Induction of humoral and cellular anti-idiotypic immunity by intradermal injection of naked DNA encoding a human variable region gene sequence of an immunoglobulin heavy chain in a B cell malignancy

Gene Therapy

Volumn 3, Issue 11, 1996, Pages 988-993

  Abe, A ^a   Emi, N ^a,c   Taji, H ^b   Kasai, M ^a   Kohno, A ^a   Saito, H ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JAPANESE RED CROSS NAGOYA FIRST HOSPITAL   (Japan)

^c First Dept of Internal Medicine   (Japan)

Author keywords

B cell malignancy; CTL; Idiotype; Immunity

Indexed keywords

IDIOTYPIC ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B CELL LEUKEMIA; CELLULAR IMMUNITY; DNA TRANSFER; GENE THERAPY; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; INTRACUTANEOUS TEST; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODY FORMATION; B-LYMPHOCYTES; BASE SEQUENCE; DNA; HUMANS; IMMUNITY, CELLULAR; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; INJECTIONS, INTRADERMAL; LEUKEMIA, B-CELL, ACUTE; MICE; MICE, INBRED DBA; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTES, CYTOTOXIC;

ANIMALIA; BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 0029857782     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Wolff JA et al. Direct gene transfer into mouse muscle in vivo Science 1990; 247: 1465-1468.
2. Tang D, Devit M, Johnston SA. Genetic immunization is a simple method for eliciting an immune response. Nature 1992; 356: 152-154.
3. Katsumi A et al. Humoral and cellular immunity to an encoded protein induced by direct DNA injection. Hum Gene Ther 1994; 5: 1335-1339.
4. Spooner RA, Deonarain MP, Epenetos AA. DNA vaccination for cancer treatment. Gene Therapy 1995, 2: 173-180.
5. Restifo NF et al. Antigen processing in vivo and the elicitation of primary CTL responses. J Immunol 1995; 154: 4414-4422.
6. Stevenson GT, Stevenson GK. Antibody to molecularly defined antigen confined to a tumor cell surface. Nature 1975; 254: 714-716.
7. Stewart AK, Schwartz RS. Immunoglobulin V regions and the B cell. Blood 1994; 83: 1717-1730.
8. George AJ et al. Idiotypic vaccination as a treatment for a B cell lymphoma. J Immunol 1988; 141: 2168-2174.
9. Dyke RJ et al. Idiotypic vaccination against B cell lymphoma lead to dormant tumour. Cell Immunol 1991; 132: 70-83.
10. Meeker TC et al. A clinical trial of anti-idiotype therapy for B cell malignancy. Blood 1985; 65: 1349-1363.
11. Kiyoi K et al. Characterization of the immunoglobulin heavy chain complementarity determining region (CDR)-III sequence from human B cell precursor acute lymphoblastic leukemia cells. J Clin Invest 1992; 89: 739-746.
12. Kwak LW et al. Induction of immune responses in patients with B cell lymphoma against the surface-immunoglobulin idiotype expressed by their rumors. New Engl J Med 1992; 327. 1209-1215.
13. Hawkins RE et al. A genetic approach to idiotypic vaccination. J Immunother 1993; 14: 273-278.
14. Hawkins RE et al. Idiotypic vaccination against human B cell lymphoma. Rescue of variable region gene sequences from biopsy material for assembly as single-chain Fv personal vaccines. Blood 1994; 83: 3279-3288.
15. Raz E et al. Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses. Proc Natl Acad Sci USA 1994; 91: 9519-9523.
16. Campbell MJ et al. Idiotype vaccination against murine B cell lymphoma. Humoral and cellular requirements for the full expression of antitumor immunity. J Immunol 1990; 145: 1029-1036.
17. van Endert PM et al. Monoclonal antibodies to idiotype inhibit in vitro growth of human B cell lymphomas. Blood 1992; 79: 129-137
18. Kwak LW et al. Transfer of myeloma idiotype-specific immunity from an actively immunized marrow donor. Lancet 1995; 345: 1016-1020.
19. Tao MH, Levy R. Idiotype/granulocyte-macrophage colony-stimulating factor fusion protein as a vaccine for B cell lymphoma. Nature 1993; 362: 755-758.
20. van der Bruggen P et al. A gene encoding an antigen recognized by cytolytic T lymphocytes in a human melanoma. Science 1991; 254: 1643-1648.
21. Kawakami Y et al. Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes. J Exp Med 1994; 180: 347-352.
22. Hsu FJ et al. Vaccination of patients with B cell lymphoma using autologous antigen-pulsed dendritic cells. Nature Med 1996; 2: 52-58.
23. Chirgwin JM et al. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979; 18: 5294-5299.
24. Campbell MJ et al. Use of family specific reader region primers for PCR amplification of the human heavy chain variable region gene repertoire. Mol Immunol 1992; 29: 193-203.
25. Emi N, Friedmann T, Yee JK. Pseudotype formation of murine leukemia virus with the G protein of vesicular stomatitis virus J Virol 1991; 65: 1202-1207.
26. Van PA, De PE, Boon T. Selection of highly transfectable variant from mouse mastocytoma P815. Somat Cell Mol Genet 1985; 11. 467-175.
27. Abe A et al. Transduction of a drug-sensitive toxic gene into human leukemia cell lines with a novel retroviral vector. Proc Soc Exp Biol Med 1993; 203: 354-359.
28. Isobe K et al. Induction of antitumor immunity in mice by allomajor histocompatibility complex class I gene transfectant with strong antigen expression. J Natl Cancer Inst 1989; 81: 1823-1828.