-
1
-
-
10244237141
-
The effect of ranitidine on morphine metabolism in isolated hepatocytes from rat and guinea pig
-
Aasmundstad, T. A., B. Q. Xu & J. Mørland: The effect of ranitidine on morphine metabolism in isolated hepatocytes from rat and guinea pig. J. Basic Clin. Physiol. Pharmacol. 1992, 3 (Suppl.), 227.
-
(1992)
J. Basic Clin. Physiol. Pharmacol.
, vol.3
, Issue.SUPPL.
, pp. 227
-
-
Aasmundstad, T.A.1
Xu, B.Q.2
Mørland, J.3
-
2
-
-
0027250487
-
Different biotransformation of morphine in isolated liver cells from guinea pig and rat
-
Aasmundstad, T. A., Å. Ripel, E. Bodd, A. Bjorneboe & J. Mørland: Different biotransformation of morphine in isolated liver cells from guinea pig and rat. Biochem. Pharmacol. 1993, 46, 961-968.
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 961-968
-
-
Aasmundstad, T.A.1
Ripel, Å.2
Bodd, E.3
Bjorneboe, A.4
Mørland, J.5
-
3
-
-
0028825450
-
Distribution of morphine-6-glucuronide and morphine across the blood-brain-barrier in awake, freely moving rats investigated by in vivo microdialysis sampling
-
Aasmundstad, T. A., J. Morland & R. Paulsen: Distribution of morphine-6-glucuronide and morphine across the blood-brain-barrier in awake, freely moving rats investigated by in vivo microdialysis sampling. J. Pharmacol. Exp. Therap. 1995, 275, 435 441.
-
(1995)
J. Pharmacol. Exp. Therap.
, vol.275
, pp. 435441
-
-
Aasmundstad, T.A.1
Morland, J.2
Paulsen, R.3
-
4
-
-
0026032347
-
Morphine-6-glucuronide contributes to rewarding effects of opiates
-
Abbott, F. V. & K. B. Franklin: Morphine-6-glucuronide contributes to rewarding effects of opiates. Life Sci. 1991, 48, 1157-1163.
-
(1991)
Life Sci.
, vol.48
, pp. 1157-1163
-
-
Abbott, F.V.1
Franklin, K.B.2
-
5
-
-
0023701349
-
Morphine-6-glucuronide: Analgesic effects and receptor binding profile in rats
-
Abbott, F. V. & R. M. Palmour. Morphine-6-glucuronide: analgesic effects and receptor binding profile in rats. Life Sci. 1988, 43, 1685-1695.
-
(1988)
Life Sci.
, vol.43
, pp. 1685-1695
-
-
Abbott, F.V.1
Palmour, R.M.2
-
6
-
-
0027937561
-
Morphine and morphine metabolite kinetics in the rat brain as assessed by transcortical microdialysis
-
Barjavel, M., P. Sandouk, M. Plotkine & J. M. Scherrmann: Morphine and morphine metabolite kinetics in the rat brain as assessed by transcortical microdialysis. Life Sci. 1994, 55, 1301-1308.
-
(1994)
Life Sci.
, vol.55
, pp. 1301-1308
-
-
Barjavel, M.1
Sandouk, P.2
Plotkine, M.3
Scherrmann, J.M.4
-
7
-
-
0028226888
-
The excitatory effects of morphine-3-glucuronide are attenuated by LY274614, a competitive NMDA receptor antagonist, and by midazolam, an agonist at the benzodiazepine site on the GABAA receptor complex
-
Bartlett, S. E., T. Cramond & M. T. Smith: The excitatory effects of morphine-3-glucuronide are attenuated by LY274614, a competitive NMDA receptor antagonist, and by midazolam, an agonist at the benzodiazepine site on the GABAA receptor complex. Life Sci. 1994a, 54, 687-694.
-
(1994)
Life Sci.
, vol.54
, pp. 687-694
-
-
Bartlett, S.E.1
Cramond, T.2
Smith, M.T.3
-
8
-
-
0028017873
-
Pharmacology of morphine and morphine-3-glucuronide at opiod, excitatory amino acid, GABA and glycine binding sites
-
Bartlett, S. E., P. R. Dodd & M. T. Smith: Pharmacology of morphine and morphine-3-glucuronide at opiod, excitatory amino acid, GABA and glycine binding sites. Pharmacology & Toxicology 1994b. 75, 73-81.
