EI-1511-3, -5 and EI-1625-2, novel interleukin-1β converting enzyme inhibitors produced by Streptomyces sp. E-1511 and E-1625. II. Structure determination

Journal of Antibiotics

Volumn 49, Issue 11, 1996, Pages 1079-1084

  Uosaki, Youichi ^a   Agatsuma, Tsutomu ^a   Tanaka, Takeo ^a   Saitoh, Yutaka ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EI 1511 3; EI 1511 5; EI 1625 2; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG STRUCTURE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0029857598     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.49.1079     Document Type: Article

References (12)

1. TANAKA, T.; E. TSUKUDA, K. OCHIAI, H. KONDO, S. TESHIBA & Y. MATSUDA: EI-1511-3, -5 and EI-1625-2, novel interleukin-1β converting enzyme inhibitors pro- duced by Streptomyces sp. E-1511 and E-1625. I. Taxonomy of producing strain, fermentation and isolation. J. Antibiotics 49: 1073-1078, 1996
2. ZEEK, A.; K. SCHRÖDER, K. FROBEL, R. GROTE & R. THIERICKE: The structure of manumycin. I. Characterization, structure elucidation and biological activity. J. Antibiotics 40: 1530-1540, 1987
3. SATTLER, I.; C. GRÖNE & A. ZEECK: New compounds of the manumycin group, of antibiotics and a facilitated route for their structure elucidation. J. Org. Chem. 58: 6583-6587, 1993
4. SHU, Y.-Z.; S. HUANG, R. R. WANG, K. S. LAM, S. E. KLOHR, K. J. VOLK, D. M. PIRNIK, J. S. WELLS, P. B. FERNANDES & P. S. PATEL: Manumycins E, F and G, new members of manumycin class antibiotics from Streptomyces sp. J. Antibiotics 47: 324-333, 1994
5. BRODASKY, T. F.; D. W. STROMAN, A. DIETZ & S. MIZSAK: U-56,407, new antibiotic related to asukamycin: Isolation and characterization. J. Antibiotics 36: 950-956, 1983
6. CHATTERJEE, S.; E. K. S. VIJAYAKUMAR, C. M. M. FRANCO, J. BLUMBACH, B. N. GANGULI, H.-W. FEHLHABER & H. KOGLER: On the structure of alisamycin, a new member of the manumycin class of antibiotics. J. Antibiotics 46: 1027-1030, 1993
7. CHO, H.; I. SATTLER, J. M. BEALE, A. ZEECK & H. G. FLOSS: Some aspects of the stereochemistry and biosynthesis of asukamycin. J. Org. Chem 58: 7925-7928, 1993
8. HARADA, N. & K. NAKANISHI (Ed.): Circular dichroic spectroscopy, exciton coupling in organic stereochemistry. Oxford University Press, Oxford, 1983
9. THIERICKE, R.; M. STELLWAAG, A. ZEECK & G. SNATZKE: The structure of manumycin. III. Absolute configuration and conformational studies. J. Antibiotics 40: 1549-1554, 1987
10. TANAKA, T.; E. TSUKUDA, Y. UOSAKI & Y. MATSUDA: EI-1511-3, -5 and EI-1625-2, novel interleukin-1β converting enzyme inhibitors produced by Streptomyces sp. E-1511 and E-1625. III. Biochemical properties of EI-1511-3, -5 and EI-1625-2. J. Antibiotics 49: 1085-1090, 1996
11. HARA, M.; K. AKASAKA, S. AKINAGA, M. OKABE, H. NAKANO, R. GOMEZ, D. WOOD, M. UH & F. TAMANOI: Identification of Ras farnesyltransferase inhibitors by microbial screening. Proc. Nat. Acad. Sci. USA 90: 2281-2285, 1993
12. KAKINUMA, K.; N. IKEKAWA, A. NAKAGAWA & S. OMURA: The structure of asukamycin, a possible shunt metabolite from 3-dehydroquinic acid in the shikimate pathway. J. Amer. Chem. Soc. 101: 3402-3404, 1979