Non-suppressible parathyroid hormone secretion is related to gland size in uremic secondary hyperparathyroidism

Kidney International

Volumn 50, Issue 5, 1996, Pages 1663-1671

  Indridason, Olafur S ^b   Heath III, Hunter ^b   Khosla, Sundeep ^b   Yohay, Daniel A ^b   Quarles, L Darryl ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

PARATHYROID HORMONE;

ARTICLE; CALCIUM METABOLISM; CONTROLLED STUDY; HUMAN; HYPERCALCEMIA; MAJOR CLINICAL STUDY; ORGAN SIZE; PRIMARY HYPERPARATHYROIDISM; PRIORITY JOURNAL; SECONDARY HYPERPARATHYROIDISM; UREMIA;

EID: 0029856259     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1996.483     Document Type: Article

References (43)

1. FELSENFELD AJ, LLACH F: Parathyroid gland function in chronic renal failure. Kidney Int 43:771-789, 1993
2. GALBRAITH SC, QUARLES LD: Tertiary hyperparathyroidism and refractory secondary hyperparathyroidism, in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, edited by FAVUS MJ, New York, Raven Press, 1993, p 159
3. DROWN EM, WILSON RE, EASTMAN RC, PALLOTTA J, MARYNICK SP: Abnormal regulation of parathyroid hormone release by calcium in secondary hyperparathyroidism due to chronic renal failure. J Clin Endocrinol Metabol 54:172-179, 1982
4. WALLFELT C, GYLFE E, LARSSON R, LJUNGHALL S, RASTAD J, AKERSTROM G: Relationship between external and cytoplasmic calcium concentrations, parathyroid hormone release and weight of parathyroid glands in human hyperparathyroidism. J Endocrinol 116: 457-464, 1988
5. MALBERTI F, CORRADI B, PAGLIARI B, ROMANINI D, GAZO A, SIDOTI A, BARETTA A, BELLAZZI R, IMBASCIATI E: The sigmoidal parathyroid hormone-ionized calcium curve and the set point of calcium in hemodialysis and continuous ambulatory peritoneal dialysis. Perit Dial Int 13:S476-S479, 1993
6. FELSENFELD AJ, RODRIGUEZ M, DUNLAY R, LLACH F: A comparison of parathyroid-gland function in haemodialysis patients with different forms of renal osteodystrophy. Nephrol Dial Transplant 6:244-251, 1991
7. MCCARRON DA, MUTHER RS, LENFESTY B, BENNETT WM: Parathyroid function in persistent hyperparathyroidism: Relationship to gland size. Kidney International 22:662-670, 1982
8. RAMIREZ JA, GOODMAN WG, GORNBEIN J, MENEZES C, MOULTON L, SEGRE GV, SALUSKY IB: Direct in vitro comparison of calcium-regulated parathyroid hormone secretion in normal volunteers and patients with secondary hyperparathyroidism. J Clin Endocrinol Metabol 76:1489-1494, 1993
9. SANCHEZ CP, GOODMAN WG, RAMIREZ JA, GALES B, BELIN TR, SEGRE GV, SALUSKY IB: Calcium-regulated parathyroid hormone secretion in adynamic renal osteodystrophy. Kidney Int 48:838-843, 1995
10. GOODMAN WG, BELIN T, GALES B, JUPPNER H, SEGRE GV, SALUSKY IB: Calcium-regulated parathyroid hormone release in patients with mild or advanced secondary hyperparathyroidism. Kidney Int 48:1553-1558, 1995
11. GIUSEPPETTI GM, GIOVAGNONI A, BALDELLI S, MACCHINI M, BORDONI E: Correlzaioni Cliniche e Radio-ecotomografiche nell' Iperparatiroidismo Secondario. Radiol Med 72:29-31, 1986
