Pharmacokinetics of piperacillin, tazobactam and its metabolite in renal impairment

International Journal of Clinical Pharmacology and Therapeutics

Volumn 34, Issue 11, 1996, Pages 482-488

  Derendorf, H ^a   Dalla Costa, T ^a  

^a UNIVERSITY OF FLORIDA HEALTH   (United States)

Author keywords

Pharmacokinetics; Piperacillin; Renal impairment; Tazobactam

Indexed keywords

DRUG METABOLITE; PIPERACILLIN; TAZOBACTAM;

ARTICLE; CLINICAL TRIAL; CREATININE CLEARANCE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG ELIMINATION; DRUG METABOLISM; DRUG URINE LEVEL; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY FAILURE;

DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; ENZYME INHIBITORS; HALF-LIFE; HUMANS; KIDNEY DISEASES; PENICILLANIC ACID; PENICILLINS; PIPERACILLIN;

EID: 0029853527     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (2)

1. Halstenson CE, Wong MO, Johnson CA, Zimmermann SW, Onorato JJ, Keane WF, Doepner M, Sia L, Tantitlo K, Bansal S, Kuye O, Yacobi A, Faulkner R, Lathia CD 1994 Phannacokinetics of tazobactam M1 metabolite after administration of piperacillin/tazobactam in subjects with renal impairment. J Clin Pharmacol 34: 1208-1217
2. Johnson CA, Halstenson CE, Kelloway JS, Shapiro BE, Zimmermann SW, Tonelli A, Faulkner R, Dutta A, Haynes J. Greene DS 1992 Singledose pharmacokinetics of piperacillin and tazobactam in subjects with renal disease. Clin Pharm Ther 51: 32-41