Langerhans cells express inducible nitric oxide synthase and produce nitric oxide

Journal of Investigative Dermatology

Volumn 107, Issue 6, 1996, Pages 815-821

  Qureshi, Abrar A ^a   Hosoi, Junichi ^a   Xu, Shan ^b   Takashima, Akira ^b   Granstein, Richard D ^a   Lerner, Ethan A ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Dendritic cells; L NAME; Mouse

Indexed keywords

GAMMA INTERFERON; LIPOPOLYSACCHARIDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; KERATINOCYTE; LANGERHANS CELL; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0029856133     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12330572     Document Type: Article

References (50)

1. Albina JE, Henry WL: Suppression of lymphocyte proliferation through the nitric oxide synthesizing pathway. J Surg Res 50:403-409, 1991
2. Asahina A, Hosoi J, Beissert S, Stratigos A, Granstein RD: Inhibition of the induction of delayed-type and contact hypersensitivity by calcitonin gene-related peptide. J Immunol 154:3056-3061, 1995
3. Asahina A, Moro O, Hosoi J, Lerner EA, Xu S, Takashima A, Granstein RD: Specific induction of cAMP in Langerhans cells by calcitonin gene-related peptide: relevance to functional effects. Proc Natl Acad Sci USA 92:8323-8327, 1995
4. Baudouin JE, Tachon P: Constitutive nitric oxide synthase is present in normal human keratinocytes. J Invest Dermatol 106:428-431, 1996
5. + normal human keratinocytes. J Clin Invest 93:2275-2279, 1994
6. Becker Y: Success and failure of dendritic cell (DC) anticancer activity may be modulated by nitric oxide synthetase (NOS) gene expression: a hypothesis. In Vivo 7:285-288, 1993
7. Cunha FQ, Moncada S, Liew FY: Interleukin-10 inhibits the induction of nitric oxide synthase by interferon-gamma in murine macrophages. Biochem Biophys Res Commun 182:1155-1159, 1992
8. Cunha FQ, Moss DW, Leal LMCC, Moncada S: Induction of macrophage parasiticidal activity by Staphylococcus aureus and exotoxins through the nitric oxide synthesis pathway. Immunology 78:563-567, 1993
9. Deliconstantinos G, Villiotou V, Stravrides JC: Release by ultraviolet B (u.v.B) radiation of nitric oxide (NO) from human keratinocytes: a potential role for nitric oxide in erythema production. Br J Pharmacol 114:1257-1265, 1995
10. Denis M: Human monocytes/macrophages: NO or no NO? J Leukoc Biol 55:682-684, 1994
11. Edelman GM, Gally JA: Nitric oxide: linking space and time in the brain. Proc Natl Acad Sci USA 89:11651-11652, 1992
12. Genaro AM, Hortelano S, Alvarez A, Martineza C, Bosca L: Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels. J Clin Invest 95:1884-1890, 1995
13. Grabbe S, Bruvers S, Gallo RL, Knisely TL, Nazareno R, Granstein RD: Tumor antigen presentation by murine epidermal cells. J Immunol 146:3656-3661, 1991
14. 15N]nitrate in biological fluids. Anal Biochem 126:131-138, 1982
15. Green, LC, Ruiz de Luzuriaga K, Wagner DA, Rand W, Istfan N, Young VR, Tennenbaum SR: Nitrate biosynthesis in man. Proc Natl Acad Sci USA 78:7764-7768, 1991
16. Heck DE, Laskin DL, Gardner CR, Laskin JD: Epidermal growth factor suppresses nitric oxide production by keratinocytes. J Biol Chem 267:21277-21280, 1992
17. Hennings H, Michael D, Cheng C, Steinert P, Holbrook K, Yuspa SH: Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell 19:245-254, 1980
18. Hosoi J, Murphy GF, Egan CL, Lerner EA, Grabbe S, Asahina A, Granstein RD: Regulation of Langerhans cell function by nerves containing calcitonin generelated peptide. Nature 363:159-163, 1993
19. Hughes SR, Willimas TJ, Brain SD: Evidence that endogenous nitric oxide modulates oedema formation induced by substance P. Eur J Pharmacol 191:481-484, 1990
20. Kaplan G, Walsh G, Guido LS, Meyn P, Burkhardt RA, Abalos RM, Barker J, Frindt PA, Fajardo TT, Celona R: Novel responses of human skin to intradermal recombinant granulocyte/macrophage-colony-stimulating factor: Langerhans cell recruitment, keratinocyte growth, and enhanced wound healing. J Exp Med 1717-1728, 1992
21. Kapsenberg ML, Teunissen MBM, Bos JD: Langerhans cells: a unique subpopulation of antigen presenting dendritic cells. In: Gallo RL, Granstein RD, Staszewsky R, Bos JD (eds.) Skin Immune System. CRC, Boca Raton, FL, 1990, pp 109-124
22. Khan F, Palacino JJ, Cofman JD, Cohen RA: Chronic inhibition of nitric oxide production augments skin vasoconstriction in the rabbit ear. J Cardiovasc Pharmacol 22:280-286, 1993
23. Kimber I, Cumberbatch M: Dendritic cells and cutaneous immune responses to chemical allergens. Toxicol Pharmacol 117:137-146, 1992