12. JOHNSON WJ, MCCARTHY JT, VAN HEERDEN JA, STERIOFF S, GRANT CS, KAO PC: Results of subtotal parathyroidectomy in hemodialysis patients. Am J Med 84:23-32, 1988
13. MALMAEUS J, GRIMELIUS L, JOHANSSON H, AKERSTROM G, LJUNGHALL S: Parathyroid pathology in hyperparathyroidism secondary to chronic renal failure. Scand J Urol Nephrol 18:157-166, 1984
14. GLADZIWA U, ITTEL TH, DAKSHINAMURTY KV, SCHACHT B, RIEHL J, SIEBERTH H-G: Secondary hyperparathyroidism and sonographic evaluation of parathyroid gland hyperplasia in dialysis patients. Clin Nephrol 38:162-166, 1992
15. BLAND KI, TIDWELL S, VON FRAUNHOFER JA, MORRIS RR, MCCOY MT, WATHEN RL: Intraoperative localization of parathryoid glands using methylothionine chloride tetramethylthionine chloride in secondary hyperparathyroidism. Surgery Gynecol Obstet 160:42-48, 1985
16. BROWN EM: Four-parameter model of the sigmoidal relationship between parathyroid hormone release and extracellular calcium concentration in normal and abnormal parathyroid tissue. J Clin Endocrinol Metabol 56:572-581, 1983
17. KHOSLA S, EBELING PR, FIREK AF, BURRITT MM, KAO PC, HEATH H III: Calcium infusion suggests a "set-point" abnormality of parathyroid gland function in familial benign hypercalcema and more complex disturbances in primary hyperparathyroidism. J Clin Endocrinol Metabol 76:715-720, 1993
18. QUARLES LD, YOHAY DA, CARROLL BA, SPRITZER CE, MINDA SA, BARTHOLOMAY D, LOBAUGH BA: Prospective trial of pulse oral versus intravenous calcitriol treatment of hyperparathyroidism in ESRD. Kidney Int 45:1710-1721, 1994
19. KWAN JTC, ALMOND MK, BEER JC, NOONAN K, EVANS SJW, CUNNINGHAM J: "Pulse" oral calcitriol in uraemic patients: Rapid modification of parathyroid response to calcium. Nephrol Dial Transplant 7:829-834, 1992
20. DUNLAY R, RODRIGUEZ M, FELSENFELD AJ, LLACH F: Direct inhibitory effect of calcitriol on parathyroid function (sigmoidal curve) in dialysis. Kidney Int 36:1093-1098, 1989
21. RODRIGUEZ M, FELSENFELD A, WILLIAMS C, PEDERSON JA, LLACH F: The effect of long-term intravenous calcitriol administration on parathyroid function in hemodialysis patients. J Am Soc Nephrol 2:1014-1020, 1991
22. FERNANDEZ E, BORRAS M, PAIS B, MONTOLIU J: Low calcium dialysate stimulates PTH secretion and its long term use worsens secondary hyperparathyroidism. J Am Soc Nephrol 6:132-135, 1995
23. DELMEZ JA, TINDIRA C, GROOMS P, DUSSO A, WINDUS DW, SLATOPOLSKY E: Parathyroid hormone suppression by intravenous 1,25-dihydroxyvitamin D. A role for increased sensitivity to calcium. J Clin Invest 83:1349-1355, 1989
24. MESSA P, VALLONE C, MIONI G, GEATTI O, TURRIN D, PASSONI N, CRUCIATTI A: Direct in vivo assessment of parathyroid hormone-calcium relationship curve in renal patients. Kidney Int 46:1713-1720, 1994
25. ATTIE JN, KHAN A, RUMANCIK WM, MOSKOWITZ GW, HIRSCH MA, HERMAN PG: Preoperative localization of parathyroid adenomas. Am J Surg 156:323-326, 1988
26. SPRITZER CE, GREFTER WB, HAMILTON R, GREENBERG BM, AXEL L, DRESSEL HV: High resolution MR imaging. Radiology 162:487-491, 1987
27. ROSNER BA: Analysis of variance, in Fundamentals of Biostatistics, edited by ROSNER BA, Belmont, Duxbury Press, 1990, p 474
