The three-dimensional structure of bovine odorant binding protein and its mechanism of odor recognition

Nature Structural Biology

Volumn 3, Issue 11, 1996, Pages 934-939

  Bianchet, Mario A ^a   Bains, Gabrielle ^a   Pelosi, Paolo ^a   Pevsner, Jonathan ^b,c   Snyder, Solomon H ^b   Monaco, Hugo L ^d   Amzel, L Mario ^a  

^a UNIVERSITY OF PISA   (Italy)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c KENNEDY KRIEGER INSTITUTE   (United States)

^d UNIVERSITY OF PAVIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN;

ARTICLE; BINDING SITE; CATTLE; NONHUMAN; NOSE MUCOSA; ODOR; OLFACTORY DISCRIMINATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

ALPHA-GLOBULINS; ANIMALS; BINDING SITES; CATTLE; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ODORS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ODORANT; SELENIUM; SMELL;

BOS TAURUS; BOVINAE; MAMMALIA;

EID: 0029858390     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb1196-934     Document Type: Article

References (34)

1. Pelosi, P. Odorant binding proteins. Crit. Rev. Biochem. Molec. Biol. 29, 199-228 (1994).
2. Snyder, S.H., Sklar, P.B. & Pevsner, J. Molecular mechanisms of olfaction. J. Biol. Chem. 263, 13971-13974 (1988).
3. Pevsner, J., Reed R.R., Feinstein, P.G. & Snyder, S.H. Molecular cloning of odorant-binding protein: member of a ligand carrier family. Science 241, 336-339 (1988).
4. Pelosi, P. & Tirindelli, R. Structure/activity studies and characterization of an odorant-binding protein. In: Chemical Senses, Vol 1. Receptor Events and Transduction in Taste and Olfaction. (Eds J.G. Brand, J.H. Teeter, R.H. Cagan, & M.R. Kare) 207-225 (Marcel Dekker, New York, 1989).
5. Pevsner, J., Hou, V., Snowman, A.M. & Snyder, S.H. Odorant-binding protein, characterization of ligand binding. J. Biol. Chem. 265, 6118-6125 (1990).
6. Tirindelli, R., Keen, N.J., Cavaggioni, A., Eliopoulos E.E. & Findlay, J.B.C. Complete amino acid sequence of pyrazine-binding protein from cow nasal mucosa. Eur. J. Biochem. 185, 569-572 (1989).
7. Cowan, S.W., Newcomer, M.E. & Jones, T.A. Crystallographic refinement of human serum retinol binding protein at 2 Å resolution. Proteins 8, 44 (1990).
8. Zanotti, G., Berni, R. & Monaco, H.L. Crystal structure of liganded and unliganded forms of bovine plasma retinol-binding protein. J. Biol. Chem. 268, 10728-10738 (1993).
9. Papiz, M.Z. et al. The structure of β lactoglobulin and its similarity to plasma retinol-binding protein. Nature 324, 383-385 (1986).
10. Monaco, H.L. et al. Crystal structure of the trigonal form of bovine beta lactoglobulin and of its complex with retinol at 2.5 A resolution. J. Mol. Biol. 197, 695-706 (1987).
11. Holden, H.M., Rypniewski, W.R., Law, J.H. & Rayment, I. The molecular structure of insecticyanin from tobacco hornworm Manduca sexta L. at 2.6 A resolution. EMBO J. 6, 1565-1570 (1987).
12. Huber, R. et al. Crystallization, crystal structure analysis and preliminary molecular model of the bilin binding protein from the insect Pieris brassicae. J. Mol. Biol. 195, 423-434 (1987).
13. Huber, R. et al. Molecular structure of the bilin binding protein (BBP) from Pieris brassicae after refinement at 2.0 Å resolution. J. Mol. Biol. 198, 499-513 (1987).
