Protein tyrosine phosphorylation in leukocyte activation through receptors for IgG

Journal of Leukocyte Biology

Volumn 60, Issue 4, 1996, Pages 433-440

  Santana, Carla ^a   Noris, Gino ^a   Espinoza, Bertha ^a   Ortega, Enrique ^a,b  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b INSTITUTO DE INVESTIGACIONES BIOMÉDICAS   (Mexico)

Author keywords

Fc R; Hematopoietic cells; Transmembrane signaling

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN G; TYROSINE;

CELL MEMBRANE; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

EID: 0029858537     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.60.4.433     Document Type: Review

References (74)

1. Ravetch, J. V., Kinet, J. P. (1991) Fc receptors. Annu. Rev. Immunol. 9, 457-492.
2. Capel, P. J. A., van de Winkel, J. G. J., van den Herik-Oudijk, I. E., Verbeek, J. S. (1994) Heterogeneity of human IgG Fc receptors. Immunomethods 4, 25-34.
3. Hulett, M. D., Hogart, P. M. (1994) Molecular basis of Fc receptor function. Adv. Immunol. 57, 1-127.
4. Ravetch, J. V., Anderson, C. L. (1990) FcγR family: proteins, transcripts and genes. In Fc Receptors and the Action of Antibodies (H. Metzger, ed.) Washington, DC, Am. Soc. Microbiol., 211-235.
5. Durden, D. L., Rosen, H., Michel, B. R., Cooper, J. A. (1994) Protein tyrosine phosphatase inhibitors block myeloid signal transduction through the FcγRI receptor. Exp. Cell Res. 211, 150-162.
6. Daeron, M., Malbec, O., Latour, S., Bonnerot, C., Segal, D. M., Fridman, W. H. (1993) Distinct intracytoplasmic sequences are required for endocytosis and phagocytosis via murine FcγRII in mast cells. Int. Immunol. 5, 1393-1401.
7. Indik, Z. K., Park, J. G., Pan, X. Q., Schreiber, D. (1995) Induction of phagocytosis by a protein tyrosine kinase. Blood 85, 1175-1180.
8. Segal, D. M. (1990) Antibody-mediated killing by leukocytes. In Fc Receptors and the Action of Antibodies (H. Metzger, ed.) Washington, DC, Am. Soc. Microbiol., 291-301.
9. Reth, M. (1989) Antigen receptor tail clue. Nature [Lond.] 338, 383-384.
10. Clark, M. R., Johnson, S. A., Cambier, J. C. (1994) Analysis of Ig-α tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-α stimulation of Fyn activity. Eur. Mol. Biol. Org. J. 13, 1911-1919.
11. Shiue, L., Zoller, M. J., Brugge, J. S. (1995) Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE. J. Biol. Chem. 270, 10498-10502.
12. Rowley, R. B., Burkhardt, A. L., Chao, H. G., Matsueda, C. R., Bolen, J. B. (1995) Syk protein tyrosine kinase is regulated by tyrosine phosphorylated Igα/Igβ immunoreceptor tyrosine activation motif binding and autophosphorylation. J. Biol. Chem. 270, 11590-11594.
13. Kinet, J. P. (1992) The γ-ζ dimers of Fc receptors as connectors to signal transduction. Curr. Op. Immunol. 4, 43-48.
14. Azzoni, L., Kamoun, M., Salcedo, T. W., Kanakaraj, P., Perussia, B. (1992) Stimulation of FcγRIIIA results in phospholipase C-γ1 tyrosine phosphorylation and p56lck activation. J. Exp. Med. 176, 1745-1750.
15. Ting, A. T., Einspahr, K. J., Abraham, R. T., Leibson, P. J. (1991) Fcγ receptor transduction in natural killer cells. J. Immunol. 147, 3122-3127.
