Structural and functional characterization of vitronectin-derived RGD-containing peptides from human hemofiltrate

European Journal of Biochemistry

Volumn 241, Issue 2, 1996, Pages 557-563

  Ständker, Ludger ^a   Enger, Andreas ^b   Schulz Knappe, Peter ^a   Wohn, Karl Dieter ^b   Germer, Matthias ^b   Raida, Manfred ^a   Forssmann, Wolf Georg ^a   Preissner, Klaus T ^b  

^a IPF PHARMACEUTICALS GMBH   (Germany)

^b KERCKHOFF HEART CENTER   (Germany)

Author keywords

Hemofiltrate; Integrin; Plasminogen activator inhibitor 1; Somatomedin B peptide; Vitronectin

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; INTEGRIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; VITRONECTIN;

ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; ESCHERICHIA COLI; EXTRACELLULAR MATRIX; GENE CONSTRUCT; GENE EXPRESSION; HEMOFILTRATION; HUMAN; HUMAN TISSUE; KIDNEY DISEASE; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; DNA PRIMERS; HEMOFILTRATION; HUMANS; KIDNEY FAILURE, CHRONIC; MOLECULAR STRUCTURE; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; VITRONECTIN;

ESCHERICHIA COLI; RUTA;

EID: 0029858628     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.00557.x     Document Type: Article

References (37)

