Complexity in O-linked oligosaccharide biosynthesis engendered by multiple polypeptide N-acetylgalactosaminyltransferases

Glycobiology

Volumn 6, Issue 7, 1996, Pages 701-705

  Marth, Jamey D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Biosynthesis; O glycan; Vertebrate

Indexed keywords

ISOENZYME; N ACETYLGLUCOSAMINYLTRANSFERASE;

BIOSYNTHESIS; CARBOHYDRATE SYNTHESIS; ENZYME ACTIVITY; ENZYME SPECIFICITY; GENE EXPRESSION REGULATION; HUMAN; IN VITRO STUDY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS; SEQUENCE HOMOLOGY; SHORT SURVEY; SPECIES DIFFERENCE;

VERTEBRATA;

EID: 0029854853     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/6.7.701     Document Type: Short Survey

References (42)

1. Abeijon,C and Hirschberg,C.B. (1987) Subcellular site of synthesis of the N-acetylgalactosamine (a1-0) serine (or threonine) linkage in rate liver. J. Biol. Chem., 262, 4153-4159.
2. Baum,L.G., Derbin,K., Perillo,N.L., Wu,T., Pang,M. and Uittenbogaart (1996) Characterization of terminal sialic acid linkages on human thymocytes. J. Biol. Chem., 271, 10793-10799.
3. Chou,K-C., Zhang,C-T., Kézdy,F.J. and Poorman,R.A. (1995) A vector projection method for predicting the specificity of GalNAc-transferase. Proteins, 21, 118-126.
4. Cummings,R.D., Kornfeld,S., Schneider,W.J., Hobgood,K.K., Tolleshaug,H., Brown,M S. and Goldstein,J.L. (1983) Biosynthesis of N- and O-linked oligosaccharides of the low density lipoprotein receptor. J. Biol. Chem., 258, 15261-15273.
5. Deschuyteneer,M., Eckhardt,A.E., Roth,J. and Hill,R.L. (1988) The subcellular localization of apomucin and nonreducing terminal N-acetylgalactosamine in porcine submaxillary glands. J. Biol. Chem., 263, 2452-2459.
6. Elhammer,Å. and Kornfeld,S. (1984) Two enzymes involved in the synthesis of O-linked oligosaccharides are localized on membranes of different densities in mouse lymphoma BW5147 cells. J. Cell Biol., 98, 327-331.
7. Elhammer,Å. and Kornfeld,S. (1986) Purification and characterization of UDP-N-acetylgalactosamine: polypeptide N-acetylgalactosaminyltransferase from bovine colostrum and murine lymphoma BW5147 cells. J. Biol. Chem., 261, 5249-5255.
8. Elhammer,Å.P., Poorman,R.A., Brown,E., Maggiora,L.L., Hoogerheide,J.G. and Kézdy,F.J. (1993) The specificity of UDP-GalNAc: polypeptide N-acetylgalactosaminyltrasferase as inferred from a database on in vivo substrates and from the in vitro glycosylation of proteins and peptides. J. Biol. Chem., 268, 10029-10038.
9. Ellinger,A and Pavelka,M. (1992) Subdomains of the rough endoplasmic reticulum in colon goblet cells of the rat: lectin-cytochemical characterization. J. Histochem. Cytochem., 40, 919-930.
10. Gillespie,W., Paulson,J.C., Kelm,S., Pang,M. and Baum,L.G. (1993) Regulation of α2,3-sialyltransferase expression correlates with conversion of peanut agglutinin (PNA)+ to PNA- phenotype in developing thymocytes. J. Biol. Chem., 268, 3801-3804.
11. Hagen,F.K., VanWuyckhuyse,B. and Tabak,L.A. (1993) Purification, cloning, and expression of a bovine UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase. J. Biol. Chem., 268, 18960-18965.