16. Wirthmueller, U., Kurosaki, T., Murakami, M. S., Ravetch, J. V. (1992) Signal transduction by FcγRIII (CD16) is mediated through the γ chain. J. Exp. Med. 175, 1381-1390.
17. Einspahr, K. J., Abraham, R. T., Binstadt, B. A., Uehara, Y., Leibson, P. J. (1991) Tyrosine phosphorylation provides an early and requisite signal for the activation of natural killer cell cytotoxic function. Proc. Natl. Acad. Sci. USA 88, 6279-6283.
18. O'Shea, J. J., Weissman, A. M., Kennedy, I. C. S., Ortaldo, J. R. (1991) Engagement of the natural killer cell IgG Fc receptor results in tyrosine phosphorylation of the ζ chain. Proc. Natl. Acad. Sci. USA 88, 350-354.
19. O'Shea, J. J., McVicar, D. W., Kuhns, D. B., Ortaldo, J. R. (1992) A role for protein tyrosine kinase activity in natural killer cytotoxicity as well as antibody-dependent cellular cytotoxicity. J. Immunol. 148, 2497-2502.
20. Vivier, E., Morin, P., O'Brien, C., Druker, B., Schlossman, S. F., Anderson, P. (1991) Tyrosine phosphorylation of the FcγRIII(CD16):ζ complex in human natural killer cells. J. Immunol. 146, 206-210.
21. Stahls, A., Heiskala, M., Mustelin, T., Andersson, L. C. (1992) Activation of natural killer cells via the FcγRIII (CD16) requires initial tyrosine phosphorylation. Eur. J. Immunol. 22, 611-614.
22. Cone, J. C., Lu, Y., Trevillyan, J. M., Bjorndahl, J. M., Phillips, C. A. (1993) Association of the p56 lck protein tyrosine kinase with the FcγRIIIA/CD16 complex in human natural killer cells. Eur. J. Immunol. 23, 2488-2497.
23. Salcedo, T. W., Kurosaki, T., Kanakaraj, P., Ravetch, J. V., Perussia, B. (1993) Physical and functional association of p56lck with FcγRIIIA (CD16) in natural killer cells. J. Exp. Med. 177, 1475-1480.
24. Masuda, M., Verhoeven, A. J., Roos, D. (1993) Tyrosine phosphorylation of a γ-chain homodimer associated with FcγRIII (CD16) in cultured human monocytes. J. Immunol. 151, 6382-6388.
25. Greenberg, S., Chang, P., Silverstein, S. C. (1994) Tyrosine phosphorylation of the γ subunit of Fcγ receptors, p72syk, and paxillin during Fc receptor mediated phagocytosis in macrophages. J. Biol. Chem. 269, 3897-3902.
26. Bonnerot, C., Amignorena, S., Choquet, D., Pavlovich, R., Choukroun, V., Fridman, W. H. (1992) Role of associated γ-chain in tyrosine kinase activation via murine FcγRIII. Eur. Mol. Biol. Org. J. 11, 2747-2757.
27. Park, J. G., Murray, R. K., Chien, P., Darby, C., Schreiber, A. D. (1993) Conserved cytoplasmic tyrosine residues of the γ subunit are required for a phagocytic signal mediated by FcγRIIIA. J. Clin. Invest. 92, 2073-2079.
28. Vivier, E., Rochet, N., Ackerly, M., Petrini, J., Levine, H., Daley, J., Anderson, P. (1992) Signaling function of reconstituted CD16:ζ:γ receptor complex isoforms. Int. Immunol. 4, 1313-1323.
29. Kanakaraj, P., Duckworth, B., Azzoni, L., Kamoun, M., Cantley, L. C., Perussia, B. (1994) Phosphatidylinositol-3 kinase activation induced upon FcγRIIIA-ligand interaction. J. Exp. Med. 179, 551-558.
