CD44 protein levels and its biological activity are regulated in Balb/c 3T3 fibroblasts by serum factors and by transformation with the ras but not with the sis oncogene

Journal of Cellular Physiology

Volumn 169, Issue 2, 1996, Pages 341-349

  Kogerman, Priit ^a   Sy, Man Sun ^a   Culp, Lloyd A ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HERMES ANTIGEN; HYALURONIC ACID; PLATELET DERIVED GROWTH FACTOR;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CELL TRANSFORMATION; CHILD; FIBROBLAST; NONHUMAN; ONCOGENE; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SERUM FACTOR;

3T3 CELLS; ANIMALS; ANTIGENS, CD44; BLOOD PROTEINS; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL ADHESION; CULTURE MEDIA; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; HYALURONIC ACID; MICE; MICE, INBRED BALB C; NEOPLASM METASTASIS; NERVE TISSUE PROTEINS; ONCOGENES; TRANSFORMATION, GENETIC;

ANIMALIA;

EID: 0029860626     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199611)169:2<341::AID-JCP13>3.0.CO;2-C     Document Type: Article

References (38)

1. Bartolazzi, A., Peach, R., Aruffo, A., and Stamenkovic, I. (1994) Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development. J. Exp. Med., 180:53-66.
2. Baserga, R. (1994) Oncogenes and the strategy of growth factors. Cell, 79:927-930.
3. Culty, M., Miyake, K., and Underhill, C.B. (1992) The hyaluronan receptor (CD44) participates in the uptake and degradation of hyaluronan. J. Cell Biol., 116:1055-1062.
4. Culty, M., Shirazi, M., Thompson, E.W., and Underhill, C.B. (1994) Binding and degradation of hyaluronan by human breast cancer cell lines expressing different forms of CD44: Correlation with invasive potential. J. Cell. Physiol., 160:275-286.
5. Drozdoff, V., and Pledger, W.J. (1991) Cellular response to platelet-derived growth factor AB after downregulation of PDGF α-receptors. J. Biol. Chem., 266:17165-17172.
6. Fox, S.B., Fawcett, J.B., Jackson, D., Collins, I., Gatter, K.C., Harris, A.L., Gearing, A., and Simmons, D.L. (1994) Normal human tissues, in addition to some tumors, express multiple different CD44 isoforms. Cancer Res., 54:4539-4546.
7. Gunthert, U., Hofmann, M., Rudy, W., Reber, S., Zoller, M., Haußmann, I., Matzku, S., Wenzel, A., Ponta, H., and Herrlich, P. (1991) A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell, 65:13-24.
8. Guo, Y.J., Ma, J., Wang, J.H., Lin, S.C., Chang, H.C., Bigby, M., and Sy, M.S. (1993) Hyaluronic acid and anti-CD44 antibodies have distinct effects on the activation of murine T-cell hybridomas and normal T-lymphocytes. Cell. Immunol., 152:186-199.
9. Hofmann, M., Rudy, W., Zoller, M., Tolg, C., Ponta, H., Herrlich, H., and Gunthert, U. (1991) CD44 splice variants confer metastatic behavior in rats: Homologous sequences are expressed in human tumor cell lines. Cancer Res., 51:5292-5297.
10. Hofmann, M., Rudy, W., Gunthert, U., Zimmer, S.G., Zawadzki, V., Zoller, M., Lichtner, R.B., Herrlich, P., and Ponta, H. (1993) A link between ras and metastatic behavior of tumor cells: ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants in CREF cells. Cancer Res., 53:1516-1521.
11. Hunter, T. (1991) Cooperation between oncogenes. Cell, 64:249-270.
12. Jamal, H.H., Cano-Gauci, D.F., Buick, R.N., and Filmus, J. (1994) Activated ras and src induce CD44 overexpression in rat intestinal epithelial cells. Oncogene, 9:417-423.
13. Keating, M.T., and Williams, L.T. (1987) Processing of the platelet-derived growth factor receptor. J. Biol. Chem., 262:7932-7937.
14. Kogerman, P., Sy, M.-S., and Culp, L.A. (1996) Oncogene-dependent expression of CD44 in Balb/c 3T3 derivatives: Correlation with metastatic capacity. Clin. Exp. Metastasis, 14:73-82.
15. Laemmli, U. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227:680-685.
16. Lesley, J., Hyman, R., and Kincade, P.W. (1993) CD44 and its interaction with extracellular matrix. Adv. Immunol., 54:271-335.
17. Lin, W.-C., Pretlow, T.P., Pretlow, T.G., and Culp, L.A. (1990) Bacterial lacZ gene: A highly sensitive marker to detect micrometastasis formation during tumor progression. Cancer Res., 50:2808-2817.