-
(1994)
Pharmacology & Toxicology
, vol.75
, pp. 73-81
-
-
Bartlett, S.E.1
Dodd, P.R.2
Smith, M.T.3
-
9
-
-
0014645531
-
High-yield preparation of isolated rat liver parenchymal cells
-
Berry, M. N. & D. S. Friend: High-yield preparation of isolated rat liver parenchymal cells. J. Cell Biol. 1969, 43, 506-520.
-
(1969)
J. Cell Biol.
, vol.43
, pp. 506-520
-
-
Berry, M.N.1
Friend, D.S.2
-
10
-
-
0022650484
-
Ethanol inhibition of codeine and morphine metabolism in isolated rat hepatocytes
-
Bodd, E., C. A. Drevon, N. Kveseth, H. Olsen & J. Morland: Ethanol inhibition of codeine and morphine metabolism in isolated rat hepatocytes. J. Pharmacol. Exp. Therap. 1986a. 237, 260-264.
-
(1986)
J. Pharmacol. Exp. Therap.
, vol.237
, pp. 260-264
-
-
Bodd, E.1
Drevon, C.A.2
Kveseth, N.3
Olsen, H.4
Morland, J.5
-
11
-
-
0022860525
-
Mechanisms behind the inhibitory effect of ethanol on the conjugation of morphine in rat hepatocytes
-
Bodd, E., G. Gadeholt, P I. Christensson & J. Morland: Mechanisms behind the inhibitory effect of ethanol on the conjugation of morphine in rat hepatocytes. J. Pharmacol. Exp. Therap. 1986b, 239, 887-890.
-
(1986)
J. Pharmacol. Exp. Therap.
, vol.239
, pp. 887-890
-
-
Bodd, E.1
Gadeholt, G.2
Christensson, P.I.3
Morland, J.4
-
12
-
-
0021064062
-
Tolerance and cross-tolerance to morphine and ethanol in mice selectively bred for differential sensitivity to ethanol
-
Brick, J. & G. P. Horowitz: Tolerance and cross-tolerance to morphine and ethanol in mice selectively bred for differential sensitivity to ethanol. J. Stud. Alcohol. 1983, 44, 770-779.
-
(1983)
J. Stud. Alcohol.
, vol.44
, pp. 770-779
-
-
Brick, J.1
Horowitz, G.P.2
-
13
-
-
0025830147
-
Mu receptor binding of some commonly used opioids and their metabolites
-
Chen, Z. R., R. J. Irvine, A. A. Somogyi & F. Bochner: Mu receptor binding of some commonly used opioids and their metabolites. Life Sci. 1991, 48, 2165-2171.
-
(1991)
Life Sci.
, vol.48
, pp. 2165-2171
-
-
Chen, Z.R.1
Irvine, R.J.2
Somogyi, A.A.3
Bochner, F.4
-
14
-
-
0026013189
-
Morphine-6-glucuronide: Receptor binding profile in bovine caudate nucleus
-
Christensen, C. B. & L. Reiff: Morphine-6-glucuronide: Receptor binding profile in bovine caudate nucleus. Pharmacology & Toxicology 1991, 68, 151-153.
-
(1991)
Pharmacology & Toxicology
, vol.68
, pp. 151-153
-
-
Christensen, C.B.1
Reiff, L.2
-
15
-
-
0027506866
-
Pharmacokinetics and pharmacodynamics of morphine-3-glucuronide in rats and its influence on the antinociceptive effect of morphine
-
Ekblom, M., M. Gårdmark & M. Hammarlund-Udenaes: Pharmacokinetics and pharmacodynamics of morphine-3-glucuronide in rats and its influence on the antinociceptive effect of morphine. Biopharm. Drug Disp. 1993, 14, 1-11.
-
(1993)
Biopharm. Drug Disp.
, vol.14
, pp. 1-11
-
-
Ekblom, M.1
Gårdmark, M.2
Hammarlund-Udenaes, M.3
-
16
-
-
0026724017
-
Further evidence that morphine-6 beta-glucuronide is a more potent opioid agonist than morphine
-
Frances, B., R. Gout, B. Monsarrat, J. Cros & J. M. Zajac: Further evidence that morphine-6 beta-glucuronide is a more potent opioid agonist than morphine. J. Pharmacol. Exp. Therap. 1992, 262, 25-31.
-
(1992)
J. Pharmacol. Exp. Therap.
, vol.262
, pp. 25-31
-
-
Frances, B.1
Gout, R.2
Monsarrat, B.3
Cros, J.4
Zajac, J.M.5
-
17
-
-
0026059585
-
Antinociceptive and ventilatory effects of the morphine metabolites: Morphine-6-glucuronide and morphine-3-glucuronide
-
Gong, Q. L., T. Hedner, J. Hedner, R. Bjorkman & G. Nordberg: Antinociceptive and ventilatory effects of the morphine metabolites: morphine-6-glucuronide and morphine-3-glucuronide. Eur. J. Pharmacol. 1991, 193, 47-56.