30. Ting, A. T., Karnitz, L. M., Schoon, R. A., Abraham, R. T., Leibson, P. J. (1992) Fcγ receptor activation induces the tyrosine phosphorylation of both phospholipase C (PLC)-γ1 and PLC-γ2 in natural killer cells. J. Exp. Med. 176, 1751-1755.
31. Liao, F., Shin, H. S., Rhee, S. G. (1993) Crosslinking of FcγRIIIA on natural killer cells results in tyrosine phosphorylation of PLC-γ1 and PLC-γ2. J. Immunol. 150, 2668-2674.
32. Darby, C., Geahlen, R. L., Schreiber, A. D. (1994) Stimulation of macrophage FcγRIIIA activates the receptor-associated protein tyrosine kinase Syk and induces phosphorylation of multiple proteins including p95Vav and P62/GAP associated protein. J. Immunol. 152, 5429-5437.
33. Richard, S., Shaw, A. S., Showell, H. J., Connelly, P. A. (1994) The role of individual Fcγ receptors in aggregated IgG-stimulated protein tyrosine phosphorylation in the human neutrophil. Biochem. Biophys. Res. Commun. 199, 653-661.
34. Hulett, M. D., Osman, N., McKenzie, I. F. C., Hogart, P. M. (1991) Chimeric Fc receptors identify functional domains of the murine FcγRI high affinity receptor for IgG. J. Immunol. 147, 1863-1868.
35. Ernst, L. K., Duchemin, A. M., Anderson, C. L. (1993) Association of the high affinity receptor for IgC (FcγRI) with the γ subunit of the IgE receptor. Proc. Natl. Acad. Sci. USA 90, 6023-6027.
36. Scholl, P. R., Geha, R. S. (1993) Physical association between the high affinity IgG receptor (FcγRI) and the γ subunit of the IgE receptor. Proc. Natl. Acad. Sci. USA 90, 8847-8850.
37. Masuda, M., Roos, D. (1993) Association of all three types of FcγR (CD64, CD32, and CD16) with a γ-chain homodimer in cultured human monocytes. J. Immunol. 151, 7188-7195.
38. Durden, D. L., Rosen, H., Cooper, J. A. (1994) Serine/threonine phosphorylation of the γ-subunit after activation of the high affinity Fc receptor for immunoglobulin G. Biochem. J. 299, 569-577.
39. Indik, Z. K., Hunter, S., Huang, M. M., Pan, X. Q., Chien, P., Kelly, C., Levinson, A. I., Kimberly, R. P., Schreiber, A. D. (1994) The high affinity Fcγ receptor (CD64) induces phagocytosis in the absence of its cytoplasmic domain: the γ subunit of FcγRIIIA imparts phagocytic function to FcγRI. Exp. Hematol. 22, 599-606.
40. Davis, W., Harrison, P. T., Hutchinson, M. J., Allen, J. M. (1995) Two distinct regions of FcγRI initiate separate signaling pathways involved in endocytosis and phagocytosis. Eur. Mol. Biol. Org. J. 14, 423-441.
41. Hutchinson, M. J., Harrison, P. T., Floto, R. A., Allen, J. M. (1995) Fcγ receptor-mediated phagocytosis requires tyrosine kinase activity and is ligand independent. Eur. J. Immunol. 25, 481-487.
42. Scholl, P. R., Ahern, D., Geha, R. S. (1992) Protein tyrosine phosphorylation induced via the IgG receptors FcγRI and FcγRII in the human monocytic cell line THP-1. J. Immunol. 149, 1751-1757.
43. Rankin, B. M., Yocum, S. A., Mittler, R. S., Kiener, P. A. (1993) Stimulation of tyrosine phosphorylation and calcium mobilization by Fcγ receptor crosslinking. J. Immunol. 150, 605-616.
44. Kiener, P. A., Rankin, B. M., Burkhardt, A. L., Schieven, G. L., Gilliland, L. K., Rowley, R. B., Bolen, J. B., Ledbetter, J. A. (1993) Crosslinking of Fcγ receptor I (FcγRI) and receptor II (FcγRII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase. J. Biol. Chem. 268, 24442-24448.
