-
1
-
-
0019642619
-
Midazolam kinetics
-
Allonen, H., Ziegler, G., Klotz, U. (1981) Midazolam kinetics. Clin. Pharmacol. Ther. 30: 653-661
-
(1981)
Clin. Pharmacol. Ther.
, vol.30
, pp. 653-661
-
-
Allonen, H.1
Ziegler, G.2
Klotz, U.3
-
2
-
-
0022998708
-
Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism
-
Guengerich, F. P., Martin, M. V., Beaune, P. H., Kremers, P., Wolff, T., Waxman, D. J. (1986) Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism. J. Biol. Chem. 261: 5051-5060
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 5051-5060
-
-
Guengerich, F.P.1
Martin, M.V.2
Beaune, P.H.3
Kremers, P.4
Wolff, T.5
Waxman, D.J.6
-
3
-
-
0026601064
-
Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol
-
Hunt, C. M., Watkins, P. B., Saenger, P., Stave, G. M., Barlascini, N., Watlington, C. O., Wrighl, J. T., Guzelian, P. S. (1992) Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol. Clin. Pharmacol. Ther. 51: 18-23
-
(1992)
Clin. Pharmacol. Ther.
, vol.51
, pp. 18-23
-
-
Hunt, C.M.1
Watkins, P.B.2
Saenger, P.3
Stave, G.M.4
Barlascini, N.5
Watlington, C.O.6
Wrighl, J.T.7
Guzelian, P.S.8
-
4
-
-
0027770062
-
Absence of correlations among three putative in-vivo probes of human cytochrome P450 3A activity in young healthy men
-
Kinirons, M. T., O'Shea, D., Downing, T. E., Fitzwilliam, A. T., Joellenbeck, L., Groopman, J. D., Wilkinson, G. R., Wood, A. J. J. (1993) Absence of correlations among three putative in-vivo probes of human cytochrome P450 3A activity in young healthy men. Clin. Pharmacol. Ther 54: 621-629
-
(1993)
Clin. Pharmacol. Ther
, vol.54
, pp. 621-629
-
-
Kinirons, M.T.1
O'Shea, D.2
Downing, T.E.3
Fitzwilliam, A.T.4
Joellenbeck, L.5
Groopman, J.D.6
Wilkinson, G.R.7
Wood, A.J.J.8
-
5
-
-
0028608020
-
Metabolism of cytochrome P450 3A substrates in vivo administered by the same route: Lack of correlation between alfentanil clearance and erythromycin breath test
-
Krivoruk, Y., Kinirons, M. T., Wood, A. J. J., Wood, M. (1994) Metabolism of cytochrome P450 3A substrates in vivo administered by the same route: lack of correlation between alfentanil clearance and erythromycin breath test. Clin. Pharmacol. Ther. 56: 608-614
-
(1994)
Clin. Pharmacol. Ther.
, vol.56
, pp. 608-614
-
-
Krivoruk, Y.1
Kinirons, M.T.2
Wood, A.J.J.3
Wood, M.4
-
6
-
-
0028113492
-
Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test
-
Lown, K. S., Kolars, J. C., Thummel, K. E., Barnett, J. L., Kunze, K. L., Wrighton, S. A., Watkins, P. B. (1994) Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test. Drug Metab. Dispos. 22: 947-955
-
(1994)
Drug Metab. Dispos.
, vol.22
, pp. 947-955
-
-
Lown, K.S.1
Kolars, J.C.2
Thummel, K.E.3
Barnett, J.L.4
Kunze, K.L.5
Wrighton, S.A.6
Watkins, P.B.7
-
7
-
-
0026787506
-
The influence of posture on the pharmacokinetics of orally administered nifedipine
-
Renwick, A. G., Ahsan, C. H., Challenor, V. F., Daniels, R., Macklin, B. S., Waller, D. G., George, C. F. (1992) The influence of posture on the pharmacokinetics of orally administered nifedipine. Br. J. Clin. Pharmacol. 34: 332-336
-
(1992)
Br. J. Clin. Pharmacol.
, vol.34
, pp. 332-336
-
-
Renwick, A.G.1
Ahsan, C.H.2
Challenor, V.F.3
Daniels, R.4
Macklin, B.S.5
Waller, D.G.6
George, C.F.7
-
9
-
-
0023943652
-
Lack of bimodality in nifedipine kinetics in a large population of healthy subjects
-
Schellens, J. H. M., Soons, P. A., Breiner, D. D. (1988) Lack of bimodality in nifedipine kinetics in a large population of healthy subjects. Biochem. Pharmacol. 37: 2507-2510
-
(1988)
Biochem. Pharmacol.
, vol.37
, pp. 2507-2510
-
-
Schellens, J.H.M.1
Soons, P.A.2
Breiner, D.D.3
-
10
-
-
0023853892
-
Determination of nifedipine and its three principal metabolites in plasma and urine by automated electron-capture capillary gas chromatography
-
Schmid, B. J., Perry, H. E., Idle, J. R. (1988) Determination of nifedipine and its three principal metabolites in plasma and urine by automated electron-capture capillary gas chromatography. J. Chromatogr. 425: 107-119
-
(1988)