-
(1991)
Eur. J. Pharmacol.
, vol.193
, pp. 47-56
-
-
Gong, Q.L.1
Hedner, T.2
Hedner, J.3
Bjorkman, R.4
Nordberg, G.5
-
18
-
-
0026501373
-
Morphine-3-glucuronide may functionally antagonize morphine-6-glucuronide induced antinociception and ventilatory depression in the rat
-
Gong, Q. L., J. Hedner, R. Bjorkman & T. Hedner: Morphine-3-glucuronide may functionally antagonize morphine-6-glucuronide induced antinociception and ventilatory depression in the rat. Pain 1992, 48, 249-255.
-
(1992)
Pain
, vol.48
, pp. 249-255
-
-
Gong, Q.L.1
Hedner, J.2
Bjorkman, R.3
Hedner, T.4
-
19
-
-
0025219273
-
Analgesic efficacy and CSF pharmacokinetics of intrathecal morphine-6-glucuronide: Comparison with morphine
-
Hanna, M. H., S. J. Peat, M. Woodham, A. Knibb & C. Fung: Analgesic efficacy and CSF pharmacokinetics of intrathecal morphine-6-glucuronide: comparison with morphine. Br. J. Anaesth. 1990, 64, 547-550.
-
(1990)
Br. J. Anaesth.
, vol.64
, pp. 547-550
-
-
Hanna, M.H.1
Peat, S.J.2
Woodham, M.3
Knibb, A.4
Fung, C.5
-
20
-
-
0027212338
-
Lack of effect of morphine-3-glucuronide on the spinal antinociceptive actions of morphine in the rat: An electrophysiological study
-
Hewett, K., A. H. Dickenson & H. J. McQuay: Lack of effect of morphine-3-glucuronide on the spinal antinociceptive actions of morphine in the rat: an electrophysiological study. Pain 1993, 53, 59-63.
-
(1993)
Pain
, vol.53
, pp. 59-63
-
-
Hewett, K.1
Dickenson, A.H.2
McQuay, H.J.3
-
21
-
-
0025106883
-
Longitudinal patterns of alcohol use by narcotics addicts
-
Ed.: M. Galanter. Plenum Press, New York
-
Hser, Y. I., M. D. Anglin & K. Powers: Longitudinal patterns of alcohol use by narcotics addicts. In: Recent developments in alcoholism. Vol. 8. Combined alcohol and other drug dependence. Ed.: M. Galanter. Plenum Press, New York, 1990, pp. 145-171.
-
(1990)
Recent Developments in Alcoholism. Vol. 8. Combined Alcohol and Other Drug Dependence
, vol.8
, pp. 145-171
-
-
Hser, Y.I.1
Anglin, M.D.2
Powers, K.3
-
22
-
-
0001676359
-
Interactions of ethyl alcohol and other drugs
-
Eds.: B. Kissin & H. Begleiter. Plenum Press, New York
-
Kissin, B.: Interactions of ethyl alcohol and other drugs. In: The biology of alcoholism, Vol. 3. Clinical pathology. Eds.: B. Kissin & H. Begleiter. Plenum Press, New York, 1974, pp. 109-161.
-
(1974)
The Biology of Alcoholism, Vol. 3. Clinical Pathology
, vol.3
, pp. 109-161
-
-
Kissin, B.1
-
23
-
-
0025202080
-
A new metabolic pathway of morphine: In vivo and in vitro formation of morphinone and morphine-glutathione adduct in guinea pig
-
Kumagai, Y., T. Todaka & S. Toki: A new metabolic pathway of morphine: in vivo and in vitro formation of morphinone and morphine-glutathione adduct in guinea pig. J. Pharmacol. Exp. Therap. 1990, 255, 504-510.
-
(1990)
J. Pharmacol. Exp. Therap.
, vol.255
, pp. 504-510
-
-
Kumagai, Y.1
Todaka, T.2
Toki, S.3
-
24
-
-
0026693403
-
Differential inhibition of hepatic morphine UDP-glucuronosyltransferases by metal ions
-
Lawrence, A. J., A. Michalkiewicz, J. S. Morley, K. MacKinnon & D. Billington: Differential inhibition of hepatic morphine UDP-glucuronosyltransferases by metal ions. Biochem. Pharmacol. 1992, 43, 2335-2340.
