Interleukin-4, transforming growth factor β1, and dexamethasone inhibit superantigen-induced prostaglandin E2-dependent collagenase gene expression through their action on cyclooxygenase-2 and cytosolic phospholipase A2

Laboratory Investigation

Volumn 75, Issue 4, 1996, Pages 529-538

  Mehindate, Khalil ^a   Al Daccak, Reem ^a   Aoudjit, Fawzi ^a   Damdoumi, Farida ^a   Fortier, Michel ^a   Borgeat, Pierre ^a   Mourad, Walid ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; DEXAMETHASONE; INTERLEUKIN 4; PHOSPHOLIPASE A2; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; TRANSFORMING GROWTH FACTOR BETA1;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; ENZYME ACTIVITY; ENZYME REGULATION; EXTRACELLULAR MATRIX; GENE CONTROL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; REGULATORY MECHANISM; RHEUMATOID ARTHRITIS; SYNOVIOCYTE;

ARTHRITIS, RHEUMATOID; COLLAGENASES; CYCLOOXYGENASE 2; CYTOSOL; DEXAMETHASONE; DINOPROSTONE; DOWN-REGULATION; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTERLEUKIN-4; ISOENZYMES; MEMBRANE PROTEINS; PHOSPHOLIPASES A; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SUPERANTIGENS; SYNOVIAL MEMBRANE; TRANSFORMING GROWTH FACTOR BETA;

