T cells and orbital connective tissue in endocrine orbitopathy

Experimental and Clinical Endocrinology and Diabetes

Volumn 104, Issue SUPPL. 4, 1996, Pages 79-83

  Kahaly, G ^a,c   Otto, E ^a   Forster G ^a   Gansen, K ^a   Olivari, N ^b   Beyer, J ^a   Hansen, Ch ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b Dreifaltigkeits Hospital   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Autologous T cells; Endocrine orbitopathy; Glycosaminoglycans; Orbital antigens

Indexed keywords

GLYCOSAMINOGLYCAN; HYALURONIC ACID;

CLINICAL ARTICLE; CONFERENCE PAPER; CONNECTIVE TISSUE; CONTROLLED STUDY; ENDOCRINE DISEASE; EXTRACELLULAR MATRIX; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTE PROLIFERATION; ORBIT DISEASE; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0029855523     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0029-1211708     Document Type: Conference Paper

References (10)

1. Arnold K, Tandon N, McIntosh RS, Elisei R, Ludgate M, Weetman AP: T cell responses to orbital antigens in thyroid-associated ophthalmopathy. Clin Exp Immunol 96: 329-334, 1994
2. Burch HB, Wartofsky L: Graves' Ophthalmopathy. Current concepts regarding patho genesis and management. Endocr Rev 14: 747-793, 1993
3. + and specifically recognize autologous fibroblasts. J Clin Invest 93:2738-2743, 1994
4. Kahaly G, Stover C, Otto E, Beyer J, Schuler M: Glycosaminoglycans in Thyroid-Associated Ophthalmopathy. Autoimmunity 13: 81-88, 1992
5. Kahaly G, Hansen C, Felke B, Dienes HP: Immunohistochemical staining of retrobulbar adipose tissue in Graves' ophthalmopathy. Clin Immunol Immunopathol 73: 53-62, 1994
6. McLachlan SM, Prummel MF, Rapoport B: Cell-mediated or humoral immunity in Graves' ophthalmopathy? Profiles of T-cell cytokines amplified by polymerase chain reaction from orbital tissue. J Clin Endocrinol Metab 78: 1070-1074, 1994
7. Otto E, Ochs K, Hansen C, Wall J, Kahaly G: Orbital tissue-derived T lymphocytes from patients with Graves' ophthalmopathy recognize autologous orbital antigens. J Clin Endocrinol Metab 81, August, 1996
8. Stover C, Otto E, Beyer J, Kahaly G: Cellular immunity and retrobulbar fibroblasts in Graves' ophthalmopathy. Thyroid 4: 161-165, 1994
9. Tan GH, Dutton CM, Bahn RS: Interleukin-1 (IL-1) receptor antagonist and soluble IL-1 receptor inhibit IL-1-induced glycosaminoglycan production in cultured human orbital fibroblasts from patients with Graves' ophthalmopathy. J Clin Endocrinol Metab 81: 449-452, 1996
10. Weetman AP, McGregor AM: Autoimmune thyroid disease: further developments in our understanding. Endocr Rev 15: 788-830, 1994