28. 2+-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Cell 75:1297-1303, 1993
29. NEMETH EF, HEATH H III: The calcium receptor and familial benign hypocalciuric hypercalcemia. Curr Opin Endocrinol Diab 2:556-561, 1995
30. MAYER GP, HABENER JF, POTTS JTJ: Parathyroid hormone secretion in vivo: Demonstration of a calcium-independent nonsuppressible component of secretion. J Clin Invest 57:678-683, 1976
31. GITTES RF, RADDE IC: Experimental model for hyperparathyroidism: Effect of excessive numbers of transplanted isologous parathyroid glands. J Urol 95:595-603, 1966
32. STANBURY SW, LUMB GA: Parathyroid function in chronic renal failure. A statistical survey of the plasma biochemistry in azotaemic renal osteodystrophy. Quart J Med 35:1-23, 1966
33. BLACK WC, SLATOPOLSKY E, ELKAN I, HOFFSTEN P: Parathyroid morphology in suppressible and nonsuppressible renal hyperparathyroidism. Lab Invest 23:497-509, 1970
34. TOFFALETTI J, COOPER DL, LOBAUGH B: The response of parathyroid hormone to specific changes in either ionized calcium, ionized magnesium, or protein-bound calcium in humans. Metabolism 40:814-818, 1991
35. WATHEN RL, KESHAVIAH P, HOMMEYER P, CADWELL K, COMTY CM: The metabolic effects of hemodialysis with and without glucose in the dialysate. Am J Clin Nutr 31:1870-1875, 1978
36. RODRIGO F, SHIDEMAN J, MCHUGH R, BUSELMEIER T, KJELLSTRAND C: Osmolality changes during hemodialysis. Natural history, clinical correlations, and influence of dialysate glucose and intravenous mannitol. Annal Intern Med 86:554-561, 1977
37. HOU SH, ZHAO J, ELLMAN CF, HU J, GRIFFIN Z, SPIEGEL DM, BOURDEAU JE: Calcium and phosphorus fluxes during hemodialysis with low calcium dialysate. Am J Kidney Dis 18:217-224, 1991
38. 4) prescriction prevents parathyroid cell growth in uremic rats and high phosphate directly stimulates PTH secretion in tissue culture. (abstract) J Am Soc Nephrol 6:971, 1995
39. ALI AA, VARGHESE Z, MOORHEAD JF, BAILLOD RA, SWENY P: Calcium set point progressively worsens in hemodialysis patients despite conventional oral 1-α hydroxycholecalciferol supplementation. Clin Nephrol 39:205-209, 1993
40. THOMPSON DB, SAMOWITZ WS, ODELBERG S, DAVID RK, SZABO J, HEATH H III: Genetic abnormalities in sporadic parathyroid adenomas: Loss of heterozygosity for chromosome 3q markers linking the calcium receptor locus. J Clin Endocrinol Metabol 80:3377-3380, 1995
41. FALCHETTI A, BALE AE, AMOROSI A, BORDI C, CICCHI P, BANDINI S, MARX SJ, BRANDI ML: Progression of uremic hyperparathyroidism involves allelic loss on chromosome 11. J Clin Endocrinol Metabol 76:139-144, 1993
42. ARNOLD A, BROWN MF, URENA P, GAZ RD, SARFATI E, DRUEKE TB: Monoclonality of parathyroid tumors in chronic renal failure and in primary parathyroid hyperplasia. J Clin Invest 95:2047-2053, 1995
43. GOGUSEV J, DUCHAMBON P, GIOVANNINI M, SARFATI E, DRUEKE TB: Expression in pathologic parathyroid gland tissue of calcium receptor (CaR) and vitamin D receptor (VDR) gene message (mRNA). (abstract) J Am Soc Nephrol 6:961, 1995