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 2335-2340
-
-
Lawrence, A.J.1
Michalkiewicz, A.2
Morley, J.S.3
MacKinnon, K.4
Billington, D.5
-
25
-
-
0028111043
-
Morphine-6-glucuronide: A potent stimulator of locomotor activity in mice
-
Mørland, J., B. L. Jones, M. L. Palomares & R. L. Alkana: Morphine-6-glucuronide: a potent stimulator of locomotor activity in mice. Life Sci. 1994, 55, PL163-PL168.
-
(1994)
Life Sci.
, vol.55
-
-
Mørland, J.1
Jones, B.L.2
Palomares, M.L.3
Alkana, R.L.4
-
26
-
-
0023010970
-
Morphine metabolism in isolated rat hepatocytes and its implications for hepatotoxicity
-
Nagamatsu, K., Y. Ohno, H. Ikebuchi, A. Takahashi, T. Terao & A. Takanaka: Morphine metabolism in isolated rat hepatocytes and its implications for hepatotoxicity. Biochem. Pharmaco.l 1986, 35, 3543-3548.
-
(1986)
Biochem. Pharmacol .
, vol.35
, pp. 3543-3548
-
-
Nagamatsu, K.1
Ohno, Y.2
Ikebuchi, H.3
Takahashi, A.4
Terao, T.5
Takanaka, A.6
-
27
-
-
0026669218
-
The analgesic activity of morphine-6-glucuronide
-
Osborne, R., P. Thompson, S. Joel, D. Trew, N. Patel & M. Slevin: The analgesic activity of morphine-6-glucuronide. Brit. J. Clin. Pharmacol. 1992, 34, 130-138.
-
(1992)
Brit. J. Clin. Pharmacol.
, vol.34
, pp. 130-138
-
-
Osborne, R.1
Thompson, P.2
Joel, S.3
Trew, D.4
Patel, N.5
Slevin, M.6
-
28
-
-
0023620266
-
Morphine-6-glucuronide, a potent mu agonist
-
Pasternak, G. W., R. J. Bodnar, J. A. Clark & C. E. Inturrisi: Morphine-6-glucuronide, a potent mu agonist. Life Sci. 1987, 41, 2845-2849.
-
(1987)
Life Sci.
, vol.41
, pp. 2845-2849
-
-
Pasternak, G.W.1
Bodnar, R.J.2
Clark, J.A.3
Inturrisi, C.E.4
-
29
-
-
0024369341
-
Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite
-
Paul, D., K. M. Standifer, C. E. Inturrisi & G. W. Pasternak: Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite. J. Pharmacol. Exp. Therap. 1989, 251, 477-483.
-
(1989)
J. Pharmacol. Exp. Therap.
, vol.251
, pp. 477-483
-
-
Paul, D.1
Standifer, K.M.2
Inturrisi, C.E.3
Pasternak, G.W.4
-
30
-
-
0026538171
-
The metabolite morphine-6-glucuronide contributes to the analgesia produced by morphine infusion in patients with pain and normal renal function
-
Portenoy, R. K., H. T. Thaler, C. E. Inturrisi, H. Friedlander Klar & K. M. Foley: The metabolite morphine-6-glucuronide contributes to the analgesia produced by morphine infusion in patients with pain and normal renal function. Clin. Pharmacol. Therap. 1992, 51, 422-431.
-
(1992)
Clin. Pharmacol. Therap.
, vol.51
, pp. 422-431
-
-
Portenoy, R.K.1
Thaler, H.T.2
Inturrisi, C.E.3
Friedlander Klar, H.4
Foley, K.M.5
-
32
-
-
0022203284
-
Oral morphine in cancer patients: In vivo kinetics and in vitro hepatic glucuronidation
-
Säwe, J., L. Kager, J. O. Svensson Eng & A. Rane: Oral morphine in cancer patients: in vivo kinetics and in vitro hepatic glucuronidation. Brit. J. Clin. Pharmacol. 1985, 19, 495-501.
-
(1985)
Brit. J. Clin. Pharmacol.
, vol.19
, pp. 495-501
-
-
Säwe, J.1
Kager, L.2
Svensson Eng, J.O.3
Rane, A.4
-
33
-
-
0025006485
-
Morphine-3-glucuronide - A potent antagonist of morphine analgesia
-
Smith, M. T., J. A. Watt & T. Cramond: Morphine-3-glucuronide - a potent antagonist of morphine analgesia. Life Sci. 1990, 47, 579-585.
-
(1990)
Life Sci.
