Methyl methanesulphonate (MMS) as a resource conserving and reliable positive control agent for male rat and male mouse dominant lethal assays

Mutagenesis

Volumn 11, Issue 6, 1996, Pages 611-613

  Ashby, J ^a   Lefevre, P A ^a   Elliott, B M ^a   Clapp, M J L ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MESYLIC ACID METHYL ESTER;

ANIMAL EXPERIMENT; ARTICLE; BREEDING; CONTROLLED STUDY; DOMINANT LETHAL TEST; EMBRYO; FEMALE; IMPLANTATION; MALE; MALE FERTILITY; MATING; MOUSE; MUTAGEN TESTING; MUTAGENIC ACTIVITY; NIDATION; NONHUMAN; PREGNANCY RATE; PRIORITY JOURNAL; RAT; SPERMATID; SPERMATOZOON;

ANIMALIA;

EID: 0029858241     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/11.6.611     Document Type: Article

References (7)

1. Adler, I.-D., Shelby, M.D., Bootman, J., Favor, J., Generoso, W., Pacchierotti, F., Shibuya, T. and Tanaka, N. (1994) Summary report of the working group on mammalian germ cell tests. Mutat. Res., 312, 313-318.
2. Ashby, J. and Clapp, M.J.L. (1995) The rodent dominant lethal assay: a proposed format for data presentation that alerts to psuedo-dominant lethal effects. Mutat. Res., 330, 209-218.
3. Ehling, U.H. and Neuhauser-Klaus, A. (1990) Induction of specific locus and dominant lethal mutations in male mice in the low dose range by MMS. Mutat. Res., 230, 61-70.
4. Ehling, U.H. and Neuhauser-Klaus, A. (1991) Induction of specific locus and dominant lethal mutations in male mice by MNU. Mutat. Res., 250, 447-456.
5. Gatehouse, D. (1994) Experience with use of the rat as the test species for bone marrow and peripheral blood micronucleus assays. MMS Comms., 2, 61-68.
6. Generoso, W.M. and Piegorsch, W.W. (1993) Dominant lethal tests in male and female mice. In Chapin, R.E. and Heindel, J.J. (eds). Male Reproductive Toxicology. Academic Press, San Diego, pp. 124-141.
7. Kratochvilova, J. (1978) Evaluation of pre-implantation loss in dominant-lethal assay in the mouse. Mutat. Res., 54, 47-54.