related enzyme activities in the rat ocular system. Biochim. Biophys. Acta 921:302-311.
7. Harrington, M.G., Aebersold, R., Martin, B.M., Merril, C.R., and Hood, L. (1993) Identification of a brain-specific human cerebrospinal fluid glycoprotein, beta-trace protein. Appl. Theor. Electrophor. 3:229-234.
8. Hartmann, C., Felgenhauer, K., and Haussen, C. (1983) Filtration und lokale Synthese von Proteinen im Kammerwasser and Liquor cerebrospinalis. Fortschr. Ophthalmol. 80:103-107.
9. Hochwald, G.M., Pepe, A.J., and Thorbecke, G.J. (1967) Trace Proteins in biological fluids. IV. Physicochemical properties and sites of formation of χ-trace and β-trace proteins. Proc. Soc. Exp. Biol. Med. 124:961-966.
10. Hoffmann, A., Conradt, H.S., Gross, G., Nimtz, M., Lottspeich, F., and Wurster, U. (1993) Purification and chemical characterization of β-trace protein from human cerebrospinal fluid: Its identification as prostaglandin D synthase. J. Neurochem. 61:451-456.
11. Hoffmann, A., Nimtz, M., Wurster, U., and Conradt, H.S. (1994) Carbohydrate structures of β-trace protein from human cerebrospinal fluid: Evidence for "brain-type" N-glycosylation. J. Neurochem. 63: 2185-2196.
12. Hoffmann, A., Gath, U., Gross, G., Lauber, J., Getzlaff, R., Hellwig, S., Galla, H.-J., and Conradt, H.S. (1996) Constitutive Secretion of beta-trace protein by cultivated porcine choroid plexus epithelial cells: Elucidation of its complete amino acid and cdna sequences. J. Cell. Physiol. (in press).
13. Igarashi, M., Nagata, A., Toh, H., Urade, Y., and Hayaishi, O. (1992) Structural organization of the gene for prostaglandin D synthase in the rat brain. Proc. Natl. Acad. Sci. USA 89:5376-5380
14. Killian, G.J., Chapman, D.A., and Rogowski, L.A. (1993) Fertility-associated proteins in Holstein bull seminal plasma. Biol. Reprod. 49:1202-1207.
15. Kuruvilla, A.P., Hochwald, G.M., Ghiso, J., Castaño, E.M., Pizzolato, M., and Frangione, B. (1991) Isolation and amino terminal sequence of β-trace, a novel protein from human cerebrospinal fluid. Brain Res. 565:337-340.
16. Link, H. (1967) Immunoglobulin G and low-molecular-weight proteins in human cerebrospinal fluid. Acte Neurol. Scand. 43(Suppl. 28):1-136.
17. Nagata, A., Suzuki, Y., Igarashi, M., Eguchi, N., Toh, H., Urade, Y., and Hayaishi, O. (1991) Human bran prostaglandin D synthase has been evolutionarily differentiated from lipophilic ligand-carrier proteins. Proc. Natl. Acad. Sci. USA 88:4020-4024.
18. Olsson, J.-E. (1975) Correlation between the concentration of beta-trace protein and the number of spermatozoa in human semen. J. Reprod. Fertil. 42:149-151.
19. Olsson, J.-E., and Nord, L. (1973) Immunochemical and immunofluorescence studies of beta-trace protein in different species and organs, with special reference to the central nervous system. J. Neurochem. 21:625-633.
20. Olsson, J.-E., and Sandberg, M. (1975) Demonstration of synthesis of beta-trace protein in different tissues of squirrel monkey. Neurobiology 5:270-276.
21. Olsson, J.-E., Blomstrand, C., Haglid, K.G. (1974) Cellular distribution of beta-trace protein in CNS and brain tumours. J. Neurol. Neurosurg. Psychiatr. 37:302-311.
22. Penny, R., and Osserman, E.F. (1971) Studies on beta-trace protein. Aust. J. Exp. Biol. Med. Sci. 49:111-120.
23. Pervaiz, S., and Brew, K. (1987) Homology and structure-function correlations between 1-acid glycoprotein and serum retinol-binding protein and its relatives. FASEB J. 1:209-214.
24. Rosen, B., and Beddington, R.S.P. (1993) Whole mount in situ hybridization in the mouse embryo: Gene expression in three dimensions. Trends Genet. 9:162-167.
25. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) "Molecular Cloning: A Laboratory Manual," 2nd Ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
26. Sanger, F., Nicklen, S., and Coulson, A.R. (1977) DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74: 6463-5467.
27. Tachibana, M., Fe, J., Urade, Y., and Hayaishi, O. (1987) Brain-type prostaglandin D synthase occurs in the rat cochlea. Proc. Natl. Acad. Sci. USA 84:7677-7680.
28. Tautz, D., and Pfeifle, C. (1989) A nonradioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98:81-85.
29. 2 formation and characterization of its synthetases in various tissues of adult rats. Arch. Biochem. Biophys. 260:521-531.
30. Urade, Y., Kitahama, K., Ohishi, H., Kaneko, T., Mizuno, N., and Hayaishi, O. (1993) Dominant expression of mRNA for prostaglandin D synthase in leptomeninges, choroid plexus, and oligodendrocytes of the adult rat brain. Proc. Natl. Acad. Sci. USA 90:9070-9074.
31. 65 as an essential thiol. J. Biol. Chem. 270:1422-1428.
32. Watanabe, K., Urade, Y., Mäder, M., Murphy, C., and Hayaishi, O. (1994) Identification of β-trace as prostaglandin D synthase. Biochem. Biophys. Res. Commun. 203:1110-1116.
33. 2 synthase. J. Biol. Chem. 267:23202-23206.