Risk factors for upper gastrointestinal bleeding in intensive care unit patients: Role of Helicobacter pylori

Critical Care Medicine

Volumn 24, Issue 12, 1996, Pages 1974-1981

  Ellison III, Richard T ^a,b,c   Perez Perez, Guillermo ^d   Welsh, Carolyn H ^a,b   Blaser, Martin J ^d   Riester, Katherine A ^e   Cross, Alan S ^f   Donta, Sam T ^a   Peduzzi, Peter ^e  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e DEPARTMENT OF VETERANS AFFAIRS   (United States)

^f WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

critical care; gastritis; gastrointestinal hemorrhage; Helicobacter pylori; immunoglobulin A; intensive care unit; intubation; nasogastric; stomach

Indexed keywords

HYPERIMMUNE GLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G;

ADULT; ALCOHOLISM; ANTIMICROBIAL THERAPY; ARTICLE; BACTERIAL INFECTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIGESTIVE SYSTEM HEMORRHAGE; DIGESTIVE TRACT INTUBATION; DOUBLE BLIND PROCEDURE; ENZYME IMMUNOASSAY; FEMALE; GASTRITIS; HELICOBACTER PYLORI; HUMAN; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOPROPHYLAXIS; INTENSIVE CARE; LIVER FAILURE; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; STRESS ULCER;

EID: 0029855981     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199612000-00008     Document Type: Article

References (33)

1. Czaja AJ, McAlhany JC, Pruitt BAJ: Acute gastroduodenal disease after thermal injury: An endoscopic evaluation of incidence and natural history. N Engl J Med 1974; 291:925-929
2. Kamada T, Fusamoti H, Kawano S, et al: Gastrointestinal bleeding following head injury: A clinical study of 433 cases. J Trauma 1977; 17:44-47
3. Larson GM, Koch S, O'Dorisio TM, et al: Gastric response to severe head injury. Am J Surg 1984; 147:97-105
4. Reusser P, Gyr K, Scheidegger D, et al: Prospective endoscopic study of stress erosions and ulcers in critically ill neurosurgical patients: Current incidence and effect of acid-reducing prophylaxis. Crit Care Med 1990; 18: 270-274
5. Eddleston JM, Pearson RC, Holland J, et al: Prospective endoscopic study of stress erosions and ulcers in critically ill adult patients treated with either sucralfate or placebo. Crit Care Med 1994; 22:1949-1954
6. Eddleston JM, Vohra A, Scott P, et al: A comparison of the frequency of stress ulceration and secondary pneumonia in sucralfate- or ranitidine-treated intensive care unit patients. Crit Care Med 1991; 19:1491-1496
7. Shuman RB, Schuster DP, Zuckerman GR: Prophylactic therapy for stress ulcer bleeding: A reappraisal. Ann Intern Med 1987; 106:562-567
8. Prod'hom G, Leuenberger P, Koerfer J, et al: Nosocomial pneumonia in mechanically ventilated patients receiving antacid, ranitidine, or sucralfate as prophylaxis for stress ulcer. A randomized control trial. Ann Intern Med 1994; 120:653-662
9. Cook DJ, Fuller HD, Guyatt GH, et al: Risk factors for gastrointestinal bleeding in critically ill patients. N Engl J Med 1994; 330:377-381
10. Schuster DP, Rowley H, Feinstein S, et al: Prospective evaluation of the risk of upper gastrointestinal bleeding after admission to a medical intensive care unit. Am J Med 1984; 76:623-630
11. Ben-Menachem T, Fogel R, Patel RV, et al: Prophylaxis for stress-related gastric hemorrhage in the medical intensive care unit. A randomized, controlled, single-blind study. Ann Intern Med 1994; 121:568-575
12. Craven DE, Kunches LM, Kilinsky V, et al: Risk factors for pneumonia and fatality in patients receiving continuous mechanical ventilation. Am Rev Respir Dis 1986; 133:792-796
13. Tryba M: Risk of acute stress bleeding and nosocomial pneumonia in ventilated intensive care unit patients: Sucralfate versus antacids. Am J Med 1987; 83(Suppl 3B):117-124
14. Driks MR, Craven DE, Celli BR, et al: Nosocomial pneumonia in intubated patients given sucralfate as compared with antacids or histamine type 2 blockers. N Engl J Med 1987; 317:1376-1382
15. Dooley CP, Cohen H, Fitzgibbons PL, et al: Prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic persons. N Engl J Med 1989; 321:1562-1566
16. Dooley CP, Cohen H: The clinical significance of Campylobacter pylori. Ann Intern Med 1988; 108:70-79
17. Cover TL, Blaser MJ: Helicobacter pylori and gastroduodenal disease. Annu Rev Med 1992; 43:135-145
18. Strauss RM, Wang TC, Kelsey PB, et al: Association of Helicobacter pylori infection with dyspeptic symptoms in patients undergoing gastroduodenoscopy. Am J Med 1990; 89:464-469
19. Perez-Perez GI, Dworkin BD, Chodos JE, et al: Campylobacter pylori antibodies in humans. Ann Intern Med 1988; 109:11-17
20. Donta ST, Peduzzi P, Cross AS, et al: Immunoprophylaxis against Klebsiella and Pseudomonas infections. J Infect Dis 1996; 174:537-543
21. Drumm B, Perez-Perez GI, Blaser MJ, et al: Intrafamilial clustering of Helicobacter pylori infection. N Engl J Med 1990; 322:359-363
22. Efron B: Bootstrap methods: Another look at the jackknife. Annals of Statistics 1979; 7:1-26
23. Hanley JA, McNeil BJ: The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 1982; 143:29-36
24. Bresalier RS: The clinical significance and pathophysiology of stress-related gastric mucosal hemorrhage. Clin Gastroenterol 1991; 13:S35-S43
25. Anonymous: Stress ulcer prophylaxis in critically ill patients. Lancet 1989; ii:1255-1256
26. Blaser MJ: Helicobacter pylori and the pathogenesis of gastroduodenal inflammation. J Infect Dis 1990; 161:626-633
27. Rauws EAJ, Langenberg W, Houthoff HJ, et al: Campylobacter pyloridis-associated chronic active antral gastritis. A prospective study of its prevalence and the effects of antibacterial and antiulcer treatment. Gastroenterology 1988; 94:33-40
28. Marshall BJ, Warren JR: Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984; i:1311-1313
29. Perez-Perez GI, Brown WR, Cover TL, et al: Correlation between serological and mucosal inflammatory responses to Helicobacter pylori. Clinical and Diagnostic Laboratory Immunology 1994; 1:325-329
30. Luzza F, Maletta M, Imeneo M, et al: Isotypic pattern of Helicobacter pylori antibody response in gastric mucosa, saliva and serum. Abstr. Clin Immunol Immunopathol 1995; 76:S20
31. Cook DJ, Pearl RG, Cook RJ, et al: Incidence of clinically important bleeding in mechanically ventilated patients. J Intensive Care Med 1991; 6:167-174
32. Weinstein WM: Gastritis and inflammatory disorders of the stomach. In: Gastroenterologic Endoscopy. Sivak MVJ (Ed). Philadelphia, WB Saunders, 1987, pp 454-474
33. Isenberg JI, McQuaid KR, Laine L, et al: Acid-peptic disorders. In: Textbook of Gastroenterology. Yamada T, Alpers DH, Owyang C, et al (Eds). Philadelphia, JB Lippincott, 1991, pp 1241-1339