Contribution of the renin-angiotensin system to short-term blood pressure variability during blockade of nitric oxide synthesis in the rat

British Journal of Pharmacology

Volumn 119, Issue 6, 1996, Pages 1085-1092

  Gouédard, Olivier ^a   Blanc, Jocelyne ^a   Gaudet, Elisabeth ^a   Ponchon, Pascal ^a   Elghozi, Jean Luc ^a  

^a Laboratoire de Pharmacologie CNRS URA 1482   (France)

Author keywords

Arterial pressure; Losartan; N(G) nitro L arginine methyl ester (L name); Spectral analysis

Indexed keywords

ARGININE METHYL ESTER; LOSARTAN; NITRIC OXIDE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE; BRADYCARDIA; CONTROLLED STUDY; DOSE RESPONSE; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SPECTROSCOPY; TACHYCARDIA;

EID: 0029854095     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb16008.x     Document Type: Article

References (42)

1. AKSELROD, S., ELIASH, S., OZ, O. & COHEN, S. (1987). Hemodynamic regulation in SHR: investigation by spectral analysis. Am. J. Physiol., 253, H176-H183.
2. BAYLIS, C., ENGELS, K., SAMSELL, L. & HARTON, P. (1993). Renal effects of acute endothelial-derived relaxing factor blockade are not mediated by angiotensin II. Am. J. Physiol., (Renal Fluid Electrolyte. Physiol., 33), 264, F74-F78.
3. BAYLIS, C., HARTON, P. & ENGELS, K. (1990). Endothelium-derived relaxing factor controls renal hemodynamics in the normal rat kidney. J. Am. Soc. Nephrol., 1, 875-881.
4. BROWN, D.R., BROWN, L.V., PATWARDHAN, A. & RANDALL, D.C. (1994). Sympathetic activity and blood pressure are tightly coupled at 0.4 Hz in conscious rats. Am. J. Physiol., (Regulatory Integrative Comp. Physiol., 36), 267, R1378-R1384.
5. G-nitro-L-arginine methyl ester to the rat on inhibition of nitric oxidemediated responses. Br. J. Pharmacol., 114, 1673-1679.
6. G-nitro-L-arginine methyl ester and other alkyl esters of arginine are muscarinic receptor antagonists. Circ. Res., 72, 387-395.
7. CERUTTI, C., GUSTIN, M.P., PAULTRE, C.Z., LO, M., JULIEN, C., VINCENT, M. & SASSARD, J. (1991). Autonomic nervous system and cardiovascular variability in rats: a spectral analysis approach. Am. J. Physiol., 261, H1292-H1299.
8. CERUTTI, C., BARRES, C. & PAULTRE, C. (1994). Baroreflex modulation of blood pressure variability in rats : assessment by spectral analysis. Am. J. Physiol., 266 (Heart Circ. Physiol., 35), H1993-H2000.
9. CONRAD, K.P. & WHITTEMORE, S.L. (1992). NG-monomethyl-L-arginine and nitroarginine potentiate pressor responsiveness of vasoconstrictors in conscious rats. Am. J. Physiol., (Regulatory Integrative Comp. Physiol., 31), 262, R1137-R1144.
10. ω-Monomethyl-L-Arginine on short-term RR interval and systolic blood pressure oscillations. J. Cardiovasc. Pharmacol., 24, 323-327.
11. DAFFONCHIO, A., FRANZELLI, C., DI RIENZO, M., CASTIGLIONI, P., RAMIREZ, A.J., PARATI, G., MANCIA, G. & FERRARI, A.U. (1991). Effect of sympathectomy on blood pressure variability in the conscious rat. J. Hypertens, 9 (suppl 6), S70-S71.
12. DI RIENZO, M., PARATI, G., CASTIGLIONI, P., OMBONI, S., FERRARI, A.U., RAMIREZ, A.J., PEDOTTI, A. & MANCIA, G. (1991). Role of sinoaortic afferents in modulating BP and pulse-interval spectral characteristics in unanesthetized cats. Am. J. Physiol., 261 (Heart Circ. Physiol., 30), H1811-H1818.
13. GARDINER, S.M. & BENNETT, T. (1992). Involvement of nitric oxide in the regional haemodynamic effects of perindoprilat and captopril in hypovolaemic Brattleboro rats. Br. J. Pharmacol., 107, 1181-1191.
14. G-nitro-L-arginine methyl ester in conscious Long Evans rats. Br. J. Pharmacol., 101, 625-631.
15. GAUDET, E., BLANC, J. & ELGHOZI, J.L. (1995). Effects of losartan on short-term variability of blood pressure in SHR and WKY rats. Fundam. Clin. Pharmacol., 9, 30-36.
16. GRICHOIS, M.L., BLANC, J., DECKERT, V. & ELGHOZI, J.L. (1992). Differential effects of enalapril and hydralazine on short-term variability of blood pressure and heart rate in rats. J. Cardiovasc. Pharmacol., 19, 863-869.
17. HASSER, E.M. & BISHOP, V.S. (1988). Neurogenic and humoral factors maintaining arterial pressure in conscious dogs. Am. J. Physiol., (Regulatory Integrative Comp. Physiol., 36), 255, R693-R698.