24. Kolb-Bachofen V, Fehsel K, Michel G, Ruzicka T: Epidermal keratinocyte expression of inducible nitric oxide synthases in skin lesions of psoriasis vulgaris. Lancet 344:139, 1994
25. Lancaster Jr JR: Simulation of the diffusion and reaction of endogenously produced nitric oxide. Proc Natl Acad Sci USA 91:8137-8141, 1994
26. Liew FY, Cox FEG: Nonspecific defense mechanism: the role of nitric oxide. Immunol Today 12:A17-A21, 1991
27. Liew FY, Millott S, Parkinson C, Palmer RMJ, Moncada S: Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine. J Immunol 144:4794-4797, 1990
28. Lippe IT, Stabentheiner A, Holzer P: Role of nitric oxide in the vasodilator but not exudative component of mustard oil-induced inflammation in rat skin. Agents Actions 38:C21-C23, 1993
29. Lyons CR, Orloff GJ, Cunningham JM: Molecular cloning and functional expression of an inducible nitric oxide synthases from a murine macrophage cell line. J Biol Chem 267:6370-6374, 1992
30. Milstein S, Sakai N, Kaufman S, Saito K, Heyes MP: Role of tetrahydrobiopterin in cytokine-stimulated metabolism of tryptophan and hydroxylation of arginine. In: Ayling JE et al (eds.) Chemistry and Biology of Pteridines and Folates. Plenum Press, New York, 1993, pp 289-294
31. Morita H, Semma M, Hori M, Kitano Y: Clinical applications of nitric oxide synthase inhibitor for atopic dermatitis. Int J Dermatol 34:294, 1995
32. Nathan C: Nitric oxide as a secretory product of mammalian cells. FASEB J 6:3051-3064, 1992
33. Nathan C, Xie Q-W: Regulation of biosynthesis of nitric oxide. J Biol Chem 269:13725-13728, 1994
34. Palmer RM, Ferrige AG, Moncada S: Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327:524-526, 1987
35. Peguet-Navarro J, Moulon C, Schmitt D: The antigen presenting capacity of human epidermal Langerhans cells. Cell Mol Biol 40:15-20, 1994
36. Qureshi AA, Lerner LH, Lerner EA: From bedside to the bench and back: nitric oxide and the cutis. Arch Dermatol, 132:889-893, 1996
37. Roland CR, Walp L, Stack RM, Flye MW: Outcome of Kupffer cell antigen presentation to a cloned murine Th1 lymphocyte depends on the inducibility of nitric oxide synthase by IFN-gamma. J Immunol 153:5453-5464, 1994
38. Romani L, Puccetti P, Mencacci A, Cenci E, Spaccapelo R, Tonnetti L, Grohman U, Bistoni F: Neutralization of IL-10 up-regulates nitric oxide production and protects susceptible mice from challenge with Candida albicans. J Immunol 152:3514-3521, 1994
39. Shijun C, Reichner JS, Mateo RB, Albina JE: Activated murine macrophages induce apoptosis in tumor cells through nitric oxide-dependent or -independent mechanisms. Cancer Res 54:2462-2467, 1994
40. Silberberg-Sinakin I, Thorbecke GJ, Baer RL, Rosenthal SA, Berezowsky V: Antigen-bearing Langerhans colls in skin, dermal lymphocytes and in lymph nodes. Cell Immunol 25:137-151, 1976
41. Snyder SH, Bredt DS: Biological roles of nitric oxide. Sci Am 5:68-77, 1992
42. Stamler JS, Singel DJ, Loscalzo J: Biochemistry of nitric oxide and its redox-activated forms. Science 258:1898-1902, 1992
43. Steinman RM: The dendritic cell system and its role in immunogenicity. Annu Rev Immunol 9:271-296, 1991
44. Stingl G: Dendritic cells of the skin. Dermatol Clin 8:673-679, 1990
45. Takashima A, Edelbaum D, Kitajima T, Shadduck RK, Gilmore GL, Xu S, Taylor RS, Bergstresser PR, Ariizumi K: Colony-stimulating factor-1 secreted by fibroblasts promotes the growth of dendritic cell lines (XS series) derived from murine epidermis. J Immunol 154:5128-5135, 1995
46. Wang R, Ghahary A, Shen YJ, Scott PG, Tredget EE: Human dermal fibroblasts produce nitric oxide and express both the constitutive and inducible nitric oxide synthase isoforms. J Invest Dermatol 106:419-427, 1996
47. Warren JB: Nitric oxide and human skin blood flow responses to acetylcholine and ultraviolet light. FASEB J 8:247-251, 1994
48. Xu S, Ariizumi K, Caceres-Dittmar G, Edelbaum D, Hashimoto K, Bergs tresser PR, Takashima A: Successive generation of antigen-presenting, dendritic cell lines from murine epidermis. J Immunol 154:2697-2705, 1995a
49. Xu S, Ariizumi K, Edelbaum D, Bergstresser PR, Takashima A: Cytokine-dependent regulation growth and maturation in murine epidermal dendritic cell lines. Eur J Immunol 25:1018-1024, 1995b
50. Xie QW, Cho HJ, Calaycay J, Mumford R, Swiderek KM, Lee TB, Ding A, Troso T, Nathan C: Cloning and characterization of inducible nitric oxide synthase from mouse macrophage. Science 256:225-228, 1992