14. Bocskel, Z. et al. Pheromone binding to two rodent urinary proteins revealed by X-ray crystallography. Nature 360, 186-188 (1992).
15. Bennett, M.J., Schlunegger, M.P. & Eisenberg, D. 3D Domain swapping: A mechanism for oligomer assembly. Prot. Sci. 4, 2455-2468 (1995).
16. Green, S.M., Gittis, A.G., Meeker, A.K. & Lattman, E.E. One-step evolution of a dimer from a monomeric protein. Nature Struct. Biol. 2, 746-751 (1995).
17. Monaco, H.L. & Zanotti, G. The three dimensional structure of three hydrophobic molecule-binding proteins with significant amino acid sequence similarity. Biopolymers 32, 457-465 (1992).
18. Janin, J. Elusive affinities. Proteins Struct. Funct. Genet. 21, 30-39 (1995).
19. Murphy, K.P., Xie, D., Thompson, K.S., Amzel, L.M. & Freire, E. Entropy in biological binding processes: Estimation of translational entropy loss. Proteins Struct. Funct. Genet. 18, 63-67 (1994).
20. Bussolati, L., Ramoni, R., Grolli, S., Donofrio, G. & Bignetti, E. Preparation of an affinity resin for odorant by coupling odorant binding protein from bovine nasal mucosa to Sepharose 4B. J. Biotech. 30, 225-230 (1993).
21. Napolitano, E. & Pelosi, P. Synthesis of thiazole and selenazole derivatives with affinity for the odorant-binding protein. Biorg. Medic. Chem. Letts. 2, 1603-1606 (1992).
22. Pevsner, J., Trifiletti, R.R., Strittmatter, S.M. & Snyder, S.H. Isolation and characterization of an olfactory receptor protein for odorant pyrazynes. Proc. Natl. Acad. Sci. USA 82, 3050-3054 (1985).
23. Sivaprasadarao, A. & Findlay, J.B.C. The interaction of retinol-binding protein with its plasma-membrane receptor. Biochem. J. 255, 561-569 (1988).
24. Bavik, C.O., Levy, F., Hellmann, U., Wernstedt, C. & Erkksson, U. The retinol pigment epithelial membrane receptor for plasma retinol-binding protein. J. Biol. Chem. 268, 20540-20546 (1993).
25. Boudjelal, M., Sivaprasadarao, A. & Findlay, J.B.C. Membrane receptor for odour-binding proteins. Biochem. J. 317, 23-27 (1996).
26. Zeng, C. et al. A human azillary odorant is carried by apolipoprotein D. Proc. Natl. Acad. Sci. 93, 6626-6630 (1996).
27. Reed, R.R. The molecular basis of sensitivity and specificity in olfaction. Sem. Cell Biol. 5, 33-38 (1994).
28. Kleywegt, G.J. & Jones, T.A. Detection, delineation, measurement and display of cavities in proteins. Acta Crystallogr. D50, 178-185 (1994).
29. Collaborative Computational Project Number 4. Acta Crystallogr. D50, 760-767 (1994).
30. Jones, T.A., Zou, J.Y., Cowan, S.W. & Kjelgaard, M. Improved methods for building protein models in electron density maps and location of errors in these maps. Acta Crystallogr. A47, 110-119 (1991).
31. Brünger, A.T. X-PLOR. A system for crystallography and NMR, 3.1 Manual. Yale Univ. Press, New Haven, CT (1992).
32. Nicholls, A., Sharp, K. & Honig, B. GRASP: Graphical representation and analysis of structural properties of proteins. Proteins 11, 281-296 (1991).
33. Tegoni, M., Ramoni, R., Bignetti, E., Spinelli, S. & Cambillau, C. Domain swapping creates a third putative combining site in bovine odorant binding protein dimer. Nature Struct. Biol. 3, 863-867 (1996).
34. Evans, S.V. SETOR: Hardware lighted three-dimensional solid model representations of macromolecules. J. Mol. Graphics 11, 134-138 (1993).