Detection of the metastatic potential of blood-borne and immunomagnetically enriched epithelial cells by quantitative erbB-2 RT-PCR

Clinical and Experimental Metastasis

Volumn 14, Issue 4, 1996, Pages 399-408

  Brandt, B ^a   Griwatz, C ^b   Heidl, S ^a   Assmann, G ^a   Zanker K S ^b  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF WITTEN HERDECKE   (Germany)

Author keywords

Adjuvant therapy; Blood borne epithelial cells; Hematogenous metastasis; MRNA c erbB 2 dosage; Quantitative competitive RT PCR

Indexed keywords

MESSENGER RNA;

ARTICLE; BLOOD CELL; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; METASTASIS POTENTIAL; ONCOGENE C ERB; QUANTITATIVE ASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL;

ADENOCARCINOMA; BREAST NEOPLASMS; EPITHELIAL CELLS; EPITHELIUM; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, ERBB-2; HUMANS; MAGNETICS; NEOPLASM CIRCULATING CELLS; ONCOGENE PROTEINS V-ERBB; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0029855756     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00123399     Document Type: Article

References (24)

1. Clark WH, 1991, Tumor progression and the nature of cancer. Br J Cancer, 64, 631-44.
2. Moll R, Franke WW, Schiller DL, Geiger B and Krepier R, 1982, The catalog of human cytokeratins: patterns of expression in normal epithelia, tumours and cultured cells. Cell, 31, 11-32.
3. Griwatz C, Brandt B, Assmann G and Zänker KS, 1995, An immunological enrichment method for epithelial cells from peripheral blood. J Immunol Meth, 183, 251-65.
4. Hirokoshi T, Danenberg KD, Stadtbauer et al. 1992, Quantification of thymidylate synthase, dihydrofolate reductase, and DT-diaphorase gene expression in human tumors using the polymerase chain reaction. Cancer Res, 52, 108-16.
5. Benz CC, Brandt BH and Zänker KS, 1995, Gene diagnostics provide new insights into breast cancer prognosis and therapy. Gene, 159, 3-7.
6. Brandt B, Vogt U, Harms F, Jacksich C, Assmann G and Zänker KS, 1993, Breast cancer prognosis: identification of high-risk patients by erbB-2 and c-myc oncogene amplification. Proc Amer Soc Clin Oncol, 12, 237.
7. Brandt B, Vogt U, et al. 1994, Estimation of average gene copy number of erbB-1, erbB-2, and erbB-3 for prognosis in breast cancer. Proc Amer Assoc Cancer Res, 35, 212.
8. Semba K, Kamata N, Toyoshima K and Yamamoto T, 1985, A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma. Proc Natl Acad Sci USA, 82, 6497-501.
9. Ishii S, Xu YH, Stratton RH, Roe BA, Merlino GT and Pastan I, 1985, Characterisation and sequence of the promoter region of the human epidermal growth factor receptor gene. Proc Natl Acad Sci USA, 82, 4920-4.
10. Brandt B, Vogt U, Harms F, Bosse U, Zänker KS and Assmann G, 1995, Double-differential PCR for gene dosage estimation of erbB oncogenes in benign and cancer tissues, and comparison to cellular DNA content. Gene, 159, 29-34.
11. Fidler IJ, 1990, Critical factors in the biology of human cancer metastasis: twenty-eight. G.H.A. Clowes Memorial Award Lecture. Cancer Res, 50, 6130.
12. Friedl P, Noble PB, Walton PA, et al. 1995, Migration of coordinated cell clusters in mesenchymal and epithelial cancer explants in vitro. Cancer Res, 55, 4557-60.
13. Slamon DJ, Godolphin W, Jones LA, et al. 1989, Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science, 244, 707-12.
14. Sarkar FH, Visscher DW and Crissman JD, 1993, Quantitative analysis of Her-2/neu (ERBB2) gene expression using reverse transcriptase polymerase chain reaction. Diagn Mol Pathol, 2, 210-18.
15. Weis W, Moritz D, Schmidt M, Jeschke M, Hynes NE and Groner B, 1995, Biotechnological and gene therapeutic strategies in cancer treatment. Gene, 159, 73-80.
16. Morrison C and Gannon F, 1994, The impact of the plateau phase on quantitative PCR. Biochim Biophys Acta, 1219, 493-8.
17. Datta YH, Adams PT, Drobyski WR, Ethier SP, Terry VH and Roth MS, 1994, Sensitive detection of occult breast cancer by the reverse-transcriptase polymerase chain reaction. J Clin Onco, 12, 475-82.
18. Neumeier M, Gerhard M and Wagener C, 1995, Diagnosis of micromelastases by the amplification of tissue-specific genes. Gene, 159, 43-7.
19. Burchill S, Bradbiry M, Pittman K, Southgate L, Smith B and Selhy P, 1995, Detection of epithelial cancer cells in peripheral blood by reverse transcriptase-polymearse chain reaction. Br J Cancer, 71, 278-83.
20. Mull R, Schiller DL and Franke WW, 1990, Idetification of protein IT of the intestinal cytoskeleton as anovel type I cytokeratin with unusual properties and expression patterns. J Cell Biol, 111, 576-80.
21. Gerhard M, Juhl H, Kalthoff H, Schreiber HW, Wagener C and Neumeier M, 1994, Specific detection of carcinoembryonic antigen-expressing tumor cells in hone marrow aspirates by polymerase chain reaction. J Clin Oncol, 14, 235-8.
22. Tsai, CM, Chang KT, Perng RP, et al. 1993, Correlation of intrinsic chemoresistance of non-small cell lung cancer cell lines with Her-2/neu gene expression hut not with ras gene mutations. J Natl Cancer Inst, 85, 897-901.
23. Schlimok G, Funke I, Pantel K, et al. 1991, Micrometastatic tumour cells in bone marrow of patients with gastric cancer: methodological aspects of detection and prognostic significance. Eur J Cancer, 27, 1461-5.
24. Pantel K, Schlimok G, Braun S, et al. 1993, Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells. J Natl Cancer Inst, 85, 1419-23.