A synthesis of (2R,4'R,8'R)-α-tocopherol (vitamin E) side chain

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 11, 1996, Pages 2153-2156

  Chen, Cheng Yu ^a   Nagumo, Shinji ^a,b   Akita, Hiroyuki ^a  

^a TOHO UNIVERSITY   (Japan)

^b HOKKAIDO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

(3R,7R) 3,7,11 trimethyldodecan 1 ol; chiral isoprene unit; sulfone; tocopherol

Indexed keywords

ALPHA TOCOPHEROL;

ACETYLATION; ANTIOXIDANT ACTIVITY; ARTICLE; DRUG PURITY; DRUG SYNTHESIS; ISOMERISM;

EID: 0029856447     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.2153     Document Type: Article

References (4)

1. Recent asymmetric synthesis of α-tocopherol side chain; Fujiwara J., Fukutani Y., Hasegawa M., Maruoka K., Yamamoto H., J. Am. Chem. Soc., 106, 5004-5005 (1984) and references cited therein.
2. a) Akita H., Chen Cheng Yu, Nagumo S., Tetrahedron: Asymmetry, 5, 1207-1210 (1994);
3. b) Idem, J. Chem. Soc., Perkin Trans. I, 1995, 2159-2164.
4. Plesek J., Collect. Czech. Chem. Commun., 22, 644-647 (1957).