Cysteines 153 and 154 of transmembrane transforming growth factor-α are palmitoylated and mediate cytoplasmic protein association

Journal of Biological Chemistry

Volumn 271, Issue 45, 1996, Pages 28502-28508

  Shum, Lillian ^a   Turck, Christoph W ^b   Derynck, Rik ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; MEMBRANE PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL COMMUNICATION; CHO CELL; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

ANIMALS; CHO CELLS; CRICETINAE; CYSTEINE; CYTOPLASM; MEMBRANE PROTEINS; MUTAGENESIS, SITE-DIRECTED; PALMITIC ACID; PLASMIDS; TRANSFORMING GROWTH FACTOR ALPHA;

ANIMALIA;

EID: 0029855770     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.45.28502     Document Type: Article

References (62)

1. Derynck, R., Roberts, A. B., Winkler, M. E., Chen, E. Y., and Goeddel, D. V. (1984) Cell 38, 287-297
2. Marquardt, H., Hunkapiller, M. W., Hood, L. E., and Todaro, G. J. (1984) Science 223, 1079-1082
3. Lee, D. C., Rochford, R., Todaro, G. J., and Villarreal, L. P. (1985) Mol. Cell. Biol. 5, 3644-3646
4. Massague, J. (1983) J. Biol. Chem. 258, 13614-13620
5. Derynck, R. (1992) Adv. Canner Res. 58, 27-52
6. Brachmann, R., Lindquist, P. B., Nagashima, M., Kohr, W., Lipari, T., Napier, M., and Derynck, R. (1989) Cell 58, 691-700
7. Wong, S. T., Winchell, L. F., McCune, B. K., Earp, H. S., Teixido, J., Massague, J., Herman, B., and Lee, D. C. (1989) Cell 56, 495-506
8. Wilcox, J. N., and Derynck, R. (1988) Mol. Cell. Biol. 8, 3415-3422
9. Derynck, R., Goeddel, D. V., Ullrich, A., Gutterman, J. U., Williams, R. D., Bringman, T. S., and Berger, W. H. (1987) Cancer Res. 47, 707-712
10. Elder, J. T., Fisher, G. J., Lindquist, P. B., Bennett, G. L., Pittelkow, M. R., Coffey, R. J., Ellingsworth, L., Derynck, R., and Voorhees, J. J. (1989) Science 243, 811-814
11. Dempsey, P. J., Goldenring, J. R., Soroka, C. J., Modlin, I. M., McClure, R. W., Lind, C. D., Ahlquist, D. A., Pittelkow, M. R., Lee, D. C., Sandgren, E. P., Page, D. L., and Coffey, R. J. (1992) Gastroenterology 103, 1950-1963
12. Takagi, H., Jhappan, C., Sharp, R., and Merlino, G. (1992) J. Clin. Invest. 90, 1161-1167
13. Savage, C. R., Jr., and Cohen, S. (1972) J. Biol. Chem. 247, 7609-7611
14. Savage, C. R., Jr., Inagami, T., and Cohen, S. (1972) J. Biol. Chem. 247, 7612-7621
15. Gray, A., Dull, T. J., and Ullrich, A. (1983) Nature 303, 722-725
16. Scott, J., Urdea, M., Quiroga, M., Sanchez-Pescador, R., Fong, N., Selby, M., Rutter, W. J., and Bell, G. I. (1983) Science 221, 236-240
17. Shoyab, M., Plowman, G. D., McDonald, V. L., Bradley, J. G., and Todaro, G. J. (1989) Science 243, 1074-1076
18. Plowman, G. D., Green, J. M., Culouscou, J. M., Carlton, G. W., Rothwell, V. M., and Buckley, S. (1993) Nature 366, 473-475
19. Higashiyama, S., Abraham, J. A., Miller, J., Fiddes, J. C., and Klagsbrun, M. (1991) Science 251, 936-939
20. Shing, Y., Christofori, G., Hanahan, D., Ono, Y., Sasada, R., Igarashi, K., and Folkman, J. (1993) Science 259, 1604-1607
21. Stroobant, P., Rice, A. P., Gullick, W. J., Cheng, D. J., Kerr, I. M., and Waterfield, M. D. (1985) Cell 42, 383-393
22. Holmes, W. E., Sliwkowski, M. X., Akita, R. W., Henzel, W. J., Lee, J., Park, J. W., Yansura, D., Abadi, N., Raab, H., Lewis, G. D., Shepard, H. M., Kuang, W. J., Wood, W. I., Goeddel, D. V., and Vandlen, R. L. (1992) Science 256, 1205-1210
23. Wen, D., Peles, E., Cupples, R., Suggs, S. V., Bacus, S. S., Luo, Y., Trail, G., Hu, S., Silbiger, S. M., Levy, R. B., Koski, R. A., Lu, H. S., and Yarden, Y. (1992) Cell 69, 559-572
24. Falls, D. L., Rosen, K. M., Corfas, G., Lane, W. S., and Fischbach, G. D. (1993) Cell 72, 801-815