J. Chromatogr.
, vol.425
, pp. 107-119
-
-
Schmid, B.J.1
Perry, H.E.2
Idle, J.R.3
-
11
-
-
0028114619
-
Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients
-
Thummel, D. E., Shen, D. D., Podoll, T. D., Kunze, K. L., Trager, W. F., Hartwell, P. S., Raisys, V. A., Marsh, C. L., McVicar, J. P., Barr, D. M., Perkins, J. D., Carithers, R. L. (1994a) Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients. J. Pharmacol. Exp. Ther. 271: 549-556
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.271
, pp. 549-556
-
-
Thummel, D.E.1
Shen, D.D.2
Podoll, T.D.3
Kunze, K.L.4
Trager, W.F.5
Hartwell, P.S.6
Raisys, V.A.7
Marsh, C.L.8
McVicar, J.P.9
Barr, D.M.10
Perkins, J.D.11
Carithers, R.L.12
-
12
-
-
0027985506
-
Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation
-
Thummel, K. E., Shen, D. D., Podoll, T. D., Kunze, K. L., Trager, W. F., Bacchi, C. E., Marsh, C. L., McVicar, J. P., Barr, D. M., Perkins, J. B., Carithers, R. L. (1994b) Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation. J. Pharmacol. Ther. 271: 557-566
-
(1994)
J. Pharmacol. Ther.
, vol.271
, pp. 557-566
-
-
Thummel, K.E.1
Shen, D.D.2
Podoll, T.D.3
Kunze, K.L.4
Trager, W.F.5
Bacchi, C.E.6
Marsh, C.L.7
McVicar, J.P.8
Barr, D.M.9
Perkins, J.B.10
Carithers, R.L.11
-
13
-
-
0028149595
-
P450 3A activity and cyclosporin dosing in kidney and heart transplant recipients
-
Turgeon, D. K., Leichtman, A. B., Lown, K. S., Normolle, D. P., Deeb, G. M., Merion, R. M., Watkins, P. B. (1994a) P450 3A activity and cyclosporin dosing in kidney and heart transplant recipients. Clin. Pharmacol. Ther. 56: 253-260
-
(1994)
Clin. Pharmacol. Ther.
, vol.56
, pp. 253-260
-
-
Turgeon, D.K.1
Leichtman, A.B.2
Lown, K.S.3
Normolle, D.P.4
Deeb, G.M.5
Merion, R.M.6
Watkins, P.B.7
-
14
-
-
0028277839
-
Prediction of interpatient and intrapatient variation in OG 37-325 dosing requirements by the erythromycin breath test: A prospective study in renal transplant recipients
-
Turgeon, D. K., Leichtman, A. B., Blake, D. S., Schmouder, R. L., Lown, K. S., Annesley, T. M., Watkins, P. B. (1994b) Prediction of interpatient and intrapatient variation in OG 37-325 dosing requirements by the erythromycin breath test: a prospective study in renal transplant recipients. Transplantation 57: 1736-1741
-
(1994)
Transplantation
, vol.57
, pp. 1736-1741
-
-
Turgeon, D.K.1
Leichtman, A.B.2
Blake, D.S.3
Schmouder, R.L.4
Lown, K.S.5
Annesley, T.M.6
Watkins, P.B.7
-
15
-
-
0028568243
-
Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole
-
Varhe, A., Olkkola, K. T., Neuvonen, P. J. (1994) Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole. Clin. Pharmacol. Ther. 56: 601-607
-
(1994)
Clin. Pharmacol. Ther.
, vol.56
, pp. 601-607
-
-
Varhe, A.1
Olkkola, K.T.2
Neuvonen, P.J.3
-
16
-
-
0028071759
-
Noninvasive tests of CYP3A enzymes
-
Watkins, P. B. (1994) Noninvasive tests of CYP3A enzymes. Pharmacogenetics 4: 171-184
-
(1994)
Pharmacogenetics
, vol.4
, pp. 171-184
-
-
Watkins, P.B.1
-
17
-
-
0025063782
-
The erythromycin breath test as a predictor of cyclosporin blood levels
-
Watkins, P. B., Hamilton, T. A., Annesley, T. M., Ellis, C. N., Kolars, J. C., Voorhees, J. J. (1990) The erythromycin breath test as a predictor of cyclosporin blood levels. Clin. Pharmacol. Ther. 48: 120-129
-
(1990)
Clin. Pharmacol. Ther.
, vol.48
, pp. 120-129
-
-
Watkins, P.B.1
Hamilton, T.A.2
Annesley, T.M.3
Ellis, C.N.4
Kolars, J.C.5
Voorhees, J.J.6
-
18
-
-
0026732029
-
Comparison of urinary 6-β-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity
-
Watkins, P. B., Turgeon, D. K., Saenger, P., Lown, K. S., Kolars, J. C., Hamilton, T., Fishman, K., Guzelian, P. S., Voorhees, J. J. (1992) Comparison of urinary 6-β-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity. Clin. Pharmacol. Ther. 52: 265-273
-
(1992)
Clin. Pharmacol. Ther.
, vol.52
, pp. 265-273
-
-
Watkins, P.B.1
Turgeon, D.K.2
Saenger, P.3
Lown, K.S.4
Kolars, J.C.5
Hamilton, T.6
Fishman, K.7
Guzelian, P.S.8
Voorhees, J.J.9
-
19
-
-
0026750647
-
The human hepatic cytochromes P450 involved in drug metabolism
-
Wrighton, S. A., Stevens, J. C. (1992) The human hepatic cytochromes P450 involved in drug metabolism. Crit. Rev. in Toxicol. 22: 1-21
-
(1992)
Crit. Rev. in Toxicol.
, vol.22
, pp. 1-21
-
-
Wrighton, S.A.1
Stevens, J.C.2
|