Induction of cytochrome P450 2A6 expression in humans by the carcinogenic parasite infection, Opisthorchiasis viverrini

Cancer Epidemiology Biomarkers and Prevention

Volumn 5, Issue 10, 1996, Pages 795-800

  Satarug, Soisungwan ^a   Lang, Matti A ^b   Yongvanit, Puangrat ^a   Sithithaworn, Paiboon ^a   Mairiang, Eimorn ^a   Mairiang, Pisaln ^a   Pelkonen, Paivi ^b   Bartsch, Helmut ^c   Haswell Elkins, Melissa R ^a,d  

^a KHON KAEN UNIVERSITY   (Thailand)

^b INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d University of Queensland and Queensland Alliance for Environmental Health Sciences   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; PRAZIQUANTEL;

ADULT; ARTICLE; BILE DUCT CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVITY; FASCIOLIASIS; FEMALE; HUMAN; INTRAHEPATIC BILE DUCT; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; OPISTHORCHIASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANALYSIS OF VARIANCE; ANIMALS; ANTIPLATYHELMINTIC AGENTS; ARYL HYDROCARBON HYDROXYLASES; BILE DUCTS, INTRAHEPATIC; BIOLOGICAL MARKERS; CHOLANGIOCARCINOMA; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; FIBROSIS; HUMANS; LIVER DISEASES, PARASITIC; MALE; MIXED FUNCTION OXYGENASES; OPISTHORCHIASIS; PRAZIQUANTEL; RISK FACTORS; THAILAND;

