Distribution of neurokinin-2 receptors in the guinea-pig gastrointestinal tract

Cell and Tissue Research

Volumn 286, Issue 3, 1996, Pages 281-292

  Portbury, Andrea L ^a   Furness, John B ^a   Southwell, Bridget R ^a   Wong, Helen ^b   Walsh, John H ^b   Bunnett, Nigel W ^c  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Enteric nervous system; Gastrointestinal tract; Guinea pig; Peptide Receptors; Smooth muscle; Tachykinins

Indexed keywords

NEUROKININ 2 RECEPTOR;

ANIMAL TISSUE; ARTICLE; ASCENDING COLON; CECUM; ESOPHAGUS; FEMALE; GANGLION; GASTROINTESTINAL MUCOSA; ILEUM; IMMUNOHISTOCHEMISTRY; INTERNEURON; INTESTINE CELL; LARGE INTESTINE; MALE; MYENTERIC PLEXUS; NONHUMAN; PRIORITY JOURNAL; SMALL INTESTINE; STOMACH;

ANIMALS; AXONS; DENERVATION; DIGESTIVE SYSTEM; FEMALE; GUINEA PIGS; ILEUM; MALE; RECEPTORS, NEUROKININ-2;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0029854653     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410050698     Document Type: Article

References (51)