18. Lin, W.-C., Pretlow, T.P., Pretlow, T.G., and Culp, L.A. (1992) High resolution analysis of two different classes of tumor cells in situ tagged with alternative marker genes. Am. J. Path., 141:1331-1342.
19. Lin, W.-C., O'Connor, K.L., and Culp, L.A. (1993) Complementation of two related tumor cell classes during experimental metastasis tagged with different histochemical marker genes. Br. J. Cancer, 67:910-921.
20. Matsumura, Y., and Tarin, D. (1992) Significance of CD44 gene products for cancer diagnosis and disease evaluation. Lancet, 340:1053-1058.
21. Miura, M., Li, S.-W., Dumenil, G., and Baserga, R. (1994) Platelet-derived growth factor-induced expression of messenger RNA for the proliferating cell nuclear antigen requires a functional receptor for the insulin-like growth factor 1. Cancer Res., 54:2472-2477.
22. Miyake, K., Underhill, C.B., Lesley, J., and Kincade, P.W. (1990a) Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition. J. Exp. Med., 172:69-75.
23. Miyake, K., Medina, K.L., Hayashi, S.I., Ono, S., Hamaoka, T., and Kincade, P.W. (1990b) Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures. J. Exp. Med., 171:477-488.
24. O'Connor, K., and Culp, L.A. (1994) Topological and quantitative analyses of early events in tumor formation using histochemically tagged transformed 3T3 cells. Oncol. Rep., 1:869-876.
25. Pardee, A.B. (1989) G1 events and regulation of cell proliferation. Science, 246:603-608.
26. Radinsky, R., and Culp, L.A. (1991) Clonal dominance of select subsets of viral Kirsten-ras transformed 3T3 cells during tumor progression. Intl. J. Cancer, 48:148-159.
27. Radinsky, R., Kraemer, P.M., Raines, M.A., Kung, H.J., and Culp, L.A. (1987) Amplification and rearrangement of the Kirsten-ras oncogene in virus-transformed Balb/c 3T3 cells during malignant tumor progression. Proc. Natl. Acad. Sci. USA, 84:5143-5147.
28. Radinsky, R., Kraemer, P.M., Proffitt, M.R., and Culp, L.A. (1988) Clonal diversity of the Kirsten-ras oncogene during tumor progression: Mechanisms of amplification and rearrangement. Cancer Res., 48:4941-4953.
29. Rudy, W., Hofmann, M., Schwartz-Albiez, R., Zoller, M., Heider, K.H., Ponta, H., and Herrlich, P. (1993) Two major CD44 proteins expressed on a metastatic rat tumor cell line: each one individually suffices to confer metastatic behavior. Cancer Res., 53:1262-1268.
30. Seppa, H., Grotendorst, G., Seppa, S., Schiffmann, E., and Martin, G.R. (1982) Platelet-derived growth factor is chemotactic for fibroblasts. J. Cell. Biol., 92:584-588.
31. Sy, M.S., Guo, Y.J., and Stamenkovic, I. (1991) Distinct effects of two CD44 isoforms on tumor growth in vivo. J. Exp. Med., 174:859-866.
32. Ullrich, A., and Schlessenger, J. (1990) Signal transduction by receptors with tyrosine kinase activity. Cell, 61:203-212.
33. Underhill, C.B. (1992) CD44: The hyaluronan receptor. J. Cell Sci., 103:293-298.
34. Vaziri, C., and Faller, D.V. (1995) Repression of platelet-derived growth factor β-receptor expression by mitogenic growth factors and transforming oncogenes in murine 3T3 fibroblasts. Mol. Cell. Biol., 15:1244-1253.
35. Wheatley, S.C., Isacke, S.M., and Crossley, P.H. (1993) Restricted expression of the hyaluronan receptor, CD44, during postimplantation mouse embryogenesis suggests key roles in tissue formation and patterning. Development, 119:295-306.
36. Wielenga, V.J.M., Heider, K.-H., Offerhaus, G.J.A., Adolf, G.R., van den Berg, F.M., Ponta, H., Herrlich, P., and Pals, S.T. (1993) Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression. Cancer Res., 53:4754-4756.
37. Yu, C., Prochownik, E.V., Imperiale, M.J., and Jove, R. (1993) Attenuation of serum inducibility of immediate-early genes by oncoproteins in tyrosine kinase signaling pathways. Mol. Cell. Biol., 13:2011-2019.
38. Zheng, Z., Katoh, S., He, Q., Oritani, K., Miyake, K., Lesley, J., Hyman, R., Hamik, A., Parkhouse, R.M.E., Farr, A.G., and Kincade, P.W. (1995) Monoclonal antibodies to CD44 and their influence on hyaluronan recognition. J. Cell Biol., 130:485-495.