The role of circulating food antigen-specific lymphocytes in food allergic children with atopic dermatitis

British Journal of Dermatology

Volumn 135, Issue 6, 1996, Pages 935-941

  Reekers, R ^a   Beyer, K ^b   Niggemann, B ^b   Wahn, U ^b   Freihorst, J ^a   Kapp, A ^a   Werfel, T ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CD4 ANTIGEN; GAMMA INTERFERON;

ARTICLE; ATOPIC DERMATITIS; CELL CULTURE; CELL PROLIFERATION; CLINICAL ARTICLE; FOOD ALLERGY; HUMAN; IN VITRO STUDY; INFANT; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0029858154     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.1996.d01-1098.x     Document Type: Article

References (27)

1. Atherton DJ, Sewell M, Soothill JF et al. A double-blind controlled crossover trial of an antigen avoidance diet in atopic eczema. Lancet 1978; i: 401-3.
2. Sampson HA, McCaskill CC. Food hypersensitivity and atopic dermatitis: evaluation of 113 patients. J Pediatr 1985; 107: 669-75.
3. Sampson HA, Albergo R. Comparison of results of skin tests, RAST, and double blind, placebo-controlled food challenges in children with atopic dermatitis. J Allergy Clin Immunol 1984; 74: 26-33.
4. Abernathy-Carver KJ, Sampson HA, Picker LJ, Leung DYM. Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen. J Clin Invest 1995; 95: 913-18.
5. Atherton DJ, Bieber T, Bonifazi E et al. Severity scoring of atopic dermatitis: the SCORAD index. Dermatology 1993; 186: 23-31.
6. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venerol 1980; 92: 44-7.
7. Niggemann B, Wahn U, Sampson HA. Proposals for standardization of oral food challenge tests in infants and children. Pediatr Allergy Immunol 1994; 5: 11-13.
8. Karplus TE, Ulevitch RJ, Wilson CB. A new method for reduction of endotoxin contamination from protein solutions. J Immunol Methods 1987; 105: 211-20.
9. Sager N, Feldmann A, Schilling G et al. House dust mite specific T-cells in the skin of atopic dermatitis: frequency and lymphokine profile in the allergen patch test. Allergy Clin Immunol 1992; 89: 801-10.
10. Taswell C. Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. J Immunol 1981; 126: 1614-40.
11. Strijbosch LWG, Does RJM, Buurman WA. Computer aided design and evaluation of limiting and serial dilution experiments. Int J Biomed Comput 1988; 23: 279-90.
12. Prausnitz C, Küstner H. Studies on supersensitivity. Zentralbl Bakteriol Parasitenkd Infektionskr Hyg Abt 1921; 86: 160-9.
13. Walzer M. Studies in absorption of undigested proteins in human beings. I. A simple direct method of studying the absorption of undigested protein. J Immunol 1927; 14: 143-74.
14. Burks AW, Mallory SB, Williams, LW, Shirrell MA. Atopic dermatitis: clinical relevance of food hypersensitivity reactions. J Pediatr 1988; 113: 447-51.
15. Sampson HA, Mendelson L, Rosen JP. Fatal and near-fatal anaphylactic reactions to food in children and adolescents. N Engl J Med 1992; 327: 380-4.
16. Burks AW, Sampson HA. Diagnostic approaches to the patients with suspected food allergies. J Pediatr 1992; 121: 64-71.
17. Sampson HA. Immunologically mediated food allergy: the importance of food challenge procedures. Ann Allergy 1988; 60: 262-9.
18. Hill DJ, Firer MA, Shelton MJ, Hoskings CS. Manifestations of milk allergy in infancy: clinical and immunologic findings. J Pediatr 1986; 109: 270-6.
19. Kapp A, Czech W, Krutmann J, Schöpf E. Eosinophil cationic protein in sera of patients with atopic dermatitis. J Am Acad Dermatol 1991; 24: 555-8.
20. Niggemann B, Beyer K, Wahn U. The role of eosinophils and eosinophil cationic protein in monitoring oral challenge tests in children with food-sensitive atopic dermatitis. J Allergy Clin Immunol 1994; 94: 963-71.
21. Werfel T, Ahlers G, Schmidt P et al. Milk-responsive atopic dermatitis is associated with a casein-specific lymphocyte response in adolescent and adult patients. J Allergy Clin Immunol (in press).
22. Räsänen L, Lehto M, Reunala T. Diagnostic value of skin and laboratory tests in cow's milk allergy/intolerance. Clin Exp Allergy 1992; 22: 385-90.
23. Kondo N, Agata H, Fukutomi O et al. Lymphocyte response to food antigens in patients with atopic dermatitis who are sensitive to foods. J Allergy Clin Immunol 1990; 86: 253-60.
24. Erard F, Wild MT, Garcia Sanz JA, Le Gros G. Switch of CD8 T cells to noncytolytic CD8- CD4- cells that make TH2 cytokines and help B cells. Science 1993; 260: 1802-5.
25. Seder RA, Boulay JL, Finkelmann F et al. CD8+ cells can be primed in vitro to produce IL-4. J Immunol 1992; 148: 1652-6.
26. Manetti R, Annunziato F, Biagiotti R et al. CD30 expression by CD8+ T cells producing type 2 helper cytokines. Evidence for large numbers of CD8+CD30+ T cell clones in human immunodeficiency virus infection. J Exp Med 1994; 180: 2407-11.
27. Manetti R, Parronchi P, Giudizi MS et al. Natural killer cell stimulatory factor (interleukin-12) induces T helper type I (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J Exp Med 1993; 177: 1199-204.