18. JAPUNDZIC, N., GRICHOIS, M.L., ZITOUN, P., LAUDE, D. & ELGHOZI, J.L. (1990). Spectral analysis of blood pressure and heart rate in conscious rats: effects of autonomie blockers. J. Auton. Nerv. Syst., 30, 91-100.
19. JOHNSON, R.A. & FREEMAN, R.H. (1992). Pressure natriuresis in rats during blockade of the L-arginine/nitric oxide pathway. Hypertension, 19, 333-338.
20. JUST, A., WITTMANN, U., NAFZ, B., WAGNER, C.D., EHMKE, H., KIRCHHEIM, H.R. & PERSSON, P.B. (1994). The blood pressure buffering capacity of nitric oxide by comparison to the baroreceptor reflex. Am. J. Physiol., (Heart Circ. Physiol., 36), 267, H521-H527.
21. KUMAGAI, H., AVERILL, D.B., KHOSLA, M.C. & FERRARIO, C.M. (1993). Role of nitric oxide and angiotensin II in the regulation of sympathetic nerve activity in spontaneously hypertensive rats. Hypertension, 21, 476-484.
22. G-nitro-L-arginine methyl ester on renal function and blood pressure. Am. J. Physiol., (Renal Fluid Electrolyte Physiol., 30), 261, F1033-F1039.
23. G-nitro-L-arginine methyl ester-induced hypertension. J. Hypertens., 12, 791-795.
24. LO, M., JULIEN, C., BARRES, C., MEDEIROS, I., ALLEVARD, A.M., VINCENT, M. & SASSARD, J. (1991). Blood pressure maintenance in hypertensive sympathectomized rats. II. Renin-angiotensin system and vasopressin. Am. J. Physiol., (Regulatory Integrative Comp. Physiol., 30), 261, R1052-R1056.
25. MONCADA, S., PALMER, R.M.J. & HIGGS, E.A. (1991). Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev., 43, 109-142.
26. ω-Nitro-L-Arginine methyl ester administration. J. Cardiovasc. Pharmacol., 23, 765-771.
27. NAFZ, B., JUST, A., STAUSS, H.M., WAGNER, C.D., EHMKE, H., KIRCHHEIM, H.R. & PERSSON, P.B. (1996). Blood pressure variability is buffered by nitric oxide. J. Auton. Nerv. Syst., 57, 181-183.
28. PERSSON, P.B. (1996). Modulation of cardiovascular control mechanisms and their interaction. Physiol Rev., 76, 193-244.
29. PERSSON, P.B., BAUMANN, J.E., EHMKE, H., NAFZB, B., WITTMANN, U. & KIRCHHEIM, H.R. (1992a). Phasic and 24-h blood pressure control by endothelium-derived relaxing factor in conscious dogs. Am. J. Physiol., (Heart Circ. Physiol., 31), 262, H1395-H1400.
30. PERSSON, P.B., STAUSS, H., CHUNG, O., WITTMANN, U. & UNGER, T. (1992b). Spectrum analysis of sympathetic nerve activity and blood pressure in conscious rats. Am. J. Physiol., (Heart Circ. Physiol., 32), 263, H1348-H1355.
31. PONCHON, P. & ELGHOZI, J.L. (1996). Contribution of the reninangiotensin and kallikrein-kinin systems to short-term variability of blood pressure in two-kidney, one-clip hypertensive rats. Eur. J. Pharmacol., 297, 61-70.
32. REES, D.D., PALMER, R.M.J. & HIGGS, E.A. (1989). Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc. Natl. Acad. Sci. U.S.A., 86, 3375-3378.
33. REID, I.A. & CHIU, Y.J. (1995). Nitric oxide and the control of renin secretion. Fundam. Clin. Pharmacol., 9, 309-323.
34. RICHARD, V., HOGIE, M., CLOZEL, M., LOFFLER, B.M. & THUILLEZ, C. (1995). In vivo evidence of an endothelial-induced vasopressor tone after inhibition of nitric oxide synthesis in rats. Circulation, 91, 771-775.
35. G-methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo. Circ. Res., 70, 607-611.
36. G-nitro-L-arginine methyl ester treatment in conscious rats. Hypertension, 23, 982-986.
37. SIGMON, D.H., CARRETERO, O.A. & BEIERWALTES, W.H. (1992). Endothelium-derived relaxing factor regulates renin release in vivo. Am. J. Physiol., (Renal Fluid Electrolyte. Physiol., 32), 263, F256-F261.
38. G-nitro-L-arginine by halothane. J. Cardiovasc. Pharmacol., 22, 571-578.
39. WANG, Y.X., GAVRAS, I., WIERZBA, T., LAMMEK, B. & GAVRAS, H. (1992). Inhibition of nitric oxide, bradykinin, and prostaglandins in normal rats. Hypertension, 19 [suppl II], II-255-II-261.
40. G-nitro-L-arginine methyl ester (L-NAME) of resistance to venous return in rats. Br. J. Pharmacol., 114, 1454-1458.
41. ZATZ, R. & DE NUCCI, G. (1991). Effects of acute nitric oxide inhibition on rat glomerular microcirculation. Am. J. Physiol., (Renal Fluid Electrolyte. Physiol., 33), 261, F360-F363.
42. ZHANG, Z.Q., BARRES, C. & JULIEN, C (1992). Nitric oxide synthesis and the control of blood pressure in sympathectomized rats. In Genetic Hypertension, ed. Sassard, J., Vol. 218, pp. 27-29. Colloque INSERM/John Libbey Eurotext Ltd.