Vitamin K status and bone mass in women with and without aortic atherosclerosis: A population-based study

Calcified Tissue International

Volumn 59, Issue 5, 1996, Pages 352-356

  Jie, K S G ^a   Bots, M L ^b   Vermeer, C ^a   Witteman, J C M ^b   Grobbee, D E ^b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Atherosclerosis; Bone mass; Calcification; Gammacarboxyglutamate; Osteocalcin; Vitamin K

Indexed keywords

4 CARBOXYGLUTAMIC ACID; OSTEOCALCIN; VITAMIN K GROUP;

ABDOMINAL AORTA; AORTA ATHEROSCLEROSIS; ARTERY CALCIFICATION; ARTICLE; BONE MASS; BONE MINERALIZATION; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; OSSIFICATION; OSTEOPOROSIS; POSTMENOPAUSE; PRIORITY JOURNAL; VITAMIN K DEFICIENCY;

AGED; AORTA; ARTERIOSCLEROSIS; BONE DENSITY; COHORT STUDIES; FEMALE; HUMANS; MIDDLE AGED; OSTEOCALCIN; OSTEOPOROSIS; POSTMENOPAUSE; RISK FACTORS; VITAMIN K;

EID: 0029861325     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002239900139     Document Type: Article

References (46)

1. Stevenson JC (1990) Osteoporosis and cardiovascular disease in women: converging path? Lancet 336:1121-1122
2. Orimo H, Terashita K, Nakamura T, Ohshima J (1985) Ca and atherosclerosis. J Nutr Sci Vitaminol 31(suppl):S33-S36
3. Fujita T, Okamoto Y, Sakagami Y, Kiichiro O, Ohata M, (1984) Bone changes and aortic calcification in aging inhabitants of mountain versus seacoast communities in the Kii peninsula. J Am Soc Geriatric Soc 32:124-128
4. Browner WS, Seeley DG, Vogt TM, Cummings SR (1991) Non-trauma mortality in elderly women with low bone mineral density. Lancet 338:335-338
5. Demer LL, Watson KE, Boström K (1994) Mechanism of calcification in atherosclerosis. Trends Cardiovasc Med 4:45-49
6. Price PA, Otsuka AS, Poser JW, Kristaponis J, Raman N (1976) Characterization of a gammacarboxyglutamic acid-containing protein form bone. Proc Natl Acad Sci USA 73: 1447-1451
7. Gallop PM, Lian JB, Hauschka PV (1980) Carboxylated calcium-binding proteins and vitamin K. N Engl J Med 302: 1460-1466
8. Levy RJ, Gundberg C, Scheinman R (1983) The identification of the vitamin K-dependent bone protein osteocalcin as one of the γ-carboxyglutamatic acids containing proteins present in calcified atherosclerotic plaque and mineralized heart valves. Atherosclerosis 46:49-56
9. Shanahan CM, Cary NRB, Metcalfe JC, Weissberg PL (1994) High expression of genes for calcification-regulation proteins in human atherosclerotic plaques. J Clin Invest 93:2393-2402
10. Vermeer C (1990) Gamma-carboxyglutamate-containing proteins and the vitamin K-dependent carboxylase. Biochem J 266:625-636
11. Price PA, Williamson MK, Lothringer JW (1981) Origin of the vitamin K-dependent bone protein found in plasma and its clearance by kidney and bone. J Biol Chem 256:12760-12766
12. Knapen MHJ, Hamulyák K, Vermeer C (1989) The effect of vitamin K supplementation on circulating osteocalcin (bone Gla-protein) and urinary calcium excretion. Ann Int Med 111: 1001-1005
13. Jie K-SG, Gijsbers BLMG, Knapen MHJ, Hamulyak K, Frank HL, Vermeer C (1993) Effects of vitamin K and oral anticoagulants on urinary calcium excretion. Br J Haematol 83:100-104
14. Knapen MHJ, Jie K-SG, Hamulyak K, Vermeer C (1993) Vitamin K-induced changes in markers for osteoblast activity and urinary calcium loss. Calcif Tissue Int 53:81-85
15. Akiba T, Kurihara S, Tachibana K, Kuwahara M, Sakamoto H, Yoneshima H, Marumo F (1991) Vitamin K increased bone mass in hemodialysis patients with low-turnover bone disease. J Am Soc Nephrol 2:608
16. 3. J Bone Miner Res 7:S122
17. Witteman JCM, Grobbee DE, Kok FJ, Hofman A, Valkenburg HA (1989) Increased risk of atherosclerosis in women after the menopause. Br Med J 298:642-644
18. Witteman JCM, Kok FJ, van Saase JLCM, Valkenburg HA (1986) Aortic calcification as a predictor of cardiovascular mortality. Lancet ii:1120-1122
19. Eggen DA (1968) Relationship of calcified lesions to clinically significant atherosclerotic lesions. Ann NY Acad Sci 149:752-767
20. Jie K-SG, Bots ML, Vermeer C, Witteman JCM, Grobbee DE (1995) Vitamin K intake and osteocalcin levels in women with and without aortic atherosclerosis: a population-based study. Atherosclerosis 116:117-123
21. Hoes AW, Grobbee DE, Valdenburg HA, Lubsen J, Hofman A (1993) Cardiovascular risk and all-cause mortality. A twelve-year follow-up study in The Netherlands. Eur J Epidemiol 9:285-292