, vol.47
, pp. 579-585
-
-
Smith, M.T.1
Watt, J.A.2
Cramond, T.3
-
34
-
-
0027309202
-
Plasma concentrations and renal clearance of morphine, morphine-3-glucuronide and morphine-6-glucuronide in cancer patients receiving morphine
-
Somogyi, A. A., R. L. Nation, C. Olweny, P. Tsirgiotis, J. van Crugten, R. W. Milne, J. F. Cleary, C. Danz & F. Bochner: Plasma concentrations and renal clearance of morphine, morphine-3-glucuronide and morphine-6-glucuronide in cancer patients receiving morphine. Clin. Pharmacokin. 1993, 24, 413-420.
-
(1993)
Clin. Pharmacokin.
, vol.24
, pp. 413-420
-
-
Somogyi, A.A.1
Nation, R.L.2
Olweny, C.3
Tsirgiotis, P.4
Van Crugten, J.5
Milne, R.W.6
Cleary, J.F.7
Danz, C.8
Bochner, F.9
-
35
-
-
0027374701
-
Intrathecal morphine-3-glucuronide does not antagonize spinal antinociception by morphine or morphine-6-glucuronide in rats
-
Suzuki, N., E. Kalso & P. H. Rosenberg: Intrathecal morphine-3-glucuronide does not antagonize spinal antinociception by morphine or morphine-6-glucuronide in rats. Eur. J. Pharmacol. 1993, 249, 247-250.
-
(1993)
Eur. J. Pharmacol.
, vol.249
, pp. 247-250
-
-
Suzuki, N.1
Kalso, E.2
Rosenberg, P.H.3
-
36
-
-
0022588076
-
Determination of morphine, morphine-6-glucuronide and normorphine in plasma and urine with high-performance liquid chromatography and electrochemical detection
-
Svensson, J.: Determination of morphine, morphine-6-glucuronide and normorphine in plasma and urine with high-performance liquid chromatography and electrochemical detection. J. Chromatogr. 1986, 375, 174-178.
-
(1986)
J. Chromatogr.
, vol.375
, pp. 174-178
-
-
Svensson, J.1
-
37
-
-
0020309039
-
Determination of morphine, morphine-3-glucuronide and (tentatively) morphine-6-glucuronide in plasma and urine using ion-pair high-performance liquid chromatography
-
Svensson, J. O., A. Rane, J. Säwe & F. Sjöqvist: Determination of morphine, morphine-3-glucuronide and (tentatively) morphine-6-glucuronide in plasma and urine using ion-pair high-performance liquid chromatography. J. Chromatogr. 1982, 230, 427-432.
-
(1982)
J. Chromatogr.
, vol.230
, pp. 427-432
-
-
Svensson, J.O.1
Rane, A.2
Säwe, J.3
Sjöqvist, F.4
-
38
-
-
0026586861
-
Morphine 6-glucuronide: A metabolite of morphine with greater emetic potency than morphine in the ferret
-
Thompson, P. L. S. Bingham, P. L. Andrews, N. Patel, S. P. Joel & M. L. Slevin: Morphine 6-glucuronide: a metabolite of morphine with greater emetic potency than morphine in the ferret. Brit. J. Pharmacol. 1992, 106, 3-8.
-
(1992)
Brit. J. Pharmacol.
, vol.106
, pp. 3-8
-
-
Thompson, P.L.1
Bingham, S.2
Andrews, P.L.3
Patel, N.4
Joel, S.P.5
Slevin, M.L.6
-
39
-
-
0018902653
-
Effect of ethanol on glutathione concentration in isolated hepatocytes
-
Vina, J., J. M. Estrela, C. Guerri & F. J. Romero: Effect of ethanol on glutathione concentration in isolated hepatocytes. Biochem. J. 1980, 188, 549-552.
-
(1980)
Biochem. J.
, vol.188
, pp. 549-552
-
-
Vina, J.1
Estrela, J.M.2
Guerri, C.3
Romero, F.J.4
-
40
-
-
0029063116
-
Plasma concentrations of morphine, morphine-3-glucuronide, and morphine-6-glucuronide after intravenous and oral administration to healthy volunteers: Relationship to nonanalgesic actions
-
Westerling, D., C. Persson & P. Höglund: Plasma concentrations of morphine, morphine-3-glucuronide, and morphine-6-glucuronide after intravenous and oral administration to healthy volunteers: Relationship to nonanalgesic actions. Therap. Drug Monitoring 1995, 17, 287-301.
-
(1995)
Therap. Drug Monitoring
, vol.17
, pp. 287-301
-
-
Westerling, D.1
Persson, C.2
Höglund, P.3
|