EID: 0029859353     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. 2 expressed in insect cells is extensively phosphorylated on Ser-505. Biochim Biophys Acta 1244:157-164.
2. Al-Daccak R, Mehindate K, Poubelle PE, and Mourad W (1994). Signalling via MHC class II molecules selectively induces IL-1β over IL-1 receptor antagonist gene expression. Biochem Biophys Res Commun 201:855-860.
3. Alexander CM and Werb Z (1991). Extracellular matrix degradation. In: Hay ED, editor. Cell biology of extracellular matrix. New York: Plenum Press, 255-302.
4. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS, Medsger TA Jr, Mitchell DM, Neustadt DH, Pinall RS, Shaller JG, Sharp JT, Wilder RL, and Hunder GG (1988). The American Rheumatism Association 1987. Revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315-324.
5. Birkedal-Hansen H, Werb Z, Welgus H, and Van Wart H (1992). Matrix metalloproteinases and their inhibitors. New York: Gustav Fischer Verlag.
6. Brandes ME, Allen JB, Ogawa Y, and Wahl S (1991). Transforming growth factor β1 suppresses acute and chronic arthritis in experimental animals. J Clin Invest 87:1108-1113.
7. Brinckerhoff CE (1991). Joint destruction in arthritis: Metalloproteinases in the spotlight. Arthritis Rheum 34:1073-1075.
8. Brinckerhoff CE and Auble DT (1990). Regulation of collagenase gene expression in synovial fibroblasts. Ann N Y Acad Sci 580:355-374.
9. Brinckerhoff CE, Ruby PL, Austin SD, Fini ME, and White HD (1987). Molecular cloning of human synovial cell collagenase and selection of a single gene from genomic DNA. J Clin Invest 79:542-546.
10. Clark M, Powell LK, Ramsey S, Hazleman BL, and Cawston TE (1993). The measurement of collagenase, tissue inhibitor of metalloproteinases (TIMP), and collagenase-TIMP complex in synovial fluids from patients with osteoarthritis and rheumatoid arthritis. Arthritis Rheum 36:372-379.
11. Corcorant ML, Stetler-Stevenson W, Brown PD, and Wahl LM (1991). Interleukin 4 inhibition of prostaglandin E2 synthesis blocks interstitial and 92-KDa type collagenase/ gelatinase production of human monocytes. J Biol Chem 267:515-519.
12. D'Andrea A, Ma X, Aste-Amezaga M, Paganin C, and Trinchieri G (1995). Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: Priming for IL-12 and tumor necrosis factor α production. J Exp Med 181:537-346.
13. Dayer JM, Krane SM, Russell GG, and Robinson DG (1976). Production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells. Proc Natl Acad Sci USA 73:945-949.
14. Fini ME and Girard MT (1990). The pattern of metalloproteinase expression by corneal fibroblasts is altered by passage in cell culture. J Cell Sci 97:373-383.
15. Flower RJ and Blackwell GJ (1976). The importance of phospholipase A2 in prostaglandin biosynthesis. Biochem Pharmacol 25:285-291.
16. Gravallese EM, Darling JM, Ladd AL, Katz JN, and Glimcher LH (1991). In situ hybridization studies of stromelysin and collagenase messenger RNA expression in rheumatoid and osteoarthritis synovium. Arthritis Rheum 34:1076-1084.
17. Gùnther M, Haubeck HD, Van De Leur E, Blaser J, Bender S, Gùtgemann I, Fisher DC, Tschesche H, Greiling H, Heinrich C, and Graeve L (1994). Transforming growth factor β1 regulates tissue inhibitor of metalloproteinase-1 expression in differentiated human articular chondrocytes. Arthritis Rheum 37:395-405.
18. Habib A, Créminon C, Frobert Y, Grassi J, Pradelles P, and Maclouf J (1993). Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2. J Biol Chem 268:23448-23454.
19. 2. Proc Natl Acad Sci U S A 86:3803-3807.
20. Hemler ME, Lands WEM, and Smith WL (1976). Purification of the cyclooxygenase that forms prostaglandins: Demonstration of two forms of iron in the holoenzyme. J Biol Chem 251:5575-5579.
21. Jonat C, Rahmsdorf HJ, Park KK, Cato ACB, Gebel S, Pota H, and Herrlich P (1990). Antitumor promotion and antiinflammation down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell 62:1189-1204.
22. Kerr LD, Miller DB, and Matrisian LM (1990). TGF-β1 inhibition of transin/stromelysin gene expression is mediated through a Fos binding sequence. Cell 61:267-278.
23. Khokha R, Waterhouse P, Yagel S, Lala PK, Overall CM, Norton G, and Denhardt DT (1989). Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells. Science 243:947-950.
24. 2α, production by oxytocin and platelet-activating factor in bovine endothelial cells. J Reprod Fertil 103:239-247.
25. Krump E, Pouliot M, Naccache PH, and Borgeat P (1995). Leukotriene synthesis in calcium-depleted human neutrophils: Arachidonic acid release correlates with calcium influx. Biochem J 310:681-688.
26. Kujubu DA and Herschman HR (1992). Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene. J Biol Chem 267:7991-7994.
27. Lew W, Oppenheim JJ, and Matsushima K (1988). Analysis of the suppression of IL-1α and IL-1β production in human peripheral blood mononuclear adherent cells by a glucocorticoid hormone. J Immunol 140:1895-1902.