22. Witteman JCM, Grobbee DE, Valkenburg HA, van Hemert AM, Stijnen T, Hofman A (1993) Cigarette smoking and the development and progression of aortic atherosclerosis. A 9-year population-based follow-up study in women. Circulation 88:2156-2162
23. Johnston CC Jr (1983) Noninvasive methods for quantitating appendicular bone mass. In: Avioli LV (ed) The osteoporotic syndrome. Orlando, Florida, Grune & Stratton, pp 73-84
24. Löwik MRH, Schrijver J, Odink J, van den Berg H, Wedel M, Hermus RJJ (1990) Nutrition and aging: nutritional status of "apparently healthy" elderly. J Am Coll Nutr 9:18-27
25. Ooms ME (1994) Osteoporosis in elderly women [thesis]. Amsterdam, Vrije Universiteit
26. Hyman JB, Epstein JH (1954) A study of the correlation between roentgenographic and post-mortem calcification of the aorta. Am Heart J 47:540
27. Witteman JCM, Grobbee DE, Valkenburg HA, van Hemert AM, Stijnen T, Burger H, Hofman A (1994) J-Shaped relation between change in diastolic blood pressure and progression of aortic atherosclerosis. Lancet 343:504-507
28. Witteman JCM, Kannel WB, Grobbee DE, et al. (1990) Aortic calcification plaques and cardiovascular disease. (The Framingham Study). Am J Cardiol 66:1060-1064
29. Siitonen O, Uusitupa M, Pyörälä K, et al. (1987) Aortic calcifications and their relationship to coronary heart disease and cardiovascular risk factors in patients with newly diagnosed non-insulin-dependent diabetes and in non-diabetic subjects. Cardiology 74:335-339
30. Johnston CC, Longcope C (1990) Premenopausal bone loss, a risk factor for osteoporosis. N Engl J Med 323:1271-1272
31. Wasnich R (1993) Bone mass measurement: prediction of risk. Am J Med 95 (suppl 5A):6S-10S
32. Szulc P, Chapuy M-C, Meunier PJ, Delmas PD (1993) Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture in elderly women. J Clin Invest 91:1769-1774
33. Szulc P, Arlot M, Chapuy M-C, Duboeuf F, Meunier PJ, Delmas PD (1994) Serum undercarboxylated osteocalcin correlates with hip bone mineral density in elderly women. J Bone Miner Res 9:1591-1595
34. Elkeles A (1957) A comparative radiological study of calcified atheroma in males and females over 50 years of age. Lancet ii:714-715
35. Anderson JB, Barnett E, Nordin BEC (1964) The relation between osteoporosis and aortic calcification. Br J Radiol 37: 910-912
36. Frye MA, Melton LJ III, Bryant SC, Fitzpatrick LA, Wahner HW, Schwartz RS, Riggs BL (1992) Osteoporosis and calcification of the aorta. Bone Miner 19:185-194
37. Ouchi Y, Akishita M, de Souza AC, Nakamura T, Orimo H (1993) Age-related loss of bone mass and aortic/aortic valve calcification - reevaluation of recommended dietary allowance of calcium in the elderly. Ann NY Acad Sci 676:297-307
38. Browner WA, Pressman AR, Nevitt MC, Cauley JA, Cummings SR (1993) Association between low bone density and stroke in elderly women. Stroke 24:940-946
39. Compston JE, Silver AC, Croucher PI, Brown RC, Woodhead JS Elevated serum intact parathyroid hormone levels in elderly patients with hip fracture. Clin Endocrinol 31:667-672
40. Minisola S, Carnevale V, Pacitti MT, Romagnoli E, Scarnecchia L, Rosso R, Minisola G, Mazzuoli GF (1993) Serum osteocalcin in metabolic bone disease: What is its real significance? J Endocrinol Invest 16:277-279
41. Saupe J, Shearer MJ, Kohlmeier M (1993) Phylloquinone transport and its influence on γ-carboxyglutamate residues of osteocalcin in patients on maintenance hemodialysis. Am J Clin Nutr 58:204-208
42. Watson KE, Boström K, Ravindranath R, Lam T, Norton B, Demer LL (1994) TGF-β1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify. J Clin Invest 93: 2106-2113
43. Otawara Y, Price PA (1986) Developmental appearance of matrix Gla-protein during calcification in the rat. J Biol Chem 261:10828-1082
44. Pettifor JM, Benson R (1975) Congenital malformations associated with the administration of oral anticoagulants during pregnancy. J Pediatr 86:459-462
45. Price PA, Lothringer JW, Baukol SA, Reddi AH (1981) Developmental appearance of the vitamin K-dependent bone protein during calcification: analysis of mineralizing tissues in human, calf, and rat. J Biol Chem 256:3781-3784
46. Vermeer C, Knapen MHJ, Jie K-SG (1995) Role of vitamin K in bone metabolism. Annu Rev Nutr 15:1-22