25. Marchionni, M. A., Goodearl, A. D., Chen, M. S., Bermingham-McDonogh, O., Kirk, C., Hendricks, M., Danehy, F., Misumi, D., Sudhalter, J., Kobayashi, K., Wroblewski, D., Lynch, C., Baldassare, M., Hiles, I., Davis, J. B., Hsuan, J. J., Totty, N, F., Otsu, M., McBurney, R. N., Waterfield, M. D., Stroobant, P., and Gwynne, D. (1993) Nature 362, 312-318
26. Hill, R. J., and Sternberg, P. W. (1992) Nature 358, 470-476
27. Rutledge, B. J., Zhang, K., Bier, E., Jan, Y. N., and Perrimon, N. (1992) Genes Dev. 6, 1503-1517
28. Neuman-Silberberg, F. S., and Schupbach, T. (1993) Cell 75, 165-174
29. Zurfluh, L. L., Bolten, S. L., Byatt, J. C., McGrath, M. F., Tou, J. S., Zupec, M. E., and Krivi, G. G. (1990) Growth Factors 3, 257-266
30. Chiang, T., McBride, J., Chou, M. Y., Nishimura, I., and Wong, D. T. (1991) Carcinogenesis 12, 529-532
31. Sutton, R., Ward, W. G., Raphael, K. A., and Cam, G. R. (1995) Comp. Biochem. Physiol. 110, 697-705
32. Higashiyama, S., Iwamoto, R., Goishi, K., Raab, G., Taniguchi, N., Klagsbrun, M., and Mekada, E. (1995) J. Cell Biol. 128, 929-938
33. Bosenberg, M. W., Pandiella, A., and Massague, J. (1992) Cell 71, 1157-1165
34. Shum, L., Reeves, S. A., Kuo, A. C., Fromer, E. S., and Derynck, R. (1994) J. Cell. Biol. 125, 903-916
35. Shaw, A. S., Amrein, K. E., Hammond, C., Stern, D. F., Sefton, B. M., and Rose, J. K. (1989) Cell 59, 627-636
36. Shaw, A. S., Chalupny, J., Whitney, J. A., Hammond, C., Amrein, K. E., Kavathas, P., Sefton, B. M., and Rose, J. K. (1990) Mol. Cell. Biol. 10, 1853-1862
37. Turner, J. M., Brodsky, M. H., Irving, B. A., Levin, S. D., Perlmutter, R. M., and Littman, D. R. (1990) Cell 60, 755-765
38. Bringman, T. S., Lindquist, P. B., and Derynck, R. (1987) Cell 48, 429-440
39. Schmidt, M. F. (1989) Biochim. Biophys. Acta 988, 411-426
40. James, G., and Olson, E. N. (1990) Biochemistry 29, 2623-2634
41. Ross, E. M. (1995) Curr. Biol. 5, 107-109
42. Hancock, J. F., Paterson, H., and Marshall, C. J. (1990) Cell 63, 133-139
43. Magee, A.I., Newman, C. M., Giannakouros, T., Hancock, J. F., Fawell, E., and Armstrong, J. (1992) Biochem. Soc. Trans. 20, 497-499
44. Wedegaertner, P. B., and Bourne, H. R. (1994) Cell 77, 1063-1070
45. Schultz, A. M., Henderson, L. E., and Oroszlan, S. (1988) Annu. Rev. Cell Biol. 4, 611-647
46. Towler, D. A., Gordon, J. I., Adams, S. P., and Glaser, L. (1988) Annu. Rev. Biochem. 57, 69-99
47. Dautigny, A., Alliel, P. M., d'Auriol, L., Pham, D., Nussbaum, J. L., Galibert, F., and Jolles, P. (1985) FEES Lett. 188, 33-36
48. Stoffel, W., Killen, H., Schroder, W., and Deutzmann, R. (1983) Hoppe-Seylers Z. Physiol. Chem. 364, 1455-1466
49. Hackett, M., Guo, L., Shabanowitz, J., Hunt, D. F., and Hewlett, E. L. (1994) Science 266, 433-435
50. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular cloning: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
51. Kaufman, J. F., Krangel, M. S., and Strominger, J. L. (1984) J. Biol. Chem. 259, 7230-7238
52. Glenn, G. M., and Eckhart, W. (1993) J. Virol. 67, 1945-1952
53. Macauley, S. L., Polites, M., Frenkel, M. J., Hewish, D. R., and Ward, C. W. (1995) Biochem. J. 306, 811-820
54. Paige, L. A., Nadler, M. J. S., Harrison, M. L., Cassady, J. M., and Geahlen, R. L. (1993) J. Biol. Chem. 268, 8669-8674
55. Resh, M. D. (1994) Cell 76, 411-413
56. Shenoy-Scaria, A. M., Gauen, L. K., Kwong, J., Shaw, A. S., and Lublin, D. M. (1993) Mol. Cell. Biol. 13, 6385-6392
57. Shenoy-Scaria, A. M., Dietzen, D. J., Kwong, J., Link, D. C., and Lublin, D. M. (1994) J. Cell Biol. 126, 353-363
58. Wedegaertner, P. B., Wilson, P. T., and Bourne, H. R. (1995) J. Biol. Chem. 270, 503-506
59. Harano, T., and Mizuno, K. (1994) J. Biol. Chem. 269, 20305-20311
60. Pandiella, A., and Massagué, J. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 1726-1730
61. Pandiella, A., and Massagué, J. (1991) J. Biol. Chem. 266, 5769-5773
62. Baselga, J., Mendelsohn, J., Kim, Y.-M., and Pandiella, A. (1996) J. Biol. Chem. 271, 3279-3284