45. Liao, F., Shin, H. S., Rhee, S. G. (1992) Tyrosine phosphorylation of phospholipase C-γ1 induced by crosslinking of the high or low affinity Fc receptor for IgG in U937 cells. Proc. Natl. Acad. Sci. USA 89, 3659-3663.
46. Ninomiya, N., Hazeki, K., Fukui, Y., Seya, T., Okada, T., Hazeki, O., Ui, M. (1994) Involvement of phosphatidylinositol 3-kinase in Fcγ receptor signaling. J. Biol. Chem. 269, 22732-22737.
47. Cassel, D. L., Keller, M. A., Surrey, S., Schwartz, E., Schreiber, A. D., Rappaport, E. F., McKenzie, S. E. (1993) Differential expression of FcγRIIA, FcγRIIB, and FcγRIIC in hematapoietic cells: analysis of transcripts. Mol. Immunol. 30, 451-460.
48. Liu, Z., Pudiak, D., Looney, R. J. (1994) Protein tyrosine phosphorylation triggered by human FcγRII. Biochem. Biophys. Res. Commun. 201, 829-834.
49. Indik, Z. K., Pan, X. Q., Huang, M. M., McKenzie, S. E., Levinson, A. I., Schreiber, A. D. (1994) Insertion of cytoplasmic tyrosine sequences into the nonphagocytic receptor FcγRIIB establishes phagocytic function. Blood 83, 2072-2080.
50. Mitchell, M. A., Huang, M. M., Chien, P., Indik, Z. K., Pan, Q. X., Schreiber, A. D. (1994) Substitutions and deletions in the cytoplasmic domain of the phagocytic receptor FcγRIIA: effect on receptor tyrosine phosphorylation and phagocytosis. Blood 84, 1753-1759.
51. Van den Herik-Oudikj, I. E., Capel, P. J., van der Bruggen, T., Van de Winkel, J. G. (1995) Identification of signaling motifs within human FcγRIIa and FcγRIIb isoforms. Blood 85, 2202-2211.
52. D'Ambrosio, D., Hippen, K. L., Miskoff, S. A., Mellman, I., Pani, G., Siminovitch, K. A., Cambier, J. C. (1995) Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by FcγRIIb1. Science 268, 293-297.
53. Indik, Z. K., Park, J. G., Hunter, S., Schreiber, A. D. (1995) The molecular dissection of Fcγ receptor mediated phagocytosis. Blood 86, 4389-4399.
54. Park, J. C., Schreiber, A. D. (1995) Determinants of the phagocytic signal mediated by the type IIIA Fc gamma receptor, FcγRIIIA: sequence requirements and interaction with protein tyrosine kinases. Proc. Natl. Acad. Sci. USA 92, 7381-7385.
55. Clark, M. R., Campbell, K. S., Kazlauskas, A., Johnson, S. A., Hertz, M., Potter, T. A., Pleinman, C., Cambier, J. C. (1992) The B cell antigen receptor complex. Association of Ig-α and Ig-β with distinct cytoplasmic effectors. Science 258, 123-126.
56. Kihara, H., Siraganian, R. P. (1994) Src homology 2 domains of Syk and Lyn bind to tyrosine-phosphorylated subunits of the high affinity IgE receptor. J. Biol. Chem. 269, 22427-22432.
57. Hunter, S., Huang, M. M., Indik, Z. K., Schreiber, A. D. (1993) FcγRIIA-mediated phagocytosis and receptor phosphorylation in cells deficient in the protein tyrosine kinase Src. Exp. Hematol. 21, 1492-1497.
58. Durden, D. L., Kim, H. M., Calore, B., Liu, Y. (1995) The FcγRI signals through the activation of hck and MAP kinase J. Immunol. 154, 4039-4047.
