Monoclonal gammopathy and neuropathy

Current Opinion in Neurology

Volumn 9, Issue 5, 1996, Pages 334-337

  Notermans, Nicolette C ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CHLORAMBUCIL; CYCLOPHOSPHAMIDE; GLYCOCONJUGATE; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; PREDNISONE;

ANTIBODY TITER; ANTIGEN BINDING; B LYMPHOCYTE; CLINICAL TRIAL; DEMYELINATION; DISEASE ASSOCIATION; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LYMPHOCYTE CLONE; MONOCLONAL IMMUNOGLOBULINEMIA; MYELIN SHEATH; ORAL DRUG ADMINISTRATION; PERIPHERAL NERVOUS SYSTEM; PLASMAPHERESIS; POLYNEUROPATHY; SHORT SURVEY;

EID: 0029856480     PISSN: 13507540     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019052-199610000-00003     Document Type: Short Survey

References (20)

1. Latov N: Pathogenesis and therapy of neuropathies associated with monoclonal gammopathies. Ann Neurol 1995, 37(Suppl1):S32-S42. This author gives a clear and complete review of the neuropathic syndromes that are associated with monoclonal gammopathies, and discusses the evaluation and treatment of patients who present with serum M proteins and neuropathy. Special attention is given to the pathogenic relevance of autoantibodies.
2. Notermans NC, Wokke JHJ, Lokhorst HM, Franssen H, van der Graaf Y, Jennekens FGI: Polyneuropathy associated with monoclonal gammopathy of undetermined significance. A prospective study of the prognostic value of clinical and laboratory abnormalities. Brain 1994, 117:1385-1393.
3. Nobile-Orazio E, Manfredini E, Carpo M, Meucci N, Monaco S, Ferari S, Bonnetti B, Cavaletti G, Gemignani F, Durelli L et al.: Frequency and clinical correlates of anti-neural IgM antibodies in neuropathy associated with IgM monoclonal gammopathy. Ann Neurol 1994, 36:416-424.
4. Vrethem M, Ekerfelt C, Ernerudh J: Avidity distribution of antibodies against peripheral nerve myelln In patients with polyneuropathy associated with IgM monoclonal gammopathy and in healthy controls. J Neurol Sci 1995, 131:190-199.
5. Ellie E, Vital A, Steck A, Boiron JM, Vital C, Julien J: Neuropathy associated with 'benign' anti-myelin associated glycoprotein IgM gammopathy: clinical, immunological, neurophyslological pathological findings and response to treatment in 33 cases. J Neurol 1996, 243:34-43.
6. Tatum AH: Experimental paraprotein neuropathy, demyelination by passive transfer of human IgM anti-myelin-associated-glycoprotein. Ann Neurol 1993, 33:502-506.
7. Monaco S, Ferrari S, Bonetti B, Moretto G, Kirshfink M, Nardelli E, Nobile-Orazio E, Zanusso G, Rizzuto N, Tedesco F: Experimental Induction of myelin changes by anti-MAG antibodies and terminal latency complement complex. J Neuropathol Exp Neurol 1995, 54:96-104.
8. Oksenhendler E, Chrevet S, Léger J-M, Louboutin J-P, Bussel A, Brouet J-C for the IgM-associated Polyneuropathy Study Group: Plasma exchange and chlorambucil in polyneuropathy associated with monoclonal IgM gammopathy. J Neurol Neurosurg Psychiatry 1995, 59:243-247. In a double-blind, placebo-controlled prospective study, the authors compared chlorambucil treatment, in combination with and without plasmapheresis, in patients with polyneuropathy associated with IgM M-protein. The results showed that plasmapheresis confers no additional benefit.
9. Suarez GA, Kelly JJ: Polyneuropathy associated with monoclonal gammopathy of undetermined significance. Further evidence that IgM-MGUS neuropathies are different than IgG-MGUS. Neurology 1993, 43: 1304-1308.
10. Smith IS: The natural history of chronic demyelinating neuropathy associated with benign IgM paraproteinaemia. A clinical and neurophysiological study. Brain 1994, 117:949-957.
11. Trojaborg W, Hays AP, Van den Berg LH, Younger DS, Latov N: Motor conduction parameters In neuropathies associated with anti-MAG antibodies and other types of demyelinating and axonal neuropathies. Muscle Nerve 1995, 18:730-735. Motor nerve conduction studies in patients with neuropathies associated with anti-MAG or sulfoglucuronylparagloboside antibodies were compared with values obtained in 103 patients with other types of polyneuropathy and with 57 normal individuals.
12. Van den Berg LH, Lankamp CLAM, De Jager AEJ, Notermans NC, Sodaar P, Marrink J, de Jong HJ, Bär PR, Wokke JHJ: Anti-sulphatide antibodies in peripheral neuropathy. J Neurol Neurosurg Psychiatry 1993, 56:1164-1168.
13. McAlarney T, Pastores GM, Hays AP, Latov N: Antisulfatide antibody and neuropathy in a patient with Gaucher's disease. Neurology 1995, 45:1622-1623.
14. Bouche P, Moulonguet A, Ben Younes-Chennoufi A, Adams D, Baumann N, Meininger V, Léger J-M, Said G: Multifocal motor neuropathy with conduction block. A study of 24 patients. J Neurol Neurosurg Psychiatry 1995, 59:38-44.
15. Van den Berg LH, Franssen H, Wokke JHJ: Improvement of multifocal motor neuropathy during long-term weekly treatment with human immunoglobulin. Neurology 1995, 45:987-988.
16. Notermans NC, Wokke JHJ, Van der Graaf Y, Franssen H, van Dijk GW, Jennekens FGI: Chronic idiopathic axonal polyneuropathy: a 5 year follow-up. J Neurol Neurosurg Psychiatry 1994, 57:1525-1527.
17. Notermans NC, Wokke JHJ, Van den Berg LH, Van der Graaf Y, Fransssen H, Teunissen LL, Lokhorst HM: Chronic idiopathic axonal polyneuropathy: comparison of patients with and without monoclonal gammopathy. Brain 1996, 119:421-428. The clinical, electrophysiological and pathological features of 16 patients with chronic idiopathic axonal polyneuropathy with monoclonal gammopathy of undetermined significance were compared with 71 patients who had chronic idiopathic axonal polyneuropathy without monoclonal gammopathy of undetermined significance.
18. Simmons Z, Albers JW, Bromberg MB, Feldman EL: Long-term follow-up of patients with chronic inflammatory demyelinating polyradiculopathy, without and with monoclonal gammopathy. Brain 1995, 118:359-368. The authors compared the clinical course of patients with CIDP with and without M-protein. They found several differences between the groups.
19. Notermans NC, Lokhorst HM, Franssen H, Teunissen LL, Jennekens FGI: Intermittent cyclophosphamide and prednisone treatment of polyneuropathy associated with monoclonal gammopathy of undetermined significance [Abstract]. Neurology 1996, 46:S235.
20. Blume G, Pestronk A, Goodnough LT: Anti-MAG antibody-associated polyneuropathies: improvement following immunotherapy with monthly plasma exchange and IV cyclophosphamide. Neurology 1995. 45: 1577-1580.