Microencapsulation for cell implants into the central nervous system: The importance of alginate viscosity and related factors

Stereotactic and Functional Neurosurgery

Volumn 66, Issue 1-3, 1996, Pages 141-146

  Chen, Zhong Ping ^a   Mohr, Gérard ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Alginate; Autocave time; Cell transplantation; Microencapsulation

Indexed keywords

ALGINIC ACID; POLYLYSINE;

AUTOCLAVE; CELL TRANSPLANTATION; CENTRAL NERVOUS SYSTEM; CONFERENCE PAPER; MEMBRANE PERMEABILITY; MICROENCAPSULATION; VISCOSITY;

ALGINATES; BIOCOMPATIBLE MATERIALS; CAPSULES; CELL TRANSPLANTATION; CENTRAL NERVOUS SYSTEM; GLUCURONIC ACID; HEAT; HEXURONIC ACIDS; HUMANS; STERILIZATION; TIME FACTORS; VISCOSITY;

EID: 0029857610     PISSN: 10116125     EISSN: None     Source Type: Journal    
DOI: 10.1159/000099681     Document Type: Conference Paper

References (13)

1. Lim F, Sun AM: Microencapsulated islets as bioartificial endocrine pancreas. Science 1980;210:908-910.
2. Scharp DW, Mason NS, Spark RE: Immuno-isolation: The use of hybrid artificial organs to prevent islet tissue rejection. World J Surg 1984;8:221-229.
3. Goosen MFA, O'shea GM, Gharapetian HM, Chou S, Sun AM: Optimization of microencapsulation parameters: Semipermeable microcapsules as a bioartificial pancreas. Biotechnol Bioengin 1985;27:146-150.
4. Mikos AG, Papadaki MG, Konvroukoglon S, Ishang SL, Thomson RC: Mini-review: Islet transplantation to create a bioartificial pancreas. Biotechnol Bioengin 1994;43:673-677.
5. Matthew HW, Salley SO, Peterson WD, Klein MD: Complex coacervate microcapsules for mammalian cell culture and artificial organ development. Biotechnol Prog 1993;9:510-519.
6. Menei P, Benoit JP, Boisdron-Celle M, Fournier D, Mercier P, Guy G: Drug targeting into the central nervous system by stereotactic microspheres. Neurosurgery 1994;34:1058-1064.
7. Aebischer P, Buchser E, Favre J, Goddard M, de Tribolet N: Transplantation of encapsulated bovine chromaffin cells in terminal cancer patients with intractable pain (abstract). 62nd Annual Meeting of the American Association of Neurological Surgeons. San Diego, April 9-14, 1994. p 192.
8. Winn SR, Tresco PA, Zielinski B, Greene LA, Jaeger CB, Aebischer P: Behavioral recovery following intrastriatal implantation of microencapsulated PC 12 cells. Exp Neurol 1991;113: 322-329.
9. Christenson L, Emerich DF, Sanberg PR: Encapsulated cell implantation for Parkinson's disease. Mov Disord 1992;7:185-186.
10. Maysinger D, Piccardo P, Liberini P, Jaisenjak I, Cuello AC: Encapsulated genetically engineered fibroblasts: Release of nerve growth factor and effects in vivo on recovery of cholinergic markers after devascularizing cortical lesions. Neurochem Int 1994;24:495-503.
11. Chen ZP, Bao YD: Study of microencapsulated pituitary transplantation: Preparation of the capsule and its property. Chin Med J 1994;107:200-204.
12. Chen ZP, Gorczyca W, Mohr G: Study of microencapsulation for pituitary transplantation: Capsule preparation and in vitro study Artif Cells Blood Substit Immobil Biotechnol 1994;22:A8.
13. Lloyd-George I, Chang TMS: Effects of process variables on the relative strength and size distribution of alginate-poly-lysine-alginate microcapsules. Artif Cells Blood Substit Immobil Biotechnol 1994;22.A31.