Evaluation of interleukin 10 and interferon-α in the cerebrospinal fluid and serum of patients with multiple sclerosis

European Journal of Neurology

Volumn 3, Issue 6, 1996, Pages 544-547

  Carrieri, P B ^a   Maiorino, A ^a   Provitera, V ^a   Perrella, A ^b   Perrella, O ^b,c  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b AO Dei Colli Hospital for Infectious Diseases D Cotugno   (Italy)

^c NONE   (Italy)

Author keywords

Cerebrospinal fluid; Inflammation; Interferon ; Interleukin 10; Multiple sclerosis

Indexed keywords

ALPHA INTERFERON; CYTOKINE; INTERLEUKIN 10;

ADULT; ARTICLE; B LYMPHOCYTE; BLOOD LEVEL; CEREBROSPINAL FLUID LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HELPER CELL; HUMAN; MACROPHAGE; MALE; MONOCYTE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; REMISSION;

EID: 0029854727     PISSN: 13515101     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1468-1331.1996.tb00271.x     Document Type: Article

References (11)

1. Brosnan CF, Selmaj K and Raine CS (1988) A role for tumor necrosis factor in immune-mediated demyelination and its relevance to multiple sclerosis. Journal of Neuroimmunology, 18, 87-94.
2. De Waal Malefyt R, Abrams J, Bennet B, Fidgor CG and De Vries JE (1991) Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. Journal of Experimental Medicine, 174, 1209-1220.
3. Link H, Tibbling G (1977) Principles of albumin and IgG analyses in neurological disorders: III. Evaluation of IgG synthesis within the central nervous system in multiple sclerosis. Scandinavian Journal of Clinic and Laboratory Investigation, 37, 397-409.
4. Loughlin AJ, Woodroofe MN and Cuzner ML (1992) Regulation of Fc receptor and major hystocompatibility complex antigen expression on isolated rat microglia by tumor necrosis factor, interleukin-1 and lipopolysaccharide: effects on interferon-gamma-induced activation. Immunology,75, 170-175.
5. Olsson T (1994) Role of cytokines in multiple sclerosis and experimental autoimmune encephalomyelitis. European Journal of Neurology, 1, 7-19.
6. + in patients with multiple sclerosis. European Neurology, 33, 152-155.
7. Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC, Johnson KP, Sibley WA, Silberberg DA and Tourtellotte WW (1983) New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Annals of Neurology, 13, 227-233.
8. Rieckmann P, Albrecht M, Kitze B et al. (1994) Cytokine mRNA levels in mononuclear blood cells from patients with multiple sclerosis. Neurology, 44, 1523-1526.
9. Rott O, Fleisher B and Cash E (1994) Interleukin-10 prevents experimental allergic encephalomyelitis in rats. European Journal of Immunology, 24, 1434-1440.
10. Shattner A (1994) Lymphokines in autoimmunity - a critical review. Clinical Immunology and Immunopathology, 70, 177-184.
11. Woodroofe MN (1995) Cytokine production in the central nervous system. Neurology, 45, S6-S10.