59. Wang, A. V., Scholl, P. R., Geha, R. S. (1994) Physical and functional association of the high affinity immunoglobulin G receptor (FcγRI) with the kinases Hck and Lyn. J. Exp. Med. 180, 1165-1170.
60. Agarwal, A., Salem, P., Robbins, K. C. (1993) Involvement of p72syk, a protein tyrosine kinase, in Fcγ receptor signaling. J. Biol. Chem. 268, 15900-15905.
61. Durden, D. L., Liu, Y. B. (1994) Protein tyrosine kinase p72syk in FcγRI receptor signaling. Blood 84, 2102-2108.
62. Duchemin, A. M., Ernst, L. K., Anderson, C. L. (1994) Clustering of the high affinity Fc receptor for immunoglobulin G (FcγRI) results in phosphorylation of its associated γ chain. J. Biol. Chem. 269, 12111-12117.
63. Pignata, C., Prasad, K. V. S., Robertson, M. J., Levine, H., Rudd, C. E., Ritz, J. (1993) FcγRIIIA mediated signaling involves Src-family lck in human natural killer cells. J. Immunol. 151, 6794-6800.
64. Vivier, E., da Silva, A. J., Ackerly, M., Levine, H., Rudd, C. E., Anderson, P. (1993) Association of a 70-kDa tyrosine phosphoprotein with the CD16:ζ:γ complex expressed in human natural killer cells. Eur. J. Immunol. 23, 1872-1876.
65. Stahls, A., Liwszyc, G. E., Couture, C., Mustelin, T., Andersson, L. C. (1994) Triggering of human natural killer cells through CD16 induces tyrosine phosphorylation of the p72syk kinase. Eur. J. Immunol. 24, 2491-2496.
66. Ghazizadeh, S., Bolen, J. B., Fleit, H. B. (1994) Physical and functional association of Src-related protein tyrosine kinases with FcγRII in monocytic THP-1 cells. J. Biol. Chem. 269, 8878-8884.
67. Ghazizadeh, S., Fleit, H. B. (1994) Tyrosine phosphorylation provides an obligatory early signal for FcγRII mediated endocytosis in the monocytic cell line THP-1. J. Immunol. 152, 30-41.
68. Liang, L., Huang, C. K. (1995) Tyrosine phosphorylation induced by crosslinking of Fcγ receptor type II in human neutrophils. Biochem. J. 306, 489-495.
69. Ghazizadeh, S., Bolen, J. B., Fleit, H. B. (1995) Tyrosine phosphorylation and association of Syk with FcγRII in monocytic THP-1 cells. Biochem. J. 305, 669-674.
70. Hamada, F., Aoki, M., Akiyama, T., Toyoshima, K. (1993) Association of immunoglobulin G Fc receptor II with Src-like protein tyrosine kinase Fgr in neutrophils. Proc. Natl. Acad. Sci. USA 90, 6305-6309.
71. Sarmay, G., Pecht, I., Gergely, J. (1994) Protein tyrosine kinase activity tightly associated with human type II Fcγ receptors. Proc. Natl. Acad. Sci. USA 91, 4140-4144.
72. Huang, M., Indik, Z., Brass, L. F., Hoxie, J. A., Schreiber, A. D., Brugge, J. S. (1992) Activation of FcγRII induces tyrosine phosphorylation of multiple proteins including FcγRII. J. Biol. Chem. 267, 5467-5473.
73. Blake, R. A., Asselin, J., Walker, T., Watson, S. P. (1994) FcγR II stimulated formation of inositol phosphates in human platelets is blocked by tyrosine kinase inhibitors and associated with tyrosine phosphorylation of the receptor. FEBS Lett. 3425, 15-18.
74. Chacko, G. W., Duchemin, A. M., Coggeshall, K. M., Osborne, J. M., Brandt, J. T., Anderson, C. L. (1994) Clustering of the platelet Fcγ receptor induces noncovalent association with the tyrosine kinase p72syk. J. Biol. Chem. 269, 32435-32440.