12. Hagen,F.K., Gregoire,C.A and Tabak,L.A. (1995) Cloning and sequence homology of rat UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase. Glycoconjugate J., 12, 901-909.
13. Hagopian,A. and Eylar,E.H (1969) Glycoprotein biosynthesis: the purification and characterization of a polypeptide: N-acetylgalactosaminyl transferase from bovine submaxillary glands. Arch. Biochem. Biophys., 129, 515-524.
14. Hanover,J.A., Elting,J., Mintz,G.R and Lennarz,W.J. (1982) Temporal aspects of the N- and O-glycosylation of human chononic gonadotropin. J. Biol. Chem., 257, 10172-10177.
15. Hennet,T., Hagen,F.K., Tabak,L.A. and Marth,J.D. (1995) T-Cell-specific deletion of a polypeptide N-acetylgalactosaminyltransferase gene by site-directed recombination. Proc. Natl. Acad. Sci. USA, 92, 12070-12074.
16. Hill,H.D., Schwyzer,M., Steinman,H.M. and Hill,R.L. (1977) Ovine submaxillary mucin: primary structure and peptide substrates of UDP-N-acetylgalactosamine:mucin transferase. J. Biol. Chem., 252, 3799-3804.
17. Homa,F.L., Hollander,T , Lehman,D.J., Thomsen,D.R. and Elhammer,Å.P. (1993) Isolation and expression of a cDNA clone encoding a bovine UDP- GalNAc:Polypeptide N-acetylgalactosaminyltransferase. J. Biol. Chem., 268, 12609-12616.
18. Ioffe,E. and Stanley,P. (1994) Mice lacking N-acetylglucosaminyltransferase I activity die at midgestation, revealing an essential role for complex or hybrid N-linked carbohydrates. Proc. Natl. Acad Sci. USA, 91, 728-732.
19. Lowe,J.B., Stoolman,L.M., Nair,R.P., Larsen,R.D., Berhend,T.L. and Marks,R.M. (1990) ELAM-1-dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA. Cell, 63, 475-484.
20. Maly,P., Thall,A.D., Petryniak,B., Rogers,C E., Smith,P.L., Marks,R.M., Kelly,R.J., Gersten,K.M., Cheng,G., Saunders,T.L., Camper,S.A., Camphausen,R.T., Sullivan,F.X., Isogai,Y., Hindsgaul,O., von Adrian,U.H. and Lowe,J.B. (1996) The α(1,3)Fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell, 86, 643-653.
21. Marth,J.D. (1996) Recent advances in gene mutagenesis by site-directed recombination. J. Clin. Invest., 97, 1999-2002.
22. Metzler,M., Gertz,A., Sarkar,M , Schachter,H., Schrader,J.W. and Marth,J.D. (1994) Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development. EMBO J., 13, 2056-2065.
23. Meurer,J.A., Drong,R.F., Homa,F.L., Slightom,J.L. and Elhammer,Å.P. (1996) Organization of a human UDP-GalNAc:polypeptide, N-acetylgalactosaminyltransferase gene and a related processed pseudogene. Glycobiology, 6, 231-241.
24. Nehrke,K., Hagen,F.K. and Tabak,L.A. (1996) Charge distribution of flanking amino acids influences O-glycan acquisition in vivo. J. Biol. Chem., 271, 7061-7065.
25. O'Connell,B., Tabak,L.A., and Ramasubbu,N. (1991) The influence of flanking sequences on O-glycosylation. Biochem. Biophys. Res. Commun., 180, 1024-1030.
26. O'Connell,B.C., Hagen,F.K. and Tabak,L.A. (1992) The influence of flanking sequence on the O-glycosylation of threonine in vitro. J. Biol. Chem., 267, 25010-25018.
27. Patzelt,C. and Weber,B. (1986) Early O-glycosidic giycosylation of proglucagon in pancreatic islets: an unusual type of prohormonal modification. EMBO J., 5, 2103-2108.