1. O'Reilly, M. S., Holmgren, L., Shing, Y., Chen, C., Rosenthal, R. A., Moses, M., Lane, W. S., Cao, Y., Sage, E. H. & Folkman, J. (1994) Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79, 315-328.
2. Hugli, T. E. (1981) The structural basis for anuphylutoxin and chemotatic functions of C3a, C4a and C5a, CRC. Crit. Rev. Immunol. 2, 321-351.
3. Ständker, L., Sillard, R., Bensch, K. W., Ruf, A., Raida, M., Schulz-Knappe, P., Schepky. A. G., Patscheke, H. & Forssmann, W. G. (1995) In vivo degradation of fibrinogen Aα: detection of cleavage sites and release of antithrombotic peptides. Biochem. Biophys. Res. Commun. 215, 896-902.
4. Bensch, K. W., Raida, M., Magert, H. J., Schulz-Knappe, P. & Forssmann, W. G. (1995) hBD-1: a novel β-defensin from human plasma, FEBS Lett. 368, 331-335.
5. Hess, R., Kuhn, M., Schulz-Knappe, P., Raida, M., Fuchs, M., Klodt, J., Adermann, K., Kaever, V., Cetin, Y. & Forssmann, W. G. (1995) GCAP-II: isolation and characterization of the circulating form of human uroguanylin. FEBS Lett. 374, 34-38.
6. Schulz-Knappe. P., Mägert, H. J., Dewald, B., Meyer, M., Cetin, Y., Kubbies, M., Tomeczkowski, J., Kirchhoff, K., Raida, M., Adermann, K., Kist, A., Reinecke, M., Sillard, R., Pardigol. A., Uguccioni, M., Baggiolini, M. & Forssmann, W. G. (1996) HCC-1, a novel chemokine from human plasma. J. Exp. Med. 183, 295-299.
7. Forssmann, W. G., Schulz-Knappe, P., Meyer, M., Adermann, K., Forssmann, K., Hock, D. & Aoki, A. (1993) New peptides from human hemofiltrate, in Peptide chemistry (Yanaihara, N., ed.) p. 553, ESCOM Science Publishers, Leiden.
8. Schulz-Knappe, P., Raida, M., Meyer, M. & Forssmann, W. G. (1996) Systematic isolation of circulating human peptides: the concept of peptide trapping, Eur. J. Med. Res. 1, 223-236.
9. Preissner, K. T. & Jenne, D. (1991) Structure of vitronectin and its biological role in haemostasis, Thromb. Haemostasis 66, 123-130.
10. Tomasini, B. R. & Mosher, D. F. (1990) Vitronectin, Prog. Hemostasis Thromb. 10, 269-305.
11. Preissner, K. T. (1991) Structure and biological role of vitronectin, Annu. Rev. Cell. Biol. 7, 275-310.
12. Seiffert, D. & Loskutoff, D. J. (1991) Evidence that type-1 plasminogen activator inhibitor binds to the somatomedin-B domain of vitronectin, J. Biol. Chem. 266, 2824-2830.
13. Declerck, P. J., De Mol, M., Alessi, M.-C., Baudner, S., Paques, E.-P., Preissner, K. T., Muller-Berghaus, G. & Collen, D. (1988) Purification and characterization of a plasminogen activator inhibitor I binding protein from human plasma. Identification as a nultimeric form of S protein (vitronectin), J. Biol. Chem. 263, 15454-15461.
14. Mimuro, J. & Loskutoff, D. J. (1989) Binding of type 1 plasminogen activator inhibitor to the extracellular matrix of cultured bovine endothelial cells. J. Biol. Chem. 264, 5058-5063.
15. Preissner, K. T., Grulich-Henn, J., Ehrlich, H. J., Declerck, P., Justus, C., Collen, D., Pannekoek, H. & Müller-Berghaus, G. (1990) Structural requirements for the extracellular interaction of plasminogen activator inhibitor I with endothelial cell matrix-associated vitronectin, J. Biol. Chem. 265, 18490-18498.
16. Declerck, P. J., Alessi, M.-C., Verstreken, M., Kruithof, E. K. O., Juhan-Vague, I. & Collen, D. (1988) Measurement of plasminogen activator inhibitor 1 in biologic fluids with a murine monoclonal antibody-based enzyme-linked immunosorbent assay, Blood 71, 220-225.
17. Jenne, D. & Stanley, K. K. (1985) Molecular cloning of S-protein, a link between complement, coagulation and cell-substrate adhesion. EMBO J. 4, 3153-3157.
18. Bradford, M. M. (1976) A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the protein-dye binding. Anal. Biochem. 72, 234-254.
19. Sancho, E., Tonge, D. W., Hockney, R. C. & Booth, N. A. (1994) Purification and characterization of active and stable recombinant plasminogen-activator inhibitor accumulated at high levels in Escherichia coli, Eur. J. Biochem. 224, 125-134.
20. Kost, C., Stüber, W., Ehrlich, H., Pannekoek, H. & Preissner, K. T. (1992) Mapping of binding sites for heparin, plasminogen-activator inhibitor-1 and plasminogen to vitronectin's heparin binding region reveals a novel vitronectin-dependent feedback mechanism for the control of plasmin formation, J. Biol. Chem. 267, 12098-12105.
21. Preissner, K. T., Wassmuth, R. & Müller-Berghaus, G. (1985) Physicochemical characterization of human S-protein and its function in the blood coagulation system, Biochem. J. 231, 349-355.
22. Mitjans, F., Sander, D., Adan, J., Sutter, A., Martinez, J. M., Jäggle, C., Moyano, J. M., Kreysch, H., Piulats, J. & Goodman, S. L. (1995) An anti-av-integrin antibody that blocks integrin function inhibits the development of a human melanoma in nude mice, J. Cell. Sci. 108, 2825-2838.
23. Kanse, S. M., Kost, C., Wilhelm, O. G., Andreasen, P. A. & Preissner, K. T. (1996) The urokinase receptor is a major vitronectin binding protein on endothelial cells, Exp. Cell Res. 224, 344-353.
24. Fryklund, L., Uthne, K. & Sievertsson, H. (1974) Isolation and characterization of polypeptides from human plasma enhancing the growth of human normal cells in culture, Biochem. Biophys. Res. Commun. 61, 950-956.
25. Fryklund, L. & Sievertsson, H. (1978) Primary structure of somatomedin B. A growth hormone-dependent serum factor with protease inhibiting activity, FEBS Lett. 87, 55-60.
26. Heldin, C.-H., Wasteson, A., Fryklund, L. & Westermark, B. (1981) Somatomedin B: mitogenic activity derived from contaminant epidermal growth factor. Science 213, 1122-1123.
27. Merberg, D. M., Fitz, L. J., Temple, P., Giannotti, J., Murtha, P., Fitzgerald, M., Scaltreto. H., Kelleher, K., Preissner, K. T., Kriz, R., Jakobs, K. & Turner, K. (1993) A comparison of vitronectin and megakaryocyte stimulating factor, in Biology of vitronectins and their receptors (Preissner, K. T., Rosenblatt, S., Wegerhoff, J., Kost, C. & Mosher, D. F., eds) pp. 45-53, Elsevier, Amsterdam.
28. Seiffert, D., Ciambrone, G., Wagner, N. V., Binder, B. R. & Loskutoff, D. J. (1994) The somatomedin B domain of vitronectin. Structural requirements for the binding and stabilization of active type 1 plasminogen activator inhibitor, J. Biol. Chem. 269, 2659-2666.
29. Yalow, R. S., Hall, K. & Luft, R. (1975) Radioimmunoassay of somatomedin B. Application to clinical and physiologic studies, J. Clin. Invest. 55, 127-137.
30. Wajchenberg, B. L., Liberman, B., Gomes, E. N. D. S. & Pieroni, R. R. (1980) Radio-immuno-assayable serum somatomedin B in normal subjects and in patients with acromegaly and pituitary dwarfism: effects of human growth hormone therapy, Horm. Metab. Res. 12, 516-519.
31. Kramer, M. D., Gissler, H. M., Weidenthaler-Barth, B. & Preissner, K. T. (1993) Vitronectin and plasmin(ogen) in lesional skin of the bullous pemphigoid: colocalisation suggests binding interactions, in Biology of vitronectins and their receptors (Preissner. K. T., Rosenblatt, S., Kost, C., Wegerhoff, J. & Mosher, D. F., eds) pp. 295-301, Eisevier, Amsterdam.
32. Casaroli Marano, R. P., Preissner, K. T. & Vilaro, S. (1995) Fibronectin, laminin, vitronectin and their receptors at newly-formed capillaries in proliferative diabetic retinopathy, Exp. Eye Res. 60, 5-17.
33. Sane, D. C., Moser, T. L. & Greenberg, C. S. (1991) Limited proteolysis of vitronectin by plasmin destroys heparin binding activity, Thromb. Haemostasis 66, 310-314.
34. Kost, C., Benner, K., Stockmann, A., Linder, D. & Preissner, K. T. (1996) Limited plasmin proteolysis of vitronectin: characterization of the adhesion protein as morpho-regulatory and angiostutin-binding factor, Eur. J. Biochem. 236, 682-688.
35. Seiffert, D. (1996) Hydrolysis of platelet vitronectin by calpain. J. Biol. Chem. 271, 11170- 11176.
36. Preissner, K. T., Holzhüter, S., Justus, C. & Müller-Berghaus, G. (1989) Identification and partial characterization of platelet vitronectin: Evidence for complex formation with platelet-derived plasminogen-activator inhibitor-1. Blood 74, 1989-1996.
37. Wei, Y., Waltz, D. A., Rao, N., Drummond, R. J., Rosenberg, S. & Chapman, H. A. (1994) Identification of the urokinase receptor as an adhesion receptor for vitronectin, J. Biol. Chem. 269, 32380-32388.