Skin absorption of solvent mixtures - Effect of vehicles on skin absorption of toluene

Industrial Health

Volumn 34, Issue 4, 1996, Pages 369-378

  Tsuruta, Hiroshi ^a  

^a NATL INSTITUTE OF INDUSTRIAL HEALTH   (Japan)

Author keywords

Benzene; Methanol; Mouse; Penetration enhancer; Skin absorption; Solvent mixtures; Toluene

Indexed keywords

BENZENE; THINNER; TOLUENE;

ANIMAL EXPERIMENT; ARTICLE; MALE; MOUSE; NONHUMAN; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; OCCUPATIONAL HEALTH; SKIN ABSORPTION;

ANIMALIA;

EID: 0029859001     PISSN: 00198366     EISSN: None     Source Type: Journal    
DOI: 10.2486/indhealth.34.369     Document Type: Article

References (24)

1. Inoue T, Takeuchi Y, Hisanaga N, Ono Y, Iwata M, Ogata M, Saito K, Sakurai H, Hara I, Matsusita T, Ikeda M. A nationwide survey on organic solvents components in various solvent products: Part 1. Homogeneous products such as thinners, degreasers and reagents. Ind Health 1983; 21: 175-83.
2. Dutkiewicz T, Tyras H. Skin absorption of toluene, styrene, and xylene by man. Br J Ind Med 1968; 25: 243.
3. Sato A, Nakajima, T. Differences following skin or inhalation exposure in the absorption and excretion kinetics of trichloroethylene and toluene. Br J Ind Med 1978; 35: 43-9.
4. Aitio A, Pekari K, Jarvisalo J. Skin absorption as a source of error in biological monitoring. Scand J Work Environ Health 1984; 10: 317-20.
5. Daniell W, Stebbins A, Kaiman d, O'Donnell JF, Horstman SW. The contributions to solvent uptake by skin and inhalation exposure. Am Ind Hyg Assoc J 1992; 53: 124-9.
6. Ursin C, Hansen CM, Van Dyk JW, Jensen PO, Christensen IbJ, Ebbehoej J. Permeability of commercial solvents through living human skin. Am Ind Hyg Assoc J 1995; 56: 651-60.
7. Tsuruta H. Percutaneous absorption of organic solvents III On the penetration rates of hydrophobic solvents through the excised rat skin. Ind. Health 1982; 20, 335-45.
8. Jakobson I, Wahlberg JE, Holmberg B, Johansson G. Uptake via the blood and elimination of 10 organic solvents following epicutaneous exposure of anesthetized guinea pigs. Toxicol Appl Pharm 1982; 63: 181-7.
9. Boman A, Wahlberg JE. Percutaneous absorption of 3 organic solvents in the guinea pig. Contact Dermatitis 1989; 21: 36-45.
10. Susten AS, Niemeier RW, Simon SD. In vivo percutaneous absorption studies of volatile organic solvents in hairless mice. II. Toluene, ethylbenzene, and aniline. J Appl Toxicol 1990; 10: 217-25.
11. Morgan DL, Cooper SW, Carlock DL, Sykora JJ, Sutton B, Mattie DR, McDougal JN. Dermal absorption of neat and aqueous volatile organic chemicals in the fischer 344 rat. Environ Res 1991; 55: 51-63.
12. Riihimaki M, Pfaffli P. Percutaneous absorption of solvent vapors in man. Scand J Work Environ Health 1978; 4: 73-85.
13. Tsuruta H, Iwasaki K, Kanno S. A method for calculating the skin absorption rate from the amount retained in the whole body of skin-absorbed toluene in mice. Ind Health 1987; 25 : 215-20.
14. Tsuruta H. Skin absorption of organic solvent vapors in nude mice in vivo. Ind Health 1989; 27: 37-47.
15. McDougal JN, Jepson GW, Clewell III HJ, Gargas ML, Andersen ME. Dermal absorption of organic chemical vapors in rats and humans. Fundamental Appl Toxicol 1990; 14: 299-308.
16. Divincenzo GD, Hamilton ML, Kaplan CJ, Krasavage WJ, Donoghue JL. Studies on the respiratory uptake and excretion and skin absorption of methyl n-butyl ketone in humans and dogs. Toxicol Appl Pharmarcol 1978; 44: 593-604.
17. Riihimaki V. Percutaneous absorption of m-xylene from a mixture of m-xylene and isobutyl alcohol in man. Scand J Work Environ Health 1979; 5: 143-50.
18. Ishihara N, Ikeda M. Effect of solvents and solutes on the percutaneous absorption of ni-dinitrobenzene. Int Arch Occup Environ Health 1979; 44: 91-8.
19. Skowronski GA, Turkall RM, Abdel-Rahman MS. Effects of soil on percutaneous absorption of toluene in male rats. J Toxico Enviro Health 1989; 26: 373-84.
20. Tsuruta H, Iwasaki K. A procedure for determining volatile solvents in mouse whole body. Ind Health 1984; 22: 219-22.
21. Rowland M, Tozer TN. Clinical Pharmakinetics: Concepts and Applications, Lea&Febiger, Philadelphia, 1989; 14-5, 33-6.
22. Dugard PH. Skin permeability theory in relation to measurements of percutaneous absorption in toxicology. In Marzulli FN, Maibach HI. eds. Dermatotoxicology and pharmacology. Hemisphere Publishing Corporation, Washington, 1977; 525-50.
23. Berode M, Droz PO, Guillemin M. Human exposure to styrene. VI. Percutaneous absorption in human volunteers. Int Arch Occup Environ Health 1985; 55: 331-6.
24. Cooper E. Vehicle effects on skin penetration. In: Bronaugh RL, Maibach HI eds. Percutaneous absorption. Marcel Dekker, New York: 1985; 525-9.