1. Barlhó L, Holzer P (1985) Search for a physiological role of substance Pin gastrointestinal motility. Neuroscience 16:1-32
2. Barthó L, Holzer P, Lembeck F (1989) Evidence for an involvement of substance P, but not cholecystokinin-like peptides, in hexamethonium-resistant intestinal peristalsis. Neuroscience 28:211-217
3. A receptors at GABAergic synaptic contacts demonstrated by triple immunofluorescence staining. Brain Res 642:59-69
4. Burcher E, Mussap CJ (1991) Neuropeptide γ-preferring subtypes of NK-2 receptors in rat fundus and dog urinary bladder. Soc Neurosci Abstr 17: 805
5. Burcher E, Stamatakos C (1994) Septide but not substance P stimulates inhibitory neurons in guinea-pig ileum. Eur J Pharmacol 258:R9-R10
6. Burcher E, Buck SH, Lovenberg W, O'Donohue TL (1986) Characterization and autoradiographic localization of multiple tachykinin binding sites in gastrointestinal tract and bladder. J Pharmacol Exp Ther 236:819-831
7. Costa M, Brookes SJH, Waterman S, Mayo R (1992) Enteric neuronal circuitry and transmitters controlling intestinal motor function. In: Holle GE, Wood JP (eds) Advances in the innervation of the gastrointestinal tract. Elsevier Science, Amsterdam, pp 115-121
8. Cuello AC, Galfre G, Milstein C (1979) Detection of substance P in the central nervous system by a monoclonal antibody. Proc Nutl Acad Sci USA 76:3532-3536
9. Cuttitta F, Carney DN, Mulshine J, Moody TW, Fedorko J, Fischler A, Minna JD (1985) Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer. Nature 316:823-826
10. Dion S, D'Orleans-Juste P, Drapeau G, Rhaleb N-E, Rouissi N, Tousignant C, Regoli D (1987) Characterization of neurokinin receptors in various isolated organs by the use of selective agonists. Life Sci 41:2269-2278
11. Donnerer J, Holzer P, Lembeck F (1984) Release of dynorphin, somatostatin and substance P from the vascularly perfused small intestine of the guinea-pig during peristalsis. Br J Pharmacol 83:919-925
12. Ekblad E, Winther C, Ekman R, Håkanson R, Sundler F (1987) Projections of peptide-containing neurons in rat small intestine. Neuroscience 20:169-188
13. Euler US von, Gaddum JH (1931) An unidentified depressor substance in certain tissue extracts. J Physiol (Lond) 72:74-87
14. 125I-labelled alpha bungarotoxin binding at mouse motor endplates. Proc Natl Acad Sci 7:1376-1378
15. Furness JB, Costa M (1987) The enteric nervous system. Churchill Livingstone, Edinburgh
16. Furness JB, Pompolo S, Murphy R, Giraud A (1989) Projections of neurons with neuromedin U-like immunoreactivity in the small intestine of the guinea-pig. Cell Tissue Res 257: 415-422
17. Grady EF, Baluk P, Bohm S, Gamp PD, Wong H, Payan DG, Ansel J, Portbury AL, Furness JB, McDonald DM, Bunnett NW (1996) Localisation of NK1, NK2 and NK3 tachykinin receptors in cell lines and in the gastrointestinal tract using specific antibodies. J Neurosci (in press)
18. Harris AJ, Kuffler SW, Dennis MJ (1971) Differential chemosensitivity of synaptic and extrasynaptic areas on the neuronal surface membrane in parasympathetic neurons of the frog, tested by microapplication of acetylcholine. Proc R Soc Lond B 177:541-533
19. Hirst CDS, Bramich NJ, Edwards FR, Klemm M (1992) Transmission at autonomie neuroeffector junctions. Trends Neurosci 15:40-46
20. Huber O, Bertrand C, Bunnett NW, Pellegrini CA, Nadel JA, Debas HT, Gepetti P (1993) Tachykinins contract the circular muscle of the human esophageal body in vitro via NK2 receptors. Gastroenterology 105:981-987
21. Jacoby HI, Lopez I, Wright D, Vaught JL (1986) Differentiation of multiple neurokinin receptors in the guinea-pig ileum. Life Sci 39:1995-2003
22. Jin J-G, Grider JR, Makhlouf GM (1993) Functional difference between SP and NKA: relaxation of gastric muscle by SP is mediated by VIP and NO. Am J Physiol 264:G678-G685
23. Kachur JF, Miller RJ, Field M, Rivier J (1982) Neurohumoral control of ileal electrolyte transport. II. Neurotensin and substance P. J Pharmacol Exp Ther 220:456-463
24. Katayama Y, North RA, Williams JT (1979) The action of substance P on neurons of the myenteric plexus of the guinea-pig small intestine. Proc R Soc Lond B 206:191-208
25. Kuffler SW (1943) Specific excitability of the endplate region in normal and denervated muscle. J Neurophysiol 6:99-110
26. Langley JN (1907) On the contraction of muscle, chiefly in relation to the presence of "receptive" substances. Part I. J Physiol (Lond) 36:347-384
27. Laufer R, Gilon C, Chorev M, Selinger Z (1988) Desensitization with a selective agonist discriminates between multiple tachykinin receptors. J Pharmacol Exp Ther 245:639-643
28. Liu H, Brown JL, Jasmin L, Maggio JE, Vigna SR, Mantyh PW, Basbaum AI (1994) Synaptic relationship between substance P and the substance P receptor: light and electron microscopic characterization of the mismatch between neuropeptides and their receptors. Proc Natl Acad Sci USA 91:1009-1013
29. Maggi CA, Patacchini R, Giachetti A, Meli A (1990) Tachykinin receptors in the circular muscle of the guinea-pig ileum. Br J Pharmacol 996-1000
30. Maggi CA, Giuliani S, Patacchini R, Santiciolo P, Theodorsson E, Barbanti G, Turini D, Giachetti A (1992) Tachykinin antagonists inhibit nerve-mediated contractions in the circular muscle of the human ileum. Gastroenterology 102:88-96
31. Maggi CA, Patacchini R, Rovero P, Giachetti A (1993) Tachykinin receptors and tachykinin receptor antagonists. J Auton Pharmacol 13:23-93
32. 2 receptor antagonists and atropine-resistant ascending excitatory reflex to the circular muscle of the guinea-pig ileum. Br J Pharmacol 112:161-168
33. 2 receptors in the circular muscle of the guineapig ileum and proximal colon. Br J Pharmacol 112:150-160
34. McConalogue K, Furness JB (1994) Gastrointestinal neurotransmitters. In: Fuller P, Shulkes A (eds) The gut as an endocrine organ. Baillière Tindall, London, pp 51-76
35. Mihara S, Nishi S (1994) Neurokinin A mimics the slow excitatory postsynaptic current in submucous plexus neurons of the guinea-pig caecum. Neuroscience 62:1245-1255
36. Morita K, North RA, Katayama Y (1980) Evidence that substance P is a neurotransmitter in the myenteric plexus. Nature 287:151-152
37. Nusser Z, Mulvihill E, Streit P, Somogyi P (1994) Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization. Neuroscience 61:421-427
38. A receptors on cerebellar granule cells as determined by a quantitative immunogold method. J Neurosci 15:2948-2960
39. Perdue MH, Galbraith R, Davison JS (1987) Evidence for substance P as a functional neurotransmitter in guinea pig small intestinal mucosa. Regul Pept 18:63-74
40. Petitet F, Saffroy M, Torrens Y, Lavielle S, Chassaing G, Loeuillet D, Glowinski J, Beaujouan JC (1992) Possible existence of a new tachykinin receptor subtype in the guinea-pig ileum. Peptides 13:383-388
41. Portbury AL, Furness JB, Young HM, Southwell BR, Vigna SR (1996) Localisation of NK1 receptor immunoreactivity to neurons and interstitial cells of the guinea-pig gastrointestinal tract. J Comp Neurol 367:342-351
42. Sevcik J, Kadlec O, Seferna I (1990) The effect of substance P on nerve action potential propagation and cholinergic transmission in the myenteric plexus of the guinea-pig ileum. Naunyn Schmiedebergs Arch Pharmacol 341:56-61
43. Shuttleworth CWR, Murphy R, Furness JB, Pompolo S (1991) Comparison of the presence and actions of substance P and neurokinin A in guinea-pig taenia coli. Neuropeptides 19:23-34
44. Sternini C, Su D, Gamp PD, Bunnett NW (1995) Cellular sites of expression of the neurokinin-1 receptor in the rat gastrointestinal tract. J Comp Neurol 358:531-540
45. Takeda Y, Krause JE (1991) Pharmacological and molecular biological studies on the diversity of rat tachykinin NK-2 receptor subtypes in rat CNS, duodenum, vas deferens and urinary bladder. Ann NY Acad Sci 632:479-482
46. Uemura S, Pompolo S, Furness JB (1995) Colocalization of neuropeptide Y with other neurochemical markers in the guineapig small intestine. Arch Histol Cytol 58:523-536
47. Vigna SR, Bowden JJ, McDonald DM, Fisher J, Okamoto A, McVey DC, Payan DG, Bunnett NW (1994) Charaeterization of antibodies to the rat substance P (NK-1) receptor and to a chimeric substance P receptor expressed in mammalian cells. J Neurosci 14:834-845
48. Yau WM, Youther ML (1982) Direct evidence for a release of acelylcholine from the myenteric plexus of guinea pig small intestine by substance P. Eur J Pharmacol 81:665-668
49. Yau WM, Youther ML, Verdun PR (1985) A presynaptic site of action of substance P and vasoactive intestinal polypeptide on myenteric neurons. Brain Res 330:382-385
50. 2 receptors mediate non-cholinergic excitatory junction potentials in the circular muscle of guinea-pig colon. Br J Pharmacol 110:795-803
51. 2 receptors mediate non-adrenergic non-cholinergic excitation and contraction in the circular muscle of guinea-pig duodenum. Br J Pharmacol 115: 237-246