28. Mauviel A, Chen YQ, Dong W, Evans CH, and Uitto J (1993). Transcriptional interactions of transforming growth-factor-β with pro-inflammatory cytokines. Curr Biol 3:822-831.
29. McCachren SS (1991). Expression of metalloproteinases and metalloproteinase inhibitor in human arthritic synovium. Arthritis Rheum 34:1085-1093.
30. McCachren SS, Greer PK, and Niedel JE (1989). Regulation of human synovial fibroblast collagenase messenger RNA by interleukin-1. Arthritis Rheum 32:1539-1545.
31. McCartney-Francis N and Wahl SM (1994). A matter of life and death. J Leukoc Biol 55:401-409.
32. 2. J Immunol 155:3570-3577.
33. Mehindate K, Al-Daccak R, Rink L, Mecheri S, Hebert J, and Mourad W (1994a). Modulation of mycoplasma arthritides-derived superantigen-induced cytokine gene expression by dexamethasone and interleukin-4. Infect Immun 62:4716-4721.
34. Mehindate K, Al-Daccak R, Schall TJ, Mourad W (1994b). Induction of chemokine gene expression by major histocompatibility complex class II ligands in human fibroblast-like synoviocytes. J Biol Chem 269:32063-32069.
35. Mourad W, Mehindate K, Schall TJ, and McColl SH (1992). Engagement of major histocompatibility complex class II molecules by superantigen induces inflammatory cytokine gene expression in human rheumatoid fibroblast-like synoviocytes. J Exp Med 175:613-616.
36. Mukaida N, Zachariae CCO, Gusella GL, and Matsushima K (1991). Dexamethasone inhibits the induction of monocyte chemotactic activating factor production by IL-1 or tumor necrosis factor. J Immunol 146:1212-1215.
37. Niiro H, Otsuka T, Tanabe T, Hara S, Kuga S, Nemoto Y, Tanaka Y, Nakashima H, Kitajima S, Abe M, and Niho Y (1995). Inhibition by interleukin-10 of inducible cyclooxygenase expression in lipopolysaccharide-stimulated monocytes: Its underlying mechanism in comparison with interleukin-4. Blood 85:3736-3745.
38. Origuchi T, Eguchi K, Kawabe Y, Mizokami A, Ida H, and Nagataki S (1995). Synovial cells are potent antigen-presenting cells for superantigen staphylococcal enterotoxin B (SEB). Clin Exp Immunol 99:345-351.
39. Paliard X, West SJ, Lafferty JA, Clements JR, Kappler JW, Marrack P, and Kotzin B (1991). Evidence for the effects of a superantigen in rheumatoid arthritis. Science 253:325-329.
40. Pitzalis C, Kingsly G, Haskard D, and Panayi G (1988). The preferential accumulation of helper-induced T lymphocytes in inflammatory lesions: Evidence for regulation by selective endothelial and homotypic adhesion. Eur J Immunol 18: 1397-1404.
41. Posnett DN (1993). Do superantigens play a role in autoimmunity? Semin Immunol 5:65-72.
42. Ruscetti FW and Palladino MA (1991). Transforming growth factor-β and the immune system. Prog Growth Factor Res 3:159-175.
43. Scholl PR, Diez A, Mourad W, Parsonnet J, Geha RS, and Chatila T (1989). Toxic shock syndrome toxin 1 binds to major histocompatibility complex class II molecules. Proc Natl Acad Sci U S A 86:4210-4214.
44. Searles RP, Savage SM, Brozek CM, Marnell LL, and Hoffman CL (1988). Network regulation in rheumatoid arthritis. Arthritis Rheum 31:834-843.
45. Seitz M, Loetscher P, Dewald B, Towbin H, Ceska M, and Baggiolini M (1994). Production of interleukin-1 receptor antagonist, inflammatory chemotactic proteins, and prostaglandin E by rheumatoid and osteoarthritic synoviocytes-regulation by IFN-γ and IL-4. J Immunol 152:2060-2065.
46. Stricklin GP and Welgus HG (1983). Human skin fibroblast inhibitor: Purification and biochemical characterization. J Biol Chem 258:12252-12258.
47. Tobler A, Meier R, Seitz M, Dewald B, Baggiolini M, and Fey MF (1992). Glucocorticoids downregulate gene expression of GM-CSF, NAP/IL-8 and IL-6 but not of M-CSF in human fibroblasts. Blood 79:45-51.
48. 2 expressed in Trichoplusia ni larvae. Isolation and kinetic properties of the enzyme. Protein Expr Purif 4:490-498.
49. Tumang JR, Posnett DN, Cole BC, Crow MK, and Friedman SM (1990). Helper T cell-dependent human B cell differentiation mediated by mycoplasma superantigen bridge. J Exp Med 171:2153-2158.
50. Wahl SM (1992). TGF-β in inflammation. A cause and a cure. J Clin Immunol 12:61-74.
51. Wallner BP, Mattaliano RJ, Hession C, Cate RL, Tizard R, Sinclair LK, Foeller C, Chow EP, Browning JL, Ramachandran KL, and Pepinsky RB (1986). Cloning and expression of human lipocortin, a phospholipase A2 inhibitor with potential anti-inflammatory activity. Nature 320:77-81.
52. Woessner JF (1991). Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J 5:2145-2154.
53. Wong HL, Costa GL, Lotze MT, and Wahl SM (1993). Interleukin (IL) 4 differentially regulates IL-1 family gene expression and synthesis in vitro and in vivo. J Exp Med 177:775-781.
54. Wong HL, Lotze MT, Wahl LM, and Wahl SM (1992). Administration of recombinant IL-4 to human regulates gene expression, phenotype and function of circulating monocytes. J Immunol 148:2118-2125.