EID: 0029858786     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Bartsch, B., and Montesano, R. Relevance of nitrosamines to human cancer. Carcinogenesis (Lond.), 5: 1381-1393, 1984.
2. Mirvish, S. S. Kinetics of dimethylamine nitrosation in relation to nitrosamine carcinogenesis. J. Natl. Cancer Inst., 44: 633-639, 1970.
3. Zeisel, S. H., and DaCosta, K-A. Increase in human exposure to methylamine precursors of N-nitrosamines after eating fish. Cancer Res., 46: 6136-6138, 1986.
4. Miwa, M., Steuhr, D. J., Marletta, M. A., Wishnok, J., and Tannenbaum, S. R. Nitrosation of amines by stimulated macrophages. Carcinogenesis (Lond.), 8: 955-958, 1987.
5. Leaf, C. D., Wishnok, J. S., and Tannenbaum, S. R. Mechanisms of endogenous nitrosation. Cancer Surv., 8: 323-334, 1989.
6. Ohshima, H., and Bartsch, H. Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis. Mut. Res., 305: 253-264, 1994.
7. Haswell-Elkins, M. R., Satarug, S., Tsuda, M., Mairiang, E., Esumi, H., Sithithaworn, P., Mairiang, P., Saitoh, M., Yongvanit, P., and Elkins, D. B. Liver fluke infection and cholangiocarcinoma: model of endogenous nitric oxide and extragastric nitrosation in human carcinogenesis. Mut. Res., 305: 241-252, 1994.
8. Ohshima, H., Bandaletova, T. Y., Brouet, I., Bartsch, H., Kirby, G., Ogunbiyi, F., Vatanasapt, V., and Pipitgool, V. Increased nitrosamine and nitrate biosynthesis mediated by nitric oxide synthase induced in hamsters infected with liver fluke (Opisthorchis viverrini). Carcinogenesis (Lond.), 15: 271-275, 1994.
9. Satarug, S., Haswell-Elkins, M. R., Tsuda, M., Mairiang, P., Sithithaworn, P., Mairiang, E., Esumi, H., Sukprasert, S., Yongvanit, P., and Elkins, D. B. Thiocyanate-independent nitrosation in humans with carcinogenic parasite infection. Carcinogenesis (Lond.), 17: 101-107, 1996.
10. Lai, D. Y., and Arcos, J. C. Dialkylnitrosamine bioactivation and carcinogenesis. Life Sci., 27: 2149-2165, 1980.
11. Guengerich, F. P., Kim, D. H., and Iwasaki, M. Role of human cytochrome P450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chem. Res. Toxicol., 4: 168-179, 1991.
12. Crespi, C. L., Penman, B. W., Leakey, J. A. E., Arlotto, M. P., Stark, A., Parkinson, A., Turner, T., Steimel, D. T., Rudo, K., Davies, R. L., and Langenbach, R. Human cytochrome P450IIA3: cDNA sequence, role in metabolic activation of promutagens, comparison to nitrosamine metabolism by human cytochrome P450IIE1. Carcinogenesis (Lond.), 11: 1293-1300, 1990.
13. Camus, A. M., Geneste, O., Honkakoski, P., Bereziat, J. C., Henderson, C. J., Wolf, C. R., Bartsch, H., and Lang, M. A. High variability of nitrosamine metabolism among individuals: role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitroso dimemylamine and N-nitroso diethylamine in mice and humans. Mol. Carcinog., 7: 268-274, 1993.
14. Kirby, G. M., Chemin, I., Montesano, R., Chisari, F. V., Lang, M. A., and Wild. C. P. Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice. Mol. Carcinog., 11: 74-80, 1994.
15. Kirby, G. M., Pelkonen, P., Vatanasapt, V., Camus, A-M., Wild, C. P., and Lang, M. A. Association of liver fluke (Opisthorchis viverrini) infestation with increased expression of cytochrome P450 and carcinogen metabolism in male, hamster liver. Mol. Carcinog., 11: 81-89, 1994.
16. Haswell-Elkins, M. R., Satarug, S., and Elkins, D. B. Opisthorchis viverrini in Northeast Thailand and its relationship to cholangiocarcinoma. J. Gastroenterol. Hepatol., 7: 538-548, 1992.
17. Sriamporn, S. Epidemiologic study of liver cancer using a population-based cancer registry as a guide in Khon Kaen, Thailand. Hlth. Rep., 5: 51-58, 1993.
18. Haswell-Elkins, M. R., Mairiang, E., Mairiang, P., Chaiyakum, J., Chamadol, N., Laopaiboon, V., Sithithaworn, P., and Elkins, D. B. Cross-sectional study of Opisthorchis viverrini infection and cholangiocarcinoma in communities within a high risk area in Northeast Thailand. Int. J. Cancer, 59: 505-509, 1994.
19. Peter, R., Bocker, R., Beaune, P. H., Iwasaki, M., Guengerich, F. P., and Yang, C. S. Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P450IIE1. Chem. Res. Toxicol, 3: 566-573, 1990.
20. Rautio, A., Kraul, H., Kojo, A., Salmela, E., and Pelkonen, O. Interindividual variability of coumarin 7-hydroxylation in healthy volunteers. Pharmacogenetics, 2: 227-233, 1992.
21. Mairiang, E., Elkins, D. B., Mairiang, P., Chaiyakum, J., Chamadol, N., Loapaiboon, V., Posri, S., Sithithaworn, P., Haswell-Elkins, M. R. Relationship between intensity of Opisthorchis viverrini infection and hepatobiliary disease detected by ultrasonography. J. Gastroenterol. Hepatol., 7: 17-21, 1992.
22. Elkins, D. B., Mairiang, E., Sithithaworn, P., Mairiang, P., Chaiyakum, J., Chamadol, N., Loapaiboon, V., and Haswell-Elkins, M. R. Cross sectional patterns of possible precursor conditions of cholangiocarcinoma associated with Opisthorchis viverrini infection in humans. Am. J. Trop. Med. Hyg., in press, 1996.
23. Tekwani, B. L., Shulka, O. P., and Ghatak, S. Altered drug metabolism in parasitic diseases. Parasitol. Today, 4: 4-10, 1988.
24. Haswell-Elkins, M. R., Sithithawom, P., Mairiang, E., Elkins, D. B., Wongratanacheewin, S., Kaewkes, S., and Mairiang, P. Immune responsiveness and parasite-specific antibody levels in human hepatobiliary disease associated with Opisthorchis viverrini infection. Clin. Exp. Immunol., 84: 213-218, 1991.
25. Fernando-Salguero, P., Hoffman, S. M. G., Cholerton, S., Mohrenweiser, H., Raunio, H., Rautio, A., Pelkonen, O., Huang, J., Evans, W. E., Idle, J. R., and Gonzalez, F. J. A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles. Am. J. Hum. Genet., 57: 651-660, 1995.