28. Perez-Vilar,J., Hidalgo,J. and Velasco,A. (1991) Presence of terminal N-acetylgalactosamine residues in subregions of the endoplasmic reticulum is influenced by cell differentiation in culture. J. Biol. Chem., 266, 23967-23976.
29. Piller, V., Piller,F. and Fukuda,M. (1990) Biosynthesis of truncated O-glycans in the T cell line jurkat. J. Biol. Chem., 265, 9264-9271.
30. Powell,L.D., Sgroi,D., Sjoberg,E.R., Stamenkovic,I. and Varki,A. (1993) natural ligands of the B cell adhesion molecule CD22β carry N-linked oligosaccharides with α2,6-linked sialic acids that are required for recognition. J. Biol. Chem., 268, 7019-7027.
31. Pownall,S., Kozak,C.A., Schappert,K., Sarkar,M., Hull,E., Schachter,H. and Marth,J.D. (1992) Molecular cloning and characterization of the mouse UDP-N-acetylglucosamine:α-3-D-mannoside β-1,2-N-acetylglucosaminyltransferase I gene. Genomics, 12, 699-704.
32. Roth,J. (1984) Cytochemical localization of terminal N-acetyl-D-galactosamine residues in cellular compartments of intestinal goblet cells: implication for the topology of O-glycosyiation. J. Cell Biol., 98, 399-406
33. Roth,J., Wang,Y., Eckhardt,A.E. and Hill,R.L. (1994) Subcellular localization of the UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase-mediated O-glycosylation reaction in the submaxillary gland. Proc. Natl. Acad. Sci. USA, 91, 8935-8939.
34. Schweizer,A., Clausen,H., van Meer,G and Hauri,H.-P. (1994) Localization of O-Glycan initiation, sphingomyelin synthesis, and glucosylceramide synthesis in vero cells with respect to the endoplasmic reticulum-golgi intermediate compartment. J. Biol. Chem., 269, 4035-4041.
35. Sgroi,D., Varki,A., Braesch-Andersen,S. and Stamenkovic,I. (1993) CD22, a B cell-specific immunoglobulin superfamily member, is a sialic acid-binding lectin. J. Biol. Chem., 268, 7011-7018.
36. Sorenson,T., White,T., Wandall,H.H., Kristensen,A.K., Roepstorff,P. and Clausen,H. (1995) UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase. J. Biol. Chem., 270, 24166-24173.
37. Strous,G.J.A.M. (1979) Initial giycosylation of proteins with acetylgalactosaminylserine linkages. Proc. Natl. Acad. Sci. USA, 76, 2694-2698.
38. Sugiura,M., Kawasaki,T. and Yamashma,I. (1982) Purification and characterization of UDP-GalNAc: polypeptide N-acetylgalactosamine transferase from an ascites hepatoma. AH 66. J. Biol. Chem., 257, 9501-9507.
39. Wang,Y., Abemathy,J.L., Eckhardt,A.E. and Hill,R.L. (1992) Purification and characterization of a UDP-GalNAc:polypeptide N-acetylgalactosaminyl- transferase specific for glycosylation of threonine residues. J. Biol. Chem., 267, 12709-12716.
40. Wang,Y , Neera,A., Eckhardt,A E., Stevens,R.D. and Hill,R.L. (1993) The acceptor substrate specificity of porcine submaxillary UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase is dependent on the amino acid sequences adjacent to serine and threonine residues. J. Biol Chem., 268, 22979-22983.
41. White,T., Bennett,E.P., Takio,K., Sorenson,T., Bonding,N and Clausen,H. (1995) Purification and cDNA cloning of a human UDP-N-acetyl-α-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase. J. Biol. Chem., 270, 24156-24165.
42. Wilson,I.B.H., Gavel,Y. and von Heijne,G. (1991) Amino acid distributions around O-linked glycosylation sites. Biochem. J., 275, 529-534.